Compile Data Set for Download or QSAR

Found 165 hits Enz. Inhib. hit(s) with Target = 'Proprotein convertase subtilisin/kexin type 6'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264960 (CHEMBL4089819) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H91N17O8/c1-28(2)24-38(62-32(9)69)46(73)66-40(26-30(5)6)48(75)67-39(25-29(3)4)47(74)64-36(15-12-22-59-50(55)56)44(71)63-37(16-13-23-60-51(57)58)45(72)68-41(31(7)8)49(76)65-35(14-10-11-21-52)43(70)61-27-33-17-19-34(20-18-33)42(53)54/h17-20,28-31,35-41H,10-16,21-27,52H2,1-9H3,(H3,53,54)(H,61,70)(H,62,69)(H,63,71)(H,64,74)(H,65,76)(H,66,73)(H,67,75)(H,68,72)(H4,55,56,59)(H4,57,58,60)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264892 (CHEMBL4065072) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H91N15O8/c1-29(2)25-39(64-49(73)41(27-31(5)6)65-48(72)40(26-30(3)4)63-45(69)37(60-33(9)67)16-11-13-23-53)47(71)61-38(17-14-24-58-51(56)57)46(70)66-42(32(7)8)50(74)62-36(15-10-12-22-52)44(68)59-28-34-18-20-35(21-19-34)43(54)55/h18-21,29-32,36-42H,10-17,22-28,52-53H2,1-9H3,(H3,54,55)(H,59,68)(H,60,67)(H,61,71)(H,62,74)(H,63,69)(H,64,73)(H,65,72)(H,66,70)(H4,56,57,58)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50399749 (CHEMBL2179430) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O |r| Show InChI InChI=1S/C39H77N17O8/c1-21(2)19-24(41)31(58)56-29(20-22(3)4)35(62)54-27(13-9-17-49-38(44)45)33(60)53-26(12-8-16-48-37(42)43)32(59)51-23(5)30(57)52-25(11-6-7-15-40)34(61)55-28(36(63)64)14-10-18-50-39(46)47/h21-29H,6-20,40-41H2,1-5H3,(H,51,59)(H,52,57)(H,53,60)(H,54,62)(H,55,61)(H,56,58)(H,63,64)(H4,42,43,48)(H4,44,45,49)(H4,46,47,50)/t23-,24-,25-,26-,27-,28-,29-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PACE4 expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50399753 (CHEMBL2179835) Show SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O |r| Show InChI InChI=1S/C37H74N18O9/c1-20(40)28(57)50-22(10-3-5-15-38)29(58)51-24(12-7-17-47-35(41)42)30(59)52-25(13-8-18-48-36(43)44)32(61)55-27(21(2)56)33(62)53-23(11-4-6-16-39)31(60)54-26(34(63)64)14-9-19-49-37(45)46/h20-27,56H,3-19,38-40H2,1-2H3,(H,50,57)(H,51,58)(H,52,59)(H,53,62)(H,54,60)(H,55,61)(H,63,64)(H4,41,42,47)(H4,43,44,48)(H4,45,46,49)/t20-,21+,22-,23-,24-,25-,26-,27-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PACE4 expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265119 (CHEMBL4091099) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H91N17O8/c1-28(2)24-38(62-32(9)69)46(73)63-36(15-12-22-59-50(55)56)44(71)66-40(26-30(5)6)48(75)67-39(25-29(3)4)47(74)64-37(16-13-23-60-51(57)58)45(72)68-41(31(7)8)49(76)65-35(14-10-11-21-52)43(70)61-27-33-17-19-34(20-18-33)42(53)54/h17-20,28-31,35-41H,10-16,21-27,52H2,1-9H3,(H3,53,54)(H,61,70)(H,62,69)(H,63,73)(H,64,74)(H,65,76)(H,66,71)(H,67,75)(H,68,72)(H4,55,56,59)(H4,57,58,60)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264931 (CHEMBL4084457) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H86N16O8/c1-28(2)21-38(61-32(9)68)46(71)64-39(22-29(3)4)47(72)65-40(23-30(5)6)48(73)66-41(24-35-26-57-27-60-35)49(74)62-37(14-12-20-58-51(55)56)45(70)67-42(31(7)8)50(75)63-36(13-10-11-19-52)44(69)59-25-33-15-17-34(18-16-33)43(53)54/h15-18,26-31,36-42H,10-14,19-25,52H2,1-9H3,(H3,53,54)(H,57,60)(H,59,69)(H,61,68)(H,62,74)(H,63,75)(H,64,71)(H,65,72)(H,66,73)(H,67,70)(H4,55,56,58)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265083 (CHEMBL4100996) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H91N15O8/c1-29(2)25-39(60-33(9)67)47(71)61-37(16-11-13-23-53)45(69)64-41(27-31(5)6)49(73)65-40(26-30(3)4)48(72)62-38(17-14-24-58-51(56)57)46(70)66-42(32(7)8)50(74)63-36(15-10-12-22-52)44(68)59-28-34-18-20-35(21-19-34)43(54)55/h18-21,29-32,36-42H,10-17,22-28,52-53H2,1-9H3,(H3,54,55)(H,59,68)(H,60,67)(H,61,71)(H,62,72)(H,63,74)(H,64,69)(H,65,73)(H,66,70)(H4,56,57,58)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50303774 (CHEMBL566340 | phenylacetyl-Arg-Val-Arg-4-amidinob...) Show SMILES [#6]-[#6](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r| Show InChI InChI=1S/C33H50N12O4/c1-20(2)27(45-30(48)25(11-7-17-41-33(38)39)43-26(46)18-21-8-4-3-5-9-21)31(49)44-24(10-6-16-40-32(36)37)29(47)42-19-22-12-14-23(15-13-22)28(34)35/h3-5,8-9,12-15,20,24-25,27H,6-7,10-11,16-19H2,1-2H3,(H3,34,35)(H,42,47)(H,43,46)(H,44,49)(H,45,48)(H4,36,37,40)(H4,38,39,41)/t24-,25-,27-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human PACE4 expressed in Drosophila schneider 2 cells by fluorescence assay				J Med Chem 53: 1067-75 (2010) Article DOI: 10.1021/jm9012455 BindingDB Entry DOI: 10.7270/Q2DN455Q
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265384 (CHEMBL4104777) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H91N17O8/c1-28(2)24-38(66-48(75)40(26-30(5)6)67-47(74)39(25-29(3)4)65-44(71)36(62-32(9)69)15-12-22-59-50(55)56)46(73)63-37(16-13-23-60-51(57)58)45(72)68-41(31(7)8)49(76)64-35(14-10-11-21-52)43(70)61-27-33-17-19-34(20-18-33)42(53)54/h17-20,28-31,35-41H,10-16,21-27,52H2,1-9H3,(H3,53,54)(H,61,70)(H,62,69)(H,63,73)(H,64,76)(H,65,71)(H,66,75)(H,67,74)(H,68,72)(H4,55,56,59)(H4,57,58,60)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265344 (CHEMBL4070237) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H91N17O8/c1-28(2)24-38(62-32(9)69)46(73)67-40(26-30(5)6)48(75)63-36(15-12-22-59-50(55)56)44(71)66-39(25-29(3)4)47(74)64-37(16-13-23-60-51(57)58)45(72)68-41(31(7)8)49(76)65-35(14-10-11-21-52)43(70)61-27-33-17-19-34(20-18-33)42(53)54/h17-20,28-31,35-41H,10-16,21-27,52H2,1-9H3,(H3,53,54)(H,61,70)(H,62,69)(H,63,75)(H,64,74)(H,65,76)(H,66,71)(H,67,73)(H,68,72)(H4,55,56,59)(H4,57,58,60)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265091 (CHEMBL4083310) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H86N14O8/c1-28(2)24-37(61-46(69)38(25-29(3)4)62-47(70)40-16-13-23-64(40)49(72)39(26-30(5)6)58-32(9)65)45(68)59-36(15-12-22-56-50(54)55)44(67)63-41(31(7)8)48(71)60-35(14-10-11-21-51)43(66)57-27-33-17-19-34(20-18-33)42(52)53/h17-20,28-31,35-41H,10-16,21-27,51H2,1-9H3,(H3,52,53)(H,57,66)(H,58,65)(H,59,68)(H,60,71)(H,61,69)(H,62,70)(H,63,67)(H4,54,55,56)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265130 (CHEMBL4064275) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C49H86N14O9/c1-26(2)22-36(57-31(10)65)46(70)63-40(30(9)64)48(72)61-38(24-28(5)6)45(69)60-37(23-27(3)4)44(68)58-35(15-13-21-55-49(53)54)43(67)62-39(29(7)8)47(71)59-34(14-11-12-20-50)42(66)56-25-32-16-18-33(19-17-32)41(51)52/h16-19,26-30,34-40,64H,11-15,20-25,50H2,1-10H3,(H3,51,52)(H,56,66)(H,57,65)(H,58,68)(H,59,71)(H,60,69)(H,61,72)(H,62,67)(H,63,70)(H4,53,54,55)/t30-,34+,35+,36+,37+,38+,39+,40+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50399754 (CHEMBL2179836) Show SMILES [#7]-[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O |r| Show InChI InChI=1S/C37H69N15O13/c38-15-3-1-7-21(47-29(58)20(40)11-13-27(54)55)30(59)50-24(12-14-28(56)57)33(62)48-23(9-5-17-45-36(41)42)32(61)52-26(19-53)34(63)49-22(8-2-4-16-39)31(60)51-25(35(64)65)10-6-18-46-37(43)44/h20-26,53H,1-19,38-40H2,(H,47,58)(H,48,62)(H,49,63)(H,50,59)(H,51,60)(H,52,61)(H,54,55)(H,56,57)(H,64,65)(H4,41,42,45)(H4,43,44,46)/t20-,21-,22-,23-,24-,25-,26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PACE4 expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50399752 (CHEMBL2179429) Show SMILES [#6]-[#6](-[#6])-[#6@H](-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O |r| Show InChI InChI=1S/C39H78N16O9/c1-22(2)29(43)35(61)52-25(13-5-8-18-41)32(58)50-24(12-4-7-17-40)31(57)51-27(15-10-20-48-38(44)45)34(60)55-30(23(3)56)36(62)53-26(14-6-9-19-42)33(59)54-28(37(63)64)16-11-21-49-39(46)47/h22-30,56H,4-21,40-43H2,1-3H3,(H,50,58)(H,51,57)(H,52,61)(H,53,62)(H,54,59)(H,55,60)(H,63,64)(H4,44,45,48)(H4,46,47,49)/t23-,24+,25+,26+,27+,28+,29+,30+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PACE4 expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265145 (CHEMBL4073661) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H86N16O8/c1-28(2)21-38(64-47(72)39(22-29(3)4)65-48(73)40(23-30(5)6)66-49(74)41(61-32(9)68)24-35-26-57-27-60-35)46(71)62-37(14-12-20-58-51(55)56)45(70)67-42(31(7)8)50(75)63-36(13-10-11-19-52)44(69)59-25-33-15-17-34(18-16-33)43(53)54/h15-18,26-31,36-42H,10-14,19-25,52H2,1-9H3,(H3,53,54)(H,57,60)(H,59,69)(H,61,68)(H,62,71)(H,63,75)(H,64,72)(H,65,73)(H,66,74)(H,67,70)(H4,55,56,58)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265141 (CHEMBL4094478) Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C48H84N14O8/c1-26(2)22-36(59-41(64)30(9)56-31(10)63)45(68)61-38(24-28(5)6)46(69)60-37(23-27(3)4)44(67)57-35(15-13-21-54-48(52)53)43(66)62-39(29(7)8)47(70)58-34(14-11-12-20-49)42(65)55-25-32-16-18-33(19-17-32)40(50)51/h16-19,26-30,34-39H,11-15,20-25,49H2,1-10H3,(H3,50,51)(H,55,65)(H,56,63)(H,57,67)(H,58,70)(H,59,64)(H,60,69)(H,61,68)(H,62,66)(H4,52,53,54)/t30-,34-,35-,36-,37-,38-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264955 (CHEMBL4099961) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C49H85N15O9/c1-26(2)21-35(58-30(9)65)44(69)61-36(22-27(3)4)45(70)62-37(23-28(5)6)46(71)63-38(24-39(51)66)47(72)59-34(14-12-20-56-49(54)55)43(68)64-40(29(7)8)48(73)60-33(13-10-11-19-50)42(67)57-25-31-15-17-32(18-16-31)41(52)53/h15-18,26-29,33-38,40H,10-14,19-25,50H2,1-9H3,(H2,51,66)(H3,52,53)(H,57,67)(H,58,65)(H,59,72)(H,60,73)(H,61,69)(H,62,70)(H,63,71)(H,64,68)(H4,54,55,56)/t33-,34-,35-,36-,37-,38-,40-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265045 (CHEMBL4097940) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H86N16O8/c1-28(2)21-38(61-32(9)68)46(71)64-40(23-30(5)6)48(73)66-41(24-35-26-57-27-60-35)49(74)65-39(22-29(3)4)47(72)62-37(14-12-20-58-51(55)56)45(70)67-42(31(7)8)50(75)63-36(13-10-11-19-52)44(69)59-25-33-15-17-34(18-16-33)43(53)54/h15-18,26-31,36-42H,10-14,19-25,52H2,1-9H3,(H3,53,54)(H,57,60)(H,59,69)(H,61,68)(H,62,72)(H,63,75)(H,64,71)(H,65,74)(H,66,73)(H,67,70)(H4,55,56,58)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265129 (CHEMBL4085824) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C48H84N14O9/c1-26(2)21-35(56-30(9)64)43(67)61-38(25-63)46(70)60-37(23-28(5)6)45(69)59-36(22-27(3)4)44(68)57-34(14-12-20-54-48(52)53)42(66)62-39(29(7)8)47(71)58-33(13-10-11-19-49)41(65)55-24-31-15-17-32(18-16-31)40(50)51/h15-18,26-29,33-39,63H,10-14,19-25,49H2,1-9H3,(H3,50,51)(H,55,65)(H,56,64)(H,57,68)(H,58,71)(H,59,69)(H,60,70)(H,61,67)(H,62,66)(H4,52,53,54)/t33-,34-,35-,36-,37-,38-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264969 (CHEMBL4096348) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C48H84N14O9/c1-26(2)21-35(56-30(9)64)43(67)59-36(22-27(3)4)44(68)60-37(23-28(5)6)45(69)61-38(25-63)46(70)57-34(14-12-20-54-48(52)53)42(66)62-39(29(7)8)47(71)58-33(13-10-11-19-49)41(65)55-24-31-15-17-32(18-16-31)40(50)51/h15-18,26-29,33-39,63H,10-14,19-25,49H2,1-9H3,(H3,50,51)(H,55,65)(H,56,64)(H,57,70)(H,58,71)(H,59,67)(H,60,68)(H,61,69)(H,62,66)(H4,52,53,54)/t33-,34-,35-,36-,37-,38-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265000 (CHEMBL4101342) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C54H88N14O9/c1-30(2)25-41(62-34(9)69)49(73)65-42(26-31(3)4)50(74)66-43(27-32(5)6)51(75)67-44(28-35-17-21-38(70)22-18-35)52(76)63-40(14-12-24-60-54(58)59)48(72)68-45(33(7)8)53(77)64-39(13-10-11-23-55)47(71)61-29-36-15-19-37(20-16-36)46(56)57/h15-22,30-33,39-45,70H,10-14,23-29,55H2,1-9H3,(H3,56,57)(H,61,71)(H,62,69)(H,63,76)(H,64,77)(H,65,73)(H,66,74)(H,67,75)(H,68,72)(H4,58,59,60)/t39-,40-,41-,42-,43-,44-,45-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264941 (CHEMBL4063327) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H91N15O8/c1-29(2)25-39(60-33(9)67)47(71)64-41(27-31(5)6)49(73)65-40(26-30(3)4)48(72)62-37(16-11-13-23-53)45(69)61-38(17-14-24-58-51(56)57)46(70)66-42(32(7)8)50(74)63-36(15-10-12-22-52)44(68)59-28-34-18-20-35(21-19-34)43(54)55/h18-21,29-32,36-42H,10-17,22-28,52-53H2,1-9H3,(H3,54,55)(H,59,68)(H,60,67)(H,61,69)(H,62,72)(H,63,74)(H,64,71)(H,65,73)(H,66,70)(H4,56,57,58)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265328 (CHEMBL4087970) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C48H84N14O8/c1-26(2)22-36(57-31(10)63)44(67)56-30(9)41(64)60-37(23-27(3)4)46(69)61-38(24-28(5)6)45(68)58-35(15-13-21-54-48(52)53)43(66)62-39(29(7)8)47(70)59-34(14-11-12-20-49)42(65)55-25-32-16-18-33(19-17-32)40(50)51/h16-19,26-30,34-39H,11-15,20-25,49H2,1-10H3,(H3,50,51)(H,55,65)(H,56,67)(H,57,63)(H,58,68)(H,59,70)(H,60,64)(H,61,69)(H,62,66)(H4,52,53,54)/t30-,34-,35-,36-,37-,38-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265331 (CHEMBL4103443) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C47H82N14O8/c1-26(2)21-35(56-30(9)62)42(65)55-25-38(63)57-36(22-27(3)4)44(67)60-37(23-28(5)6)45(68)58-34(14-12-20-53-47(51)52)43(66)61-39(29(7)8)46(69)59-33(13-10-11-19-48)41(64)54-24-31-15-17-32(18-16-31)40(49)50/h15-18,26-29,33-37,39H,10-14,19-25,48H2,1-9H3,(H3,49,50)(H,54,64)(H,55,65)(H,56,62)(H,57,63)(H,58,68)(H,59,69)(H,60,67)(H,61,66)(H4,51,52,53)/t33-,34-,35-,36-,37-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50399751 (CHEMBL2179431) Show SMILES [#6]-[#6](-[#6])-[#6@H](-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O |r| Show InChI InChI=1S/C40H80N18O8/c1-22(2)29(43)35(63)55-24(12-5-7-17-41)31(59)53-26(14-9-19-50-38(44)45)32(60)54-27(15-10-20-51-39(46)47)34(62)58-30(23(3)4)36(64)56-25(13-6-8-18-42)33(61)57-28(37(65)66)16-11-21-52-40(48)49/h22-30H,5-21,41-43H2,1-4H3,(H,53,59)(H,54,60)(H,55,63)(H,56,64)(H,57,61)(H,58,62)(H,65,66)(H4,44,45,50)(H4,46,47,51)(H4,48,49,52)/t24-,25-,26-,27-,28-,29-,30-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PACE4 expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265131 (CHEMBL4093570) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H88N14O8/c1-27(2)23-37(58-32(11)65)47(70)64-41(31(9)10)49(72)62-39(25-29(5)6)46(69)61-38(24-28(3)4)45(68)59-36(16-14-22-56-50(54)55)44(67)63-40(30(7)8)48(71)60-35(15-12-13-21-51)43(66)57-26-33-17-19-34(20-18-33)42(52)53/h17-20,27-31,35-41H,12-16,21-26,51H2,1-11H3,(H3,52,53)(H,57,66)(H,58,65)(H,59,68)(H,60,71)(H,61,69)(H,62,72)(H,63,67)(H,64,70)(H4,54,55,56)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265170 (CHEMBL4075692) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H88N14O8/c1-27(2)23-37(58-32(11)65)45(68)61-38(24-28(3)4)46(69)62-39(25-29(5)6)47(70)64-41(31(9)10)49(72)60-36(16-14-22-56-50(54)55)44(67)63-40(30(7)8)48(71)59-35(15-12-13-21-51)43(66)57-26-33-17-19-34(20-18-33)42(52)53/h17-20,27-31,35-41H,12-16,21-26,51H2,1-11H3,(H3,52,53)(H,57,66)(H,58,65)(H,59,71)(H,60,72)(H,61,68)(H,62,69)(H,63,67)(H,64,70)(H4,54,55,56)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265047 (CHEMBL4072949) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H91N15O8/c1-29(2)25-39(60-33(9)67)47(71)65-41(27-31(5)6)49(73)61-37(16-11-13-23-53)45(69)64-40(26-30(3)4)48(72)62-38(17-14-24-58-51(56)57)46(70)66-42(32(7)8)50(74)63-36(15-10-12-22-52)44(68)59-28-34-18-20-35(21-19-34)43(54)55/h18-21,29-32,36-42H,10-17,22-28,52-53H2,1-9H3,(H3,54,55)(H,59,68)(H,60,67)(H,61,73)(H,62,72)(H,63,74)(H,64,69)(H,65,71)(H,66,70)(H4,56,57,58)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50303775 ((S)-2-acetamido-N-((S)-1-((S)-1-(4-carbamimidoylbe...) Show SMILES [#6]-[#6](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r| Show InChI InChI=1S/C27H46N12O4/c1-15(2)21(39-24(42)20(37-16(3)40)7-5-13-35-27(32)33)25(43)38-19(6-4-12-34-26(30)31)23(41)36-14-17-8-10-18(11-9-17)22(28)29/h8-11,15,19-21H,4-7,12-14H2,1-3H3,(H3,28,29)(H,36,41)(H,37,40)(H,38,43)(H,39,42)(H4,30,31,34)(H4,32,33,35)/t19-,20-,21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human PACE4 expressed in Drosophila schneider 2 cells by fluorescence assay				J Med Chem 53: 1067-75 (2010) Article DOI: 10.1021/jm9012455 BindingDB Entry DOI: 10.7270/Q2DN455Q
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265048 (CHEMBL4065627) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H90N14O8/c1-12-32(10)42(65-48(71)38(24-28(2)3)59-33(11)66)50(73)63-40(26-30(6)7)47(70)62-39(25-29(4)5)46(69)60-37(17-15-23-57-51(55)56)45(68)64-41(31(8)9)49(72)61-36(16-13-14-22-52)44(67)58-27-34-18-20-35(21-19-34)43(53)54/h18-21,28-32,36-42H,12-17,22-27,52H2,1-11H3,(H3,53,54)(H,58,67)(H,59,66)(H,60,69)(H,61,72)(H,62,70)(H,63,73)(H,64,68)(H,65,71)(H4,55,56,57)/t32-,36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50466079 (CHEMBL4286124) Show SMILES CC(C)C[C@@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(nc1)C(N)=N |r| Show InChI InChI=1S/C50H89N15O8/c1-27(2)21-37(59-32(11)66)45(69)62-39(23-29(5)6)47(71)64-40(24-30(7)8)48(72)63-38(22-28(3)4)46(70)60-36(16-14-20-56-50(54)55)44(68)65-41(31(9)10)49(73)61-35(15-12-13-19-51)43(67)58-26-33-17-18-34(42(52)53)57-25-33/h17-18,25,27-31,35-41H,12-16,19-24,26,51H2,1-11H3,(H3,52,53)(H,58,67)(H,59,66)(H,60,70)(H,61,73)(H,62,69)(H,63,72)(H,64,71)(H,65,68)(H4,54,55,56)/t35-,36-,37+,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 using pGlu-Arg-Thr-Lys-Arg-AMC peptide as substrate by spectrofluorometry				J Med Chem 61: 11250-11260 (2018) Article DOI: 10.1021/acs.jmedchem.8b01381 BindingDB Entry DOI: 10.7270/Q2TQ646X
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264970 (CHEMBL4059801) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C49H86N14O9/c1-26(2)22-36(57-31(10)65)44(68)60-37(23-27(3)4)45(69)61-38(24-28(5)6)46(70)63-40(30(9)64)48(72)59-35(15-13-21-55-49(53)54)43(67)62-39(29(7)8)47(71)58-34(14-11-12-20-50)42(66)56-25-32-16-18-33(19-17-32)41(51)52/h16-19,26-30,34-40,64H,11-15,20-25,50H2,1-10H3,(H3,51,52)(H,56,66)(H,57,65)(H,58,71)(H,59,72)(H,60,68)(H,61,69)(H,62,67)(H,63,70)(H4,53,54,55)/t30-,34+,35+,36+,37+,38+,39+,40+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264999 (CHEMBL4084913) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C56H89N15O8/c1-31(2)25-43(65-35(9)72)51(75)68-44(26-32(3)4)52(76)69-45(27-33(5)6)53(77)70-46(28-38-30-63-40-16-11-10-15-39(38)40)54(78)66-42(18-14-24-62-56(60)61)50(74)71-47(34(7)8)55(79)67-41(17-12-13-23-57)49(73)64-29-36-19-21-37(22-20-36)48(58)59/h10-11,15-16,19-22,30-34,41-47,63H,12-14,17-18,23-29,57H2,1-9H3,(H3,58,59)(H,64,73)(H,65,72)(H,66,78)(H,67,79)(H,68,75)(H,69,76)(H,70,77)(H,71,74)(H4,60,61,62)/t41-,42-,43-,44-,45-,46-,47-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265092 (CHEMBL4063219) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H87N15O9/c1-27(2)23-37(59-31(9)66)46(71)61-36(19-20-40(52)67)44(69)63-39(25-29(5)6)48(73)64-38(24-28(3)4)47(72)60-35(14-12-22-57-50(55)56)45(70)65-41(30(7)8)49(74)62-34(13-10-11-21-51)43(68)58-26-32-15-17-33(18-16-32)42(53)54/h15-18,27-30,34-39,41H,10-14,19-26,51H2,1-9H3,(H2,52,67)(H3,53,54)(H,58,68)(H,59,66)(H,60,72)(H,61,71)(H,62,74)(H,63,69)(H,64,73)(H,65,70)(H4,55,56,57)/t34-,35-,36-,37-,38-,39-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265144 (CHEMBL4067772) Show SMILES CC(C)C[C@H](NC(=O)CNC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C47H82N14O8/c1-26(2)21-35(56-38(63)25-54-30(9)62)43(66)59-37(23-28(5)6)45(68)60-36(22-27(3)4)44(67)57-34(14-12-20-53-47(51)52)42(65)61-39(29(7)8)46(69)58-33(13-10-11-19-48)41(64)55-24-31-15-17-32(18-16-31)40(49)50/h15-18,26-29,33-37,39H,10-14,19-25,48H2,1-9H3,(H3,49,50)(H,54,62)(H,55,64)(H,56,63)(H,57,67)(H,58,69)(H,59,66)(H,60,68)(H,61,65)(H4,51,52,53)/t33-,34-,35-,36-,37-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264972 (CHEMBL4080551) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H87N15O9/c1-27(2)23-37(63-48(73)39(25-29(5)6)64-47(72)38(24-28(3)4)62-44(69)36(59-31(9)66)19-20-40(52)67)46(71)60-35(14-12-22-57-50(55)56)45(70)65-41(30(7)8)49(74)61-34(13-10-11-21-51)43(68)58-26-32-15-17-33(18-16-32)42(53)54/h15-18,27-30,34-39,41H,10-14,19-26,51H2,1-9H3,(H2,52,67)(H3,53,54)(H,58,68)(H,59,66)(H,60,71)(H,61,74)(H,62,69)(H,63,73)(H,64,72)(H,65,70)(H4,55,56,57)/t34-,35-,36-,37-,38-,39-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50303776 (CHEMBL568525 | N-((6S,9S,12S)-1,17-diamino-6-(4-ca...) Show SMILES [#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r| Show InChI InChI=1S/C35H62N12O4/c1-4-5-6-7-8-9-10-15-28(48)45-27(14-12-21-43-35(40)41)32(50)47-29(23(2)3)33(51)46-26(13-11-20-42-34(38)39)31(49)44-22-24-16-18-25(19-17-24)30(36)37/h16-19,23,26-27,29H,4-15,20-22H2,1-3H3,(H3,36,37)(H,44,49)(H,45,48)(H,46,51)(H,47,50)(H4,38,39,42)(H4,40,41,43)/t26-,27-,29-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of human PACE4 expressed in Drosophila schneider 2 cells by fluorescence assay				J Med Chem 53: 1067-75 (2010) Article DOI: 10.1021/jm9012455 BindingDB Entry DOI: 10.7270/Q2DN455Q
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265332 (CHEMBL4093266) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C51H86N16O8/c1-28(2)21-38(61-32(9)68)46(71)66-41(24-35-26-57-27-60-35)49(74)65-40(23-30(5)6)48(73)64-39(22-29(3)4)47(72)62-37(14-12-20-58-51(55)56)45(70)67-42(31(7)8)50(75)63-36(13-10-11-19-52)44(69)59-25-33-15-17-34(18-16-33)43(53)54/h15-18,26-31,36-42H,10-14,19-25,52H2,1-9H3,(H3,53,54)(H,57,60)(H,59,69)(H,61,68)(H,62,72)(H,63,75)(H,64,73)(H,65,74)(H,66,71)(H,67,70)(H4,55,56,58)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264971 (CHEMBL4089913) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H86N14O8/c1-28(2)24-37(60-46(69)38(25-29(3)4)61-47(70)39(26-30(5)6)62-48(71)40-16-13-23-64(40)32(9)65)45(68)58-36(15-12-22-56-50(54)55)44(67)63-41(31(7)8)49(72)59-35(14-10-11-21-51)43(66)57-27-33-17-19-34(20-18-33)42(52)53/h17-20,28-31,35-41H,10-16,21-27,51H2,1-9H3,(H3,52,53)(H,57,66)(H,58,68)(H,59,72)(H,60,69)(H,61,70)(H,62,71)(H,63,67)(H4,54,55,56)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50446944 (CHEMBL3115771) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](-[#7])=[#7] |r| Show InChI InChI=1S/C51H90N14O8/c1-28(2)23-38(59-33(11)66)46(69)62-40(25-30(5)6)48(71)64-41(26-31(7)8)49(72)63-39(24-29(3)4)47(70)60-37(16-14-22-57-51(55)56)45(68)65-42(32(9)10)50(73)61-36(15-12-13-21-52)44(67)58-27-34-17-19-35(20-18-34)43(53)54/h17-20,28-32,36-42H,12-16,21-27,52H2,1-11H3,(H3,53,54)(H,58,67)(H,59,66)(H,60,70)(H,61,73)(H,62,69)(H,63,72)(H,64,71)(H,65,68)(H4,55,56,57)/t36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Inhibition of human recombinant PACE4 expressed in drosophila schneider 2 cells using pyroGlu-Arg-Thr-Lys-Arg-AMC as substrate after 1 hr				J Med Chem 57: 98-109 (2014) Article DOI: 10.1021/jm401457n BindingDB Entry DOI: 10.7270/Q2S1840S
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50533413 (CHEMBL3126388) Show SMILES CCCCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)CCl |r| Show InChI InChI=1S/C34H66ClN11O5/c1-4-5-6-7-8-9-10-18-28(48)43-25(17-14-21-42-34(39)40)31(50)46-29(23(2)3)32(51)45-26(15-11-12-19-36)30(49)44-24(27(47)22-35)16-13-20-41-33(37)38/h23-26,29H,4-22,36H2,1-3H3,(H,43,48)(H,44,49)(H,45,51)(H,46,50)(H4,37,38,41)(H4,39,40,42)/t24-,25-,26-,29-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre Hospitalier Universitaire Vaudois (CHUV) Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal truncated human SPC4 expressed in drosophila Schneider 2 cells after 1 hr by spectrofluorometry				J Med Chem 59: 7719-37 (2016) Article DOI: 10.1021/acs.jmedchem.5b01516 BindingDB Entry DOI: 10.7270/Q2M048X4
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265162 (CHEMBL4076965) Show SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H88N14O8S/c1-28(2)24-38(58-32(9)65)46(69)62-40(26-30(5)6)48(71)63-39(25-29(3)4)47(70)60-37(20-23-73-10)44(67)59-36(15-13-22-56-50(54)55)45(68)64-41(31(7)8)49(72)61-35(14-11-12-21-51)43(66)57-27-33-16-18-34(19-17-33)42(52)53/h16-19,28-31,35-41H,11-15,20-27,51H2,1-10H3,(H3,52,53)(H,57,66)(H,58,65)(H,59,67)(H,60,70)(H,61,72)(H,62,69)(H,63,71)(H,64,68)(H4,54,55,56)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264894 (CHEMBL4063459) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C48H84N14O8/c1-26(2)22-36(57-31(10)63)45(68)61-38(24-28(5)6)46(69)60-37(23-27(3)4)44(67)56-30(9)41(64)58-35(15-13-21-54-48(52)53)43(66)62-39(29(7)8)47(70)59-34(14-11-12-20-49)42(65)55-25-32-16-18-33(19-17-32)40(50)51/h16-19,26-30,34-39H,11-15,20-25,49H2,1-10H3,(H3,50,51)(H,55,65)(H,56,67)(H,57,63)(H,58,64)(H,59,70)(H,60,69)(H,61,68)(H,62,66)(H4,52,53,54)/t30-,34-,35-,36-,37-,38-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265090 (CHEMBL4101304) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C49H85N15O9/c1-26(2)21-35(58-30(9)65)44(69)63-38(24-39(51)66)47(72)62-37(23-28(5)6)46(71)61-36(22-27(3)4)45(70)59-34(14-12-20-56-49(54)55)43(68)64-40(29(7)8)48(73)60-33(13-10-11-19-50)42(67)57-25-31-15-17-32(18-16-31)41(52)53/h15-18,26-29,33-38,40H,10-14,19-25,50H2,1-9H3,(H2,51,66)(H3,52,53)(H,57,67)(H,58,65)(H,59,70)(H,60,73)(H,61,71)(H,62,72)(H,63,69)(H,64,68)(H4,54,55,56)/t33-,34-,35-,36-,37-,38-,40-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265140 (CHEMBL4066994) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C54H88N14O9/c1-30(2)25-41(62-34(9)69)49(73)67-44(28-35-17-21-38(70)22-18-35)52(76)66-43(27-32(5)6)51(75)65-42(26-31(3)4)50(74)63-40(14-12-24-60-54(58)59)48(72)68-45(33(7)8)53(77)64-39(13-10-11-23-55)47(71)61-29-36-15-19-37(20-16-36)46(56)57/h15-22,30-33,39-45,70H,10-14,23-29,55H2,1-9H3,(H3,56,57)(H,61,71)(H,62,69)(H,63,74)(H,64,77)(H,65,75)(H,66,76)(H,67,73)(H,68,72)(H4,58,59,60)/t39-,40-,41-,42-,43-,44-,45-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265185 (CHEMBL4092088) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H86N14O8/c1-28(2)24-37(58-32(9)65)45(68)62-39(26-30(5)6)49(72)64-23-13-16-40(64)47(70)61-38(25-29(3)4)46(69)59-36(15-12-22-56-50(54)55)44(67)63-41(31(7)8)48(71)60-35(14-10-11-21-51)43(66)57-27-33-17-19-34(20-18-33)42(52)53/h17-20,28-31,35-41H,10-16,21-27,51H2,1-9H3,(H3,52,53)(H,57,66)(H,58,65)(H,59,69)(H,60,71)(H,61,70)(H,62,68)(H,63,67)(H4,54,55,56)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265302 (CHEMBL4060537) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H88N14O8/c1-27(2)23-37(58-32(11)65)45(68)61-39(25-29(5)6)47(70)64-41(31(9)10)49(72)62-38(24-28(3)4)46(69)59-36(16-14-22-56-50(54)55)44(67)63-40(30(7)8)48(71)60-35(15-12-13-21-51)43(66)57-26-33-17-19-34(20-18-33)42(52)53/h17-20,27-31,35-41H,12-16,21-26,51H2,1-11H3,(H3,52,53)(H,57,66)(H,58,65)(H,59,69)(H,60,71)(H,61,68)(H,62,72)(H,63,67)(H,64,70)(H4,54,55,56)/t35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264930 (CHEMBL4077533) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C54H88N14O8/c1-31(2)26-41(62-35(9)69)49(72)65-42(27-32(3)4)50(73)66-43(28-33(5)6)51(74)67-44(29-36-16-11-10-12-17-36)52(75)63-40(19-15-25-60-54(58)59)48(71)68-45(34(7)8)53(76)64-39(18-13-14-24-55)47(70)61-30-37-20-22-38(23-21-37)46(56)57/h10-12,16-17,20-23,31-34,39-45H,13-15,18-19,24-30,55H2,1-9H3,(H3,56,57)(H,61,70)(H,62,69)(H,63,75)(H,64,76)(H,65,72)(H,66,73)(H,67,74)(H,68,71)(H4,58,59,60)/t39-,40-,41-,42-,43-,44-,45-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50264994 (CHEMBL4097058) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C49H86N14O9/c1-26(2)22-36(60-45(69)37(23-27(3)4)61-46(70)38(24-28(5)6)62-48(72)40(30(9)64)57-31(10)65)44(68)58-35(15-13-21-55-49(53)54)43(67)63-39(29(7)8)47(71)59-34(14-11-12-20-50)42(66)56-25-32-16-18-33(19-17-32)41(51)52/h16-19,26-30,34-40,64H,11-15,20-25,50H2,1-10H3,(H3,51,52)(H,56,66)(H,57,65)(H,58,68)(H,59,71)(H,60,69)(H,61,70)(H,62,72)(H,63,67)(H4,53,54,55)/t30-,34+,35+,36+,37+,38+,39+,40+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair
Proprotein convertase subtilisin/kexin type 6 (Homo sapiens (Human))	BDBM50265186 (CHEMBL4091172) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N |r| Show InChI InChI=1S/C50H87N15O9/c1-27(2)23-37(59-31(9)66)46(71)64-39(25-29(5)6)48(73)61-36(19-20-40(52)67)44(69)63-38(24-28(3)4)47(72)60-35(14-12-22-57-50(55)56)45(70)65-41(30(7)8)49(74)62-34(13-10-11-21-51)43(68)58-26-32-15-17-33(18-16-32)42(53)54/h15-18,27-30,34-39,41H,10-14,19-26,51H2,1-9H3,(H2,52,67)(H3,53,54)(H,58,68)(H,59,66)(H,60,72)(H,61,73)(H,62,74)(H,63,69)(H,64,71)(H,65,70)(H4,55,56,57)/t34-,35-,36-,37-,38-,39-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gdansk Curated by ChEMBL					Assay Description Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...				J Med Chem 60: 2732-2744 (2017) Article DOI: 10.1021/acs.jmedchem.6b01499 BindingDB Entry DOI: 10.7270/Q2HD7Z4F
					More data for this Ligand-Target Pair

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