Compile Data Set for Download or QSAR

Found 784 hits Enz. Inhib. hit(s) with Target = 'Protein-tyrosine kinase 2-beta'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286349 (US11220518, Ex. No. K7 | US11780853, Example K7 | ...) Show SMILES C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C21H28F4N8O2/c1-11-8-32(12(2)7-31(11)5)19(34)33-9-13-15(20(33,3)4)29-30-16(13)27-17-14(22)6-26-18(28-17)35-10-21(23,24)25/h6,11-12H,7-10H2,1-5H3,(H2,26,27,28,29,30)/t11-,12+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.165	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286350 (US11220518, Ex. No. K8 | US11780853, Example K8 | ...) Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C22H30F4N8O2/c1-12-8-32(6)20(2,3)10-33(12)19(35)34-9-13-15(21(34,4)5)30-31-16(13)28-17-14(23)7-27-18(29-17)36-11-22(24,25)26/h7,12H,8-11H2,1-6H3,(H2,27,28,29,30,31)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.181	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286348 (US11220518, Ex. No. K6 | US11780853, Example K6 | ...) Show SMILES COCCCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C24H34F4N8O3/c1-14-11-35(15(2)10-34(14)7-6-8-38-5)22(37)36-12-16-18(23(36,3)4)32-33-19(16)30-20-17(25)9-29-21(31-20)39-13-24(26,27)28/h9,14-15H,6-8,10-13H2,1-5H3,(H2,29,30,31,32,33)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.376	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286347 (US11220518, Ex. No. K5 | US11780853, Example K5 | ...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCCOC)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C24H37FN8O3/c1-7-36-22-26-11-18(25)21(28-22)27-20-17-14-33(24(4,5)19(17)29-30-20)23(34)32-13-15(2)31(12-16(32)3)9-8-10-35-6/h11,15-16H,7-10,12-14H2,1-6H3,(H2,26,27,28,29,30)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.683	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286345 (US11220518, Ex. No. K3 | US11780853, Example K3 | ...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.912	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286246 (5-{[(8S)-6,8-dimethyl-6,9-diazaspiro[4.5]dec-9-yl]...) Show SMILES C[C@H]1CN(C)C2(CCCC2)CN1C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.01	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286343 (N-(2-ethoxy-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)CC2C)C3(C)C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.12	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286320 (US9518060, Example J6) Show SMILES C[C@H]1CC(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.17	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286270 (US11220518, Ex. No. E2 | US11780853, Example E2 | ...) Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCCOC)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C24H37FN8O2/c1-7-19-26-11-18(25)22(27-19)28-21-17-14-33(24(4,5)20(17)29-30-21)23(34)32-13-15(2)31(12-16(32)3)9-8-10-35-6/h11,15-16H,7-10,12-14H2,1-6H3,(H2,26,27,28,29,30)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.64	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286377 (US11220518, Ex. No. L4 | US11780853, Example L4 | ...) Show SMILES CN1CCC(F)(CC1)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C Show InChI InChI=1S/C20H24F5N7O2/c1-18(2)13-11(9-32(18)16(33)19(22)4-6-31(3)7-5-19)14(30-29-13)27-15-12(21)8-26-17(28-15)34-10-20(23,24)25/h8H,4-7,9-10H2,1-3H3,(H2,26,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.71	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286310 (N-(5-fluoro-2-propylpyrimidin-4-yl)-6,6-dimethyl-5...) Show SMILES C.CCCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)NC[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C22H33FN8O.CH4/c1-7-8-16-24-10-15(23)19(26-16)27-18-14-11-31(22(5,6)17(14)28-29-18)20(32)30-12-21(3,4)25-9-13(30)2;/h10,13,25H,7-9,11-12H2,1-6H3,(H2,24,26,27,28,29);1H4/t13-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.73	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286260 (US11220518, Ex. No. B3 | US11780853, Example B3 | ...) Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H32FN9O/c1-7-23-19-24-8-15(22)18(26-19)25-17-14-11-31(21(4,5)16(14)27-28-17)20(32)30-10-12(2)29(6)9-13(30)3/h8,12-13H,7,9-11H2,1-6H3,(H3,23,24,25,26,27,28)/t12-,13+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.03	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286327 (N-[5-fluoro-2-(methoxymethyl)pyrimidin-4-yl]-6,6-d...) Show SMILES COCc1ncc(F)c(Nc2c[nH]c3c2CN(C(=O)C2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286344 (US11220518, Ex. No. K2 | US11780853, Example K2 | ...) Show SMILES CCOc1ccc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC)C[C@@H]2C)C3(C)C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.11	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286264 (US11220518, Ex. No. B6 | US11780853, Example B6 | ...) Show SMILES C[C@@H]1CN([C@@H](C)CN1C)C(=O)N1Cc2c(Nc3ccnc(n3)C#N)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C20H27N9O/c1-12-10-28(13(2)9-27(12)5)19(30)29-11-14-17(20(29,3)4)25-26-18(14)24-15-6-7-22-16(8-21)23-15/h6-7,12-13H,9-11H2,1-5H3,(H2,22,23,24,25,26)/t12-,13+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.43	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286316 (US9518060, Example J3) Show SMILES CC1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.63	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286227 (N4-(6,6-dimethyl-5-{[(2S)-2,4,5,5-tetramethylpiper...) Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C22H34FN9O/c1-8-24-19-25-9-15(23)18(27-19)26-17-14-11-32(22(5,6)16(14)28-29-17)20(33)31-12-21(3,4)30(7)10-13(31)2/h9,13H,8,10-12H2,1-7H3,(H3,24,25,26,27,28,29)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.69	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286346 (US11220518, Ex. No. K4 | US11780853, Example K4 | ...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCOC)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C23H35FN8O3/c1-7-35-21-25-10-17(24)20(27-21)26-19-16-13-32(23(4,5)18(16)28-29-19)22(33)31-12-14(2)30(8-9-34-6)11-15(31)3/h10,14-15H,7-9,11-13H2,1-6H3,(H2,25,26,27,28,29)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.33	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286244 (US11220518, Ex. No. A8 | US11780853, Example A8 | ...) Show SMILES CCNc1nccc(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C22H35N9O/c1-8-23-19-24-10-9-16(26-19)25-18-15-12-31(22(5,6)17(15)27-28-18)20(32)30-13-21(3,4)29(7)11-14(30)2/h9-10,14H,8,11-13H2,1-7H3,(H3,23,24,25,26,27,28)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.39	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286311 (US11220518, Ex. No. I2 | US11780853, Example I2 | ...) Show SMILES CC(C)c1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C23H35FN8O/c1-13(2)18-25-9-16(24)20(26-18)27-19-15-11-32(23(6,7)17(15)28-29-19)21(33)31-12-22(4,5)30(8)10-14(31)3/h9,13-14H,10-12H2,1-8H3,(H2,25,26,27,28,29)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.67	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286242 (US11220518, Ex. No. A7 | US11780853, Example A7 | ...) Show SMILES CC(C)Nc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C23H36FN9O/c1-13(2)26-20-25-9-16(24)19(28-20)27-18-15-11-33(23(6,7)17(15)29-30-18)21(34)32-12-22(4,5)31(8)10-14(32)3/h9,13-14H,10-12H2,1-8H3,(H3,25,26,27,28,29,30)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.81	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286239 (US11220518, Ex. No. A5 | US11780853, Example A5 | ...) Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(NC4CC4)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C23H34FN9O/c1-13-10-31(6)22(2,3)12-32(13)21(34)33-11-15-17(23(33,4)5)29-30-18(15)27-19-16(24)9-25-20(28-19)26-14-7-8-14/h9,13-14H,7-8,10-12H2,1-6H3,(H3,25,26,27,28,29,30)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.95	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286380 (N-(4-ethoxypyrimidin-2-yl)-6,6-dimethyl-5-{[(2S,5R...) Show SMILES CCOc1ccnc(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H32N8O2/c1-7-31-16-8-9-22-19(23-16)24-18-15-12-29(21(4,5)17(15)25-26-18)20(30)28-11-13(2)27(6)10-14(28)3/h8-9,13-14H,7,10-12H2,1-6H3,(H2,22,23,24,25,26)/t13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.24	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286257 (N2-ethyl-5-fluoro-N4-(5-{[(2S,5R)-4-(3-methoxyprop...) Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CCCOC)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C24H38FN9O2/c1-7-26-22-27-11-18(25)21(29-22)28-20-17-14-34(24(4,5)19(17)30-31-20)23(35)33-13-15(2)32(12-16(33)3)9-8-10-36-6/h11,15-16H,7-10,12-14H2,1-6H3,(H3,26,27,28,29,30,31)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.09	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286267 (N-(2-ethyl-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5-...) Show SMILES CCc1ccc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C23H34FN7O/c1-8-15-9-10-17(24)20(25-15)26-19-16-12-31(23(5,6)18(16)27-28-19)21(32)30-13-22(3,4)29(7)11-14(30)2/h9-10,14H,8,11-13H2,1-7H3,(H2,25,26,27,28)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.43	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286318 (US11220518, Ex. No. J5 | US11780853, Example J5 | ...) Show SMILES C[C@H]1CN2CCC[C@H]2CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.43	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286279 (US11220518, Ex. No. H3 | US11780853, Example H3 | ...) Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.21	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286317 (US11220518, Ex. No. J4 | US11780853, Example J4 | ...) Show SMILES C[C@H]1CN2CCC[C@@]2(C)CN1C(=O)N1Cc2c(Nc3nc(C)ccc3F)n[nH]c2C1(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.64	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286231 (US11780853, Example A2 | US9518060, Example A2) Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(ncc3F)N(C)C)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C22H34FN9O/c1-13-10-30(8)21(2,3)12-31(13)20(33)32-11-14-16(22(32,4)5)27-28-17(14)25-18-15(23)9-24-19(26-18)29(6)7/h9,13H,10-12H2,1-8H3,(H2,24,25,26,27,28)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.75	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286245 (US11220518, Ex. No. A9 | US11780853, Example A9 | ...) Show SMILES C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3ccnc(n3)N(C)C)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C22H35N9O/c1-14-11-29(8)21(2,3)13-30(14)20(32)31-12-15-17(22(31,4)5)26-27-18(15)24-16-9-10-23-19(25-16)28(6)7/h9-10,14H,11-13H2,1-8H3,(H2,23,24,25,26,27)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.73	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286273 (2-((5S)-4-{[3-[(2-ethyl-5-fluoropyrimidin-4-yl)ami...) Show SMILES C.CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)NC[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H31FN8O2.CH4/c1-5-16-24-9-15(22)19(25-16)26-18-14-11-30(21(3,4)17(14)27-28-18)20(32)29-10-13(6-7-31)23-8-12(29)2;/h9,12-13,23,31H,5-8,10-11H2,1-4H3,(H2,24,25,26,27,28);1H4/t12-,13?;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286335 (US11220518, Ex. No. J13 | US11780853, Example J13 ...) Show SMILES C[C@@H]1CN([C@@H](C)CN1C1CCOCC1)C(=O)N1Cc2c(Nc3nccc(n3)C(F)(F)F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C24H33F3N8O2/c1-14-12-34(15(2)11-33(14)16-6-9-37-10-7-16)22(36)35-13-17-19(23(35,3)4)31-32-20(17)30-21-28-8-5-18(29-21)24(25,26)27/h5,8,14-16H,6-7,9-13H2,1-4H3,(H2,28,29,30,31,32)/t14-,15+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286362 (US11220518, Ex. No. K19 | US11780853, Example K19 ...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C26H39FN8O3/c1-6-38-24-28-11-20(27)23(30-24)29-22-19-15-35(26(4,5)21(19)31-32-22)25(36)34-13-16(2)33(12-17(34)3)14-18-7-9-37-10-8-18/h11,16-18H,6-10,12-15H2,1-5H3,(H2,28,29,30,31,32)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286385 (US11220518, Ex. No. N3 | US11780853, Example N3 | ...) Show SMILES COCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C22H33FN8O3/c1-13-9-29(4)14(6-7-32)10-30(13)21(33)31-11-15-18(22(31,2)3)27-28-19(15)26-20-16(23)8-24-17(25-20)12-34-5/h8,13-14,32H,6-7,9-12H2,1-5H3,(H2,24,25,26,27,28)/t13-,14?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286384 (5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-...) Show SMILES COCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)C2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C27H40FN7O3/c1-16-12-34(13-18-6-8-38-9-7-18)17(2)10-19(16)26(36)35-14-20-23(27(35,3)4)32-33-24(20)31-25-21(28)11-29-22(30-25)15-37-5/h11,16-19H,6-10,12-15H2,1-5H3,(H2,29,30,31,32,33)/t16-,17+,19?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286365 (5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C[C@@H]2C)C2CCOCC2)C3(C)C)n1 |r| Show InChI InChI=1S/C25H37FN8O3/c1-6-37-23-27-11-19(26)22(29-23)28-21-18-14-34(25(4,5)20(18)30-31-21)24(35)33-13-15(2)32(12-16(33)3)17-7-9-36-10-8-17/h11,15-17H,6-10,12-14H2,1-5H3,(H2,27,28,29,30,31)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286368 (US11220518, Ex. No. K24 | US11780853, Example K24 ...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C22H33FN8O3/c1-6-34-20-24-9-16(23)19(26-20)25-18-15-12-31(22(3,4)17(15)27-28-18)21(33)30-11-14(7-8-32)29(5)10-13(30)2/h9,13-14,32H,6-8,10-12H2,1-5H3,(H2,24,25,26,27,28)/t13-,14?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286368 (US11220518, Ex. No. K24 | US11780853, Example K24 ...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C22H33FN8O3/c1-6-34-20-24-9-16(23)19(26-20)25-18-15-12-31(22(3,4)17(15)27-28-18)21(33)30-11-14(7-8-32)29(5)10-13(30)2/h9,13-14,32H,6-8,10-12H2,1-5H3,(H2,24,25,26,27,28)/t13-,14?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286332 (US11220518, Ex. No. J12 | US11780853, Example J12 ...) Show SMILES C[C@@H]1CN([C@@H](C)CN1C1CCOCC1)C(=O)N1Cc2c(Nc3nccc(C)n3)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C24H36N8O2/c1-15-6-9-25-22(26-15)27-21-19-14-32(24(4,5)20(19)28-29-21)23(33)31-13-16(2)30(12-17(31)3)18-7-10-34-11-8-18/h6,9,16-18H,7-8,10-14H2,1-5H3,(H2,25,26,27,28,29)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286331 (US11220518, Ex. No. J11 | US11780853, Example J11 ...) Show SMILES COc1ccnc(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C[C@@H]2C)C2CCOCC2)C3(C)C)n1 |r| Show InChI InChI=1S/C24H36N8O3/c1-15-13-31(16(2)12-30(15)17-7-10-35-11-8-17)23(33)32-14-18-20(24(32,3)4)28-29-21(18)27-22-25-9-6-19(26-22)34-5/h6,9,15-17H,7-8,10-14H2,1-5H3,(H2,25,26,27,28,29)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286330 (US11220518, Ex. No. J10 | US11780853, Example J10 ...) Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C26H39FN8O2/c1-6-21-28-11-20(27)24(29-21)30-23-19-15-35(26(4,5)22(19)31-32-23)25(36)34-13-16(2)33(12-17(34)3)14-18-7-9-37-10-8-18/h11,16-18H,6-10,12-15H2,1-5H3,(H2,28,29,30,31,32)/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286340 (US11220518, Ex. No. J15 | US11780853, Example J15 ...) Show SMILES C[C@@H]1CN([C@@H](C)CN1CC1CCOCC1)C(=O)N1Cc2c(Nc3nccc(C)n3)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C25H38N8O2/c1-16-6-9-26-23(27-16)28-22-20-15-33(25(4,5)21(20)29-30-22)24(34)32-13-17(2)31(12-18(32)3)14-19-7-10-35-11-8-19/h6,9,17-19H,7-8,10-15H2,1-5H3,(H2,26,27,28,29,30)/t17-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286251 (US11220518, Ex. No. A12 | US11780853, Example A12 ...) Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C[C@@H]2C)C2CCOCC2)C3(C)C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286248 (N4-(5-{[(2S,5R)-2,5-dimethyl-4-(tetrahydro-2H-pyra...) Show SMILES CCNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC4CCOCC4)C[C@@H]2C)C3(C)C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50341636 ((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...) Show SMILES CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3[nH]c(C)c(C(=O)N4CCN(C)CC4)c3C)c2c1 Show InChI InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	10.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sandia National Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PYK2 by ESI-MS analysis				J Med Chem 55: 1926-39 (2012) Article DOI: 10.1021/jm200979x BindingDB Entry DOI: 10.7270/Q2R212DQ
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286269 (N-(2-ethyl-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5-...) Show SMILES CCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H31FN8O/c1-7-16-23-8-15(22)19(24-16)25-18-14-11-30(21(4,5)17(14)26-27-18)20(31)29-10-12(2)28(6)9-13(29)3/h8,12-13H,7,9-11H2,1-6H3,(H2,23,24,25,26,27)/t12-,13+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286241 (US11220518, Ex. No. A6 | US11780853, Example A6 | ...) Show SMILES CNc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H32FN9O/c1-12-9-29(7)20(2,3)11-30(12)19(32)31-10-13-15(21(31,4)5)27-28-16(13)25-17-14(22)8-24-18(23-6)26-17/h8,12H,9-11H2,1-7H3,(H3,23,24,25,26,27,28)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10.8	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286342 (US11220518, Ex. No. J16 | US11780853, Example J16 ...) Show SMILES C[C@@H]1CN([C@@H](C)CN1CC1CCOCC1)C(=O)N1Cc2c(Nc3nc(C)cc(C)n3)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C26H40N8O2/c1-16-11-17(2)28-24(27-16)29-23-21-15-34(26(5,6)22(21)30-31-23)25(35)33-13-18(3)32(12-19(33)4)14-20-7-9-36-10-8-20/h11,18-20H,7-10,12-15H2,1-6H3,(H2,27,28,29,30,31)/t18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.1	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286357 (US11220518, Ex. No. K15 | US11780853, Example K15 ...) Show SMILES CCOc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@]4(C)CCCN4C[C@@H]2C)C3(C)C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.2	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286351 (US9518060, Example K9) Show SMILES C.C[C@H]1CN(C)C(C)(C)CN1C(=O)N1Cc2c(Nc3nc(OCCCO)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C23H35FN8O3.CH4/c1-14-11-30(6)22(2,3)13-31(14)21(34)32-12-15-17(23(32,4)5)28-29-18(15)26-19-16(24)10-25-20(27-19)35-9-7-8-33;/h10,14,33H,7-9,11-13H2,1-6H3,(H2,25,26,27,28,29);1H4/t14-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12.8	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 784 total )  |  Next  |  Last  >>

Jump to: