Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280366 (2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280366 (2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280366 (2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280366 (2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280369 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280369 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280370 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280369 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280370 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280370 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280370 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280369 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280365 (4-{[2-(5-chloro-2-fluorophenyl)-5-cyclopropylpyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280365 (4-{[2-(5-chloro-2-fluorophenyl)-5-cyclopropylpyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280365 (4-{[2-(5-chloro-2-fluorophenyl)-5-cyclopropylpyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280365 (4-{[2-(5-chloro-2-fluorophenyl)-5-cyclopropylpyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280340 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280340 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280340 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280340 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280363 (2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{1H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 10.5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280363 (2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{1H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280363 (2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{1H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280363 (2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{1H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280352 (N-(2-aminoethyl)-4-[[2-(5-chloro-2-fluoro-phenyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM514529 (N-(2-aminoethyl)-4-[[2-(5-chloro-2-fluoro-phenyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280352 (N-(2-aminoethyl)-4-[[2-(5-chloro-2-fluoro-phenyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280352 (N-(2-aminoethyl)-4-[[2-(5-chloro-2-fluoro-phenyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280360 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280360 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280360 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280360 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280348 (N-(2-amino-2-oxo-ethyl)-4-[[2-(5-chloro-2-fluoro-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 11.7 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280348 (N-(2-amino-2-oxo-ethyl)-4-[[2-(5-chloro-2-fluoro-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280348 (N-(2-amino-2-oxo-ethyl)-4-[[2-(5-chloro-2-fluoro-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280348 (N-(2-amino-2-oxo-ethyl)-4-[[2-(5-chloro-2-fluoro-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280341 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280341 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM423157 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280341 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM50015639 (CHEMBL3260567 | USRE47141, Example 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Inhibition of ALK4 (unknown origin) by radioisotopic assay | J Med Chem 57: 4213-38 (2014) Article DOI: 10.1021/jm500115w BindingDB Entry DOI: 10.7270/Q2DV1MFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM50252542 (3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Inhibition of ALK4 (unknown origin) by radioisotopic assay | J Med Chem 57: 4213-38 (2014) Article DOI: 10.1021/jm500115w BindingDB Entry DOI: 10.7270/Q2DV1MFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280346 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-methoxy-4-pyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 23.5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280346 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-methoxy-4-pyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280346 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-methoxy-4-pyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280346 (4-[[2-(5-chloro-2-fluoro-phenyl)-5-methoxy-4-pyrid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280364 (2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{7H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280364 (2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{7H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280364 (2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{7H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23.7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280364 (2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{7H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 23.7 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair |
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