Compile Data Set for Download or QSAR

Found 35 hits Enz. Inhib. hit(s) with Target = 'Platelet-activating factor acetylhydrolase IB subunit alpha2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50132713 (Arachidonic acid derivative | CHEMBL113262 | Methy...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCP(F)(=O)OC Show InChI InChI=1S/C21H36FO2P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(22,23)24-2/h7-8,10-11,13-14,16-17H,3-6,9,12,15,18-21H2,1-2H3/b8-7-,11-10-,14-13-,17-16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154536 (2-(4-tert-butylphenyl)-1-(4-methylbenzenesulfonyl)...) Show SMILES Cc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C)C(O)=O |c:10| Show InChI InChI=1S/C30H33NO4S/c1-20-6-10-22(11-7-20)27-19-18-26(29(32)33)28(23-12-14-24(15-13-23)30(3,4)5)31(27)36(34,35)25-16-8-21(2)9-17-25/h6-18,27-28H,19H2,1-5H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154531 (2-(4-bromophenyl)-6-(4-chlorophenyl)-1-(4-methylbe...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1C(CC=C(C1c1ccc(Br)cc1)C(O)=O)c1ccc(Cl)cc1 |c:14| Show InChI InChI=1S/C25H21BrClNO4S/c1-16-2-12-21(13-3-16)33(31,32)28-23(17-6-10-20(27)11-7-17)15-14-22(25(29)30)24(28)18-4-8-19(26)9-5-18/h2-14,23-24H,15H2,1H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154529 (2-(4-fluorophenyl)-1-(4-methylbenzenesulfonyl)-6-[...) Show SMILES CC(C)c1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(F)cc1)C(O)=O |c:12| Show InChI InChI=1S/C28H28FNO4S/c1-18(2)20-6-8-21(9-7-20)26-17-16-25(28(31)32)27(22-10-12-23(29)13-11-22)30(26)35(33,34)24-14-4-19(3)5-15-24/h4-16,18,26-27H,17H2,1-3H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154534 (2-(4-bromophenyl)-6-(3,4-dichlorophenyl)-1-(4-meth...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N1C(CC=C(C1c1ccc(Br)cc1)C(O)=O)c1ccc(Cl)c(Cl)c1 |c:14| Show InChI InChI=1S/C25H20BrCl2NO4S/c1-15-2-9-19(10-3-15)34(32,33)29-23(17-6-12-21(27)22(28)14-17)13-11-20(25(30)31)24(29)16-4-7-18(26)8-5-16/h2-12,14,23-24H,13H2,1H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154540 (2-(4-(tert-butyl)phenyl)-N-(2-methoxyethyl)-6-(p-t...) Show SMILES COCCNC(=O)C1=CCC(N(C1c1ccc(cc1)C(C)(C)C)S(=O)(=O)c1ccc(C)cc1)c1ccc(C)cc1 |t:7| Show InChI InChI=1S/C33H40N2O4S/c1-23-7-11-25(12-8-23)30-20-19-29(32(36)34-21-22-39-6)31(26-13-15-27(16-14-26)33(3,4)5)35(30)40(37,38)28-17-9-24(2)10-18-28/h7-19,30-31H,20-22H2,1-6H3,(H,34,36)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154535 (2-(4-fluorophenyl)-1-(4-methylbenzenesulfonyl)-6-(...) Show SMILES Cc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(F)cc1)C(O)=O |c:10| Show InChI InChI=1S/C26H24FNO4S/c1-17-3-7-19(8-4-17)24-16-15-23(26(29)30)25(20-9-11-21(27)12-10-20)28(24)33(31,32)22-13-5-18(2)6-14-22/h3-15,24-25H,16H2,1-2H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188239 (CHEMBL3827161) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(Cc1ccc2OCOc2c1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)CCOC)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C65H78BrClN16O17S/c1-96-30-24-54(85)72-80(61(92)41-83-65(95)100-63(74-83)52-23-22-51(101-52)44-13-17-46(66)18-14-44)39-59(90)81(73-62(93)45-15-19-47(67)20-16-45)40-60(91)82(75-64(94)71-48-10-4-3-5-11-48)38-58(89)79(33-43-12-21-49-50(32-43)99-42-98-49)37-57(88)78(29-31-97-2)36-56(87)77(28-9-7-26-69)35-55(86)76(34-53(70)84)27-8-6-25-68/h3-5,10-23,32H,6-9,24-31,33-42,68-69H2,1-2H3,(H2,70,84)(H,72,85)(H,73,93)(H2,71,75,94)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188244 (CHEMBL3828405) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccc(Br)cc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C49H58Br2ClN13O11S/c1-75-25-24-62(28-42(68)61(23-5-3-21-54)27-41(67)60(26-40(55)66)22-4-2-20-53)43(69)29-64(59-48(73)56-37-16-12-35(51)13-17-37)44(70)30-63(57-46(72)33-8-14-36(52)15-9-33)45(71)31-65-49(74)76-47(58-65)39-19-18-38(77-39)32-6-10-34(50)11-7-32/h6-19H,2-5,20-31,53-54H2,1H3,(H2,55,66)(H,57,72)(H2,56,59,73)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of FP-Rh probe binding to recombinant PAFAH1B2 (unknown origin) doped in human HeLa cell lysate incubated for 30 mins followed by FP-Rh pr...				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188240 (CHEMBL3827226) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)c1ccc(OC)cc1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)Cc1ccccc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C69H79BrClN17O16S/c1-102-36-35-83(40-59(92)82(34-12-10-32-73)39-58(91)81(38-56(74)89)33-11-9-31-72)60(93)41-85(77-66(99)49-21-27-53(103-2)28-22-49)62(95)44-87(80-68(100)75-52-15-7-4-8-16-52)63(96)43-86(78-65(98)48-19-25-51(71)26-20-48)61(94)42-84(76-57(90)37-46-13-5-3-6-14-46)64(97)45-88-69(101)104-67(79-88)55-30-29-54(105-55)47-17-23-50(70)24-18-47/h3-8,13-30H,9-12,31-45,72-73H2,1-2H3,(H2,74,89)(H,76,90)(H,77,99)(H,78,98)(H2,75,80,100)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188242 (CHEMBL3827685) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccc(cc1)N(C)C)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C51H64BrClN14O11S/c1-61(2)39-18-16-38(17-19-39)57-50(75)60-66(31-45(71)64(26-27-77-3)30-44(70)63(25-7-5-23-55)29-43(69)62(28-42(56)68)24-6-4-22-54)46(72)32-65(58-48(74)35-10-14-37(53)15-11-35)47(73)33-67-51(76)78-49(59-67)41-21-20-40(79-41)34-8-12-36(52)13-9-34/h8-21H,4-7,22-33,54-55H2,1-3H3,(H2,56,68)(H,58,74)(H2,57,60,75)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188238 (CHEMBL3827906) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C49H59BrClN13O11S/c1-74-26-25-61(29-42(67)60(24-8-6-22-53)28-41(66)59(27-40(54)65)23-7-5-21-52)43(68)30-63(58-48(72)55-37-9-3-2-4-10-37)44(69)31-62(56-46(71)34-13-17-36(51)18-14-34)45(70)32-64-49(73)75-47(57-64)39-20-19-38(76-39)33-11-15-35(50)16-12-33/h2-4,9-20H,5-8,21-32,52-53H2,1H3,(H2,54,65)(H,56,71)(H2,55,58,72)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154530 (1-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)-6-[...) Show SMILES CC(C)c1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(C)cc1)C(O)=O |c:12| Show InChI InChI=1S/C29H31NO4S/c1-19(2)22-11-13-23(14-12-22)27-18-17-26(29(31)32)28(24-9-5-20(3)6-10-24)30(27)35(33,34)25-15-7-21(4)8-16-25/h5-17,19,27-28H,18H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154542 (5-(bromomethyl)-6-(4-(tert-butyl)phenyl)-2-(p-toly...) Show SMILES Cc1ccc(cc1)C1CC=C(CBr)C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C |t:10| Show InChI InChI=1S/C30H34BrNO2S/c1-21-6-10-23(11-7-21)28-19-14-25(20-31)29(24-12-15-26(16-13-24)30(3,4)5)32(28)35(33,34)27-17-8-22(2)9-18-27/h6-18,28-29H,19-20H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188243 (CHEMBL3828611) Show SMILES NC(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C14H10BrN3O3S/c15-9-3-1-8(2-4-9)10-5-6-11(22-10)13-17-18(7-12(16)19)14(20)21-13/h1-6H,7H2,(H2,16,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188244 (CHEMBL3828405) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccc(Br)cc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C49H58Br2ClN13O11S/c1-75-25-24-62(28-42(68)61(23-5-3-21-54)27-41(67)60(26-40(55)66)22-4-2-20-53)43(69)29-64(59-48(73)56-37-16-12-35(51)13-17-37)44(70)30-63(57-46(72)33-8-14-36(52)15-9-33)45(71)31-65-49(74)76-47(58-65)39-19-18-38(77-39)32-6-10-34(50)11-7-32/h6-19H,2-5,20-31,53-54H2,1H3,(H2,55,66)(H,57,72)(H2,56,59,73)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188238 (CHEMBL3827906) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C49H59BrClN13O11S/c1-74-26-25-61(29-42(67)60(24-8-6-22-53)28-41(66)59(27-40(54)65)23-7-5-21-52)43(68)30-63(58-48(72)55-37-9-3-2-4-10-37)44(69)31-62(56-46(71)34-13-17-36(51)18-14-34)45(70)32-64-49(73)75-47(57-64)39-20-19-38(76-39)33-11-15-35(50)16-12-33/h2-4,9-20H,5-8,21-32,52-53H2,1H3,(H2,54,65)(H,56,71)(H2,55,58,72)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188240 (CHEMBL3827226) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)c1ccc(OC)cc1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)Cc1ccccc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C69H79BrClN17O16S/c1-102-36-35-83(40-59(92)82(34-12-10-32-73)39-58(91)81(38-56(74)89)33-11-9-31-72)60(93)41-85(77-66(99)49-21-27-53(103-2)28-22-49)62(95)44-87(80-68(100)75-52-15-7-4-8-16-52)63(96)43-86(78-65(98)48-19-25-51(71)26-20-48)61(94)42-84(76-57(90)37-46-13-5-3-6-14-46)64(97)45-88-69(101)104-67(79-88)55-30-29-54(105-55)47-17-23-50(70)24-18-47/h3-8,13-30H,9-12,31-45,72-73H2,1-2H3,(H2,74,89)(H,76,90)(H,77,99)(H,78,98)(H2,75,80,100)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188242 (CHEMBL3827685) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccc(cc1)N(C)C)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C51H64BrClN14O11S/c1-61(2)39-18-16-38(17-19-39)57-50(75)60-66(31-45(71)64(26-27-77-3)30-44(70)63(25-7-5-23-55)29-43(69)62(28-42(56)68)24-6-4-22-54)46(72)32-65(58-48(74)35-10-14-37(53)15-11-35)47(73)33-67-51(76)78-49(59-67)41-21-20-40(79-41)34-8-12-36(52)13-9-34/h8-21H,4-7,22-33,54-55H2,1-3H3,(H2,56,68)(H,58,74)(H2,57,60,75)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154541 (N-allyl-2-(4-(tert-butyl)phenyl)-6-(p-tolyl)-1-tos...) Show SMILES Cc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C)C(=O)NCC=C |c:10| Show InChI InChI=1S/C33H38N2O3S/c1-7-22-34-32(36)29-20-21-30(25-12-8-23(2)9-13-25)35(39(37,38)28-18-10-24(3)11-19-28)31(29)26-14-16-27(17-15-26)33(4,5)6/h7-20,30-31H,1,21-22H2,2-6H3,(H,34,36)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154543 (N-((2-(4-(tert-butyl)phenyl)-6-(p-tolyl)-1-tosyl-1...) Show SMILES Cc1ccc(cc1)C1CC=C(CNC2CC2)C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C |t:10| Show InChI InChI=1S/C33H40N2O2S/c1-23-6-10-25(11-7-23)31-21-14-27(22-34-29-17-18-29)32(26-12-15-28(16-13-26)33(3,4)5)35(31)38(36,37)30-19-8-24(2)9-20-30/h6-16,19-20,29,31-32,34H,17-18,21-22H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154533 (2-(3-chlorophenyl)-1-(4-methylbenzenesulfonyl)-6-(...) Show SMILES Cc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1cccc(Cl)c1)C(O)=O |c:10| Show InChI InChI=1S/C26H24ClNO4S/c1-17-6-10-19(11-7-17)24-15-14-23(26(29)30)25(20-4-3-5-21(27)16-20)28(24)33(31,32)22-12-8-18(2)9-13-22/h3-14,16,24-25H,15H2,1-2H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154538 (2-(4-(tert-butyl)phenyl)-N-cyclopropyl-6-(p-tolyl)...) Show SMILES Cc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C)C(=O)NC1CC1 |c:10| Show InChI InChI=1S/C33H38N2O3S/c1-22-6-10-24(11-7-22)30-21-20-29(32(36)34-27-16-17-27)31(25-12-14-26(15-13-25)33(3,4)5)35(30)39(37,38)28-18-8-23(2)9-19-28/h6-15,18-20,27,30-31H,16-17,21H2,1-5H3,(H,34,36)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154532 (2-(3-chlorophenyl)-6-(4-ethylphenyl)-1-(4-methylbe...) Show SMILES CCc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1cccc(Cl)c1)C(O)=O |c:11| Show InChI InChI=1S/C27H26ClNO4S/c1-3-19-9-11-20(12-10-19)25-16-15-24(27(30)31)26(21-5-4-6-22(28)17-21)29(25)34(32,33)23-13-7-18(2)8-14-23/h4-15,17,25-26H,3,16H2,1-2H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154544 (Methyl-2-(4-(tert-butyl)phenyl)-6-(p-tolyl)-1-tosy...) Show SMILES COC(=O)C1=CCC(N(C1c1ccc(cc1)C(C)(C)C)S(=O)(=O)c1ccc(C)cc1)c1ccc(C)cc1 |t:4| Show InChI InChI=1S/C31H35NO4S/c1-21-7-11-23(12-8-21)28-20-19-27(30(33)36-6)29(24-13-15-25(16-14-24)31(3,4)5)32(28)37(34,35)26-17-9-22(2)10-18-26/h7-19,28-29H,20H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154539 (2-(4-(tert-butyl)phenyl)-N-cyclohexyl-6-(p-tolyl)-...) Show SMILES Cc1ccc(cc1)C1CC=C(C(N1S(=O)(=O)c1ccc(C)cc1)c1ccc(cc1)C(C)(C)C)C(=O)NC1CCCCC1 |c:10| Show InChI InChI=1S/C36H44N2O3S/c1-25-11-15-27(16-12-25)33-24-23-32(35(39)37-30-9-7-6-8-10-30)34(28-17-19-29(20-18-28)36(3,4)5)38(33)42(40,41)31-21-13-26(2)14-22-31/h11-23,30,33-34H,6-10,24H2,1-5H3,(H,37,39)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Mus musculus (Mouse))	BDBM154537 (2-(4-(tert-butyl)phenyl)-N-methyl-6-(p-tolyl)-1-to...) Show SMILES CNC(=O)C1=CCC(N(C1c1ccc(cc1)C(C)(C)C)S(=O)(=O)c1ccc(C)cc1)c1ccc(C)cc1 |t:4| Show InChI InChI=1S/C31H36N2O3S/c1-21-7-11-23(12-8-21)28-20-19-27(30(34)32-6)29(24-13-15-25(16-14-24)31(3,4)5)33(28)37(35,36)26-17-9-22(2)10-18-26/h7-19,28-29H,20H2,1-6H3,(H,32,34)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
University of California, Berkeley					Assay Description For in vitro experiments, proteomes were diluted to 1 mg/mL in PBS (pH 7.5, 50 μL total reaction volume), doped with 1 μM recombinant PAFAH...				ACS Chem Biol 10: 925-32 (2015) Article DOI: 10.1021/cb500893q BindingDB Entry DOI: 10.7270/Q2CJ8C6T
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188237 (CHEMBL3828744) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)c1ccc(OC)cc1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)CCOC)C(=O)CN(C)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C68H84BrClN18O18S/c1-80(56(91)40-88-68(102)106-66(78-88)53-27-26-52(107-53)45-14-20-48(69)21-15-45)37-60(95)84(75-55(90)28-34-103-2)42-61(96)86(77-64(99)46-16-22-49(70)23-17-46)43-63(98)87(79-67(101)74-50-12-6-5-7-13-50)44-62(97)85(76-65(100)47-18-24-51(105-4)25-19-47)41-59(94)83(33-35-104-3)39-58(93)82(32-11-9-30-72)38-57(92)81(36-54(73)89)31-10-8-29-71/h5-7,12-27H,8-11,28-44,71-72H2,1-4H3,(H2,73,89)(H,75,90)(H,76,100)(H,77,99)(H2,74,79,101)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188236 (CHEMBL3827742) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(Cc1ccc2OCOc2c1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)CCOC)C(=O)CN(C)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C68H83BrClN17O18S/c1-79(57(90)40-87-68(100)105-66(77-87)54-24-23-53(106-54)46-14-18-48(69)19-15-46)36-62(95)84(75-56(89)25-31-101-2)42-63(96)85(76-65(98)47-16-20-49(70)21-17-47)43-64(97)86(78-67(99)74-50-11-5-4-6-12-50)41-61(94)83(34-45-13-22-51-52(33-45)104-44-103-51)39-60(93)82(30-32-102-3)38-59(92)81(29-10-8-27-72)37-58(91)80(35-55(73)88)28-9-7-26-71/h4-6,11-24,33H,7-10,25-32,34-44,71-72H2,1-3H3,(H2,73,88)(H,75,89)(H,76,98)(H2,74,78,99)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188241 (CHEMBL3828121) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CNNC(=O)c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C48H61BrClN13O10S/c1-73-26-25-61(30-43(67)60(24-8-6-22-52)29-42(66)59(28-40(53)64)23-7-5-21-51)44(68)31-63(58-48(72)55-37-9-3-2-4-10-37)45(69)32-62(57-46(70)34-13-17-36(50)18-14-34)41(65)27-54-56-47(71)39-20-19-38(74-39)33-11-15-35(49)16-12-33/h2-4,9-20,54H,5-8,21-32,51-52H2,1H3,(H2,53,64)(H,56,71)(H,57,70)(H2,55,58,72)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188241 (CHEMBL3828121) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CNNC(=O)c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C48H61BrClN13O10S/c1-73-26-25-61(30-43(67)60(24-8-6-22-52)29-42(66)59(28-40(53)64)23-7-5-21-51)44(68)31-63(58-48(72)55-37-9-3-2-4-10-37)45(69)32-62(57-46(70)34-13-17-36(50)18-14-34)41(65)27-54-56-47(71)39-20-19-38(74-39)33-11-15-35(49)16-12-33/h2-4,9-20,54H,5-8,21-32,51-52H2,1H3,(H2,53,64)(H,56,71)(H,57,70)(H2,55,58,72)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188243 (CHEMBL3828611) Show SMILES NC(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C14H10BrN3O3S/c15-9-3-1-8(2-4-9)10-5-6-11(22-10)13-17-18(7-12(16)19)14(20)21-13/h1-6H,7H2,(H2,16,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188237 (CHEMBL3828744) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(NC(=O)c1ccc(OC)cc1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)CCOC)C(=O)CN(C)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C68H84BrClN18O18S/c1-80(56(91)40-88-68(102)106-66(78-88)53-27-26-52(107-53)45-14-20-48(69)21-15-45)37-60(95)84(75-55(90)28-34-103-2)42-61(96)86(77-64(99)46-16-22-49(70)23-17-46)43-63(98)87(79-67(101)74-50-12-6-5-7-13-50)44-62(97)85(76-65(100)47-18-24-51(105-4)25-19-47)41-59(94)83(33-35-104-3)39-58(93)82(32-11-9-30-72)38-57(92)81(36-54(73)89)31-10-8-29-71/h5-7,12-27H,8-11,28-44,71-72H2,1-4H3,(H2,73,89)(H,75,90)(H,76,100)(H,77,99)(H2,74,79,101)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188239 (CHEMBL3827161) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(Cc1ccc2OCOc2c1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)CCOC)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C65H78BrClN16O17S/c1-96-30-24-54(85)72-80(61(92)41-83-65(95)100-63(74-83)52-23-22-51(101-52)44-13-17-46(66)18-14-44)39-59(90)81(73-62(93)45-15-19-47(67)20-16-45)40-60(91)82(75-64(94)71-48-10-4-3-5-11-48)38-58(89)79(33-43-12-21-49-50(32-43)99-42-98-49)37-57(88)78(29-31-97-2)36-56(87)77(28-9-7-26-69)35-55(86)76(34-53(70)84)27-8-6-25-68/h3-5,10-23,32H,6-9,24-31,33-42,68-69H2,1-2H3,(H2,70,84)(H,72,85)(H,73,93)(H2,71,75,94)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase IB subunit alpha2 (Homo sapiens (Human))	BDBM50188236 (CHEMBL3827742) Show SMILES COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(Cc1ccc2OCOc2c1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)CCOC)C(=O)CN(C)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1 Show InChI InChI=1S/C68H83BrClN17O18S/c1-79(57(90)40-87-68(100)105-66(77-87)54-24-23-53(106-54)46-14-18-48(69)19-15-46)36-62(95)84(75-56(89)25-31-101-2)42-63(96)85(76-65(98)47-16-20-49(70)21-17-47)43-64(97)86(78-67(99)74-50-11-5-4-6-12-50)41-61(94)83(34-45-13-22-51-52(33-45)104-44-103-51)39-60(93)82(30-32-102-3)38-59(92)81(29-10-8-27-72)37-58(91)80(35-55(73)88)28-9-7-26-71/h4-6,11-24,33H,7-10,25-32,34-44,71-72H2,1-3H3,(H2,73,88)(H,75,89)(H,76,98)(H2,74,78,99)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.61E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shiv Nadar University Curated by ChEMBL					Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay				Bioorg Med Chem 24: 3953-3963 (2016) Article DOI: 10.1016/j.bmc.2016.04.047 BindingDB Entry DOI: 10.7270/Q2668G45
					More data for this Ligand-Target Pair