Found 73 hits Enz. Inhib. hit(s) with Target = 'Vasoactive intestinal polypeptide receptor 1' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50435130
(CHEMBL1893324)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O Show InChI InChI=1S/C147H238N44O42S/c1-18-75(12)115(143(231)182-97(56-72(6)7)131(219)174-94(118(156)206)61-108(153)199)189-140(228)106(68-193)186-135(223)102(63-110(155)201)179-132(220)96(55-71(4)5)176-133(221)98(58-81-37-41-84(196)42-38-81)177-126(214)88(33-23-26-49-149)168-124(212)89(34-24-27-50-150)172-141(229)113(73(8)9)187-119(207)76(13)165-122(210)93(47-53-234-17)171-128(216)92(45-46-107(152)198)170-123(211)87(32-22-25-48-148)167-125(213)90(35-28-51-162-146(157)158)169-130(218)95(54-70(2)3)175-127(215)91(36-29-52-163-147(159)160)173-144(232)116(78(15)194)190-137(225)99(59-82-39-43-85(197)44-40-82)178-134(222)101(62-109(154)200)180-136(224)104(65-112(204)205)184-145(233)117(79(16)195)191-138(226)100(57-80-30-20-19-21-31-80)183-142(230)114(74(10)11)188-120(208)77(14)166-129(217)103(64-111(202)203)181-139(227)105(67-192)185-121(209)86(151)60-83-66-161-69-164-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,192-197H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,198)(H2,153,199)(H2,154,200)(H2,155,201)(H2,156,206)(H,161,164)(H,165,210)(H,166,217)(H,167,213)(H,168,212)(H,169,218)(H,170,211)(H,171,216)(H,172,229)(H,173,232)(H,174,219)(H,175,215)(H,176,221)(H,177,214)(H,178,222)(H,179,220)(H,180,224)(H,181,227)(H,182,231)(H,183,230)(H,184,233)(H,185,209)(H,186,223)(H,187,207)(H,188,208)(H,189,228)(H,190,225)(H,191,226)(H,202,203)(H,204,205)(H4,157,158,162)(H4,159,160,163)/t75-,76-,77-,78+,79+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,113-,114-,115-,116-,117-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.0670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Binding affinity to human VPAC1 receptor by radioligand displacement assay |
Eur J Med Chem 63: 85-94 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.044
BindingDB Entry DOI: 10.7270/Q2JH3NKC |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM81828
(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)Show SMILES CCC(C)C(NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(N)=O)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(C)C)C(C)O)C(C)O)C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(N)=O)C(O)=O |(16.32,19.93,;16.32,18.39,;17.66,17.62,;18.99,18.39,;17.66,16.08,;18.99,15.31,;20.53,16.08,;20.53,17.62,;21.86,15.31,;21.86,13.77,;20.53,13,;23.2,16.08,;24.74,15.31,;24.74,13.77,;26.07,16.08,;26.07,17.62,;24.74,18.39,;24.74,19.93,;23.4,17.62,;27.41,15.31,;28.95,16.08,;28.95,17.62,;30.28,15.31,;30.28,13.77,;28.95,13,;28.95,11.46,;27.61,13.77,;31.61,16.08,;33.15,15.31,;33.15,13.77,;34.49,16.08,;34.49,17.62,;35.82,18.39,;37.15,17.62,;38.49,18.39,;38.49,19.93,;39.82,20.7,;37.15,20.7,;35.82,19.93,;35.82,15.31,;35.1,4.53,;35.1,2.99,;33.76,5.3,;33.76,6.84,;35.1,7.61,;36.43,6.84,;37.77,7.61,;39.1,6.84,;32.43,4.53,;30.89,5.3,;30.89,6.84,;29.56,4.53,;29.56,2.99,;30.89,2.22,;30.89,.68,;32.22,-.09,;33.56,.68,;28.22,5.3,;26.68,4.53,;26.68,2.99,;25.35,5.3,;24.02,4.53,;22.48,5.3,;22.48,6.84,;21.14,4.53,;21.14,2.99,;19.81,5.3,;18.27,4.53,;18.27,2.99,;16.93,5.3,;16.93,6.84,;18.27,7.61,;18.27,9.15,;16.93,9.92,;15.6,4.53,;14.06,5.3,;14.06,6.84,;12.73,4.53,;12.73,2.99,;14.06,2.22,;14.06,.68,;12.73,-.09,;15.39,-.09,;11.39,5.3,;9.85,4.53,;9.85,2.99,;8.52,5.3,;8.52,6.84,;7.19,7.61,;7.19,9.15,;5.85,9.92,;4.52,9.15,;7.19,4.53,;7.91,-6.25,;7.91,-7.79,;9.24,-5.48,;9.24,-3.94,;7.91,-3.17,;7.91,-1.63,;6.57,-.86,;5.24,-1.63,;3.91,-.86,;5.24,-3.17,;10.58,-6.25,;12.12,-5.48,;12.12,-3.94,;13.45,-6.25,;13.45,-7.79,;12.12,-8.56,;12.12,-10.1,;10.78,-7.79,;14.78,-5.48,;16.32,-6.25,;16.32,-7.79,;17.66,-5.48,;17.66,-3.94,;16.32,-3.17,;16.32,-1.63,;17.66,-.86,;17.66,.68,;18.99,1.45,;16.32,1.45,;18.99,-6.25,;20.53,-5.48,;20.53,-3.94,;21.86,-6.25,;23.2,-5.48,;24.74,-6.25,;24.74,-7.79,;26.07,-5.48,;26.07,-3.94,;24.74,-3.17,;24.74,-1.63,;23.4,-.86,;22.07,-1.63,;20.74,-.86,;22.07,-3.17,;23.4,-3.94,;27.41,-6.25,;28.95,-5.48,;28.95,-3.94,;30.28,-6.25,;30.28,-7.79,;28.95,-8.56,;28.95,-10.1,;27.61,-7.79,;31.61,-5.48,;33.15,-6.25,;33.15,-7.79,;34.49,-5.48,;34.49,-3.94,;35.82,-3.17,;35.82,-1.63,;37.15,-3.94,;35.82,-6.25,;35.1,-17.03,;35.1,-18.57,;33.76,-16.26,;32.43,-17.03,;30.89,-16.26,;30.89,-14.72,;29.56,-17.03,;29.56,-18.57,;30.89,-19.34,;30.89,-20.88,;32.22,-21.65,;33.56,-20.88,;33.56,-19.34,;32.22,-18.57,;28.22,-16.26,;26.68,-17.03,;26.68,-18.57,;25.35,-16.26,;24.02,-17.03,;22.48,-16.26,;22.48,-14.72,;21.14,-17.03,;21.14,-18.57,;19.81,-16.26,;18.27,-17.03,;18.27,-18.57,;16.93,-16.26,;16.93,-14.72,;18.27,-13.95,;18.27,-12.41,;19.6,-14.72,;15.6,-17.03,;14.06,-16.26,;14.06,-14.72,;12.73,-17.03,;12.73,-18.57,;14.06,-19.34,;11.39,-16.26,;9.85,-17.03,;9.85,-18.57,;8.52,-16.26,;7.19,-17.03,;8.52,-14.72,;7.19,-13.95,;7.03,-12.42,;5.52,-12.1,;4.75,-13.43,;5.78,-14.58,;25.35,-14.72,;26.68,-13.95,;24.02,-13.95,;33.76,-14.72,;32.43,-13.95,;35.1,-13.95,;21.86,-7.79,;23.2,-8.56,;20.53,-8.56,;25.35,6.84,;26.68,7.61,;24.02,7.61,;16.32,15.31,;16.32,13.77,;14.78,16.08,;13.45,15.31,;13.45,13.77,;12.12,13,;12.12,11.46,;10.78,13.77,;12.12,16.08,;12.12,17.62,;10.58,15.31,;9.24,16.08,;9.24,17.62,;7.91,18.39,;7.91,19.93,;6.57,17.62,;7.91,15.31,;6.57,16.08,;7.91,13.77,)| Show InChI InChI=1S/C147H237N43O43S/c1-18-75(12)115(142(229)180-96(56-72(6)7)131(218)183-104(145(232)233)63-110(155)200)188-139(226)106(68-192)185-134(221)101(62-109(154)199)177-130(217)95(55-71(4)5)174-132(219)97(58-81-37-41-84(195)42-38-81)175-125(212)88(33-23-26-49-149)167-123(210)89(34-24-27-50-150)171-140(227)113(73(8)9)186-118(205)76(13)164-121(208)93(47-53-234-17)170-127(214)92(45-46-107(152)197)169-122(209)87(32-22-25-48-148)166-124(211)90(35-28-51-161-146(156)157)168-129(216)94(54-70(2)3)173-126(213)91(36-29-52-162-147(158)159)172-143(230)116(78(15)193)189-136(223)98(59-82-39-43-85(196)44-40-82)176-133(220)100(61-108(153)198)178-135(222)103(65-112(203)204)182-144(231)117(79(16)194)190-137(224)99(57-80-30-20-19-21-31-80)181-141(228)114(74(10)11)187-119(206)77(14)165-128(215)102(64-111(201)202)179-138(225)105(67-191)184-120(207)86(151)60-83-66-160-69-163-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,191-196H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,197)(H2,153,198)(H2,154,199)(H2,155,200)(H,160,163)(H,164,208)(H,165,215)(H,166,211)(H,167,210)(H,168,216)(H,169,209)(H,170,214)(H,171,227)(H,172,230)(H,173,213)(H,174,219)(H,175,212)(H,176,220)(H,177,217)(H,178,222)(H,179,225)(H,180,229)(H,181,228)(H,182,231)(H,183,218)(H,184,207)(H,185,221)(H,186,205)(H,187,206)(H,188,226)(H,189,223)(H,190,224)(H,201,202)(H,203,204)(H,232,233)(H4,156,157,161)(H4,158,159,162) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 445-60 (2002)
Article DOI: 10.1124/jpet.102.038075
BindingDB Entry DOI: 10.7270/Q2R78CSR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM81828
(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)Show SMILES CCC(C)C(NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(N)=O)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(C)C)C(C)O)C(C)O)C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(N)=O)C(O)=O |(16.32,19.93,;16.32,18.39,;17.66,17.62,;18.99,18.39,;17.66,16.08,;18.99,15.31,;20.53,16.08,;20.53,17.62,;21.86,15.31,;21.86,13.77,;20.53,13,;23.2,16.08,;24.74,15.31,;24.74,13.77,;26.07,16.08,;26.07,17.62,;24.74,18.39,;24.74,19.93,;23.4,17.62,;27.41,15.31,;28.95,16.08,;28.95,17.62,;30.28,15.31,;30.28,13.77,;28.95,13,;28.95,11.46,;27.61,13.77,;31.61,16.08,;33.15,15.31,;33.15,13.77,;34.49,16.08,;34.49,17.62,;35.82,18.39,;37.15,17.62,;38.49,18.39,;38.49,19.93,;39.82,20.7,;37.15,20.7,;35.82,19.93,;35.82,15.31,;35.1,4.53,;35.1,2.99,;33.76,5.3,;33.76,6.84,;35.1,7.61,;36.43,6.84,;37.77,7.61,;39.1,6.84,;32.43,4.53,;30.89,5.3,;30.89,6.84,;29.56,4.53,;29.56,2.99,;30.89,2.22,;30.89,.68,;32.22,-.09,;33.56,.68,;28.22,5.3,;26.68,4.53,;26.68,2.99,;25.35,5.3,;24.02,4.53,;22.48,5.3,;22.48,6.84,;21.14,4.53,;21.14,2.99,;19.81,5.3,;18.27,4.53,;18.27,2.99,;16.93,5.3,;16.93,6.84,;18.27,7.61,;18.27,9.15,;16.93,9.92,;15.6,4.53,;14.06,5.3,;14.06,6.84,;12.73,4.53,;12.73,2.99,;14.06,2.22,;14.06,.68,;12.73,-.09,;15.39,-.09,;11.39,5.3,;9.85,4.53,;9.85,2.99,;8.52,5.3,;8.52,6.84,;7.19,7.61,;7.19,9.15,;5.85,9.92,;4.52,9.15,;7.19,4.53,;7.91,-6.25,;7.91,-7.79,;9.24,-5.48,;9.24,-3.94,;7.91,-3.17,;7.91,-1.63,;6.57,-.86,;5.24,-1.63,;3.91,-.86,;5.24,-3.17,;10.58,-6.25,;12.12,-5.48,;12.12,-3.94,;13.45,-6.25,;13.45,-7.79,;12.12,-8.56,;12.12,-10.1,;10.78,-7.79,;14.78,-5.48,;16.32,-6.25,;16.32,-7.79,;17.66,-5.48,;17.66,-3.94,;16.32,-3.17,;16.32,-1.63,;17.66,-.86,;17.66,.68,;18.99,1.45,;16.32,1.45,;18.99,-6.25,;20.53,-5.48,;20.53,-3.94,;21.86,-6.25,;23.2,-5.48,;24.74,-6.25,;24.74,-7.79,;26.07,-5.48,;26.07,-3.94,;24.74,-3.17,;24.74,-1.63,;23.4,-.86,;22.07,-1.63,;20.74,-.86,;22.07,-3.17,;23.4,-3.94,;27.41,-6.25,;28.95,-5.48,;28.95,-3.94,;30.28,-6.25,;30.28,-7.79,;28.95,-8.56,;28.95,-10.1,;27.61,-7.79,;31.61,-5.48,;33.15,-6.25,;33.15,-7.79,;34.49,-5.48,;34.49,-3.94,;35.82,-3.17,;35.82,-1.63,;37.15,-3.94,;35.82,-6.25,;35.1,-17.03,;35.1,-18.57,;33.76,-16.26,;32.43,-17.03,;30.89,-16.26,;30.89,-14.72,;29.56,-17.03,;29.56,-18.57,;30.89,-19.34,;30.89,-20.88,;32.22,-21.65,;33.56,-20.88,;33.56,-19.34,;32.22,-18.57,;28.22,-16.26,;26.68,-17.03,;26.68,-18.57,;25.35,-16.26,;24.02,-17.03,;22.48,-16.26,;22.48,-14.72,;21.14,-17.03,;21.14,-18.57,;19.81,-16.26,;18.27,-17.03,;18.27,-18.57,;16.93,-16.26,;16.93,-14.72,;18.27,-13.95,;18.27,-12.41,;19.6,-14.72,;15.6,-17.03,;14.06,-16.26,;14.06,-14.72,;12.73,-17.03,;12.73,-18.57,;14.06,-19.34,;11.39,-16.26,;9.85,-17.03,;9.85,-18.57,;8.52,-16.26,;7.19,-17.03,;8.52,-14.72,;7.19,-13.95,;7.03,-12.42,;5.52,-12.1,;4.75,-13.43,;5.78,-14.58,;25.35,-14.72,;26.68,-13.95,;24.02,-13.95,;33.76,-14.72,;32.43,-13.95,;35.1,-13.95,;21.86,-7.79,;23.2,-8.56,;20.53,-8.56,;25.35,6.84,;26.68,7.61,;24.02,7.61,;16.32,15.31,;16.32,13.77,;14.78,16.08,;13.45,15.31,;13.45,13.77,;12.12,13,;12.12,11.46,;10.78,13.77,;12.12,16.08,;12.12,17.62,;10.58,15.31,;9.24,16.08,;9.24,17.62,;7.91,18.39,;7.91,19.93,;6.57,17.62,;7.91,15.31,;6.57,16.08,;7.91,13.77,)| Show InChI InChI=1S/C147H237N43O43S/c1-18-75(12)115(142(229)180-96(56-72(6)7)131(218)183-104(145(232)233)63-110(155)200)188-139(226)106(68-192)185-134(221)101(62-109(154)199)177-130(217)95(55-71(4)5)174-132(219)97(58-81-37-41-84(195)42-38-81)175-125(212)88(33-23-26-49-149)167-123(210)89(34-24-27-50-150)171-140(227)113(73(8)9)186-118(205)76(13)164-121(208)93(47-53-234-17)170-127(214)92(45-46-107(152)197)169-122(209)87(32-22-25-48-148)166-124(211)90(35-28-51-161-146(156)157)168-129(216)94(54-70(2)3)173-126(213)91(36-29-52-162-147(158)159)172-143(230)116(78(15)193)189-136(223)98(59-82-39-43-85(196)44-40-82)176-133(220)100(61-108(153)198)178-135(222)103(65-112(203)204)182-144(231)117(79(16)194)190-137(224)99(57-80-30-20-19-21-31-80)181-141(228)114(74(10)11)187-119(206)77(14)165-128(215)102(64-111(201)202)179-138(225)105(67-191)184-120(207)86(151)60-83-66-160-69-163-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,191-196H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,197)(H2,153,198)(H2,154,199)(H2,155,200)(H,160,163)(H,164,208)(H,165,215)(H,166,211)(H,167,210)(H,168,216)(H,169,209)(H,170,214)(H,171,227)(H,172,230)(H,173,213)(H,174,219)(H,175,212)(H,176,220)(H,177,217)(H,178,222)(H,179,225)(H,180,229)(H,181,228)(H,182,231)(H,183,218)(H,184,207)(H,185,221)(H,186,205)(H,187,206)(H,188,226)(H,189,223)(H,190,224)(H,201,202)(H,203,204)(H,232,233)(H4,156,157,161)(H4,158,159,162) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 445-60 (2002)
Article DOI: 10.1124/jpet.102.038075
BindingDB Entry DOI: 10.7270/Q2R78CSR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM81828
(CAS_37221-79-7 | VIP(4-28) | Vasoactive intestinal...)Show SMILES CCC(C)C(NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(N)=O)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(C)C)C(C)O)C(C)O)C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(N)=O)C(O)=O |(16.32,19.93,;16.32,18.39,;17.66,17.62,;18.99,18.39,;17.66,16.08,;18.99,15.31,;20.53,16.08,;20.53,17.62,;21.86,15.31,;21.86,13.77,;20.53,13,;23.2,16.08,;24.74,15.31,;24.74,13.77,;26.07,16.08,;26.07,17.62,;24.74,18.39,;24.74,19.93,;23.4,17.62,;27.41,15.31,;28.95,16.08,;28.95,17.62,;30.28,15.31,;30.28,13.77,;28.95,13,;28.95,11.46,;27.61,13.77,;31.61,16.08,;33.15,15.31,;33.15,13.77,;34.49,16.08,;34.49,17.62,;35.82,18.39,;37.15,17.62,;38.49,18.39,;38.49,19.93,;39.82,20.7,;37.15,20.7,;35.82,19.93,;35.82,15.31,;35.1,4.53,;35.1,2.99,;33.76,5.3,;33.76,6.84,;35.1,7.61,;36.43,6.84,;37.77,7.61,;39.1,6.84,;32.43,4.53,;30.89,5.3,;30.89,6.84,;29.56,4.53,;29.56,2.99,;30.89,2.22,;30.89,.68,;32.22,-.09,;33.56,.68,;28.22,5.3,;26.68,4.53,;26.68,2.99,;25.35,5.3,;24.02,4.53,;22.48,5.3,;22.48,6.84,;21.14,4.53,;21.14,2.99,;19.81,5.3,;18.27,4.53,;18.27,2.99,;16.93,5.3,;16.93,6.84,;18.27,7.61,;18.27,9.15,;16.93,9.92,;15.6,4.53,;14.06,5.3,;14.06,6.84,;12.73,4.53,;12.73,2.99,;14.06,2.22,;14.06,.68,;12.73,-.09,;15.39,-.09,;11.39,5.3,;9.85,4.53,;9.85,2.99,;8.52,5.3,;8.52,6.84,;7.19,7.61,;7.19,9.15,;5.85,9.92,;4.52,9.15,;7.19,4.53,;7.91,-6.25,;7.91,-7.79,;9.24,-5.48,;9.24,-3.94,;7.91,-3.17,;7.91,-1.63,;6.57,-.86,;5.24,-1.63,;3.91,-.86,;5.24,-3.17,;10.58,-6.25,;12.12,-5.48,;12.12,-3.94,;13.45,-6.25,;13.45,-7.79,;12.12,-8.56,;12.12,-10.1,;10.78,-7.79,;14.78,-5.48,;16.32,-6.25,;16.32,-7.79,;17.66,-5.48,;17.66,-3.94,;16.32,-3.17,;16.32,-1.63,;17.66,-.86,;17.66,.68,;18.99,1.45,;16.32,1.45,;18.99,-6.25,;20.53,-5.48,;20.53,-3.94,;21.86,-6.25,;23.2,-5.48,;24.74,-6.25,;24.74,-7.79,;26.07,-5.48,;26.07,-3.94,;24.74,-3.17,;24.74,-1.63,;23.4,-.86,;22.07,-1.63,;20.74,-.86,;22.07,-3.17,;23.4,-3.94,;27.41,-6.25,;28.95,-5.48,;28.95,-3.94,;30.28,-6.25,;30.28,-7.79,;28.95,-8.56,;28.95,-10.1,;27.61,-7.79,;31.61,-5.48,;33.15,-6.25,;33.15,-7.79,;34.49,-5.48,;34.49,-3.94,;35.82,-3.17,;35.82,-1.63,;37.15,-3.94,;35.82,-6.25,;35.1,-17.03,;35.1,-18.57,;33.76,-16.26,;32.43,-17.03,;30.89,-16.26,;30.89,-14.72,;29.56,-17.03,;29.56,-18.57,;30.89,-19.34,;30.89,-20.88,;32.22,-21.65,;33.56,-20.88,;33.56,-19.34,;32.22,-18.57,;28.22,-16.26,;26.68,-17.03,;26.68,-18.57,;25.35,-16.26,;24.02,-17.03,;22.48,-16.26,;22.48,-14.72,;21.14,-17.03,;21.14,-18.57,;19.81,-16.26,;18.27,-17.03,;18.27,-18.57,;16.93,-16.26,;16.93,-14.72,;18.27,-13.95,;18.27,-12.41,;19.6,-14.72,;15.6,-17.03,;14.06,-16.26,;14.06,-14.72,;12.73,-17.03,;12.73,-18.57,;14.06,-19.34,;11.39,-16.26,;9.85,-17.03,;9.85,-18.57,;8.52,-16.26,;7.19,-17.03,;8.52,-14.72,;7.19,-13.95,;7.03,-12.42,;5.52,-12.1,;4.75,-13.43,;5.78,-14.58,;25.35,-14.72,;26.68,-13.95,;24.02,-13.95,;33.76,-14.72,;32.43,-13.95,;35.1,-13.95,;21.86,-7.79,;23.2,-8.56,;20.53,-8.56,;25.35,6.84,;26.68,7.61,;24.02,7.61,;16.32,15.31,;16.32,13.77,;14.78,16.08,;13.45,15.31,;13.45,13.77,;12.12,13,;12.12,11.46,;10.78,13.77,;12.12,16.08,;12.12,17.62,;10.58,15.31,;9.24,16.08,;9.24,17.62,;7.91,18.39,;7.91,19.93,;6.57,17.62,;7.91,15.31,;6.57,16.08,;7.91,13.77,)| Show InChI InChI=1S/C147H237N43O43S/c1-18-75(12)115(142(229)180-96(56-72(6)7)131(218)183-104(145(232)233)63-110(155)200)188-139(226)106(68-192)185-134(221)101(62-109(154)199)177-130(217)95(55-71(4)5)174-132(219)97(58-81-37-41-84(195)42-38-81)175-125(212)88(33-23-26-49-149)167-123(210)89(34-24-27-50-150)171-140(227)113(73(8)9)186-118(205)76(13)164-121(208)93(47-53-234-17)170-127(214)92(45-46-107(152)197)169-122(209)87(32-22-25-48-148)166-124(211)90(35-28-51-161-146(156)157)168-129(216)94(54-70(2)3)173-126(213)91(36-29-52-162-147(158)159)172-143(230)116(78(15)193)189-136(223)98(59-82-39-43-85(196)44-40-82)176-133(220)100(61-108(153)198)178-135(222)103(65-112(203)204)182-144(231)117(79(16)194)190-137(224)99(57-80-30-20-19-21-31-80)181-141(228)114(74(10)11)187-119(206)77(14)165-128(215)102(64-111(201)202)179-138(225)105(67-191)184-120(207)86(151)60-83-66-160-69-163-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,191-196H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,197)(H2,153,198)(H2,154,199)(H2,155,200)(H,160,163)(H,164,208)(H,165,215)(H,166,211)(H,167,210)(H,168,216)(H,169,209)(H,170,214)(H,171,227)(H,172,230)(H,173,213)(H,174,219)(H,175,212)(H,176,220)(H,177,217)(H,178,222)(H,179,225)(H,180,229)(H,181,228)(H,182,231)(H,183,218)(H,184,207)(H,185,221)(H,186,205)(H,187,206)(H,188,226)(H,189,223)(H,190,224)(H,201,202)(H,203,204)(H,232,233)(H4,156,157,161)(H4,158,159,162) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 445-60 (2002)
Article DOI: 10.1124/jpet.102.038075
BindingDB Entry DOI: 10.7270/Q2R78CSR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM86051
(CAS_0 | NSC_0 | [Lys15, Arg16, Leu27]VIP(1-7)GRF(8...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |wU:122.129,109.109,92.97,72.76,61.61,25.29,4.4,218.220,164.173,179.181,192.196,wD:151.157,145.148,133.142,113.118,101.105,80.88,66.68,50.57,41.46,33.37,16.21,8.12,2.2,175.177,160.161,184.190,209.213,198.200,(-8.97,-.35,;-8.97,-1.85,;-7.67,-2.57,;-6.31,-1.78,;-7.63,-4.11,;-8.97,-4.99,;-10.28,-4.21,;-10.28,-2.68,;-11.69,-4.99,;-11.69,-6.66,;-10.26,-7.26,;-8.92,-6.45,;-10.26,-8.83,;-13.01,-4.3,;-14.31,-5.04,;-14.31,-6.66,;-15.65,-4.21,;-16.99,-4.99,;-16.99,-6.54,;-18.3,-7.26,;-19.67,-6.45,;-18.3,-8.81,;-15.65,-2.68,;-16.94,-1.94,;-18.28,-2.68,;-16.99,-.35,;-15.76,.37,;-15.76,1.8,;-14.4,2.63,;-17.03,2.59,;-18.3,.37,;-19.62,-.35,;-19.62,-1.94,;-21.03,.37,;-22.19,-.35,;-22.19,-1.99,;-23.41,-2.84,;-20.82,-2.57,;-21.1,1.99,;-22.53,2.63,;-24.04,1.8,;-22.49,4.11,;-23.74,4.92,;-25.12,4.32,;-26.32,5.11,;-27.69,4.41,;-28.96,5.22,;-21.1,4.83,;-20.94,6.38,;-22.28,7.26,;-19.55,7.03,;-19.48,8.64,;-20.82,9.5,;-20.78,10.98,;-22.19,11.81,;-22.14,13.4,;-23.53,14.14,;-20.82,14.14,;-18.28,6.26,;-16.94,6.89,;-16.94,8.44,;-15.76,5.99,;-15.76,4.51,;-14.33,6.7,;-13.15,5.87,;-13.15,4.32,;-11.69,6.47,;-11.6,8.02,;-12.76,8.9,;-10.49,5.57,;-9.22,6.42,;-9.22,8.02,;-7.86,5.66,;-7.93,4.09,;-9.24,3.35,;-9.24,1.87,;-10.54,4.11,;-6.49,6.42,;-5.25,5.66,;-5.25,3.95,;-3.81,6.42,;-3.81,8.02,;-5.27,8.78,;-5.25,10.26,;-6.56,11.06,;-6.56,12.6,;-7.9,13.37,;-7.9,14.91,;-8.99,12.28,;-2.52,5.73,;-1.16,6.47,;-1.16,8.02,;-.02,5.57,;-.02,4.03,;1.07,2.94,;.67,1.45,;1.76,.36,;1.36,-1.12,;1.25,6.38,;2.5,5.52,;2.5,3.79,;3.81,6.29,;3.79,7.88,;2.5,8.64,;1.18,7.74,;2.43,10.1,;5.25,5.55,;6.52,6.38,;6.52,7.93,;7.79,5.55,;9.13,6.26,;10.45,5.52,;10.38,3.95,;11.76,6.17,;11.83,7.72,;10.58,8.51,;10.58,10.05,;9.41,10.86,;9.43,12.41,;13.15,5.32,;14.49,5.99,;14.49,7.53,;15.92,5.25,;15.92,3.67,;14.54,2.87,;14.63,1.34,;13.2,.65,;13.2,-.99,;11.83,-1.71,;14.42,-1.83,;17.24,5.99,;18.49,5.32,;18.49,3.77,;19.9,6.1,;19.9,7.63,;18.6,8.44,;18.6,9.96,;17.33,10.68,;15.92,9.96,;14.77,10.79,;15.92,8.3,;17.29,7.72,;21.12,5.25,;22.39,6.1,;22.39,7.72,;23.71,5.32,;25.19,6.17,;25.19,7.74,;23.71,3.79,;24.91,3.07,;26.09,3.79,;24.91,1.53,;26.35,.88,;27.69,1.62,;29.06,.92,;30.39,1.69,;29.06,-.62,;23.76,.65,;23.06,-.7,;21.54,-.7,;23.76,-2.05,;23.06,-3.4,;23.8,-4.75,;25.33,-4.75,;23.06,-6.06,;21.54,-6.06,;20.75,-4.75,;19.18,-4.75,;18.44,-3.4,;19.18,-2.05,;20.71,-2.05,;21.54,-3.4,;23.8,-7.37,;23.15,-8.72,;21.36,-8.72,;23.89,-10.2,;23.15,-11.68,;23.8,-12.99,;25.37,-12.99,;23.15,-14.29,;21.58,-14.29,;23.8,-15.65,;23.15,-17,;21.58,-17,;23.84,-18.35,;25.37,-18.35,;26.11,-17,;27.68,-17,;25.34,-15.66,;23.19,-19.7,;23.84,-20.96,;25.37,-20.96,;23.19,-22.31,;21.65,-22.31,;20.88,-20.98,;23.84,-23.62,;23.19,-24.92,;21.58,-24.92,;23.84,-26.27,;23.19,-27.58,;25.41,-26.27,;26.18,-27.61,;25.78,-29.09,;27.08,-29.93,;28.27,-28.96,;27.72,-27.53,;25.43,-10.2,;26.2,-8.87,;26.52,-11.29,;25.33,-2.05,;26.07,-3.4,;26.07,-.7,;7.79,3.91,;9.04,3.24,;6.33,3.24,;-6.29,-4.85,;-6.29,-6.4,;-4.95,-4.11,;-3.56,-4.92,;-2.2,-4.11,;-2.17,-2.63,;-3.49,-1.85,;-.84,-1.86,;-3.61,-6.47,;-2.24,-7.19,;-4.99,-7.3,)| Show InChI InChI=1S/C144H244N44O38/c1-20-78(16)113(140(225)173-95(115(151)200)56-71(2)3)187-134(219)103(65-110(198)199)178-124(209)93(46-48-107(149)194)171-128(213)96(57-72(4)5)176-130(215)97(58-73(6)7)174-122(207)88(37-25-29-51-146)166-120(205)91(40-32-54-160-143(154)155)165-116(201)79(17)164-135(220)104(67-189)184-131(216)98(59-74(8)9)175-123(208)89(39-27-31-53-159-142(152)153)167-119(204)87(36-24-28-50-145)169-129(214)99(60-75(10)11)180-139(224)112(77(14)15)186-126(211)90(38-26-30-52-147)168-121(206)92(41-33-55-161-144(156)157)170-132(217)100(62-83-42-44-85(193)45-43-83)177-137(222)106(69-191)183-125(210)94(47-49-108(150)195)172-141(226)114(81(19)192)188-133(218)101(61-82-34-22-21-23-35-82)181-138(223)111(76(12)13)185-117(202)80(18)163-127(212)102(64-109(196)197)179-136(221)105(68-190)182-118(203)86(148)63-84-66-158-70-162-84/h21-23,34-35,42-45,66,70-81,86-106,111-114,189-193H,20,24-33,36-41,46-65,67-69,145-148H2,1-19H3,(H2,149,194)(H2,150,195)(H2,151,200)(H,158,162)(H,163,212)(H,164,220)(H,165,201)(H,166,205)(H,167,204)(H,168,206)(H,169,214)(H,170,217)(H,171,213)(H,172,226)(H,173,225)(H,174,207)(H,175,208)(H,176,215)(H,177,222)(H,178,209)(H,179,221)(H,180,224)(H,181,223)(H,182,203)(H,183,210)(H,184,216)(H,185,202)(H,186,211)(H,187,219)(H,188,218)(H,196,197)(H,198,199)(H4,152,153,159)(H4,154,155,160)(H4,156,157,161)/t78-,79-,80-,81+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 445-60 (2002)
Article DOI: 10.1124/jpet.102.038075
BindingDB Entry DOI: 10.7270/Q2R78CSR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM86051
(CAS_0 | NSC_0 | [Lys15, Arg16, Leu27]VIP(1-7)GRF(8...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |wU:122.129,109.109,92.97,72.76,61.61,25.29,4.4,218.220,164.173,179.181,192.196,wD:151.157,145.148,133.142,113.118,101.105,80.88,66.68,50.57,41.46,33.37,16.21,8.12,2.2,175.177,160.161,184.190,209.213,198.200,(-8.97,-.35,;-8.97,-1.85,;-7.67,-2.57,;-6.31,-1.78,;-7.63,-4.11,;-8.97,-4.99,;-10.28,-4.21,;-10.28,-2.68,;-11.69,-4.99,;-11.69,-6.66,;-10.26,-7.26,;-8.92,-6.45,;-10.26,-8.83,;-13.01,-4.3,;-14.31,-5.04,;-14.31,-6.66,;-15.65,-4.21,;-16.99,-4.99,;-16.99,-6.54,;-18.3,-7.26,;-19.67,-6.45,;-18.3,-8.81,;-15.65,-2.68,;-16.94,-1.94,;-18.28,-2.68,;-16.99,-.35,;-15.76,.37,;-15.76,1.8,;-14.4,2.63,;-17.03,2.59,;-18.3,.37,;-19.62,-.35,;-19.62,-1.94,;-21.03,.37,;-22.19,-.35,;-22.19,-1.99,;-23.41,-2.84,;-20.82,-2.57,;-21.1,1.99,;-22.53,2.63,;-24.04,1.8,;-22.49,4.11,;-23.74,4.92,;-25.12,4.32,;-26.32,5.11,;-27.69,4.41,;-28.96,5.22,;-21.1,4.83,;-20.94,6.38,;-22.28,7.26,;-19.55,7.03,;-19.48,8.64,;-20.82,9.5,;-20.78,10.98,;-22.19,11.81,;-22.14,13.4,;-23.53,14.14,;-20.82,14.14,;-18.28,6.26,;-16.94,6.89,;-16.94,8.44,;-15.76,5.99,;-15.76,4.51,;-14.33,6.7,;-13.15,5.87,;-13.15,4.32,;-11.69,6.47,;-11.6,8.02,;-12.76,8.9,;-10.49,5.57,;-9.22,6.42,;-9.22,8.02,;-7.86,5.66,;-7.93,4.09,;-9.24,3.35,;-9.24,1.87,;-10.54,4.11,;-6.49,6.42,;-5.25,5.66,;-5.25,3.95,;-3.81,6.42,;-3.81,8.02,;-5.27,8.78,;-5.25,10.26,;-6.56,11.06,;-6.56,12.6,;-7.9,13.37,;-7.9,14.91,;-8.99,12.28,;-2.52,5.73,;-1.16,6.47,;-1.16,8.02,;-.02,5.57,;-.02,4.03,;1.07,2.94,;.67,1.45,;1.76,.36,;1.36,-1.12,;1.25,6.38,;2.5,5.52,;2.5,3.79,;3.81,6.29,;3.79,7.88,;2.5,8.64,;1.18,7.74,;2.43,10.1,;5.25,5.55,;6.52,6.38,;6.52,7.93,;7.79,5.55,;9.13,6.26,;10.45,5.52,;10.38,3.95,;11.76,6.17,;11.83,7.72,;10.58,8.51,;10.58,10.05,;9.41,10.86,;9.43,12.41,;13.15,5.32,;14.49,5.99,;14.49,7.53,;15.92,5.25,;15.92,3.67,;14.54,2.87,;14.63,1.34,;13.2,.65,;13.2,-.99,;11.83,-1.71,;14.42,-1.83,;17.24,5.99,;18.49,5.32,;18.49,3.77,;19.9,6.1,;19.9,7.63,;18.6,8.44,;18.6,9.96,;17.33,10.68,;15.92,9.96,;14.77,10.79,;15.92,8.3,;17.29,7.72,;21.12,5.25,;22.39,6.1,;22.39,7.72,;23.71,5.32,;25.19,6.17,;25.19,7.74,;23.71,3.79,;24.91,3.07,;26.09,3.79,;24.91,1.53,;26.35,.88,;27.69,1.62,;29.06,.92,;30.39,1.69,;29.06,-.62,;23.76,.65,;23.06,-.7,;21.54,-.7,;23.76,-2.05,;23.06,-3.4,;23.8,-4.75,;25.33,-4.75,;23.06,-6.06,;21.54,-6.06,;20.75,-4.75,;19.18,-4.75,;18.44,-3.4,;19.18,-2.05,;20.71,-2.05,;21.54,-3.4,;23.8,-7.37,;23.15,-8.72,;21.36,-8.72,;23.89,-10.2,;23.15,-11.68,;23.8,-12.99,;25.37,-12.99,;23.15,-14.29,;21.58,-14.29,;23.8,-15.65,;23.15,-17,;21.58,-17,;23.84,-18.35,;25.37,-18.35,;26.11,-17,;27.68,-17,;25.34,-15.66,;23.19,-19.7,;23.84,-20.96,;25.37,-20.96,;23.19,-22.31,;21.65,-22.31,;20.88,-20.98,;23.84,-23.62,;23.19,-24.92,;21.58,-24.92,;23.84,-26.27,;23.19,-27.58,;25.41,-26.27,;26.18,-27.61,;25.78,-29.09,;27.08,-29.93,;28.27,-28.96,;27.72,-27.53,;25.43,-10.2,;26.2,-8.87,;26.52,-11.29,;25.33,-2.05,;26.07,-3.4,;26.07,-.7,;7.79,3.91,;9.04,3.24,;6.33,3.24,;-6.29,-4.85,;-6.29,-6.4,;-4.95,-4.11,;-3.56,-4.92,;-2.2,-4.11,;-2.17,-2.63,;-3.49,-1.85,;-.84,-1.86,;-3.61,-6.47,;-2.24,-7.19,;-4.99,-7.3,)| Show InChI InChI=1S/C144H244N44O38/c1-20-78(16)113(140(225)173-95(115(151)200)56-71(2)3)187-134(219)103(65-110(198)199)178-124(209)93(46-48-107(149)194)171-128(213)96(57-72(4)5)176-130(215)97(58-73(6)7)174-122(207)88(37-25-29-51-146)166-120(205)91(40-32-54-160-143(154)155)165-116(201)79(17)164-135(220)104(67-189)184-131(216)98(59-74(8)9)175-123(208)89(39-27-31-53-159-142(152)153)167-119(204)87(36-24-28-50-145)169-129(214)99(60-75(10)11)180-139(224)112(77(14)15)186-126(211)90(38-26-30-52-147)168-121(206)92(41-33-55-161-144(156)157)170-132(217)100(62-83-42-44-85(193)45-43-83)177-137(222)106(69-191)183-125(210)94(47-49-108(150)195)172-141(226)114(81(19)192)188-133(218)101(61-82-34-22-21-23-35-82)181-138(223)111(76(12)13)185-117(202)80(18)163-127(212)102(64-109(196)197)179-136(221)105(68-190)182-118(203)86(148)63-84-66-158-70-162-84/h21-23,34-35,42-45,66,70-81,86-106,111-114,189-193H,20,24-33,36-41,46-65,67-69,145-148H2,1-19H3,(H2,149,194)(H2,150,195)(H2,151,200)(H,158,162)(H,163,212)(H,164,220)(H,165,201)(H,166,205)(H,167,204)(H,168,206)(H,169,214)(H,170,217)(H,171,213)(H,172,226)(H,173,225)(H,174,207)(H,175,208)(H,176,215)(H,177,222)(H,178,209)(H,179,221)(H,180,224)(H,181,223)(H,182,203)(H,183,210)(H,184,216)(H,185,202)(H,186,211)(H,187,219)(H,188,218)(H,196,197)(H,198,199)(H4,152,153,159)(H4,154,155,160)(H4,156,157,161)/t78-,79-,80-,81+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 445-60 (2002)
Article DOI: 10.1124/jpet.102.038075
BindingDB Entry DOI: 10.7270/Q2R78CSR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM86051
(CAS_0 | NSC_0 | [Lys15, Arg16, Leu27]VIP(1-7)GRF(8...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |wU:122.129,109.109,92.97,72.76,61.61,25.29,4.4,218.220,164.173,179.181,192.196,wD:151.157,145.148,133.142,113.118,101.105,80.88,66.68,50.57,41.46,33.37,16.21,8.12,2.2,175.177,160.161,184.190,209.213,198.200,(-8.97,-.35,;-8.97,-1.85,;-7.67,-2.57,;-6.31,-1.78,;-7.63,-4.11,;-8.97,-4.99,;-10.28,-4.21,;-10.28,-2.68,;-11.69,-4.99,;-11.69,-6.66,;-10.26,-7.26,;-8.92,-6.45,;-10.26,-8.83,;-13.01,-4.3,;-14.31,-5.04,;-14.31,-6.66,;-15.65,-4.21,;-16.99,-4.99,;-16.99,-6.54,;-18.3,-7.26,;-19.67,-6.45,;-18.3,-8.81,;-15.65,-2.68,;-16.94,-1.94,;-18.28,-2.68,;-16.99,-.35,;-15.76,.37,;-15.76,1.8,;-14.4,2.63,;-17.03,2.59,;-18.3,.37,;-19.62,-.35,;-19.62,-1.94,;-21.03,.37,;-22.19,-.35,;-22.19,-1.99,;-23.41,-2.84,;-20.82,-2.57,;-21.1,1.99,;-22.53,2.63,;-24.04,1.8,;-22.49,4.11,;-23.74,4.92,;-25.12,4.32,;-26.32,5.11,;-27.69,4.41,;-28.96,5.22,;-21.1,4.83,;-20.94,6.38,;-22.28,7.26,;-19.55,7.03,;-19.48,8.64,;-20.82,9.5,;-20.78,10.98,;-22.19,11.81,;-22.14,13.4,;-23.53,14.14,;-20.82,14.14,;-18.28,6.26,;-16.94,6.89,;-16.94,8.44,;-15.76,5.99,;-15.76,4.51,;-14.33,6.7,;-13.15,5.87,;-13.15,4.32,;-11.69,6.47,;-11.6,8.02,;-12.76,8.9,;-10.49,5.57,;-9.22,6.42,;-9.22,8.02,;-7.86,5.66,;-7.93,4.09,;-9.24,3.35,;-9.24,1.87,;-10.54,4.11,;-6.49,6.42,;-5.25,5.66,;-5.25,3.95,;-3.81,6.42,;-3.81,8.02,;-5.27,8.78,;-5.25,10.26,;-6.56,11.06,;-6.56,12.6,;-7.9,13.37,;-7.9,14.91,;-8.99,12.28,;-2.52,5.73,;-1.16,6.47,;-1.16,8.02,;-.02,5.57,;-.02,4.03,;1.07,2.94,;.67,1.45,;1.76,.36,;1.36,-1.12,;1.25,6.38,;2.5,5.52,;2.5,3.79,;3.81,6.29,;3.79,7.88,;2.5,8.64,;1.18,7.74,;2.43,10.1,;5.25,5.55,;6.52,6.38,;6.52,7.93,;7.79,5.55,;9.13,6.26,;10.45,5.52,;10.38,3.95,;11.76,6.17,;11.83,7.72,;10.58,8.51,;10.58,10.05,;9.41,10.86,;9.43,12.41,;13.15,5.32,;14.49,5.99,;14.49,7.53,;15.92,5.25,;15.92,3.67,;14.54,2.87,;14.63,1.34,;13.2,.65,;13.2,-.99,;11.83,-1.71,;14.42,-1.83,;17.24,5.99,;18.49,5.32,;18.49,3.77,;19.9,6.1,;19.9,7.63,;18.6,8.44,;18.6,9.96,;17.33,10.68,;15.92,9.96,;14.77,10.79,;15.92,8.3,;17.29,7.72,;21.12,5.25,;22.39,6.1,;22.39,7.72,;23.71,5.32,;25.19,6.17,;25.19,7.74,;23.71,3.79,;24.91,3.07,;26.09,3.79,;24.91,1.53,;26.35,.88,;27.69,1.62,;29.06,.92,;30.39,1.69,;29.06,-.62,;23.76,.65,;23.06,-.7,;21.54,-.7,;23.76,-2.05,;23.06,-3.4,;23.8,-4.75,;25.33,-4.75,;23.06,-6.06,;21.54,-6.06,;20.75,-4.75,;19.18,-4.75,;18.44,-3.4,;19.18,-2.05,;20.71,-2.05,;21.54,-3.4,;23.8,-7.37,;23.15,-8.72,;21.36,-8.72,;23.89,-10.2,;23.15,-11.68,;23.8,-12.99,;25.37,-12.99,;23.15,-14.29,;21.58,-14.29,;23.8,-15.65,;23.15,-17,;21.58,-17,;23.84,-18.35,;25.37,-18.35,;26.11,-17,;27.68,-17,;25.34,-15.66,;23.19,-19.7,;23.84,-20.96,;25.37,-20.96,;23.19,-22.31,;21.65,-22.31,;20.88,-20.98,;23.84,-23.62,;23.19,-24.92,;21.58,-24.92,;23.84,-26.27,;23.19,-27.58,;25.41,-26.27,;26.18,-27.61,;25.78,-29.09,;27.08,-29.93,;28.27,-28.96,;27.72,-27.53,;25.43,-10.2,;26.2,-8.87,;26.52,-11.29,;25.33,-2.05,;26.07,-3.4,;26.07,-.7,;7.79,3.91,;9.04,3.24,;6.33,3.24,;-6.29,-4.85,;-6.29,-6.4,;-4.95,-4.11,;-3.56,-4.92,;-2.2,-4.11,;-2.17,-2.63,;-3.49,-1.85,;-.84,-1.86,;-3.61,-6.47,;-2.24,-7.19,;-4.99,-7.3,)| Show InChI InChI=1S/C144H244N44O38/c1-20-78(16)113(140(225)173-95(115(151)200)56-71(2)3)187-134(219)103(65-110(198)199)178-124(209)93(46-48-107(149)194)171-128(213)96(57-72(4)5)176-130(215)97(58-73(6)7)174-122(207)88(37-25-29-51-146)166-120(205)91(40-32-54-160-143(154)155)165-116(201)79(17)164-135(220)104(67-189)184-131(216)98(59-74(8)9)175-123(208)89(39-27-31-53-159-142(152)153)167-119(204)87(36-24-28-50-145)169-129(214)99(60-75(10)11)180-139(224)112(77(14)15)186-126(211)90(38-26-30-52-147)168-121(206)92(41-33-55-161-144(156)157)170-132(217)100(62-83-42-44-85(193)45-43-83)177-137(222)106(69-191)183-125(210)94(47-49-108(150)195)172-141(226)114(81(19)192)188-133(218)101(61-82-34-22-21-23-35-82)181-138(223)111(76(12)13)185-117(202)80(18)163-127(212)102(64-109(196)197)179-136(221)105(68-190)182-118(203)86(148)63-84-66-158-70-162-84/h21-23,34-35,42-45,66,70-81,86-106,111-114,189-193H,20,24-33,36-41,46-65,67-69,145-148H2,1-19H3,(H2,149,194)(H2,150,195)(H2,151,200)(H,158,162)(H,163,212)(H,164,220)(H,165,201)(H,166,205)(H,167,204)(H,168,206)(H,169,214)(H,170,217)(H,171,213)(H,172,226)(H,173,225)(H,174,207)(H,175,208)(H,176,215)(H,177,222)(H,178,209)(H,179,221)(H,180,224)(H,181,223)(H,182,203)(H,183,210)(H,184,216)(H,185,202)(H,186,211)(H,187,219)(H,188,218)(H,196,197)(H,198,199)(H4,152,153,159)(H4,154,155,160)(H4,156,157,161)/t78-,79-,80-,81+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 445-60 (2002)
Article DOI: 10.1124/jpet.102.038075
BindingDB Entry DOI: 10.7270/Q2R78CSR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM86050
(Ac-L-His-L-Ser-L-Asp-L-Ala-L-Val-L-Phe-L-Thr-L-Glu...)Show SMILES CSCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)C(NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(C)C)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)O)C(N)=O |r,wU:102.104,87.88,111.117,139.143,70.75,125.134,142.146,37.41,17.22,4.4,153.156,167.169,188.191,204.207,220.223,246.249,wD:91.100,106.108,78.84,119.123,58.67,45.50,26.33,8.13,148.151,158.160,176.178,196.199,212.215,229.232,(12.13,4.79,;10.78,4.01,;10.78,2.48,;9.39,1.74,;9.39,.22,;7.99,-.48,;6.69,.22,;6.73,1.79,;5.34,-.48,;5.34,-2.05,;6.69,-2.83,;6.64,-4.36,;7.95,-5.14,;5.29,-5.1,;4.03,.26,;2.68,-.44,;2.64,-2,;1.33,.31,;1.33,1.83,;2.68,2.57,;2.68,4.14,;4.07,4.92,;4.07,6.49,;.02,-.39,;-1.24,.31,;-1.2,1.83,;-2.55,-.39,;-2.59,-2,;-1.24,-2.74,;-1.24,-4.27,;.02,-5.05,;.02,-6.58,;-1.24,-7.36,;1.33,-7.41,;-3.9,.31,;-5.25,-.39,;-5.25,-1.96,;-6.55,.31,;-6.55,1.87,;-5.25,2.61,;-5.25,4.14,;-3.9,1.87,;-7.91,-.39,;-9.26,.35,;-9.21,1.87,;-10.56,-.39,;-10.61,-1.96,;-9.26,-2.7,;-9.26,-4.27,;-7.91,-5.01,;-7.91,-6.58,;-11.91,.35,;-13.22,-.35,;-13.22,-1.96,;-14.57,.35,;-15.92,-.35,;-17.27,.35,;-17.23,1.92,;-18.62,-.35,;-18.62,-1.87,;-17.27,-2.7,;-17.27,-4.23,;-15.92,-4.97,;-14.57,-4.23,;-13.26,-5.01,;-14.57,-2.7,;-15.92,-1.96,;-19.93,.35,;-21.24,-.35,;-21.24,-1.87,;-22.59,.39,;-22.59,1.92,;-21.24,2.66,;-19.93,1.92,;-21.24,4.23,;-23.94,-.31,;-25.29,.39,;-25.29,1.92,;-26.64,-.31,;-26.64,-1.87,;-25.29,-2.66,;-25.29,-4.2,;-23.8,-4.6,;-26.38,-5.29,;-27.9,.39,;-29.25,-.31,;-29.25,-1.83,;-30.6,.39,;-31.95,-.31,;-33.3,.44,;-33.3,1.96,;-34.61,-.31,;-34.61,-1.83,;-33.3,-2.61,;-33.3,-4.18,;-31.95,-4.92,;-30.6,-4.18,;-30.6,-2.66,;-31.95,-1.83,;-35.92,.44,;-37.27,-.22,;-37.27,-2,;-38.75,.52,;-40.23,-.22,;-41.53,.44,;-41.53,2,;-42.84,-.22,;-42.84,-1.79,;-44.19,.44,;-45.54,-.22,;-45.54,-1.79,;-46.89,.48,;-46.89,2,;-45.54,2.74,;-45.54,4.31,;-44.21,1.97,;-48.24,-.17,;-49.51,.48,;-49.51,2,;-50.86,-.17,;-50.86,-1.71,;-49.52,-2.48,;-52.16,.48,;-53.47,-.17,;-53.47,-1.79,;-54.82,.48,;-54.82,2.05,;-56.15,2.82,;-57.64,2.42,;-58.48,3.71,;-57.51,4.91,;-56.07,4.35,;-56.13,-.17,;-56.13,-1.71,;-54.79,-2.48,;-57.46,-2.48,;-38.75,2.06,;-37.41,2.83,;-39.84,3.15,;-30.6,1.96,;-31.95,2.7,;-29.25,2.7,;-14.57,1.87,;-15.92,2.66,;-13.22,2.66,;10.74,-.52,;10.69,-2.09,;12.09,.17,;13.4,-.57,;13.4,-2.13,;14.75,.13,;14.79,1.7,;16.05,-.61,;17.4,.09,;17.45,1.66,;18.75,-.61,;18.71,-2.22,;20.1,.09,;21.41,-.65,;21.41,-2.22,;22.72,-3.01,;22.67,-4.57,;24.02,-5.36,;23.98,-6.93,;22.72,.04,;22.76,1.57,;24.07,-.7,;25.42,-0,;25.46,1.57,;26.81,2.27,;26.81,3.83,;28.21,4.57,;28.21,6.1,;26.72,-.74,;26.72,-2.31,;28.12,-.04,;29.38,-.78,;29.34,-2.35,;30.69,-3.14,;30.65,-4.7,;32,-5.53,;33.35,-4.75,;34.65,-5.58,;33.39,-3.22,;32.04,-2.44,;30.73,-.04,;30.78,1.44,;32.08,-.83,;33.43,-.09,;33.48,1.35,;34.83,2.09,;34.87,3.66,;36.09,1.26,;34.74,-.92,;34.74,-2.48,;36.09,-.13,;37.4,-.96,;37.35,-2.53,;38.7,-3.31,;40.05,-2.61,;38.66,-4.88,;38.75,-.17,;38.79,1.22,;40.1,-1,;41.45,-.31,;41.49,1.18,;42.84,1.92,;44.18,1.15,;42.84,3.46,;42.75,-1.05,;42.75,-2.66,;44.11,-.35,;45.41,-1.13,;45.37,-2.7,;46.72,-3.48,;46.67,-5.01,;48.05,-2.71,;46.76,-.39,;46.81,1.05,;48.11,-1.18,;49.46,-.44,;49.51,1,;50.81,1.79,;50.86,3.31,;52.19,4.08,;52.19,5.62,;50.73,-1.22,;50.73,-2.83,;52.12,-.52,;53.43,-1.31,;53.38,-2.87,;54.73,-3.7,;54.69,-5.24,;56.02,-6.01,;56.02,-7.55,;54.78,-.57,;54.82,.92,;56.13,-1.35,;57.46,-.58,;58.79,-1.35,;58.79,-2.89,;60.13,-.58,;61.46,-1.35,;62.8,-.58,;62.8,.96,;64.13,-1.35,;65.46,-.58,;65.46,.96,;64.13,1.73,;66.55,2.05,;66.8,-1.35,;68.13,-.58,;66.8,-2.89,)| Show InChI InChI=1S/C159H258N46O47S/c1-79(2)63-106(191-141(235)101(40-25-31-60-165)189-157(251)128(87(13)208)204-153(247)110(68-92-44-48-95(212)49-45-92)195-150(244)113(70-119(167)214)196-143(237)104(51-53-123(218)219)190-158(252)129(88(14)209)205-154(248)111(66-90-33-18-17-19-34-90)200-156(250)126(82(7)8)203-133(227)85(11)179-144(238)115(72-124(220)221)199-155(249)117(77-206)201-149(243)112(180-89(15)210)69-93-74-172-78-176-93)145(239)186-102(41-32-61-173-159(170)171)139(233)183-98(37-22-28-57-162)138(232)187-103(50-52-118(166)213)142(236)188-105(54-62-253-16)135(229)178-83(9)131(225)177-84(10)132(226)181-97(36-21-27-56-161)136(230)184-100(39-24-30-59-164)140(234)194-109(67-91-42-46-94(211)47-43-91)148(242)192-108(65-81(5)6)147(241)197-114(71-120(168)215)151(245)198-116(73-125(222)223)152(246)193-107(64-80(3)4)146(240)185-99(38-23-29-58-163)137(231)182-96(35-20-26-55-160)134(228)175-75-121(216)174-76-122(217)202-127(86(12)207)130(169)224/h17-19,33-34,42-49,74,78-88,96-117,126-129,206-209,211-212H,20-32,35-41,50-73,75-77,160-165H2,1-16H3,(H2,166,213)(H2,167,214)(H2,168,215)(H2,169,224)(H,172,176)(H,174,216)(H,175,228)(H,177,225)(H,178,229)(H,179,238)(H,180,210)(H,181,226)(H,182,231)(H,183,233)(H,184,230)(H,185,240)(H,186,239)(H,187,232)(H,188,236)(H,189,251)(H,190,252)(H,191,235)(H,192,242)(H,193,246)(H,194,234)(H,195,244)(H,196,237)(H,197,241)(H,198,245)(H,199,249)(H,200,250)(H,201,243)(H,202,217)(H,203,227)(H,204,247)(H,205,248)(H,218,219)(H,220,221)(H,222,223)(H4,170,171,173)/t83-,84-,85-,86?,87+,88+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,126-,127-,128?,129-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 445-60 (2002)
Article DOI: 10.1124/jpet.102.038075
BindingDB Entry DOI: 10.7270/Q2R78CSR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM86050
(Ac-L-His-L-Ser-L-Asp-L-Ala-L-Val-L-Phe-L-Thr-L-Glu...)Show SMILES CSCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)C(NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(C)C)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)O)C(N)=O |r,wU:102.104,87.88,111.117,139.143,70.75,125.134,142.146,37.41,17.22,4.4,153.156,167.169,188.191,204.207,220.223,246.249,wD:91.100,106.108,78.84,119.123,58.67,45.50,26.33,8.13,148.151,158.160,176.178,196.199,212.215,229.232,(12.13,4.79,;10.78,4.01,;10.78,2.48,;9.39,1.74,;9.39,.22,;7.99,-.48,;6.69,.22,;6.73,1.79,;5.34,-.48,;5.34,-2.05,;6.69,-2.83,;6.64,-4.36,;7.95,-5.14,;5.29,-5.1,;4.03,.26,;2.68,-.44,;2.64,-2,;1.33,.31,;1.33,1.83,;2.68,2.57,;2.68,4.14,;4.07,4.92,;4.07,6.49,;.02,-.39,;-1.24,.31,;-1.2,1.83,;-2.55,-.39,;-2.59,-2,;-1.24,-2.74,;-1.24,-4.27,;.02,-5.05,;.02,-6.58,;-1.24,-7.36,;1.33,-7.41,;-3.9,.31,;-5.25,-.39,;-5.25,-1.96,;-6.55,.31,;-6.55,1.87,;-5.25,2.61,;-5.25,4.14,;-3.9,1.87,;-7.91,-.39,;-9.26,.35,;-9.21,1.87,;-10.56,-.39,;-10.61,-1.96,;-9.26,-2.7,;-9.26,-4.27,;-7.91,-5.01,;-7.91,-6.58,;-11.91,.35,;-13.22,-.35,;-13.22,-1.96,;-14.57,.35,;-15.92,-.35,;-17.27,.35,;-17.23,1.92,;-18.62,-.35,;-18.62,-1.87,;-17.27,-2.7,;-17.27,-4.23,;-15.92,-4.97,;-14.57,-4.23,;-13.26,-5.01,;-14.57,-2.7,;-15.92,-1.96,;-19.93,.35,;-21.24,-.35,;-21.24,-1.87,;-22.59,.39,;-22.59,1.92,;-21.24,2.66,;-19.93,1.92,;-21.24,4.23,;-23.94,-.31,;-25.29,.39,;-25.29,1.92,;-26.64,-.31,;-26.64,-1.87,;-25.29,-2.66,;-25.29,-4.2,;-23.8,-4.6,;-26.38,-5.29,;-27.9,.39,;-29.25,-.31,;-29.25,-1.83,;-30.6,.39,;-31.95,-.31,;-33.3,.44,;-33.3,1.96,;-34.61,-.31,;-34.61,-1.83,;-33.3,-2.61,;-33.3,-4.18,;-31.95,-4.92,;-30.6,-4.18,;-30.6,-2.66,;-31.95,-1.83,;-35.92,.44,;-37.27,-.22,;-37.27,-2,;-38.75,.52,;-40.23,-.22,;-41.53,.44,;-41.53,2,;-42.84,-.22,;-42.84,-1.79,;-44.19,.44,;-45.54,-.22,;-45.54,-1.79,;-46.89,.48,;-46.89,2,;-45.54,2.74,;-45.54,4.31,;-44.21,1.97,;-48.24,-.17,;-49.51,.48,;-49.51,2,;-50.86,-.17,;-50.86,-1.71,;-49.52,-2.48,;-52.16,.48,;-53.47,-.17,;-53.47,-1.79,;-54.82,.48,;-54.82,2.05,;-56.15,2.82,;-57.64,2.42,;-58.48,3.71,;-57.51,4.91,;-56.07,4.35,;-56.13,-.17,;-56.13,-1.71,;-54.79,-2.48,;-57.46,-2.48,;-38.75,2.06,;-37.41,2.83,;-39.84,3.15,;-30.6,1.96,;-31.95,2.7,;-29.25,2.7,;-14.57,1.87,;-15.92,2.66,;-13.22,2.66,;10.74,-.52,;10.69,-2.09,;12.09,.17,;13.4,-.57,;13.4,-2.13,;14.75,.13,;14.79,1.7,;16.05,-.61,;17.4,.09,;17.45,1.66,;18.75,-.61,;18.71,-2.22,;20.1,.09,;21.41,-.65,;21.41,-2.22,;22.72,-3.01,;22.67,-4.57,;24.02,-5.36,;23.98,-6.93,;22.72,.04,;22.76,1.57,;24.07,-.7,;25.42,-0,;25.46,1.57,;26.81,2.27,;26.81,3.83,;28.21,4.57,;28.21,6.1,;26.72,-.74,;26.72,-2.31,;28.12,-.04,;29.38,-.78,;29.34,-2.35,;30.69,-3.14,;30.65,-4.7,;32,-5.53,;33.35,-4.75,;34.65,-5.58,;33.39,-3.22,;32.04,-2.44,;30.73,-.04,;30.78,1.44,;32.08,-.83,;33.43,-.09,;33.48,1.35,;34.83,2.09,;34.87,3.66,;36.09,1.26,;34.74,-.92,;34.74,-2.48,;36.09,-.13,;37.4,-.96,;37.35,-2.53,;38.7,-3.31,;40.05,-2.61,;38.66,-4.88,;38.75,-.17,;38.79,1.22,;40.1,-1,;41.45,-.31,;41.49,1.18,;42.84,1.92,;44.18,1.15,;42.84,3.46,;42.75,-1.05,;42.75,-2.66,;44.11,-.35,;45.41,-1.13,;45.37,-2.7,;46.72,-3.48,;46.67,-5.01,;48.05,-2.71,;46.76,-.39,;46.81,1.05,;48.11,-1.18,;49.46,-.44,;49.51,1,;50.81,1.79,;50.86,3.31,;52.19,4.08,;52.19,5.62,;50.73,-1.22,;50.73,-2.83,;52.12,-.52,;53.43,-1.31,;53.38,-2.87,;54.73,-3.7,;54.69,-5.24,;56.02,-6.01,;56.02,-7.55,;54.78,-.57,;54.82,.92,;56.13,-1.35,;57.46,-.58,;58.79,-1.35,;58.79,-2.89,;60.13,-.58,;61.46,-1.35,;62.8,-.58,;62.8,.96,;64.13,-1.35,;65.46,-.58,;65.46,.96,;64.13,1.73,;66.55,2.05,;66.8,-1.35,;68.13,-.58,;66.8,-2.89,)| Show InChI InChI=1S/C159H258N46O47S/c1-79(2)63-106(191-141(235)101(40-25-31-60-165)189-157(251)128(87(13)208)204-153(247)110(68-92-44-48-95(212)49-45-92)195-150(244)113(70-119(167)214)196-143(237)104(51-53-123(218)219)190-158(252)129(88(14)209)205-154(248)111(66-90-33-18-17-19-34-90)200-156(250)126(82(7)8)203-133(227)85(11)179-144(238)115(72-124(220)221)199-155(249)117(77-206)201-149(243)112(180-89(15)210)69-93-74-172-78-176-93)145(239)186-102(41-32-61-173-159(170)171)139(233)183-98(37-22-28-57-162)138(232)187-103(50-52-118(166)213)142(236)188-105(54-62-253-16)135(229)178-83(9)131(225)177-84(10)132(226)181-97(36-21-27-56-161)136(230)184-100(39-24-30-59-164)140(234)194-109(67-91-42-46-94(211)47-43-91)148(242)192-108(65-81(5)6)147(241)197-114(71-120(168)215)151(245)198-116(73-125(222)223)152(246)193-107(64-80(3)4)146(240)185-99(38-23-29-58-163)137(231)182-96(35-20-26-55-160)134(228)175-75-121(216)174-76-122(217)202-127(86(12)207)130(169)224/h17-19,33-34,42-49,74,78-88,96-117,126-129,206-209,211-212H,20-32,35-41,50-73,75-77,160-165H2,1-16H3,(H2,166,213)(H2,167,214)(H2,168,215)(H2,169,224)(H,172,176)(H,174,216)(H,175,228)(H,177,225)(H,178,229)(H,179,238)(H,180,210)(H,181,226)(H,182,231)(H,183,233)(H,184,230)(H,185,240)(H,186,239)(H,187,232)(H,188,236)(H,189,251)(H,190,252)(H,191,235)(H,192,242)(H,193,246)(H,194,234)(H,195,244)(H,196,237)(H,197,241)(H,198,245)(H,199,249)(H,200,250)(H,201,243)(H,202,217)(H,203,227)(H,204,247)(H,205,248)(H,218,219)(H,220,221)(H,222,223)(H4,170,171,173)/t83-,84-,85-,86?,87+,88+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,126-,127-,128?,129-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 445-60 (2002)
Article DOI: 10.1124/jpet.102.038075
BindingDB Entry DOI: 10.7270/Q2R78CSR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM86694
(N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyform...)Show InChI InChI=1S/C11H14ClN3O2/c12-10-7-9(13-8-14-16)1-2-11(10)15-3-5-17-6-4-15/h1-2,7-8,16H,3-6H2,(H,13,14) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 314: 77-85 (2005)
Article DOI: 10.1124/jpet.105.083964
BindingDB Entry DOI: 10.7270/Q2MW2FQQ |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50122872
(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)Show InChI InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation
Curated by PDSP Ki Database
| |
Eur J Pharmacol 423: 71-83 (2001)
Article DOI: 10.1016/s0014-2999(01)01087-1
BindingDB Entry DOI: 10.7270/Q23T9FSX |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50250019
(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H331N63O53S/c1-18-109(12)162(262-156(279)99-230-170(290)147(95-157(280)281)255-193(313)149(100-267)259-168(288)124(211)93-119-97-224-103-231-119)198(318)257-145(88-114-40-20-19-21-41-114)191(311)266-163(113(16)270)199(319)258-148(96-158(282)283)190(310)261-151(102-269)194(314)253-144(92-118-59-67-123(274)68-60-118)188(308)260-150(101-268)192(312)243-134(51-38-83-227-202(220)221)180(300)251-142(90-116-55-63-121(272)64-56-116)186(306)242-132(49-36-81-225-200(216)217)176(296)237-127(44-24-31-76-206)173(293)245-137(70-72-153(213)276)182(302)246-138(73-85-320-17)171(291)233-112(15)167(287)263-159(106(6)7)195(315)247-130(47-27-34-79-209)175(295)238-129(46-26-33-78-208)177(297)252-143(91-117-57-65-122(273)66-58-117)187(307)249-140(87-105(4)5)184(304)234-110(13)165(285)232-111(14)166(286)264-160(107(8)9)197(317)256-139(86-104(2)3)169(289)229-98-155(278)235-126(43-23-30-75-205)172(292)239-133(50-37-82-226-201(218)219)179(299)250-141(89-115-53-61-120(271)62-54-115)185(305)241-128(45-25-32-77-207)174(294)244-136(69-71-152(212)275)181(301)240-135(52-39-84-228-203(222)223)183(303)265-161(108(10)11)196(316)248-131(48-28-35-80-210)178(298)254-146(94-154(214)277)189(309)236-125(164(215)284)42-22-29-74-204/h19-21,40-41,53-68,97,103-113,124-151,159-163,267-274H,18,22-39,42-52,69-96,98-102,204-211H2,1-17H3,(H2,212,275)(H2,213,276)(H2,214,277)(H2,215,284)(H,224,231)(H,229,289)(H,230,290)(H,232,285)(H,233,291)(H,234,304)(H,235,278)(H,236,309)(H,237,296)(H,238,295)(H,239,292)(H,240,301)(H,241,305)(H,242,306)(H,243,312)(H,244,294)(H,245,293)(H,246,302)(H,247,315)(H,248,316)(H,249,307)(H,250,299)(H,251,300)(H,252,297)(H,253,314)(H,254,298)(H,255,313)(H,256,317)(H,257,318)(H,258,319)(H,259,288)(H,260,308)(H,261,310)(H,262,279)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,280,281)(H,282,283)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t109-,110-,111-,112-,113+,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College
Curated by ChEMBL
| Assay Description
Displacement of [125I]PACAP1-27 from human recombinant PAC1 receptor expressed in CHO cells measured after 120 mins by scintillation counting method |
Bioorg Med Chem 25: 471-482 (2017)
Article DOI: 10.1016/j.bmc.2016.11.014
BindingDB Entry DOI: 10.7270/Q2CF9S3S |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50250019
(CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H331N63O53S/c1-18-109(12)162(262-156(279)99-230-170(290)147(95-157(280)281)255-193(313)149(100-267)259-168(288)124(211)93-119-97-224-103-231-119)198(318)257-145(88-114-40-20-19-21-41-114)191(311)266-163(113(16)270)199(319)258-148(96-158(282)283)190(310)261-151(102-269)194(314)253-144(92-118-59-67-123(274)68-60-118)188(308)260-150(101-268)192(312)243-134(51-38-83-227-202(220)221)180(300)251-142(90-116-55-63-121(272)64-56-116)186(306)242-132(49-36-81-225-200(216)217)176(296)237-127(44-24-31-76-206)173(293)245-137(70-72-153(213)276)182(302)246-138(73-85-320-17)171(291)233-112(15)167(287)263-159(106(6)7)195(315)247-130(47-27-34-79-209)175(295)238-129(46-26-33-78-208)177(297)252-143(91-117-57-65-122(273)66-58-117)187(307)249-140(87-105(4)5)184(304)234-110(13)165(285)232-111(14)166(286)264-160(107(8)9)197(317)256-139(86-104(2)3)169(289)229-98-155(278)235-126(43-23-30-75-205)172(292)239-133(50-37-82-226-201(218)219)179(299)250-141(89-115-53-61-120(271)62-54-115)185(305)241-128(45-25-32-77-207)174(294)244-136(69-71-152(212)275)181(301)240-135(52-39-84-228-203(222)223)183(303)265-161(108(10)11)196(316)248-131(48-28-35-80-210)178(298)254-146(94-154(214)277)189(309)236-125(164(215)284)42-22-29-74-204/h19-21,40-41,53-68,97,103-113,124-151,159-163,267-274H,18,22-39,42-52,69-96,98-102,204-211H2,1-17H3,(H2,212,275)(H2,213,276)(H2,214,277)(H2,215,284)(H,224,231)(H,229,289)(H,230,290)(H,232,285)(H,233,291)(H,234,304)(H,235,278)(H,236,309)(H,237,296)(H,238,295)(H,239,292)(H,240,301)(H,241,305)(H,242,306)(H,243,312)(H,244,294)(H,245,293)(H,246,302)(H,247,315)(H,248,316)(H,249,307)(H,250,299)(H,251,300)(H,252,297)(H,253,314)(H,254,298)(H,255,313)(H,256,317)(H,257,318)(H,258,319)(H,259,288)(H,260,308)(H,261,310)(H,262,279)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,280,281)(H,282,283)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t109-,110-,111-,112-,113+,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Binding affinity to human VPAC1 receptor by radioligand displacement assay |
Bioorg Med Chem 21: 2764-71 (2013)
Article DOI: 10.1016/j.bmc.2013.03.016
BindingDB Entry DOI: 10.7270/Q2N87C5Q |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50208990
(CHEMBL3884667)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O |r| Show InChI InChI=1S/C148H240N44O42/c1-19-76(14)116(144(232)183-98(56-73(8)9)132(220)174-94(119(157)207)61-109(154)200)190-141(229)107(68-194)187-136(224)103(63-111(156)202)180-133(221)97(55-72(6)7)177-134(222)99(58-82-38-42-85(197)43-39-82)178-126(214)89(34-24-27-49-150)169-124(212)90(35-25-28-50-151)172-142(230)114(74(10)11)188-120(208)77(15)166-129(217)95(53-70(2)3)175-128(216)93(46-47-108(153)199)171-123(211)88(33-23-26-48-149)168-125(213)91(36-29-51-163-147(158)159)170-131(219)96(54-71(4)5)176-127(215)92(37-30-52-164-148(160)161)173-145(233)117(79(17)195)191-138(226)100(59-83-40-44-86(198)45-41-83)179-135(223)102(62-110(155)201)181-137(225)105(65-113(205)206)185-146(234)118(80(18)196)192-139(227)101(57-81-31-21-20-22-32-81)184-143(231)115(75(12)13)189-121(209)78(16)167-130(218)104(64-112(203)204)182-140(228)106(67-193)186-122(210)87(152)60-84-66-162-69-165-84/h20-22,31-32,38-45,66,69-80,87-107,114-118,193-198H,19,23-30,33-37,46-65,67-68,149-152H2,1-18H3,(H2,153,199)(H2,154,200)(H2,155,201)(H2,156,202)(H2,157,207)(H,162,165)(H,166,217)(H,167,218)(H,168,213)(H,169,212)(H,170,219)(H,171,211)(H,172,230)(H,173,233)(H,174,220)(H,175,216)(H,176,215)(H,177,222)(H,178,214)(H,179,223)(H,180,221)(H,181,225)(H,182,228)(H,183,232)(H,184,231)(H,185,234)(H,186,210)(H,187,224)(H,188,208)(H,189,209)(H,190,229)(H,191,226)(H,192,227)(H,203,204)(H,205,206)(H4,158,159,163)(H4,160,161,164)/t76-,77-,78-,79+,80+,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,114-,115-,116-,117-,118-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College
Curated by ChEMBL
| Assay Description
Displacement of [125I]VIP from human recombinant VPAC1 receptor expressed in CHO cells measured after 60 mins by scintillation counting method |
Bioorg Med Chem 25: 471-482 (2017)
Article DOI: 10.1016/j.bmc.2016.11.014
BindingDB Entry DOI: 10.7270/Q2CF9S3S |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50435130
(CHEMBL1893324)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O Show InChI InChI=1S/C147H238N44O42S/c1-18-75(12)115(143(231)182-97(56-72(6)7)131(219)174-94(118(156)206)61-108(153)199)189-140(228)106(68-193)186-135(223)102(63-110(155)201)179-132(220)96(55-71(4)5)176-133(221)98(58-81-37-41-84(196)42-38-81)177-126(214)88(33-23-26-49-149)168-124(212)89(34-24-27-50-150)172-141(229)113(73(8)9)187-119(207)76(13)165-122(210)93(47-53-234-17)171-128(216)92(45-46-107(152)198)170-123(211)87(32-22-25-48-148)167-125(213)90(35-28-51-162-146(157)158)169-130(218)95(54-70(2)3)175-127(215)91(36-29-52-163-147(159)160)173-144(232)116(78(15)194)190-137(225)99(59-82-39-43-85(197)44-40-82)178-134(222)101(62-109(154)200)180-136(224)104(65-112(204)205)184-145(233)117(79(16)195)191-138(226)100(57-80-30-20-19-21-31-80)183-142(230)114(74(10)11)188-120(208)77(14)166-129(217)103(64-111(202)203)181-139(227)105(67-192)185-121(209)86(151)60-83-66-161-69-164-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,192-197H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,198)(H2,153,199)(H2,154,200)(H2,155,201)(H2,156,206)(H,161,164)(H,165,210)(H,166,217)(H,167,213)(H,168,212)(H,169,218)(H,170,211)(H,171,216)(H,172,229)(H,173,232)(H,174,219)(H,175,215)(H,176,221)(H,177,214)(H,178,222)(H,179,220)(H,180,224)(H,181,227)(H,182,231)(H,183,230)(H,184,233)(H,185,209)(H,186,223)(H,187,207)(H,188,208)(H,189,228)(H,190,225)(H,191,226)(H,202,203)(H,204,205)(H4,157,158,162)(H4,159,160,163)/t75-,76-,77-,78+,79+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,113-,114-,115-,116-,117-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College
Curated by ChEMBL
| Assay Description
Displacement of [125I]VIP from human recombinant VIP1 receptor expressed in CHO cells |
Bioorg Med Chem 24: 1793-810 (2016)
Article DOI: 10.1016/j.bmc.2016.03.006
BindingDB Entry DOI: 10.7270/Q2J67JS7 |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50435130
(CHEMBL1893324)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O Show InChI InChI=1S/C147H238N44O42S/c1-18-75(12)115(143(231)182-97(56-72(6)7)131(219)174-94(118(156)206)61-108(153)199)189-140(228)106(68-193)186-135(223)102(63-110(155)201)179-132(220)96(55-71(4)5)176-133(221)98(58-81-37-41-84(196)42-38-81)177-126(214)88(33-23-26-49-149)168-124(212)89(34-24-27-50-150)172-141(229)113(73(8)9)187-119(207)76(13)165-122(210)93(47-53-234-17)171-128(216)92(45-46-107(152)198)170-123(211)87(32-22-25-48-148)167-125(213)90(35-28-51-162-146(157)158)169-130(218)95(54-70(2)3)175-127(215)91(36-29-52-163-147(159)160)173-144(232)116(78(15)194)190-137(225)99(59-82-39-43-85(197)44-40-82)178-134(222)101(62-109(154)200)180-136(224)104(65-112(204)205)184-145(233)117(79(16)195)191-138(226)100(57-80-30-20-19-21-31-80)183-142(230)114(74(10)11)188-120(208)77(14)166-129(217)103(64-111(202)203)181-139(227)105(67-192)185-121(209)86(151)60-83-66-161-69-164-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,192-197H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,198)(H2,153,199)(H2,154,200)(H2,155,201)(H2,156,206)(H,161,164)(H,165,210)(H,166,217)(H,167,213)(H,168,212)(H,169,218)(H,170,211)(H,171,216)(H,172,229)(H,173,232)(H,174,219)(H,175,215)(H,176,221)(H,177,214)(H,178,222)(H,179,220)(H,180,224)(H,181,227)(H,182,231)(H,183,230)(H,184,233)(H,185,209)(H,186,223)(H,187,207)(H,188,208)(H,189,228)(H,190,225)(H,191,226)(H,202,203)(H,204,205)(H4,157,158,162)(H4,159,160,163)/t75-,76-,77-,78+,79+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,113-,114-,115-,116-,117-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Binding affinity to human VPAC1 receptor by radioligand displacement assay |
Bioorg Med Chem 21: 2764-71 (2013)
Article DOI: 10.1016/j.bmc.2013.03.016
BindingDB Entry DOI: 10.7270/Q2N87C5Q |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50435130
(CHEMBL1893324)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O Show InChI InChI=1S/C147H238N44O42S/c1-18-75(12)115(143(231)182-97(56-72(6)7)131(219)174-94(118(156)206)61-108(153)199)189-140(228)106(68-193)186-135(223)102(63-110(155)201)179-132(220)96(55-71(4)5)176-133(221)98(58-81-37-41-84(196)42-38-81)177-126(214)88(33-23-26-49-149)168-124(212)89(34-24-27-50-150)172-141(229)113(73(8)9)187-119(207)76(13)165-122(210)93(47-53-234-17)171-128(216)92(45-46-107(152)198)170-123(211)87(32-22-25-48-148)167-125(213)90(35-28-51-162-146(157)158)169-130(218)95(54-70(2)3)175-127(215)91(36-29-52-163-147(159)160)173-144(232)116(78(15)194)190-137(225)99(59-82-39-43-85(197)44-40-82)178-134(222)101(62-109(154)200)180-136(224)104(65-112(204)205)184-145(233)117(79(16)195)191-138(226)100(57-80-30-20-19-21-31-80)183-142(230)114(74(10)11)188-120(208)77(14)166-129(217)103(64-111(202)203)181-139(227)105(67-192)185-121(209)86(151)60-83-66-161-69-164-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,192-197H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,198)(H2,153,199)(H2,154,200)(H2,155,201)(H2,156,206)(H,161,164)(H,165,210)(H,166,217)(H,167,213)(H,168,212)(H,169,218)(H,170,211)(H,171,216)(H,172,229)(H,173,232)(H,174,219)(H,175,215)(H,176,221)(H,177,214)(H,178,222)(H,179,220)(H,180,224)(H,181,227)(H,182,231)(H,183,230)(H,184,233)(H,185,209)(H,186,223)(H,187,207)(H,188,208)(H,189,228)(H,190,225)(H,191,226)(H,202,203)(H,204,205)(H4,157,158,162)(H4,159,160,163)/t75-,76-,77-,78+,79+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,113-,114-,115-,116-,117-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Binding affinity to human VPAC1 receptor by radioligand displacement assay |
Eur J Med Chem 63: 85-94 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.044
BindingDB Entry DOI: 10.7270/Q2JH3NKC |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM392076
(US10301272, Example 7/9)Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)N[C@H]2C[C@@H](C2)C(O)=O)c2ccccc12 |r,wU:27.28,wD:29.33,(8.76,1.15,;7.67,.06,;6.19,.46,;7.28,1.55,;8.07,-1.42,;6.98,-2.51,;6.59,-4,;8.07,-3.6,;5.5,-2.11,;5.1,-.63,;3.61,-.23,;2.52,-1.32,;1.03,-.92,;.56,.55,;-.98,.55,;-1.46,-.92,;-.21,-1.82,;-.21,-3.36,;-1.55,-4.13,;-2.88,-3.36,;-4.21,-4.13,;-4.21,-5.67,;-2.88,-6.44,;-1.55,-5.67,;-2.07,1.64,;-1.67,3.12,;-3.56,1.24,;-4.65,2.33,;-6.19,2.33,;-6.19,3.87,;-4.65,3.87,;-7.28,4.96,;-6.88,6.44,;-8.76,4.56,;2.92,-2.8,;1.83,-3.89,;2.23,-5.38,;3.72,-5.78,;4.81,-4.69,;4.41,-3.2,)| Show InChI InChI=1S/C30H37N3O5S2/c1-30(2,3)33-40(37,38)25-14-13-23(21-11-7-8-12-22(21)25)26-24(15-18-9-5-4-6-10-18)32-28(39-26)27(34)31-20-16-19(17-20)29(35)36/h7-8,11-14,18-20,33H,4-6,9-10,15-17H2,1-3H3,(H,31,34)(H,35,36)/t19-,20- | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
Phenex Pharmaceuticals AG
Curated by ChEMBL
| Assay Description
Displacement of [125I]VIP from human recombinant VPAC1 receptor after 60 mins by scintillation counting analysis |
Bioorg Med Chem Lett 28: 1446-1455 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.093
BindingDB Entry DOI: 10.7270/Q27W6FPC |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50250018
(CHEMBL524852 | PACAP27)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.26,12.16,4.4,48.49,49.52,63.64,81.83,98.100,121.124,139.142,152.155,168.171,189.193,202.207,214.218,wD:20.22,2.2,37.37,55.56,69.70,87.89,110.113,130.133,147.151,159.162,177.180,197.202,207.211,(2.22,-11.33,;2.22,-12.87,;3.55,-13.64,;4.88,-12.87,;3.55,-15.18,;2.22,-15.95,;.88,-15.18,;.88,-13.64,;-.45,-15.95,;-1.79,-15.18,;-3.12,-15.95,;-3.12,-17.49,;-4.45,-15.18,;-4.45,-13.64,;-3.12,-12.87,;-1.79,-13.64,;-3.12,-11.33,;-5.79,-15.95,;-7.12,-15.18,;-7.12,-13.64,;-8.45,-15.95,;-8.45,-17.49,;-7.12,-18.26,;-9.79,-15.18,;-11.12,-15.95,;-11.12,-17.49,;-12.45,-15.18,;-13.79,-15.95,;-12.45,-13.64,;-11.12,-12.87,;-9.71,-13.5,;-8.68,-12.35,;-9.45,-11.01,;-10.96,-11.33,;4.88,-15.95,;4.88,-17.49,;6.22,-15.18,;7.55,-15.95,;7.55,-17.49,;8.88,-18.26,;10.22,-17.49,;11.56,-18.26,;11.56,-19.8,;10.22,-20.58,;8.88,-19.8,;8.88,-15.18,;8.88,-13.64,;10.22,-15.95,;11.55,-15.18,;11.55,-13.64,;10.22,-12.87,;12.89,-12.87,;12.89,-15.95,;12.89,-17.49,;14.22,-15.18,;15.55,-15.95,;15.55,-17.49,;16.89,-18.26,;18.22,-17.49,;16.89,-19.8,;16.89,-15.18,;16.89,-13.64,;18.22,-15.95,;19.55,-15.18,;19.55,-13.64,;20.89,-12.87,;20.89,-15.95,;20.89,-17.49,;22.22,-15.18,;23.55,-15.95,;23.55,-17.49,;24.89,-18.26,;26.23,-17.49,;27.57,-18.26,;27.57,-19.8,;28.9,-20.57,;26.23,-20.58,;24.89,-19.8,;24.89,-15.18,;24.89,-13.64,;26.22,-15.95,;27.56,-15.18,;27.56,-13.64,;28.89,-12.87,;28.89,-15.95,;28.89,-17.49,;30.22,-15.18,;31.56,-15.95,;31.56,-17.49,;32.89,-18.26,;32.89,-19.8,;34.22,-20.57,;34.22,-22.11,;32.89,-22.88,;35.56,-22.88,;32.89,-15.18,;32.89,-13.64,;34.22,-15.95,;35.56,-15.18,;35.56,-13.64,;36.89,-12.87,;38.23,-13.64,;39.57,-12.87,;39.57,-11.32,;40.9,-10.55,;38.23,-10.55,;36.89,-11.32,;36.89,-15.95,;36.89,-17.49,;38.23,-15.18,;39.56,-15.95,;39.56,-17.49,;40.89,-18.26,;40.89,-19.8,;42.23,-20.57,;42.23,-22.11,;40.89,-22.88,;43.56,-22.88,;40.89,-15.18,;40.89,-13.64,;42.23,-15.95,;43.56,-15.18,;43.56,-13.64,;44.89,-12.87,;44.89,-11.33,;46.23,-10.56,;46.23,-9.02,;44.89,-15.95,;44.89,-17.49,;46.23,-15.18,;47.56,-15.95,;47.56,-17.49,;48.89,-18.26,;48.89,-19.8,;47.56,-20.57,;50.23,-20.57,;48.89,-15.18,;48.89,-13.64,;50.23,-15.95,;51.56,-15.18,;51.56,-13.64,;52.9,-12.87,;52.9,-11.33,;54.23,-10.56,;52.9,-15.95,;52.9,-17.49,;54.23,-15.18,;55.56,-15.95,;55.56,-17.49,;56.9,-15.18,;56.9,-13.64,;58.23,-15.95,;59.56,-15.18,;59.56,-13.64,;60.9,-12.87,;58.23,-12.87,;60.9,-15.95,;60.9,-17.49,;62.23,-15.18,;63.57,-15.95,;63.57,-17.49,;64.9,-18.26,;64.9,-19.8,;66.23,-20.57,;66.23,-22.11,;64.9,-15.18,;64.9,-13.64,;66.23,-15.95,;67.57,-15.18,;67.57,-13.64,;68.9,-12.87,;68.9,-11.33,;70.23,-10.56,;70.23,-9.02,;68.9,-15.95,;68.9,-17.49,;70.23,-15.18,;71.57,-15.95,;71.57,-17.49,;72.9,-18.26,;74.24,-17.49,;75.58,-18.26,;75.58,-19.8,;76.91,-20.57,;74.24,-20.58,;72.9,-19.8,;72.9,-15.18,;72.9,-13.64,;74.23,-15.95,;75.57,-15.18,;75.57,-13.64,;76.9,-12.87,;76.9,-11.33,;78.24,-13.64,;76.9,-15.95,;76.9,-17.49,;78.24,-15.18,;79.57,-15.95,;79.57,-17.49,;80.9,-15.18,;80.9,-13.64,;82.24,-15.95,;83.57,-15.18,;83.57,-13.64,;84.9,-15.95,;84.9,-17.49,;86.24,-15.18,;87.57,-15.95,;87.57,-17.49,;88.91,-18.26,;86.24,-18.26,;88.91,-15.18,;88.91,-13.64,;90.24,-15.95,;91.57,-15.18,;91.57,-13.64,;92.91,-12.87,;92.91,-11.33,;94.24,-13.64,;92.91,-15.95,;94.24,-15.18,;92.91,-17.49,)| Show InChI InChI=1S/C142H224N40O39S/c1-16-75(10)113(179-108(191)66-156-120(201)102(63-109(192)193)173-135(216)104(67-183)176-119(200)88(146)62-84-65-153-70-157-84)139(220)174-101(58-80-28-18-17-19-29-80)133(214)182-114(79(14)186)140(221)175-103(64-110(194)195)132(213)178-106(69-185)136(217)172-100(61-83-39-45-87(189)46-40-83)131(212)177-105(68-184)134(215)164-93(34-27-54-155-142(151)152)126(207)170-98(59-81-35-41-85(187)42-36-81)129(210)163-92(33-26-53-154-141(149)150)124(205)161-89(30-20-23-50-143)122(203)165-94(47-48-107(147)190)127(208)166-95(49-55-222-15)121(202)159-78(13)118(199)180-111(73(6)7)137(218)167-91(32-22-25-52-145)123(204)162-90(31-21-24-51-144)125(206)171-99(60-82-37-43-86(188)44-38-82)130(211)169-97(57-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)138(219)168-96(115(148)196)56-71(2)3/h17-19,28-29,35-46,65,70-79,88-106,111-114,183-189H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,190)(H2,148,196)(H,153,157)(H,156,201)(H,158,197)(H,159,202)(H,160,209)(H,161,205)(H,162,204)(H,163,210)(H,164,215)(H,165,203)(H,166,208)(H,167,218)(H,168,219)(H,169,211)(H,170,207)(H,171,206)(H,172,217)(H,173,216)(H,174,220)(H,175,221)(H,176,200)(H,177,212)(H,178,213)(H,179,191)(H,180,199)(H,181,198)(H,182,214)(H,192,193)(H,194,195)(H4,149,150,154)(H4,151,152,155)/t75-,76-,77-,78-,79+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ du Qu£bec
Curated by ChEMBL
| Assay Description
Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysis |
Eur J Med Chem 104: 106-14 (2015)
Article DOI: 10.1016/j.ejmech.2015.09.017
BindingDB Entry DOI: 10.7270/Q2HH6P1F |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50498951
(CHEMBL3736134)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)C#Cc1ccc(F)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r| Show InChI InChI=1S/C150H227FN40O39S/c1-16-80(10)121(188-116(200)71-165-128(210)110(68-117(201)202)182-143(225)112(72-192)185-127(209)96(155)67-92-70-162-75-166-92)147(229)183-109(63-87-34-32-85(33-35-87)30-31-86-36-44-91(151)45-37-86)141(223)191-122(84(14)195)148(230)184-111(69-118(203)204)140(222)187-114(74-194)144(226)181-108(66-90-42-50-95(198)51-43-90)139(221)186-113(73-193)142(224)173-101(29-24-59-164-150(160)161)134(216)179-106(64-88-38-46-93(196)47-39-88)137(219)172-100(28-23-58-163-149(158)159)132(214)170-97(25-17-20-55-152)130(212)174-102(52-53-115(156)199)135(217)175-103(54-60-231-15)129(211)168-83(13)126(208)189-119(78(6)7)145(227)176-99(27-19-22-57-154)131(213)171-98(26-18-21-56-153)133(215)180-107(65-89-40-48-94(197)49-41-89)138(220)178-105(62-77(4)5)136(218)169-81(11)124(206)167-82(12)125(207)190-120(79(8)9)146(228)177-104(123(157)205)61-76(2)3/h32-51,70,75-84,96-114,119-122,192-198H,16-29,52-69,71-74,152-155H2,1-15H3,(H2,156,199)(H2,157,205)(H,162,166)(H,165,210)(H,167,206)(H,168,211)(H,169,218)(H,170,214)(H,171,213)(H,172,219)(H,173,224)(H,174,212)(H,175,217)(H,176,227)(H,177,228)(H,178,220)(H,179,216)(H,180,215)(H,181,226)(H,182,225)(H,183,229)(H,184,230)(H,185,209)(H,186,221)(H,187,222)(H,188,200)(H,189,208)(H,190,207)(H,191,223)(H,201,202)(H,203,204)(H4,158,159,163)(H4,160,161,164)/t80-,81-,82-,83-,84+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ du Qu£bec
Curated by ChEMBL
| Assay Description
Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysis |
Eur J Med Chem 104: 106-14 (2015)
Article DOI: 10.1016/j.ejmech.2015.09.017
BindingDB Entry DOI: 10.7270/Q2HH6P1F |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50498951
(CHEMBL3736134)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)C#Cc1ccc(F)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r| Show InChI InChI=1S/C150H227FN40O39S/c1-16-80(10)121(188-116(200)71-165-128(210)110(68-117(201)202)182-143(225)112(72-192)185-127(209)96(155)67-92-70-162-75-166-92)147(229)183-109(63-87-34-32-85(33-35-87)30-31-86-36-44-91(151)45-37-86)141(223)191-122(84(14)195)148(230)184-111(69-118(203)204)140(222)187-114(74-194)144(226)181-108(66-90-42-50-95(198)51-43-90)139(221)186-113(73-193)142(224)173-101(29-24-59-164-150(160)161)134(216)179-106(64-88-38-46-93(196)47-39-88)137(219)172-100(28-23-58-163-149(158)159)132(214)170-97(25-17-20-55-152)130(212)174-102(52-53-115(156)199)135(217)175-103(54-60-231-15)129(211)168-83(13)126(208)189-119(78(6)7)145(227)176-99(27-19-22-57-154)131(213)171-98(26-18-21-56-153)133(215)180-107(65-89-40-48-94(197)49-41-89)138(220)178-105(62-77(4)5)136(218)169-81(11)124(206)167-82(12)125(207)190-120(79(8)9)146(228)177-104(123(157)205)61-76(2)3/h32-51,70,75-84,96-114,119-122,192-198H,16-29,52-69,71-74,152-155H2,1-15H3,(H2,156,199)(H2,157,205)(H,162,166)(H,165,210)(H,167,206)(H,168,211)(H,169,218)(H,170,214)(H,171,213)(H,172,219)(H,173,224)(H,174,212)(H,175,217)(H,176,227)(H,177,228)(H,178,220)(H,179,216)(H,180,215)(H,181,226)(H,182,225)(H,183,229)(H,184,230)(H,185,209)(H,186,221)(H,187,222)(H,188,200)(H,189,208)(H,190,207)(H,191,223)(H,201,202)(H,203,204)(H4,158,159,163)(H4,160,161,164)/t80-,81-,82-,83-,84+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ du Qu£bec
Curated by ChEMBL
| Assay Description
Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysis |
Eur J Med Chem 104: 106-14 (2015)
Article DOI: 10.1016/j.ejmech.2015.09.017
BindingDB Entry DOI: 10.7270/Q2HH6P1F |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50498950
(CHEMBL3736230)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)C#Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r| Show InChI InChI=1S/C150H228N40O39S/c1-16-81(10)121(187-116(199)72-164-128(209)110(69-117(200)201)181-143(224)112(73-191)184-127(208)96(154)68-92-71-161-76-165-92)147(228)182-109(64-88-39-37-87(38-40-88)36-35-86-28-18-17-19-29-86)141(222)190-122(85(14)194)148(229)183-111(70-118(202)203)140(221)186-114(75-193)144(225)180-108(67-91-45-51-95(197)52-46-91)139(220)185-113(74-192)142(223)172-101(34-27-60-163-150(159)160)134(215)178-106(65-89-41-47-93(195)48-42-89)137(218)171-100(33-26-59-162-149(157)158)132(213)169-97(30-20-23-56-151)130(211)173-102(53-54-115(155)198)135(216)174-103(55-61-230-15)129(210)167-84(13)126(207)188-119(79(6)7)145(226)175-99(32-22-25-58-153)131(212)170-98(31-21-24-57-152)133(214)179-107(66-90-43-49-94(196)50-44-90)138(219)177-105(63-78(4)5)136(217)168-82(11)124(205)166-83(12)125(206)189-120(80(8)9)146(227)176-104(123(156)204)62-77(2)3/h17-19,28-29,37-52,71,76-85,96-114,119-122,191-197H,16,20-27,30-34,53-70,72-75,151-154H2,1-15H3,(H2,155,198)(H2,156,204)(H,161,165)(H,164,209)(H,166,205)(H,167,210)(H,168,217)(H,169,213)(H,170,212)(H,171,218)(H,172,223)(H,173,211)(H,174,216)(H,175,226)(H,176,227)(H,177,219)(H,178,215)(H,179,214)(H,180,225)(H,181,224)(H,182,228)(H,183,229)(H,184,208)(H,185,220)(H,186,221)(H,187,199)(H,188,207)(H,189,206)(H,190,222)(H,200,201)(H,202,203)(H4,157,158,162)(H4,159,160,163)/t81-,82-,83-,84-,85+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ du Qu£bec
Curated by ChEMBL
| Assay Description
Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysis |
Eur J Med Chem 104: 106-14 (2015)
Article DOI: 10.1016/j.ejmech.2015.09.017
BindingDB Entry DOI: 10.7270/Q2HH6P1F |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50200209
(CHEMBL219499)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O |r,wU:4.4,121.124,63.64,139.142,12.16,152.155,81.83,168.171,189.193,98.100,48.49,202.207,26.26,49.52,214.218,wD:110.113,55.56,130.133,2.2,69.70,147.151,37.37,159.162,177.180,87.89,197.202,20.22,207.211,(-37.66,-5.64,;-37.66,-7.18,;-36.32,-7.95,;-34.99,-7.18,;-36.32,-9.49,;-37.66,-10.26,;-38.99,-9.49,;-38.99,-7.95,;-40.33,-10.26,;-41.67,-9.49,;-42.98,-10.26,;-42.98,-11.8,;-44.32,-9.49,;-44.32,-7.95,;-42.98,-7.18,;-41.65,-7.94,;-42.99,-5.63,;-45.66,-10.26,;-46.99,-9.49,;-46.99,-7.95,;-48.33,-10.26,;-48.33,-11.8,;-46.99,-12.57,;-49.66,-9.49,;-51,-10.26,;-51,-11.8,;-52.33,-9.49,;-53.65,-10.26,;-52.33,-7.95,;-51,-7.18,;-49.53,-7.67,;-48.61,-6.44,;-49.49,-5.18,;-50.96,-5.63,;-34.99,-10.26,;-34.99,-11.8,;-33.65,-9.49,;-32.32,-10.26,;-32.32,-11.8,;-30.98,-12.57,;-30.99,-14.11,;-29.65,-14.88,;-28.32,-14.11,;-28.33,-12.56,;-29.66,-11.8,;-30.98,-9.49,;-30.98,-7.95,;-29.66,-10.26,;-28.33,-9.49,;-28.33,-7.95,;-29.66,-7.18,;-26.99,-7.18,;-26.99,-10.26,;-26.99,-11.8,;-25.65,-9.49,;-24.32,-10.26,;-24.32,-11.8,;-22.98,-12.57,;-22.99,-14.11,;-21.65,-11.8,;-22.98,-9.49,;-22.98,-7.95,;-21.65,-10.26,;-20.31,-9.49,;-20.31,-7.95,;-18.99,-7.18,;-18.99,-10.26,;-18.99,-11.8,;-17.66,-9.49,;-16.32,-10.26,;-16.32,-11.8,;-14.99,-12.57,;-14.99,-14.11,;-13.66,-14.88,;-12.32,-14.11,;-10.98,-14.88,;-12.33,-12.56,;-13.65,-11.8,;-14.99,-9.49,;-14.99,-7.95,;-13.65,-10.26,;-12.31,-9.49,;-12.31,-7.95,;-10.97,-7.18,;-10.97,-10.26,;-10.97,-11.8,;-9.64,-9.49,;-8.31,-10.26,;-8.31,-11.8,;-6.97,-12.57,;-6.97,-14.11,;-5.64,-14.88,;-5.64,-16.42,;-4.31,-17.19,;-6.97,-17.19,;-6.97,-9.49,;-6.97,-7.95,;-5.64,-10.26,;-4.31,-9.49,;-4.31,-7.95,;-2.97,-7.18,;-1.64,-7.96,;-.31,-7.19,;-.31,-5.65,;1.02,-4.88,;-1.65,-4.88,;-2.98,-5.65,;-2.97,-10.26,;-2.97,-11.8,;-1.64,-9.49,;-.3,-10.26,;-.3,-11.8,;1.03,-12.57,;1.03,-14.11,;2.36,-14.88,;2.36,-16.42,;3.7,-17.19,;1.03,-17.19,;1.03,-9.49,;1.03,-7.95,;2.36,-10.26,;3.7,-9.49,;3.7,-7.95,;5.03,-7.18,;5.03,-5.64,;6.36,-4.87,;6.36,-3.33,;5.03,-10.26,;5.03,-11.8,;6.36,-9.49,;7.7,-10.26,;7.7,-11.8,;9.03,-12.57,;9.03,-14.11,;7.7,-14.88,;10.36,-14.88,;9.03,-9.49,;9.03,-7.95,;10.36,-10.26,;11.7,-9.49,;11.7,-7.95,;13.03,-7.18,;13.03,-5.64,;14.37,-4.87,;13.03,-10.26,;13.03,-11.8,;14.37,-9.49,;15.7,-10.26,;15.7,-11.8,;17.03,-9.49,;17.03,-7.95,;18.37,-10.26,;19.7,-9.49,;19.7,-7.95,;21.03,-7.18,;18.37,-7.18,;21.03,-10.26,;21.03,-11.8,;22.37,-9.49,;23.7,-10.26,;23.7,-11.8,;25.04,-12.57,;25.04,-14.11,;26.37,-14.88,;26.37,-16.42,;25.04,-9.49,;25.04,-7.95,;26.37,-10.26,;27.7,-9.49,;27.7,-7.95,;29.04,-7.18,;29.04,-5.64,;30.37,-4.87,;30.37,-3.33,;29.04,-10.26,;29.04,-11.8,;30.37,-9.49,;31.7,-10.26,;31.7,-11.8,;33.04,-12.57,;33.03,-14.11,;34.36,-14.88,;35.7,-14.11,;37.03,-14.88,;35.69,-12.56,;34.37,-11.8,;33.04,-9.49,;33.04,-7.95,;34.37,-10.26,;35.7,-9.49,;35.7,-7.95,;37.04,-7.18,;37.04,-5.64,;38.37,-7.95,;37.04,-10.26,;37.04,-11.8,;38.37,-9.49,;39.71,-10.26,;39.71,-11.8,;41.04,-9.49,;41.04,-7.95,;42.37,-10.26,;43.71,-9.49,;43.71,-7.95,;45.04,-10.26,;45.04,-11.8,;46.37,-9.49,;47.71,-10.26,;47.71,-11.8,;46.37,-12.57,;49.04,-12.57,;49.04,-9.49,;49.04,-7.95,;50.37,-10.26,;51.71,-9.49,;51.71,-7.95,;53.04,-7.18,;53.04,-5.64,;54.38,-7.95,;53.04,-10.26,;54.38,-9.49,;53.04,-11.8,)| Show InChI InChI=1S/C142H223N39O40S/c1-16-75(10)113(178-108(190)66-155-119(199)101(63-109(191)192)171-134(214)104(67-182)175-118(198)88(146)62-84-65-152-70-156-84)138(218)172-100(58-80-28-18-17-19-29-80)132(212)181-114(79(14)185)139(219)173-102(64-110(193)194)131(211)177-106(69-184)135(215)170-99(61-83-39-45-87(188)46-40-83)130(210)176-105(68-183)133(213)163-93(34-27-54-154-142(150)151)125(205)168-97(59-81-35-41-85(186)42-36-81)128(208)162-92(33-26-53-153-141(148)149)123(203)160-89(30-20-23-50-143)121(201)164-94(47-48-107(147)189)126(206)165-95(49-55-222-15)120(200)158-78(13)117(197)179-111(73(6)7)136(216)166-91(32-22-25-52-145)122(202)161-90(31-21-24-51-144)124(204)169-98(60-82-37-43-86(187)44-38-82)129(209)167-96(56-71(2)3)127(207)159-76(11)115(195)157-77(12)116(196)180-112(74(8)9)137(217)174-103(140(220)221)57-72(4)5/h17-19,28-29,35-46,65,70-79,88-106,111-114,182-188H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,189)(H,152,156)(H,155,199)(H,157,195)(H,158,200)(H,159,207)(H,160,203)(H,161,202)(H,162,208)(H,163,213)(H,164,201)(H,165,206)(H,166,216)(H,167,209)(H,168,205)(H,169,204)(H,170,215)(H,171,214)(H,172,218)(H,173,219)(H,174,217)(H,175,198)(H,176,210)(H,177,211)(H,178,190)(H,179,197)(H,180,196)(H,181,212)(H,191,192)(H,193,194)(H,220,221)(H4,148,149,153)(H4,150,151,154)/t75-,76-,77-,78-,79+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation
Curated by ChEMBL
| Assay Description
Displacement of [125I]PACAP27 from human VPAC1 receptor expressed in CHO cells |
J Med Chem 49: 7545-8 (2006)
Article DOI: 10.1021/jm0609059
BindingDB Entry DOI: 10.7270/Q2VD708R |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50498950
(CHEMBL3736230)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)C#Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r| Show InChI InChI=1S/C150H228N40O39S/c1-16-81(10)121(187-116(199)72-164-128(209)110(69-117(200)201)181-143(224)112(73-191)184-127(208)96(154)68-92-71-161-76-165-92)147(228)182-109(64-88-39-37-87(38-40-88)36-35-86-28-18-17-19-29-86)141(222)190-122(85(14)194)148(229)183-111(70-118(202)203)140(221)186-114(75-193)144(225)180-108(67-91-45-51-95(197)52-46-91)139(220)185-113(74-192)142(223)172-101(34-27-60-163-150(159)160)134(215)178-106(65-89-41-47-93(195)48-42-89)137(218)171-100(33-26-59-162-149(157)158)132(213)169-97(30-20-23-56-151)130(211)173-102(53-54-115(155)198)135(216)174-103(55-61-230-15)129(210)167-84(13)126(207)188-119(79(6)7)145(226)175-99(32-22-25-58-153)131(212)170-98(31-21-24-57-152)133(214)179-107(66-90-43-49-94(196)50-44-90)138(219)177-105(63-78(4)5)136(217)168-82(11)124(205)166-83(12)125(206)189-120(80(8)9)146(227)176-104(123(156)204)62-77(2)3/h17-19,28-29,37-52,71,76-85,96-114,119-122,191-197H,16,20-27,30-34,53-70,72-75,151-154H2,1-15H3,(H2,155,198)(H2,156,204)(H,161,165)(H,164,209)(H,166,205)(H,167,210)(H,168,217)(H,169,213)(H,170,212)(H,171,218)(H,172,223)(H,173,211)(H,174,216)(H,175,226)(H,176,227)(H,177,219)(H,178,215)(H,179,214)(H,180,225)(H,181,224)(H,182,228)(H,183,229)(H,184,208)(H,185,220)(H,186,221)(H,187,199)(H,188,207)(H,189,206)(H,190,222)(H,200,201)(H,202,203)(H4,157,158,162)(H4,159,160,163)/t81-,82-,83-,84-,85+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,119-,120-,121-,122-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ du Qu£bec
Curated by ChEMBL
| Assay Description
Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysis |
Eur J Med Chem 104: 106-14 (2015)
Article DOI: 10.1016/j.ejmech.2015.09.017
BindingDB Entry DOI: 10.7270/Q2HH6P1F |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50250074
(CHEMBL507480 | [Bip6]PACAP27)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.26,12.16,4.4,54.56,55.59,69.71,87.90,104.107,127.131,145.149,158.162,174.178,195.200,208.214,220.225,wD:20.22,2.2,37.37,61.63,75.77,93.96,116.120,136.140,153.158,165.169,183.187,203.209,213.218,(4.93,2.23,;4.93,.69,;6.26,-.08,;7.6,.69,;6.26,-1.62,;4.93,-2.39,;3.6,-1.62,;3.6,-.08,;2.26,-2.39,;.93,-1.62,;-.4,-2.39,;-.4,-3.93,;-1.74,-1.62,;-1.74,-.08,;-.4,.69,;.93,-.08,;-.4,2.23,;-3.07,-2.39,;-4.4,-1.62,;-4.4,-.08,;-5.74,-2.39,;-5.74,-3.93,;-4.4,-4.7,;-7.07,-1.62,;-8.41,-2.39,;-8.41,-3.93,;-9.74,-1.62,;-11.07,-2.39,;-9.74,-.08,;-8.41,.69,;-6.99,.06,;-5.96,1.21,;-6.73,2.55,;-8.24,2.23,;7.6,-2.39,;7.6,-3.93,;8.93,-1.62,;10.27,-2.39,;10.27,-3.93,;11.6,-4.7,;11.6,-6.25,;12.94,-7.02,;14.28,-6.25,;14.28,-4.7,;12.94,-3.93,;15.61,-7.01,;15.61,-8.56,;16.95,-9.33,;18.29,-8.56,;18.28,-7,;16.94,-6.24,;11.6,-1.62,;11.6,-.08,;12.93,-2.39,;14.27,-1.62,;14.27,-.08,;12.93,.69,;15.6,.69,;15.6,-2.39,;15.6,-3.93,;16.93,-1.62,;18.27,-2.39,;18.27,-3.93,;19.6,-4.7,;20.93,-3.93,;19.6,-6.24,;19.6,-1.62,;19.6,-.08,;20.93,-2.39,;22.27,-1.62,;22.27,-.08,;23.6,.69,;23.6,-2.39,;23.6,-3.93,;24.94,-1.62,;26.27,-2.39,;26.27,-3.93,;27.6,-4.7,;28.94,-3.93,;30.28,-4.7,;30.28,-6.25,;31.61,-7.02,;28.94,-7.02,;27.6,-6.25,;27.6,-1.62,;27.6,-.08,;28.94,-2.39,;30.27,-1.62,;30.27,-.08,;31.6,.69,;31.6,-2.39,;31.6,-3.93,;32.94,-1.62,;34.27,-2.39,;34.27,-3.93,;35.61,-4.7,;35.61,-6.24,;36.94,-7.01,;36.94,-8.55,;35.61,-9.32,;38.27,-9.32,;35.61,-1.62,;35.61,-.08,;36.94,-2.39,;38.27,-1.62,;38.27,-.08,;39.61,.69,;40.94,-.08,;42.28,.69,;42.28,2.24,;43.62,3.01,;40.94,3.01,;39.61,2.24,;39.61,-2.39,;39.61,-3.93,;40.94,-1.62,;42.27,-2.39,;42.27,-3.93,;43.61,-4.7,;43.61,-6.24,;44.94,-7.01,;44.94,-8.55,;43.61,-9.32,;46.27,-9.32,;43.61,-1.62,;43.61,-.08,;44.94,-2.39,;46.27,-1.62,;46.27,-.08,;47.61,.69,;47.61,2.23,;48.94,3,;48.94,4.54,;47.61,-2.39,;47.61,-3.93,;48.94,-1.62,;50.28,-2.39,;50.28,-3.93,;51.61,-4.7,;51.61,-6.24,;50.28,-7.01,;52.94,-7.01,;51.61,-1.62,;51.61,-.08,;52.94,-2.39,;54.28,-1.62,;54.28,-.08,;55.61,.69,;55.61,2.23,;56.94,3,;55.61,-2.39,;55.61,-3.93,;56.94,-1.62,;58.28,-2.39,;58.28,-3.93,;59.61,-1.62,;59.61,-.08,;60.94,-2.39,;62.28,-1.62,;62.28,-.08,;63.61,.69,;60.94,.69,;63.61,-2.39,;63.61,-3.93,;64.95,-1.62,;66.28,-2.39,;66.28,-3.93,;67.61,-4.7,;67.61,-6.24,;68.95,-7.01,;68.95,-8.55,;67.61,-1.62,;67.61,-.08,;68.95,-2.39,;70.28,-1.62,;70.28,-.08,;71.61,.69,;71.61,2.23,;72.95,3,;72.95,4.54,;71.61,-2.39,;71.61,-3.93,;72.95,-1.62,;74.28,-2.39,;74.28,-3.93,;75.61,-4.7,;76.95,-3.93,;78.29,-4.7,;78.29,-6.25,;79.63,-7.02,;76.95,-7.02,;75.61,-6.25,;75.61,-1.62,;75.61,-.08,;76.95,-2.39,;78.28,-1.62,;78.28,-.08,;79.62,.69,;79.62,2.23,;80.95,-.08,;79.62,-2.39,;79.62,-3.93,;80.95,-1.62,;82.28,-2.39,;82.28,-3.93,;83.62,-1.62,;83.62,-.08,;84.95,-2.39,;86.28,-1.62,;86.28,-.08,;87.62,-2.39,;87.62,-3.93,;88.95,-1.62,;90.29,-2.39,;90.29,-3.93,;91.62,-4.7,;88.95,-4.7,;91.62,-1.62,;91.62,-.08,;92.95,-2.39,;94.29,-1.62,;94.29,-.08,;95.62,.69,;95.62,2.23,;96.95,-.08,;95.62,-2.39,;96.95,-1.62,;95.62,-3.93,)| Show InChI InChI=1S/C148H228N40O39S/c1-16-79(10)119(185-114(197)70-162-126(207)108(67-115(198)199)179-141(222)110(71-189)182-125(206)94(152)66-90-69-159-74-163-90)145(226)180-107(62-84-35-43-89(44-36-84)88-28-18-17-19-29-88)139(220)188-120(83(14)192)146(227)181-109(68-116(200)201)138(219)184-112(73-191)142(223)178-106(65-87-41-49-93(195)50-42-87)137(218)183-111(72-190)140(221)170-99(34-27-58-161-148(157)158)132(213)176-104(63-85-37-45-91(193)46-38-85)135(216)169-98(33-26-57-160-147(155)156)130(211)167-95(30-20-23-54-149)128(209)171-100(51-52-113(153)196)133(214)172-101(53-59-228-15)127(208)165-82(13)124(205)186-117(77(6)7)143(224)173-97(32-22-25-56-151)129(210)168-96(31-21-24-55-150)131(212)177-105(64-86-39-47-92(194)48-40-86)136(217)175-103(61-76(4)5)134(215)166-80(11)122(203)164-81(12)123(204)187-118(78(8)9)144(225)174-102(121(154)202)60-75(2)3/h17-19,28-29,35-50,69,74-83,94-112,117-120,189-195H,16,20-27,30-34,51-68,70-73,149-152H2,1-15H3,(H2,153,196)(H2,154,202)(H,159,163)(H,162,207)(H,164,203)(H,165,208)(H,166,215)(H,167,211)(H,168,210)(H,169,216)(H,170,221)(H,171,209)(H,172,214)(H,173,224)(H,174,225)(H,175,217)(H,176,213)(H,177,212)(H,178,223)(H,179,222)(H,180,226)(H,181,227)(H,182,206)(H,183,218)(H,184,219)(H,185,197)(H,186,205)(H,187,204)(H,188,220)(H,198,199)(H,200,201)(H4,155,156,160)(H4,157,158,161)/t79-,80-,81-,82-,83+,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,117-,118-,119-,120-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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UniChem
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| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ du Qu£bec
Curated by ChEMBL
| Assay Description
Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysis |
Eur J Med Chem 104: 106-14 (2015)
Article DOI: 10.1016/j.ejmech.2015.09.017
BindingDB Entry DOI: 10.7270/Q2HH6P1F |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50365986
(CHEMBL1956427)Show InChI InChI=1S/C22H30O/c1-14(2)19-11-18(22(5,6)7)12-20(21(19)13-23)17-9-8-15(3)16(4)10-17/h8-12,14,23H,13H2,1-7H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50365985
(CHEMBL1956426)Show InChI InChI=1S/C20H25ClO/c1-13(2)17-10-15(20(3,4)5)11-18(19(17)12-22)14-7-6-8-16(21)9-14/h6-11,13,22H,12H2,1-5H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Homo sapiens (Human)) | BDBM50606528
(CHEMBL5219662)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](CCS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(C)C)C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O |r| | PDB
UniProtKB/SwissProt
antibodypedia
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UniChem
| Article
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| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01396
BindingDB Entry DOI: 10.7270/Q2RX9H5M |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366026
(CHEMBL1956425)Show InChI InChI=1S/C24H28O/c1-16(2)21-13-20(24(3,4)5)14-22(23(21)15-25)19-11-10-17-8-6-7-9-18(17)12-19/h6-14,16,25H,15H2,1-5H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366024
(CHEMBL1956413)Show InChI InChI=1S/C21H28OS/c1-14(2)18-11-16(21(3,4)5)12-19(20(18)13-22)15-8-7-9-17(10-15)23-6/h7-12,14,22H,13H2,1-6H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366025
(CHEMBL1956424)Show InChI InChI=1S/C24H28O/c1-16(2)21-13-18(24(3,4)5)14-22(23(21)15-25)20-12-8-10-17-9-6-7-11-19(17)20/h6-14,16,25H,15H2,1-5H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366023
(CHEMBL1956412)Show InChI InChI=1S/C21H28O2/c1-14(2)18-11-16(21(3,4)5)12-19(20(18)13-22)15-8-7-9-17(10-15)23-6/h7-12,14,22H,13H2,1-6H3 | KEGG
UniProtKB/SwissProt
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UniChem
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PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366022
(CHEMBL1956423)Show SMILES CC(C)c1cc(cc(c1CO)-c1cccc(c1)-c1ccccc1)C(C)(C)C Show InChI InChI=1S/C26H30O/c1-18(2)23-15-22(26(3,4)5)16-24(25(23)17-27)21-13-9-12-20(14-21)19-10-7-6-8-11-19/h6-16,18,27H,17H2,1-5H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366021
(CHEMBL1956422)Show InChI InChI=1S/C21H28O/c1-14(2)18-11-17(21(4,5)6)12-19(20(18)13-22)16-9-7-8-15(3)10-16/h7-12,14,22H,13H2,1-6H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366020
(CHEMBL1956421)Show InChI InChI=1S/C20H25ClO/c1-13(2)17-10-15(20(3,4)5)11-18(19(17)12-22)14-6-8-16(21)9-7-14/h6-11,13,22H,12H2,1-5H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50365996
(CHEMBL1956433)Show InChI InChI=1S/C18H18N2OS/c19-12-15-14-8-4-5-9-16(14)22-18(15)20-17(21)11-10-13-6-2-1-3-7-13/h1-3,6-7H,4-5,8-11H2,(H,20,21) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
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UniChem
Similars
| Article
PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366019
(CHEMBL1956420)Show InChI InChI=1S/C21H28O/c1-14(2)18-11-17(21(4,5)6)12-19(20(18)13-22)16-9-7-15(3)8-10-16/h7-12,14,22H,13H2,1-6H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366018
(CHEMBL1956419)Show SMILES CC(C)c1cc(cc(-c2cccc(c2)N(C)C)c1CO)C(C)(C)C Show InChI InChI=1S/C22H31NO/c1-15(2)19-12-17(22(3,4)5)13-20(21(19)14-24)16-9-8-10-18(11-16)23(6)7/h8-13,15,24H,14H2,1-7H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366017
(CHEMBL1956418)Show InChI InChI=1S/C20H26O/c1-14(2)17-11-16(20(3,4)5)12-18(19(17)13-21)15-9-7-6-8-10-15/h6-12,14,21H,13H2,1-5H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
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PC sid
UniChem
Similars
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PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366001
(CHEMBL1956438)Show InChI InChI=1S/C19H20N2O2S/c1-23-14-9-6-13(7-10-14)8-11-18(22)21-19-16(12-20)15-4-2-3-5-17(15)24-19/h6-7,9-10H,2-5,8,11H2,1H3,(H,21,22) | KEGG
UniProtKB/SwissProt
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CHEMBL
PC cid
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UniChem
Similars
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PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50365993
(CHEMBL1956432)Show InChI InChI=1S/C15H18N2OS/c16-9-12-11-7-3-4-8-13(11)19-15(12)17-14(18)10-5-1-2-6-10/h10H,1-8H2,(H,17,18) | KEGG
UniProtKB/SwissProt
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50365994
(CHEMBL396627)Show InChI InChI=1S/C16H20N2OS/c17-10-13-12-8-4-5-9-14(12)20-16(13)18-15(19)11-6-2-1-3-7-11/h11H,1-9H2,(H,18,19) | KEGG
UniProtKB/SwissProt
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PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50365999
(CHEMBL1956436)Show InChI InChI=1S/C19H20N2OS/c1-13-6-8-14(9-7-13)10-11-18(22)21-19-16(12-20)15-4-2-3-5-17(15)23-19/h6-9H,2-5,10-11H2,1H3,(H,21,22) | KEGG
UniProtKB/SwissProt
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366000
(CHEMBL1956437)Show InChI InChI=1S/C19H20N2O2S/c1-23-14-6-4-5-13(11-14)9-10-18(22)21-19-16(12-20)15-7-2-3-8-17(15)24-19/h4-6,11H,2-3,7-10H2,1H3,(H,21,22) | KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366016
(CHEMBL1956417)Show SMILES CC(C)c1cc(cc(c1CO)-c1ccc(cc1)-c1ccccc1)C(C)(C)C Show InChI InChI=1S/C26H30O/c1-18(2)23-15-22(26(3,4)5)16-24(25(23)17-27)21-13-11-20(12-14-21)19-9-7-6-8-10-19/h6-16,18,27H,17H2,1-5H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366015
(CHEMBL1956416)Show InChI InChI=1S/C20H25FO/c1-13(2)17-10-15(20(3,4)5)11-18(19(17)12-22)14-6-8-16(21)9-7-14/h6-11,13,22H,12H2,1-5H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
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UniChem
Patents
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| Article
PubMed
| n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50365998
(CHEMBL1956435)Show InChI InChI=1S/C19H20N2OS/c1-13-5-4-6-14(11-13)9-10-18(22)21-19-16(12-20)15-7-2-3-8-17(15)23-19/h4-6,11H,2-3,7-10H2,1H3,(H,21,22) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366014
(CHEMBL1956415)Show InChI InChI=1S/C21H28O2/c1-14(2)17-11-15(21(3,4)5)12-18(19(17)13-22)16-9-7-8-10-20(16)23-6/h7-12,14,22H,13H2,1-6H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366002
(CHEMBL1956439)Show InChI InChI=1S/C18H17ClN2OS/c19-13-8-5-12(6-9-13)7-10-17(22)21-18-15(11-20)14-3-1-2-4-16(14)23-18/h5-6,8-9H,1-4,7,10H2,(H,21,22) | KEGG
UniProtKB/SwissProt
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
Vasoactive intestinal polypeptide receptor 1
(Rattus norvegicus) | BDBM50366013
(CHEMBL1956414)Show InChI InChI=1S/C21H28O2/c1-14(2)18-11-16(21(3,4)5)12-19(20(18)13-22)15-7-9-17(23-6)10-8-15/h7-12,14,22H,13H2,1-6H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description
Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio... |
Bioorg Med Chem Lett 22: 2287-90 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.082
BindingDB Entry DOI: 10.7270/Q2Q240QR |
More data for this
Ligand-Target Pair | |
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