Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal/Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM24470 (7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem... | Bioorg Chem 70: 126-132 (2017) Article DOI: 10.1016/j.bioorg.2016.12.002 BindingDB Entry DOI: 10.7270/Q23X85HP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Epidermal/Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM222078 (6-Chloro-3-((2-(2,4-dichlorophenyl)imidazo[1,2-a]p...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem... | Bioorg Chem 70: 126-132 (2017) Article DOI: 10.1016/j.bioorg.2016.12.002 BindingDB Entry DOI: 10.7270/Q23X85HP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal/Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM222077 (6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem... | Bioorg Chem 70: 126-132 (2017) Article DOI: 10.1016/j.bioorg.2016.12.002 BindingDB Entry DOI: 10.7270/Q23X85HP | |||||||||||
More data for this Ligand-Target Pair |