Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM7458 (5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Punjabi University Curated by ChEMBL | Assay Description Inhibition of forskolin-stimulated CFTR (unknown origin) | Eur J Med Chem 84: 206-39 (2014) Article DOI: 10.1016/j.ejmech.2014.07.013 BindingDB Entry DOI: 10.7270/Q2GH9KMN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221982 (US9303035, 6) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221986 (US9303035, 8.0a) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221984 (US9303035, 7.0a) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221987 (US9303035, 8.1a) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221992 (US9303035, 12.2) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221983 (US9303035, 6.1) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221989 (US9303035, 11a) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221993 (US9303035, 12.4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221967 (US9303035, 2.9) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221990 (US9303035, 12) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221985 (US9303035, 7.1a) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221994 (US9303035, 12.5) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221970 (US9303035, 3.2) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221969 (US9303035, 3.1) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221952 (US9303035, 1.2) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.58 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221958 (US9303035, 1.26) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221996 (US9303035, 14) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.96 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221978 (US9303035, 4.1 | US9303035, 4.3) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221981 (US9303035, 5.1) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.24 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221995 (US9303035, 13) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.53 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50434312 (CHEMBL2386374) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of wild type human CFTR chloride conductance expressed in forskolin-stimulated rat FRT cells by short-circuit current analysis in presence... | ACS Med Chem Lett 4: 456-459 (2013) Article DOI: 10.1021/ml400069k BindingDB Entry DOI: 10.7270/Q29888DW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221978 (US9303035, 4.1 | US9303035, 4.3) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.23 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221934 (US9303035, 1.1) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.64 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221941 (US9303035, 1.9 | US9303035, 2.4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.98 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50343996 (2,4-dimethylpyrido[1,2-a]pyrimidin-5-ium-3-olate |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Joseph Fourier-Grenoble 1/CNRS Curated by ChEMBL | Assay Description Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assay | Eur J Med Chem 46: 1935-41 (2011) Article DOI: 10.1016/j.ejmech.2011.02.037 BindingDB Entry DOI: 10.7270/Q23R0T6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221991 (US9303035, 12.1) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.07 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221939 (US9303035, 1.7) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.42 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221941 (US9303035, 1.9 | US9303035, 2.4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221942 (US9303035, 1.10) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.37 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221964 (US9303035, 2.6) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.62 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50353351 (CHEMBL1831075) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human wild-type CFTR expressed in FRT cells assessed as inhibition of forskolin-induced short-circuit current by voltage clamp electrop... | J Med Chem 54: 5468-77 (2011) Article DOI: 10.1021/jm200505e BindingDB Entry DOI: 10.7270/Q2280809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221988 (US9303035, 9b) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.06 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221974 (US9303035, 3.6) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.26 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221944 (US9303035, 1.12) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221946 (US9303035, 1.14) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50343998 ((2S,3R,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University Joseph Fourier-Grenoble 1/CNRS Curated by ChEMBL | Assay Description Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assay | Eur J Med Chem 46: 1935-41 (2011) Article DOI: 10.1016/j.ejmech.2011.02.037 BindingDB Entry DOI: 10.7270/Q23R0T6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50343998 ((2S,3R,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University Joseph Fourier-Grenoble 1/CNRS Curated by ChEMBL | Assay Description Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assay | Eur J Med Chem 46: 1935-41 (2011) Article DOI: 10.1016/j.ejmech.2011.02.037 BindingDB Entry DOI: 10.7270/Q23R0T6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50343997 (2,4-dimethylpyrimido[2,1-a]isoquinolin-5-ium-3-ola...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
University Joseph Fourier-Grenoble 1/CNRS Curated by ChEMBL | Assay Description Inhibition of wild type CFTR expressed in CHO cells by [125I]iodide efflux assay | Eur J Med Chem 46: 1935-41 (2011) Article DOI: 10.1016/j.ejmech.2011.02.037 BindingDB Entry DOI: 10.7270/Q23R0T6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221949 (US9303035, 1.17) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 18.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50353346 (CHEMBL1831070) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human wild-type CFTR expressed in FRT cells assessed as inhibition of forskolin-induced short-circuit current by voltage clamp electrop... | J Med Chem 54: 5468-77 (2011) Article DOI: 10.1021/jm200505e BindingDB Entry DOI: 10.7270/Q2280809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50353349 (CHEMBL1831073) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human wild-type CFTR expressed in FRT cells assessed as inhibition of forskolin-induced short-circuit current by voltage clamp electrop... | J Med Chem 54: 5468-77 (2011) Article DOI: 10.1021/jm200505e BindingDB Entry DOI: 10.7270/Q2280809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50353345 (CHEMBL1831069) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human wild-type CFTR expressed in FRT cells assessed as inhibition of forskolin-induced short-circuit current by voltage clamp electrop... | J Med Chem 54: 5468-77 (2011) Article DOI: 10.1021/jm200505e BindingDB Entry DOI: 10.7270/Q2280809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221955 (US9303035, 1.23) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 29.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221979 (US9303035, 4.2) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221935 (US9303035, 1.3) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM300426 (US10130622, Example 00005) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie S.á.r.l.; Galapagos NV US Patent | Assay Description For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft... | US Patent US10130622 (2018) BindingDB Entry DOI: 10.7270/Q2KD20ZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50353351 (CHEMBL1831075) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human wild-type CFTR expressed in FRT cells coexpressing YFP-H148Q assessed as inhibition of cAMP agonist-induced iodide influx after 4... | J Med Chem 54: 5468-77 (2011) Article DOI: 10.1021/jm200505e BindingDB Entry DOI: 10.7270/Q2280809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50353338 (CHEMBL1831058) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human wild-type CFTR expressed in FRT cells assessed as inhibition of forskolin-induced short-circuit current by voltage clamp electrop... | J Med Chem 54: 5468-77 (2011) Article DOI: 10.1021/jm200505e BindingDB Entry DOI: 10.7270/Q2280809 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50353349 (CHEMBL1831073) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of human wild-type CFTR expressed in FRT cells coexpressing YFP-H148Q assessed as inhibition of cAMP agonist-induced iodide influx after 4... | J Med Chem 54: 5468-77 (2011) Article DOI: 10.1021/jm200505e BindingDB Entry DOI: 10.7270/Q2280809 | |||||||||||
More data for this Ligand-Target Pair |
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