Found 13 hits Enz. Inhib. hit(s) with Target = 'Protein tyrosine phosphatase receptor type C-associated protein' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50131866
(7-Thiophosphonomethyl-naphthalene-1-carboxylic aci...)Show InChI InChI=1S/C12H11O4PS/c13-12(14)10-3-1-2-9-5-4-8(6-11(9)10)7-17(15,16)18/h1-6H,7H2,(H,13,14)(H2,15,16,18) | KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Utah State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against Tyrosine phosphatase from Yersinia (Yop protein) |
J Med Chem 46: 3703-8 (2003)
Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50131869
(CHEMBL122577 | Methyl-phosphonothioic acid)Show InChI InChI=1S/CH5O2PS/c1-4(2,3)5/h1H3,(H2,2,3,5) | KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 7.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Utah State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against Tyrosine phosphatase from Yersinia (Yop protein) |
J Med Chem 46: 3703-8 (2003)
Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50131863
(CHEMBL331460 | Phenylsulfanylmethyl-phosphonothioi...)Show InChI InChI=1S/C7H9O2PS2/c8-10(9,11)6-12-7-4-2-1-3-5-7/h1-5H,6H2,(H2,8,9,11) | KEGG
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.58E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Utah State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against Tyrosine phosphatase from Yersinia (Yop protein) |
J Med Chem 46: 3703-8 (2003)
Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50131867
(6-Thiophosphono-hexanoic acid | CHEMBL123990)Show InChI InChI=1S/C6H13O4PS/c7-6(8)4-2-1-3-5-11(9,10)12/h1-5H2,(H,7,8)(H2,9,10,12) | KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 2.90E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Utah State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against Tyrosine phosphatase from Yersinia (Yop protein) |
J Med Chem 46: 3703-8 (2003)
Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50131862
(CHEMBL122938 | methylphosphonic acid)Show InChI InChI=1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4) | KEGG
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| Article
PubMed
| 3.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Utah State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against Tyrosine phosphatase from Yersinia (Yop protein) |
J Med Chem 46: 3703-8 (2003)
Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50131860
(6-Phosphono-hexanoic acid | CHEMBL122539)Show InChI InChI=1S/C6H13O5P/c7-6(8)4-2-1-3-5-12(9,10)11/h1-5H2,(H,7,8)(H2,9,10,11) | KEGG
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| Article
PubMed
| 4.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Utah State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against Tyrosine phosphatase from Yersinia (Yop protein) |
J Med Chem 46: 3703-8 (2003)
Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50212333
(5-[3'-(1-adamantyl)-2-chloro-4'-hydroxy-4-biphenyl...)Show SMILES Oc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc(cc1Cl)-c1nnn[nH]1 |TLB:6:7:10:14.13.12,THB:8:9:12:16.7.15,8:7:10.9.14:12,15:7:10:14.13.12,15:13:10:16.8.7| Show InChI InChI=1S/C23H23ClN4O/c24-20-9-17(22-25-27-28-26-22)1-3-18(20)16-2-4-21(29)19(8-16)23-10-13-5-14(11-23)7-15(6-13)12-23/h1-4,8-9,13-15,29H,5-7,10-12H2,(H,25,26,27,28) | KEGG
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research
Curated by ChEMBL
| Assay Description
Inhibition of CD45 PTP by fluorescence spectrometry |
J Med Chem 50: 2622-39 (2007)
Article DOI: 10.1021/jm0613323
BindingDB Entry DOI: 10.7270/Q2XS5V3H |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50212331
(5-[1-(3'-adamantan-1-yl-2-chloro-4'-hydroxy-biphen...)Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(c(Cl)c1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2 |w:7.8,t:1,TLB:20:22:25:29.28.27,THB:23:24:27:31.22.30,23:22:25.24.29:27,30:22:25:29.28.27,30:28:25:31.23.22| Show InChI InChI=1S/C26H24ClNO3S/c27-21-8-14(9-23-24(30)28-25(31)32-23)1-3-19(21)18-2-4-22(29)20(10-18)26-11-15-5-16(12-26)7-17(6-15)13-26/h1-4,8-10,15-17,29H,5-7,11-13H2,(H,28,30,31) | KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Institute for Medical Research
Curated by ChEMBL
| Assay Description
Inhibition of CD45 PTP by fluorescence spectrometry |
J Med Chem 50: 2622-39 (2007)
Article DOI: 10.1021/jm0613323
BindingDB Entry DOI: 10.7270/Q2XS5V3H |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50083572
((S)-1,2-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[d...)Show InChI InChI=1S/C18H19NO2/c1-20-15-10-12-7-8-19-14-9-11-5-3-4-6-13(11)17(16(12)14)18(15)21-2/h3-6,10,14,19H,7-9H2,1-2H3/t14-/m0/s1 | KEGG
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| Article
| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory activity against recombinant CD45 protein tyrosine phosphatase |
Bioorg Med Chem Lett 5: 1519-1522 (1995)
Article DOI: 10.1016/0960-894X(95)00250-W
BindingDB Entry DOI: 10.7270/Q2V69K2S |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50202322
((-)-anonaine | (R)-6,7,7a,8-tetrahydro-5H-benzo[g]...)Show InChI InChI=1S/C17H15NO2/c1-2-4-12-10(3-1)7-13-15-11(5-6-18-13)8-14-17(16(12)15)20-9-19-14/h1-4,8,13,18H,5-7,9H2/t13-/m1/s1 | KEGG
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PC sid
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| Article
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory activity against recombinant CD45 protein tyrosine phosphatase |
Bioorg Med Chem Lett 5: 1519-1522 (1995)
Article DOI: 10.1016/0960-894X(95)00250-W
BindingDB Entry DOI: 10.7270/Q2V69K2S |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50197829
((S)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrah...)Show SMILES COc1cc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(-c2cc1OC)c34 |r| Show InChI InChI=1S/C21H25NO4/c1-22-7-6-12-9-18(25-4)21(26-5)20-14-11-17(24-3)16(23-2)10-13(14)8-15(22)19(12)20/h9-11,15H,6-8H2,1-5H3/t15-/m0/s1 | KEGG
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| Article
| n/a | n/a | 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory activity against recombinant CD45 protein tyrosine phosphatase |
Bioorg Med Chem Lett 5: 1519-1522 (1995)
Article DOI: 10.1016/0960-894X(95)00250-W
BindingDB Entry DOI: 10.7270/Q2V69K2S |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50284797
(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)Show InChI InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 | KEGG
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| Article
| n/a | n/a | 1.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory activity against recombinant CD45 protein tyrosine phosphatase |
Bioorg Med Chem Lett 5: 1519-1522 (1995)
Article DOI: 10.1016/0960-894X(95)00250-W
BindingDB Entry DOI: 10.7270/Q2V69K2S |
More data for this
Ligand-Target Pair | |
Protein tyrosine phosphatase receptor type C-associated protein
(Homo sapiens (Human)) | BDBM50202301
(CHEMBL37736 | Liriodenine | hiriodenine)Show InChI InChI=1S/C17H9NO3/c19-16-11-4-2-1-3-10(11)14-13-9(5-6-18-15(13)16)7-12-17(14)21-8-20-12/h1-7H,8H2 | KEGG
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| Article
| n/a | n/a | 1.82E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory activity against recombinant CD45 protein tyrosine phosphatase |
Bioorg Med Chem Lett 5: 1519-1522 (1995)
Article DOI: 10.1016/0960-894X(95)00250-W
BindingDB Entry DOI: 10.7270/Q2V69K2S |
More data for this
Ligand-Target Pair | |
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