Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'N-formyl peptide receptor 2/fMet-Leu-Phe receptor'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2/fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50490560 (CHEMBL2336646) Show SMILES CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H31N3O5S/c1-14(2)11-18(24-19(27)17(23-13-26)9-10-31-3)20(28)25-22(21(29)30)12-16(22)15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,23,26)(H,24,27)(H,25,28)(H,29,30)/t16-,17+,18+,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Agonist activity at FPR1/FPR2 receptor in human neutrophils assessed as induction of superoxide radical generation by spectrophotometric analysis				Bioorg Med Chem 21: 668-75 (2013) Article DOI: 10.1016/j.bmc.2012.11.046 BindingDB Entry DOI: 10.7270/Q2K64N1S
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2/fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50490561 (CHEMBL2336648) Show SMILES COC(=O)[C@@]1(C[C@H]1c1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC=O |r| Show InChI InChI=1S/C23H33N3O5S/c1-15(2)12-19(25-20(28)18(24-14-27)10-11-32-4)21(29)26-23(22(30)31-3)13-17(23)16-8-6-5-7-9-16/h5-9,14-15,17-19H,10-13H2,1-4H3,(H,24,27)(H,25,28)(H,26,29)/t17-,18-,19-,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Agonist activity at FPR1/FPR2 receptor in human neutrophils assessed as induction of chemotaxis after 60 mins				Bioorg Med Chem 21: 668-75 (2013) Article DOI: 10.1016/j.bmc.2012.11.046 BindingDB Entry DOI: 10.7270/Q2K64N1S
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2/fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50490562 (CHEBI:5158 | CHEMBL285518) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC=O |r| Show InChI InChI=1S/C22H33N3O5S/c1-15(2)12-18(24-20(27)17(23-14-26)10-11-31-4)21(28)25-19(22(29)30-3)13-16-8-6-5-7-9-16/h5-9,14-15,17-19H,10-13H2,1-4H3,(H,23,26)(H,24,27)(H,25,28)/t17-,18-,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Agonist activity at FPR1/FPR2 receptor in human neutrophils assessed as induction of chemotaxis after 60 mins				Bioorg Med Chem 21: 668-75 (2013) Article DOI: 10.1016/j.bmc.2012.11.046 BindingDB Entry DOI: 10.7270/Q2K64N1S
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2/fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50490560 (CHEMBL2336646) Show SMILES CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C22H31N3O5S/c1-14(2)11-18(24-19(27)17(23-13-26)9-10-31-3)20(28)25-22(21(29)30)12-16(22)15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,23,26)(H,24,27)(H,25,28)(H,29,30)/t16-,17+,18+,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.10	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Agonist activity at FPR1/FPR2 receptor in human neutrophils assessed as induction of chemotaxis after 60 mins				Bioorg Med Chem 21: 668-75 (2013) Article DOI: 10.1016/j.bmc.2012.11.046 BindingDB Entry DOI: 10.7270/Q2K64N1S
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2/fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50490563 (CHEMBL2336649) Show SMILES COC(=O)[C@@]1(C[C@@H]1c1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC=O |r| Show InChI InChI=1S/C23H33N3O5S/c1-15(2)12-19(25-20(28)18(24-14-27)10-11-32-4)21(29)26-23(22(30)31-3)13-17(23)16-8-6-5-7-9-16/h5-9,14-15,17-19H,10-13H2,1-4H3,(H,24,27)(H,25,28)(H,26,29)/t17-,18+,19+,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Agonist activity at FPR1/FPR2 receptor in human neutrophils assessed as induction of chemotaxis after 60 mins				Bioorg Med Chem 21: 668-75 (2013) Article DOI: 10.1016/j.bmc.2012.11.046 BindingDB Entry DOI: 10.7270/Q2K64N1S
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2/fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50490564 (CHEMBL2336647) Show SMILES COC(=O)[C@]1(C[C@H]1c1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC=O |r| Show InChI InChI=1S/C23H33N3O5S/c1-15(2)12-19(25-20(28)18(24-14-27)10-11-32-4)21(29)26-23(22(30)31-3)13-17(23)16-8-6-5-7-9-16/h5-9,14-15,17-19H,10-13H2,1-4H3,(H,24,27)(H,25,28)(H,26,29)/t17-,18-,19-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.70	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Agonist activity at FPR1/FPR2 receptor in human neutrophils assessed as induction of chemotaxis after 60 mins				Bioorg Med Chem 21: 668-75 (2013) Article DOI: 10.1016/j.bmc.2012.11.046 BindingDB Entry DOI: 10.7270/Q2K64N1S
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2/fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50490562 (CHEBI:5158 | CHEMBL285518) Show SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC=O |r| Show InChI InChI=1S/C22H33N3O5S/c1-15(2)12-18(24-20(27)17(23-14-26)10-11-31-4)21(28)25-19(22(29)30-3)13-16-8-6-5-7-9-16/h5-9,14-15,17-19H,10-13H2,1-4H3,(H,23,26)(H,24,27)(H,25,28)/t17-,18-,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Saga University Curated by ChEMBL					Assay Description Agonist activity at FPR1/FPR2 receptor in human neutrophils assessed as induction of superoxide radical generation by spectrophotometric analysis				Bioorg Med Chem 21: 668-75 (2013) Article DOI: 10.1016/j.bmc.2012.11.046 BindingDB Entry DOI: 10.7270/Q2K64N1S
					More data for this Ligand-Target Pair