Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1027-1207,A156T]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1027-1207,A156T] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM241943 (US9422333, I-23) Show SMILES CCC[C@H](NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@H](CNC(=O)C=C)NC(=O)[C@@H](NC(=O)c1cnccn1)C1CCCCC1)C(OC(=O)C(F)(F)F)C(=O)NC1CC1 |r,w:43.47| Show InChI InChI=1S/C38H51F3N8O8/c1-3-9-25(31(35(54)45-23-14-15-23)57-37(56)38(39,40)41)46-34(53)30-24-13-8-12-22(24)20-49(30)36(55)27(19-44-28(50)4-2)47-33(52)29(21-10-6-5-7-11-21)48-32(51)26-18-42-16-17-43-26/h4,16-18,21-25,27,29-31H,2-3,5-15,19-20H2,1H3,(H,44,50)(H,45,54)(H,46,53)(H,47,52)(H,48,51)/t22-,24-,25-,27-,29-,30-,31?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	985	n/a	n/a	n/a	n/a	7.5	n/a
Celgene Avilomics Research, Inc. US Patent					Assay Description The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...				US Patent US9422333 (2016) BindingDB Entry DOI: 10.7270/Q2B27T6P
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