Compile Data Set for Download or QSAR

Found 25 hits Enz. Inhib. hit(s) with Target = 'Tubulin--tyrosine ligase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM18129 ((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(O)=O Show InChI InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	2.50E+4	-27.3	n/a	n/a	n/a	n/a	n/a	6.8	37
Binghamton University					Assay Description Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).				ACS Chem Biol 5: 777-85 (2010) Article DOI: 10.1021/cb100060v BindingDB Entry DOI: 10.7270/Q25H7DM1
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM36556 (3-Azidotyrosine) Show SMILES NC(Cc1ccc(O)c(c1)N=[N]#N)C(O)=O Show InChI InChI=1S/C9H10N4O3/c10-6(9(15)16)3-5-1-2-8(14)7(4-5)12-13-11/h1-2,4,6,14H,3,10H2,(H,15,16)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.00E+5	-22.0	n/a	n/a	n/a	n/a	n/a	6.8	37
Binghamton University					Assay Description Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).				ACS Chem Biol 5: 777-85 (2010) Article DOI: 10.1021/cb100060v BindingDB Entry DOI: 10.7270/Q25H7DM1
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM36555 (3-Aminotyrosine) Show SMILES NC(Cc1ccc(O)c(N)c1)C(O)=O Show InChI InChI=1S/C9H12N2O3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,10-11H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.00E+5	-22.0	n/a	n/a	n/a	n/a	n/a	6.8	37
Binghamton University					Assay Description Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).				ACS Chem Biol 5: 777-85 (2010) Article DOI: 10.1021/cb100060v BindingDB Entry DOI: 10.7270/Q25H7DM1
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM36557 (3-Formyltyrosine) Show SMILES NC(Cc1ccc(O)c(C=O)c1)C(O)=O Show InChI InChI=1S/C10H11NO4/c11-8(10(14)15)4-6-1-2-9(13)7(3-6)5-12/h1-3,5,8,13H,4,11H2,(H,14,15)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.00E+5	-20.9	n/a	n/a	n/a	n/a	n/a	6.8	37
Binghamton University					Assay Description Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).				ACS Chem Biol 5: 777-85 (2010) Article DOI: 10.1021/cb100060v BindingDB Entry DOI: 10.7270/Q25H7DM1
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM36554 (3-Nitrotyrosine) Show SMILES NC(Cc1ccc(O)c(c1)N(=O)=O)C(O)=O Show InChI InChI=1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	4.00E+5	-20.2	n/a	n/a	n/a	n/a	n/a	6.8	37
Binghamton University					Assay Description Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).				ACS Chem Biol 5: 777-85 (2010) Article DOI: 10.1021/cb100060v BindingDB Entry DOI: 10.7270/Q25H7DM1
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM36558 (4-Aminophenylalanine) Show SMILES NC(Cc1ccc(N)cc1)C(O)=O Show InChI InChI=1S/C9H12N2O2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,10-11H2,(H,12,13)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents	Article PubMed	>4.00E+6	>-14.2	n/a	n/a	n/a	n/a	n/a	6.8	37
Binghamton University					Assay Description Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).				ACS Chem Biol 5: 777-85 (2010) Article DOI: 10.1021/cb100060v BindingDB Entry DOI: 10.7270/Q25H7DM1
					More data for this Ligand-Target Pair
Tubulin polyglutamylase TTLL7 (Mus musculus)	BDBM50437187 (CHEMBL2401837) Show SMILES CC(=O)NC(CCC(O)=O)P(O)(=O)CC(CCC(O)=O)C(O)=O Show InChI InChI=1S/C12H20NO9P/c1-7(14)13-9(3-5-11(17)18)23(21,22)6-8(12(19)20)2-4-10(15)16/h8-9H,2-6H2,1H3,(H,13,14)(H,15,16)(H,17,18)(H,19,20)(H,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of British Columbia Curated by ChEMBL					Assay Description Inhibition of mouse recombinant N-terminal GST-tagged TTLL7-mediated Ac-DATAEEEGEFEEEAEEEVA glutamylation expressed in Escherichia coli Rosetta2 DE3 ...				Bioorg Med Chem Lett 23: 4408-12 (2013) Article DOI: 10.1016/j.bmcl.2013.05.069 BindingDB Entry DOI: 10.7270/Q2MP54PM
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293293 (6alpha,8alpha-dihydroxy-23-oxo-labd-13(14),17-dien...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@H]2[C@@](C)(CCC[C@]12C)C=O)=C/C[C@H]1OC(=O)C=C1C |r,c:29| Show InChI InChI=1S/C25H38O5/c1-16(7-9-19-17(2)13-21(28)30-19)8-10-20-24(4)12-6-11-23(3,15-26)22(24)18(27)14-25(20,5)29/h7,13,15,18-20,22,27,29H,6,8-12,14H2,1-5H3/b16-7+/t18-,19+,20+,22-,23-,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293294 (6alpha,8alpha,15(S)-trihydroxy-23-oxo-labd-13(14),...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@H]2[C@@](C)(CCC[C@]12C)C=O)=C/[C@H](O)[C@H]1OC(=O)C=C1C |r,c:30| Show InChI InChI=1S/C25H38O6/c1-15(11-17(27)21-16(2)12-20(29)31-21)7-8-19-24(4)10-6-9-23(3,14-26)22(24)18(28)13-25(19,5)30/h11-12,14,17-19,21-22,27-28,30H,6-10,13H2,1-5H3/b15-11+/t17-,18-,19+,21-,22-,23-,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293295 (6alpha,8alpha,15(S)-trihydroxy-23-carbossimethylla...) Show SMILES COC(=O)[C@]1(C)CCC[C@]2(C)[C@@H](CC\C(C)=C\[C@H](O)[C@H]3OC(=O)C=C3C)[C@](C)(O)C[C@H](O)[C@@H]12 |r,c:23| Show InChI InChI=1S/C26H40O7/c1-15(12-17(27)21-16(2)13-20(29)33-21)8-9-19-24(3)10-7-11-25(4,23(30)32-6)22(24)18(28)14-26(19,5)31/h12-13,17-19,21-22,27-28,31H,7-11,14H2,1-6H3/b15-12+/t17-,18-,19+,21-,22+,24+,25+,26+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293296 (6alpha,8alpha-dihydroxy-23-carbossi-labd-13(14),17...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@@H]2[C@]1(C)CCC[C@@]2(C)C(O)=O)=C/CC1OC(=O)C=C1C |r,c:30| Show InChI InChI=1S/C25H38O6/c1-15(7-9-18-16(2)13-20(27)31-18)8-10-19-23(3)11-6-12-24(4,22(28)29)21(23)17(26)14-25(19,5)30/h7,13,17-19,21,26,30H,6,8-12,14H2,1-5H3,(H,28,29)/b15-7+/t17-,18?,19+,21+,23+,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293297 (6alpha,8alpha,15(S)-trihydroxy-23-carbossi-labd-13...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@@H]2[C@]1(C)CCC[C@@]2(C)C(O)=O)=C/[C@H](O)[C@H]1OC(=O)C=C1C |r,c:31| Show InChI InChI=1S/C25H38O7/c1-14(11-16(26)20-15(2)12-19(28)32-20)7-8-18-23(3)9-6-10-24(4,22(29)30)21(23)17(27)13-25(18,5)31/h11-12,16-18,20-21,26-27,31H,6-10,13H2,1-5H3,(H,29,30)/b14-11+/t16-,17-,18+,20-,21+,23+,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293298 (6alpha,8alpha,23-trihydroxy-labd-13(14),17-dien-16...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@H]2[C@](C)(CO)CCC[C@]12C)=C/C[C@H]1OC(=O)C=C1C |r,c:29| Show InChI InChI=1S/C25H40O5/c1-16(7-9-19-17(2)13-21(28)30-19)8-10-20-24(4)12-6-11-23(3,15-26)22(24)18(27)14-25(20,5)29/h7,13,18-20,22,26-27,29H,6,8-12,14-15H2,1-5H3/b16-7+/t18-,19+,20+,22-,23-,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293299 (6alpha,8alpha,15(S),23-tetrahydroxy-labd-13(14),17...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@H]2[C@](C)(CO)CCC[C@]12C)=C/[C@H](O)[C@H]1OC(=O)C=C1C |r,c:30| Show InChI InChI=1S/C25H40O6/c1-15(11-17(27)21-16(2)12-20(29)31-21)7-8-19-24(4)10-6-9-23(3,14-26)22(24)18(28)13-25(19,5)30/h11-12,17-19,21-22,26-28,30H,6-10,13-14H2,1-5H3/b15-11+/t17-,18-,19+,21-,22-,23-,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293300 (8alpha-hydroxy,23alpha-O-ethyl-23,6alpha-epoxy-lab...) Show SMILES CCO[C@H]1O[C@H]2C[C@@](C)(O)[C@H](CC\C(C)=C\C[C@H]3OC(=O)C=C3C)[C@@]3(C)CCC[C@]1(C)[C@H]23 |r,c:21| Show InChI InChI=1S/C27H42O5/c1-7-30-24-26(5)14-8-13-25(4)21(27(6,29)16-20(32-24)23(25)26)12-10-17(2)9-11-19-18(3)15-22(28)31-19/h9,15,19-21,23-24,29H,7-8,10-14,16H2,1-6H3/b17-9+/t19-,20+,21-,23-,24+,25-,26-,27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293301 (8alpha,15(S)-dihydroxy,23alpha-O-ethyl-23,6alpha-e...) Show SMILES CCO[C@H]1O[C@H]2C[C@@](C)(O)[C@H](CC\C(C)=C\[C@H](O)[C@H]3OC(=O)C=C3C)[C@@]3(C)CCC[C@]1(C)[C@H]23 |r,c:22| Show InChI InChI=1S/C27H42O6/c1-7-31-24-26(5)12-8-11-25(4)20(27(6,30)15-19(32-24)23(25)26)10-9-16(2)13-18(28)22-17(3)14-21(29)33-22/h13-14,18-20,22-24,28,30H,7-12,15H2,1-6H3/b16-13+/t18-,19-,20+,22-,23+,24-,25+,26+,27+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293302 (8alpha,15(S),23alpha-trihydroxy-23,6alpha-epoxy-la...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@@H]2O[C@H](O)[C@]3(C)CCC[C@@]1(C)[C@@H]23)=C/[C@H](O)[C@H]1OC(=O)C=C1C |r,c:31| Show InChI InChI=1S/C25H38O6/c1-14(11-16(26)20-15(2)12-19(27)31-20)7-8-18-23(3)9-6-10-24(4)21(23)17(30-22(24)28)13-25(18,5)29/h11-12,16-18,20-22,26,28-29H,6-10,13H2,1-5H3/b14-11+/t16-,17-,18+,20-,21+,22-,23+,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293292 (6alpha,15(S),23-trihydroxy-labd-8(22),13(14),17-tr...) Show SMILES C\C(CC[C@H]1C(=C)C[C@H](O)[C@H]2[C@](C)(CO)CCC[C@]12C)=C/[C@H](O)[C@H]1OC(=O)C=C1C |r,c:29| Show InChI InChI=1S/C25H38O5/c1-15(11-19(27)22-17(3)13-21(29)30-22)7-8-18-16(2)12-20(28)23-24(4,14-26)9-6-10-25(18,23)5/h11,13,18-20,22-23,26-28H,2,6-10,12,14H2,1,3-5H3/b15-11+/t18-,19-,20-,22-,23-,24-,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293290 (6alpha,8alpha,23-trihydroxy-labd-13(14),15,17-trie...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@H]2[C@](C)(CO)CCC[C@]12C)=C/C=C1\OC(=O)C=C1C |r,c:29| Show InChI InChI=1S/C25H38O5/c1-16(7-9-19-17(2)13-21(28)30-19)8-10-20-24(4)12-6-11-23(3,15-26)22(24)18(27)14-25(20,5)29/h7,9,13,18,20,22,26-27,29H,6,8,10-12,14-15H2,1-5H3/b16-7+,19-9-/t18-,20+,22-,23-,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293289 (6alpha,8alpha-dihydroxy-23-carbossi-labd-13(14),15...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@@H]2[C@]1(C)CCC[C@@]2(C)C(O)=O)=C/C=C1\OC(=O)C=C1C |r,c:30| Show InChI InChI=1S/C25H36O6/c1-15(7-9-18-16(2)13-20(27)31-18)8-10-19-23(3)11-6-12-24(4,22(28)29)21(23)17(26)14-25(19,5)30/h7,9,13,17,19,21,26,30H,6,8,10-12,14H2,1-5H3,(H,28,29)/b15-7+,18-9-/t17-,19+,21+,23+,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293288 (6alpha,8alpha-dihydroxy-23-oxo-13(14),15,17-trien-...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@H](O)[C@H]2[C@@](C)(CCC[C@]12C)C=O)=C/C=C1\OC(=O)C=C1C |r,c:29| Show InChI InChI=1S/C25H36O5/c1-16(7-9-19-17(2)13-21(28)30-19)8-10-20-24(4)12-6-11-23(3,15-26)22(24)18(27)14-25(20,5)29/h7,9,13,15,18,20,22,27,29H,6,8,10-12,14H2,1-5H3/b16-7+,19-9-/t18-,20+,22-,23-,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293287 (8alpha-hydroxylabd-13(14),15,17-trien-6alpha,23-16...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@@H]2OC(=O)[C@]3(C)CCC[C@@]1(C)[C@@H]23)=C/C=C1\OC(=O)C=C1C |r,c:30| Show InChI InChI=1S/C25H34O5/c1-15(7-9-17-16(2)13-20(26)29-17)8-10-19-23(3)11-6-12-24(4)21(23)18(30-22(24)27)14-25(19,5)28/h7,9,13,18-19,21,28H,6,8,10-12,14H2,1-5H3/b15-7+,17-9-/t18-,19+,21+,23+,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293286 (8alpha-23-dihydroxy-23,6alpha-epoxy-labd-13(14),15...) Show SMILES C\C(CC[C@H]1[C@](C)(O)C[C@@H]2OC(O)[C@]3(C)CCC[C@@]1(C)[C@@H]23)=C/C=C1\OC(=O)C=C1C |r,c:30| Show InChI InChI=1S/C25H36O5/c1-15(7-9-17-16(2)13-20(26)29-17)8-10-19-23(3)11-6-12-24(4)21(23)18(30-22(24)27)14-25(19,5)28/h7,9,13,18-19,21-22,27-28H,6,8,10-12,14H2,1-5H3/b15-7+,17-9-/t18-,19+,21+,22?,23+,24+,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293285 (23,6alpha-epoxy-labd-8,13(14),17-trien-16(R),19-ol...) Show SMILES C\C(CC[C@H]1C(=C)C[C@@H]2OC[C@]3(C)CCC[C@@]1(C)[C@@H]23)=C/C[C@H]1OC(=O)C=C1C |r,c:28| Show InChI InChI=1S/C25H36O3/c1-16(8-10-20-18(3)14-22(26)28-20)7-9-19-17(2)13-21-23-24(4,15-27-21)11-6-12-25(19,23)5/h8,14,19-21,23H,2,6-7,9-13,15H2,1,3-5H3/b16-8+/t19-,20+,21-,23-,24-,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair
Tubulin--tyrosine ligase (Homo sapiens (Human))	BDBM50293291 (6alpha,15(S)-dihydroxy-23-oxo-labd-8(22),13(14),17...) Show SMILES C\C(CC[C@H]1C(=C)C[C@H](O)[C@H]2[C@@](C)(CCC[C@]12C)C=O)=C/[C@H](O)[C@H]1OC(=O)C=C1C |r,c:29| Show InChI InChI=1S/C25H36O5/c1-15(11-19(27)22-17(3)13-21(29)30-22)7-8-18-16(2)12-20(28)23-24(4,14-26)9-6-10-25(18,23)5/h11,13-14,18-20,22-23,27-28H,2,6-10,12H2,1,3-5H3/b15-11+/t18-,19-,20-,22-,23-,24-,25+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a
Universita di Salerno Curated by ChEMBL					Assay Description Binding affinity to TTL by surface plasmon resonance				J Med Chem 52: 3814-28 (2009) Article DOI: 10.1021/jm801637f BindingDB Entry DOI: 10.7270/Q2JD4WQD
					More data for this Ligand-Target Pair