Found 419 hits Enz. Inhib. hit(s) with Target = 'Uracil nucleotide/cysteinyl leukotriene receptor' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50004952
(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)Show InChI InChI=1S/C12H9Cl2NO4/c13-5-3-7(14)10-6(1-2-9(16)17)11(12(18)19)15-8(10)4-5/h3-4,15H,1-2H2,(H,16,17)(H,18,19) | PDB
Reactome pathway
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| Article
PubMed
| 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by homologous competition binding assay in presence o... |
ACS Med Chem Lett 5: 326-30 (2014)
Article DOI: 10.1021/ml400399f
BindingDB Entry DOI: 10.7270/Q2445P0D |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50458837
(CHEMBL4206497)Show InChI InChI=1S/C18H23NO5/c1-2-3-4-5-10-24-12-6-7-13-14(8-9-16(20)21)17(18(22)23)19-15(13)11-12/h6-7,11,19H,2-5,8-10H2,1H3,(H,20,21)(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sultan Qaboos University
Curated by ChEMBL
| Assay Description
Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation counting |
J Med Chem 61: 8136-8154 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01768
BindingDB Entry DOI: 10.7270/Q28C9ZWJ |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50010475
(GAVESTINEL | GV-150526X)Show SMILES OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1\C=C\C(=O)Nc1ccccc1 Show InChI InChI=1S/C18H12Cl2N2O3/c19-10-8-13(20)16-12(17(18(24)25)22-14(16)9-10)6-7-15(23)21-11-4-2-1-3-5-11/h1-9,22H,(H,21,23)(H,24,25)/b7-6+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay |
ACS Med Chem Lett 5: 326-30 (2014)
Article DOI: 10.1021/ml400399f
BindingDB Entry DOI: 10.7270/Q2445P0D |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50004952
(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)Show InChI InChI=1S/C12H9Cl2NO4/c13-5-3-7(14)10-6(1-2-9(16)17)11(12(18)19)15-8(10)4-5/h3-4,15H,1-2H2,(H,16,17)(H,18,19) | PDB
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| Article
PubMed
| 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by competition binding assay |
ACS Med Chem Lett 5: 326-30 (2014)
Article DOI: 10.1021/ml400399f
BindingDB Entry DOI: 10.7270/Q2445P0D |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50004952
(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)Show InChI InChI=1S/C12H9Cl2NO4/c13-5-3-7(14)10-6(1-2-9(16)17)11(12(18)19)15-8(10)4-5/h3-4,15H,1-2H2,(H,16,17)(H,18,19) | PDB
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| Article
PubMed
| 2.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sultan Qaboos University
Curated by ChEMBL
| Assay Description
Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation counting |
J Med Chem 61: 8136-8154 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01768
BindingDB Entry DOI: 10.7270/Q28C9ZWJ |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50023198
(8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...)Show SMILES O=C(Nc1cccc2c1oc(cc2=O)-c1nnn[nH]1)c1ccc(OCCCCc2ccccc2)cc1 Show InChI InChI=1S/C27H23N5O4/c33-23-17-24(26-29-31-32-30-26)36-25-21(23)10-6-11-22(25)28-27(34)19-12-14-20(15-13-19)35-16-5-4-9-18-7-2-1-3-8-18/h1-3,6-8,10-15,17H,4-5,9,16H2,(H,28,34)(H,29,30,31,32) | PDB
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| Article
PubMed
| 4.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay |
ACS Med Chem Lett 5: 326-30 (2014)
Article DOI: 10.1021/ml400399f
BindingDB Entry DOI: 10.7270/Q2445P0D |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50052024
(CHEMBL787 | montelukast)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |r| Show InChI InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1 | PDB
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| Article
PubMed
| 6.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn
Curated by ChEMBL
| Assay Description
Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay |
ACS Med Chem Lett 5: 326-30 (2014)
Article DOI: 10.1021/ml400399f
BindingDB Entry DOI: 10.7270/Q2445P0D |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50458838
(CHEMBL4215280)Show SMILES CCCCCCOc1cc(Cl)c2c(CCC(O)=O)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C18H22ClNO5/c1-2-3-4-5-8-25-11-9-13(19)16-12(6-7-15(21)22)17(18(23)24)20-14(16)10-11/h9-10,20H,2-8H2,1H3,(H,21,22)(H,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sultan Qaboos University
Curated by ChEMBL
| Assay Description
Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation counting |
J Med Chem 61: 8136-8154 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01768
BindingDB Entry DOI: 10.7270/Q28C9ZWJ |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM50318031
(CHEMBL1097279 | cangrelor)Show SMILES CSCCNc1nc(SCCC(F)(F)F)nc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)C(Cl)(Cl)P([O-])([O-])=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H25Cl2F3N5O12P3S2/c1-43-5-3-23-12-9-13(26-15(25-12)44-4-2-16(20,21)22)27(7-24-9)14-11(29)10(28)8(38-14)6-37-42(35,36)39-41(33,34)17(18,19)40(30,31)32/h7-8,10-11,14,28-29H,2-6H2,1H3,(H,33,34)(H,35,36)(H,23,25,26)(H2,30,31,32)/p-4/t8-,10-,11-,14-/m1/s1 | PDB
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CHEMBL
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PC cid
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Similars
| Article
PubMed
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pavia
Curated by ChEMBL
| Assay Description
Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins... |
J Med Chem 53: 3489-501 (2010)
Article DOI: 10.1021/jm901691y
BindingDB Entry DOI: 10.7270/Q28C9WFW |
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646556
(6-chloro-N-[5-(3- fluoropropyl)-4,6-dimethoxy- pyr...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1CCCF | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646601
(6-chloro-7- (difluoromethylthio)-N-[5-(2- fluoroet...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(SC(F)F)c(Cl)ccc23)nc(OC)c1OCCF | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646694
(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(SC(F)F)c(Cl)ccc23)ncc1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646555
(6-chloro-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- ...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646738
(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(F)c(Br)ccc23)nc(OC)c1CCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646563
(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1CCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646588
(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Br)ccc23)nc(OC)c1CCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646655
(6-bromo-N-(4,6-dimethoxy-5- methyl-pyrimidin-2-yl)...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3nc(Br)ccc23)nc(OC)c1C | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646598
(N-[5-(2-cyanoethyl)-4,6- dimethoxy-pyrimidin-2-yl]...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(ccc23)C(F)F)nc(OC)c1OCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646548
(6-chloro-N-[5-(2- fluoroethoxy)-4,6-dimethoxy- pyr...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1OCCF | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646516
(6-chloro-N-[5-(3- fluoropropyl)-4-methoxy- pyrimid...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)ncc1CCCF | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646602
(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(SC(F)F)c(Cl)ccc23)nc(OC)c1CCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646557
(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1CCC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646681
(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(OC)c(Cl)ccc23)ncc1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646778
(US20240025883, Example 283)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(Br)c(Cl)ccc23)nc(OC)c1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646606
(6-bromo-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- p...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3nc(Br)ccc23)nc(OC)c1CC(F)CF | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646554
(6-chloro-N-[5-(2-fluoroethyl)- 4,6-dimethoxy-pyrim...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1CCF | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646551
(N-(5-allyl-4,6-dimethoxy- pyrimidin-2-yl)-6-chloro...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1CC=C | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646747
(N-[5-(2-cyanoethyl)-4,6- dimethoxy-pyrimidin-2-yl]...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(F)c(ccc23)C(F)F)nc(OC)c1CCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646760
(6-chloro-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrim...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1OCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646636
(7-bromo-6-chloro-N-[5-(2- fluoroethoxy)-4-methoxy-...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(Br)c(Cl)ccc23)ncc1OCCF | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646564
(6-chloro-N-(5-cyclopropyl- 4,6-dimethoxy-pyrimidin...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1C1CC1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646731
(N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(ccc23)C(F)F)nc(OC)c1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646600
(6-chloro-N-[5-(2-cyanoethyl)- 4-methoxy-pyrimidin-...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(SC(F)F)c(Cl)ccc23)ncc1CCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646702
(6-chloro-N-[5-(3,3- difluoropropyl)-4-methoxy- pyr...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(F)c(Cl)ccc23)ncc1CCC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646713
(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(F)c(Cl)ccc23)nc(OC)c1CCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646597
(N-[5-(2,2-difluoroethoxy)-4,6- dimethoxy-pyrimidin...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(ccc23)C(F)F)nc(OC)c1OCC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646667
(US20240025883, Example 172)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3nc(Br)ccc23)nc(OC)c1OC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646739
(6-bromo-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrimi...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(F)c(Br)ccc23)nc(OC)c1OCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646616
(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3nc(Cl)ccc23)nc(OC)c1CCC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646729
(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(SC)c(Cl)ccc23)ncc1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646691
(6-bromo-N-[5-(2,2- difluoroethyl)-4-methoxy- pyrim...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(OC)c(Br)ccc23)ncc1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646607
(6-bromo-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy-...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3nc(Br)ccc23)nc(OC)c1CCC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646549
(6-chloro-N-[5-(2,2- difluoroethoxy)-4,6- dimethoxy...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1OCC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646712
(6-chloro-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- ...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(F)c(Cl)ccc23)nc(OC)c1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646553
(6-chloro-N-(4,6-dimethoxy-5- propyl-pyrimidin-2-yl...)Show SMILES CCCc1c(OC)nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc1OC | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646550
(6-chloro-N-[4,6-dimethoxy-5- (1,1,2- trifluoroetho...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc(OC)c1OC(F)(F)CF | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646587
(6-bromo-N-[5-(2,2- difluoroethoxy)-4,6- dimethoxy-...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(Br)ccc23)nc(OC)c1OCC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646714
(6-chloro-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrim...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(F)c(Cl)ccc23)nc(OC)c1OCC#N | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646705
(6,7-dichloro-N-[5-(2,2- difluoroethyl)-4-methoxy- ...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(Cl)c(Cl)ccc23)ncc1CC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Uracil nucleotide/cysteinyl leukotriene receptor
(Homo sapiens (Human)) | BDBM646682
(6-chloro-N-[5-(3,3- difluoropropyl)-4-methoxy- pyr...)Show SMILES COc1nc(NS(=O)(=O)c2c[nH]c3c(OC)c(Cl)ccc23)ncc1CCC(F)F | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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