Compile Data Set for Download or QSAR

Found 874 hits Enz. Inhib. hit(s) with Target = 'Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308636 (BDBM308807 | US9656955, Example 150 | trans-N-[2-c...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C22H21ClF4N4O2S/c1-30-12-21(29-13-30)34(32,33)31-10-18(14-3-6-17(24)7-4-14)20(11-31)28-9-15-2-5-16(8-19(15)23)22(25,26)27/h2-8,12-13,18,20,28H,9-11H2,1H3/t18-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309163 (BDBM309164 | Trans-1-[(1-methyl-1H-imidazol-4-yl)s...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(OC(F)(F)F)c2)[C@@H](C1)C1CCCCO1 Show InChI InChI=1S/C20H25F3N4O4S/c1-26-12-19(24-13-26)32(28,29)27-10-16(18-7-2-3-8-30-18)17(11-27)25-14-5-4-6-15(9-14)31-20(21,22)23/h4-6,9,12-13,16-18,25H,2-3,7-8,10-11H2,1H3/t16-,17-,18?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309163 (BDBM309164 | Trans-1-[(1-methyl-1H-imidazol-4-yl)s...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(OC(F)(F)F)c2)[C@@H](C1)C1CCCCO1 Show InChI InChI=1S/C20H25F3N4O4S/c1-26-12-19(24-13-26)32(28,29)27-10-16(18-7-2-3-8-30-18)17(11-27)25-14-5-4-6-15(9-14)31-20(21,22)23/h4-6,9,12-13,16-18,25H,2-3,7-8,10-11H2,1H3/t16-,17-,18?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309199 (N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2ccccc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN6O2S/c1-30-14-24(28-16-30)34(32,33)31-12-20(17-7-9-19(25)10-8-17)22(13-31)29-23-11-21(26-15-27-23)18-5-3-2-4-6-18/h2-11,14-16,20,22H,12-13H2,1H3,(H,26,27,29)/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309202 (N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...) Show SMILES Cc1ccc(cc1)-c1cc(N[C@H]2CN(C[C@@H]2c2ccc(F)cc2)S(=O)(=O)c2cn(C)cn2)ncn1 Show InChI InChI=1S/C25H25FN6O2S/c1-17-3-5-19(6-4-17)22-11-24(28-15-27-22)30-23-13-32(35(33,34)25-14-31(2)16-29-25)12-21(23)18-7-9-20(26)10-8-18/h3-11,14-16,21,23H,12-13H2,1-2H3,(H,27,28,30)/t21-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309204 (6-(3-fluorophenyl)-N-{(3R,4S)-4-(4-fluorophenyl)-1...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2cccc(F)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H22F2N6O2S/c1-31-13-24(29-15-31)35(33,34)32-11-20(16-5-7-18(25)8-6-16)22(12-32)30-23-10-21(27-14-28-23)17-3-2-4-19(26)9-17/h2-10,13-15,20,22H,11-12H2,1H3,(H,27,28,30)/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309205 (6-(4-fluorophenyl)-N-{(3R,4S)-4-(4-fluorophenyl)-1...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2ccc(F)cc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H22F2N6O2S/c1-31-13-24(29-15-31)35(33,34)32-11-20(16-2-6-18(25)7-3-16)22(12-32)30-23-10-21(27-14-28-23)17-4-8-19(26)9-5-17/h2-10,13-15,20,22H,11-12H2,1H3,(H,27,28,30)/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309206 (6-(3-chlorophenyl)-N-{(3R,4S)-4-(4-fluorophenyl)-1...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2cccc(Cl)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H22ClFN6O2S/c1-31-13-24(29-15-31)35(33,34)32-11-20(16-5-7-19(26)8-6-16)22(12-32)30-23-10-21(27-14-28-23)17-3-2-4-18(25)9-17/h2-10,13-15,20,22H,11-12H2,1H3,(H,27,28,30)/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309207 (6-(4-chlorophenyl)-N-{(3R,4S)-4-(4-fluorophenyl)-1...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(ncn2)-c2ccc(Cl)cc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H22ClFN6O2S/c1-31-13-24(29-15-31)35(33,34)32-11-20(16-4-8-19(26)9-5-16)22(12-32)30-23-10-21(27-14-28-23)17-2-6-18(25)7-3-17/h2-10,13-15,20,22H,11-12H2,1H3,(H,27,28,30)/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309210 ((3R,4S)-N-(2,2-difluorohexyl)-4-(4-fluorophenyl)-1...) Show SMILES CCCCC(F)(F)CN[C@H]1CN(C[C@@H]1c1ccc(F)cc1)S(=O)(=O)c1cn(C)cn1 Show InChI InChI=1S/C20H27F3N4O2S/c1-3-4-9-20(22,23)13-24-18-11-27(30(28,29)19-12-26(2)14-25-19)10-17(18)15-5-7-16(21)8-6-15/h5-8,12,14,17-18,24H,3-4,9-11,13H2,1-2H3/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309221 ((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazo...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cccc(OCC(F)(F)F)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C22H22F4N4O3S/c1-29-12-21(27-14-29)34(31,32)30-10-19(15-5-7-16(23)8-6-15)20(11-30)28-17-3-2-4-18(9-17)33-13-22(24,25)26/h2-9,12,14,19-20,28H,10-11,13H2,1H3/t19-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309222 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(pyridin-...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(c2)-c2cccnc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C25H23F2N5O2S/c1-31-15-25(29-16-31)35(33,34)32-13-22(17-4-6-19(26)7-5-17)24(14-32)30-20-8-9-23(27)21(11-20)18-3-2-10-28-12-18/h2-12,15-16,22,24,30H,13-14H2,1H3/t22-,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309223 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(pyridin-...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(c2)-c2ccncc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C25H23F2N5O2S/c1-31-15-25(29-16-31)35(33,34)32-13-22(17-2-4-19(26)5-3-17)24(14-32)30-20-6-7-23(27)21(12-20)18-8-10-28-11-9-18/h2-12,15-16,22,24,30H,13-14H2,1H3/t22-,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309224 ((3R,4S)-N-(4-fluoro-3-methylphenyl)-4-(4-fluorophe...) Show SMILES Cc1cc(N[C@H]2CN(C[C@@H]2c2ccc(F)cc2)S(=O)(=O)c2cn(C)cn2)ccc1F Show InChI InChI=1S/C21H22F2N4O2S/c1-14-9-17(7-8-19(14)23)25-20-11-27(30(28,29)21-12-26(2)13-24-21)10-18(20)15-3-5-16(22)6-4-15/h3-9,12-13,18,20,25H,10-11H2,1-2H3/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309225 (5-fluoro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...) Show SMILES Cc1cc(N[C@H]2CN(C[C@@H]2c2ccc(F)cc2)S(=O)(=O)c2cn(C)cn2)ncc1F Show InChI InChI=1S/C20H21F2N5O2S/c1-13-7-19(23-8-17(13)22)25-18-10-27(30(28,29)20-11-26(2)12-24-20)9-16(18)14-3-5-15(21)6-4-14/h3-8,11-12,16,18H,9-10H2,1-2H3,(H,23,25)/t16-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309226 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(pyrimidi...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(c2)-c2cncnc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H22F2N6O2S/c1-31-13-24(29-15-31)35(33,34)32-11-21(16-2-4-18(25)5-3-16)23(12-32)30-19-6-7-22(26)20(8-19)17-9-27-14-28-10-17/h2-10,13-15,21,23,30H,11-12H2,1H3/t21-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309236 (4-chloro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(Cl)ccn2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H19ClFN5O2S/c1-25-11-19(23-12-25)29(27,28)26-9-16(13-2-4-15(21)5-3-13)17(10-26)24-18-8-14(20)6-7-22-18/h2-8,11-12,16-17H,9-10H2,1H3,(H,22,24)/t16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308582 (US9656955, Example 67 | trans-1-[(1-methyl-1H-imid...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(c2)C(F)(F)F)[C@@H](C1)c1ccccc1 Show InChI InChI=1S/C21H21F3N4O2S/c1-27-13-20(25-14-27)31(29,30)28-11-18(15-6-3-2-4-7-15)19(12-28)26-17-9-5-8-16(10-17)21(22,23)24/h2-10,13-14,18-19,26H,11-12H2,1H3/t18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309253 (4-(benzyloxy)-5-fluoro-N-{(3R,4S)-1-[(1-methyl-1H-...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCc3ccccc3)c(F)cn2)[C@H](C1)c1ccccc1 Show InChI InChI=1S/C26H26FN5O3S/c1-31-16-26(29-18-31)36(33,34)32-14-21(20-10-6-3-7-11-20)23(15-32)30-25-12-24(22(27)13-28-25)35-17-19-8-4-2-5-9-19/h2-13,16,18,21,23H,14-15,17H2,1H3,(H,28,30)/t21-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309272 (5-fluoro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(c(F)cn2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C20H18F5N5O2S/c1-29-10-19(27-11-29)33(31,32)30-8-14(12-2-4-13(21)5-3-12)17(9-30)28-18-6-15(20(23,24)25)16(22)7-26-18/h2-7,10-11,14,17H,8-9H2,1H3,(H,26,28)/t14-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309277 (Trans-4-(3-fluoropyridin-2-yl)-1-[(1-methyl-1H-imi...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(OCC(F)(F)F)c2)[C@@H](C1)c1ncccc1F Show InChI InChI=1S/C21H21F4N5O3S/c1-29-11-19(27-13-29)34(31,32)30-9-16(20-17(22)6-3-7-26-20)18(10-30)28-14-4-2-5-15(8-14)33-12-21(23,24)25/h2-8,11,13,16,18,28H,9-10,12H2,1H3/t16-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309278 ((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazo...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cccc(c2)-c2ccccn2)[C@H](C1)c1ccccc1 Show InChI InChI=1S/C25H25N5O2S/c1-29-17-25(27-18-29)33(31,32)30-15-22(19-8-3-2-4-9-19)24(16-30)28-21-11-7-10-20(14-21)23-12-5-6-13-26-23/h2-14,17-18,22,24,28H,15-16H2,1H3/t22-,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309280 (5-fluoro-N-{(3R,4S)-1-[(1-methyl-1H-imidazol-4-yl)...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)c(F)cn2)[C@H](C1)c1ccccc1 Show InChI InChI=1S/C21H21F4N5O3S/c1-29-11-20(27-13-29)34(31,32)30-9-15(14-5-3-2-4-6-14)17(10-30)28-19-7-18(16(22)8-26-19)33-12-21(23,24)25/h2-8,11,13,15,17H,9-10,12H2,1H3,(H,26,28)/t15-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309282 (5-chloro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)c(Cl)cn2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H20ClF4N5O3S/c1-30-10-20(28-12-30)35(32,33)31-8-15(13-2-4-14(23)5-3-13)17(9-31)29-19-6-18(16(22)7-27-19)34-11-21(24,25)26/h2-7,10,12,15,17H,8-9,11H2,1H3,(H,27,29)/t15-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309283 (N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)ccn2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H21F4N5O3S/c1-29-11-20(27-13-29)34(31,32)30-9-17(14-2-4-15(22)5-3-14)18(10-30)28-19-8-16(6-7-26-19)33-12-21(23,24)25/h2-8,11,13,17-18H,9-10,12H2,1H3,(H,26,28)/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309284 (5-chloro-N-{(3R,4S)-1-[(1-methyl-1H-imidazol-4-yl)...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)c(Cl)cn2)[C@H](C1)c1ccccc1 Show InChI InChI=1S/C21H21ClF3N5O3S/c1-29-11-20(27-13-29)34(31,32)30-9-15(14-5-3-2-4-6-14)17(10-30)28-19-7-18(16(22)8-26-19)33-12-21(23,24)25/h2-8,11,13,15,17H,9-10,12H2,1H3,(H,26,28)/t15-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309285 (N-{((3R,4S)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](C(ONc2ccccn2)C(F)(F)F)[C@H](C1)c1ccccc1 Show InChI InChI=1S/C21H22F3N5O3S/c1-28-13-19(26-14-28)33(30,31)29-11-16(15-7-3-2-4-8-15)17(12-29)20(21(22,23)24)32-27-18-9-5-6-10-25-18/h2-10,13-14,16-17,20H,11-12H2,1H3,(H,25,27)/t16-,17+,20?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309286 (5-fluoro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cc(OCC(F)(F)F)c(F)cn2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H20F5N5O3S/c1-30-10-20(28-12-30)35(32,33)31-8-15(13-2-4-14(22)5-3-13)17(9-31)29-19-6-18(16(23)7-27-19)34-11-21(24,25)26/h2-7,10,12,15,17H,8-9,11H2,1H3,(H,27,29)/t15-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309291 (Trans-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-4-(t...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(OCC(F)(F)F)c2)[C@@H](C1)C1CCCCO1 Show InChI InChI=1S/C21H27F3N4O4S/c1-27-12-20(25-14-27)33(29,30)28-10-17(19-7-2-3-8-31-19)18(11-28)26-15-5-4-6-16(9-15)32-13-21(22,23)24/h4-6,9,12,14,17-19,26H,2-3,7-8,10-11,13H2,1H3/t17-,18-,19?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309293 (Trans-N-[2-chloro-4-(trifluoromethyl)benzyl]-4-(3-...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@@H](NCc2ccc(cc2Cl)C(F)(F)F)[C@@H](C1)c1ncccc1F Show InChI InChI=1S/C20H19ClF4N6O2S/c1-30-11-18(28-29-30)34(32,33)31-9-14(19-16(22)3-2-6-26-19)17(10-31)27-8-12-4-5-13(7-15(12)21)20(23,24)25/h2-7,11,14,17,27H,8-10H2,1H3/t14-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308599 (US9656955, Example 85 | trans-4-(4-fluorophenyl)-1...) Show SMILES Cc1cccc(N[C@@H]2CN(C[C@H]2c2ccc(F)cc2)S(=O)(=O)c2cn(C)cn2)c1 Show InChI InChI=1S/C21H23FN4O2S/c1-15-4-3-5-18(10-15)24-20-12-26(29(27,28)21-13-25(2)14-23-21)11-19(20)16-6-8-17(22)9-7-16/h3-10,13-14,19-20,24H,11-12H2,1-2H3/t19-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308602 (BDBM308812 | US9656955, Example 88 | trans-4-(4-fl...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(c2)C(F)(F)F)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H20F4N4O2S/c1-28-12-20(26-13-28)32(30,31)29-10-18(14-5-7-16(22)8-6-14)19(11-29)27-17-4-2-3-15(9-17)21(23,24)25/h2-9,12-13,18-19,27H,10-11H2,1H3/t18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308608 (BDBM308811 | US9656955, Example 94 | trans-N-(3-ch...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(Cl)c2)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C20H20ClFN4O2S/c1-25-12-20(23-13-25)29(27,28)26-10-18(14-5-7-16(22)8-6-14)19(11-26)24-17-4-2-3-15(21)9-17/h2-9,12-13,18-19,24H,10-11H2,1H3/t18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309311 (US9656955, Example 836 | trans-4-(4-fluorophenyl)-...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@@H](Nc2cccc(OCC(F)(F)F)c2)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H21F4N5O3S/c1-29-12-20(27-28-29)34(31,32)30-10-18(14-5-7-15(22)8-6-14)19(11-30)26-16-3-2-4-17(9-16)33-13-21(23,24)25/h2-9,12,18-19,26H,10-11,13H2,1H3/t18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309312 ((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-1,2,3-t...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2cccc(OC(F)(F)F)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C20H19F4N5O3S/c1-28-12-19(26-27-28)33(30,31)29-10-17(13-5-7-14(21)8-6-13)18(11-29)25-15-3-2-4-16(9-15)32-20(22,23)24/h2-9,12,17-18,25H,10-11H2,1H3/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309313 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(OC(F)(F)F)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C20H18F5N5O3S/c1-29-11-19(27-28-29)34(31,32)30-9-15(12-2-4-13(21)5-3-12)17(10-30)26-14-6-7-16(22)18(8-14)33-20(23,24)25/h2-8,11,15,17,26H,9-10H2,1H3/t15-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309314 ((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-1,2,3-t...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2cccc(c2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C20H19F4N5O2S/c1-28-12-19(26-27-28)32(30,31)29-10-17(13-5-7-15(21)8-6-13)18(11-29)25-16-4-2-3-14(9-16)20(22,23)24/h2-9,12,17-18,25H,10-11H2,1H3/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309315 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(c2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C20H18F5N5O2S/c1-29-11-19(27-28-29)33(31,32)30-9-15(12-2-4-13(21)5-3-12)18(10-30)26-14-6-7-17(22)16(8-14)20(23,24)25/h2-8,11,15,18,26H,9-10H2,1H3/t15-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309316 ((3R,4S)-N-(3-chlorophenyl)-4-(4-fluorophenyl)-1-[(...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2cccc(Cl)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H19ClFN5O2S/c1-25-12-19(23-24-25)29(27,28)26-10-17(13-5-7-15(21)8-6-13)18(11-26)22-16-4-2-3-14(20)9-16/h2-9,12,17-18,22H,10-11H2,1H3/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309317 ((3R,4S)-N-(3-chloro-4-fluorophenyl)-4-(4-fluorophe...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(Cl)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C19H18ClF2N5O2S/c1-26-11-19(24-25-26)30(28,29)27-9-15(12-2-4-13(21)5-3-12)18(10-27)23-14-6-7-17(22)16(20)8-14/h2-8,11,15,18,23H,9-10H2,1H3/t15-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308645 (US9656955, Example 159 | trans-4-(4-fluorophenyl)-...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2ccc(F)c(c2)C(F)(F)F)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H19F5N4O2S/c1-29-11-20(27-12-29)33(31,32)30-9-16(13-2-4-14(22)5-3-13)19(10-30)28-15-6-7-18(23)17(8-15)21(24,25)26/h2-8,11-12,16,19,28H,9-10H2,1H3/t16-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308646 (BDBM308873 | US9656955, Example 160 | trans-N-(3-c...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2ccc(F)c(Cl)c2)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C20H19ClF2N4O2S/c1-26-11-20(24-12-26)30(28,29)27-9-16(13-2-4-14(22)5-3-13)19(10-27)25-15-6-7-18(23)17(21)8-15/h2-8,11-12,16,19,25H,9-10H2,1H3/t16-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308662 (BDBM308809 | US9656955, Example 176 | trans-4-(4-f...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(OC(F)(F)F)c2)[C@@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H20F4N4O3S/c1-28-12-20(26-13-28)33(30,31)29-10-18(14-5-7-15(22)8-6-14)19(11-29)27-16-3-2-4-17(9-16)32-21(23,24)25/h2-9,12-13,18-19,27H,10-11H2,1H3/t18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308706 (US9656955, Example 220 | trans-1-[(1-methyl-1H-imi...) Show SMILES CC(C)c1cccc(N[C@@H]2CN(C[C@H]2c2ccccc2)S(=O)(=O)c2cn(C)cn2)c1 Show InChI InChI=1S/C23H28N4O2S/c1-17(2)19-10-7-11-20(12-19)25-22-14-27(13-21(22)18-8-5-4-6-9-18)30(28,29)23-15-26(3)16-24-23/h4-12,15-17,21-22,25H,13-14H2,1-3H3/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308712 (US9656955, Example 226 | trans-1-[(1-methyl-1H-imi...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cccc(OC(F)(F)F)c2)[C@@H](C1)c1ccccc1 Show InChI InChI=1S/C21H21F3N4O3S/c1-27-13-20(25-14-27)32(29,30)28-11-18(15-6-3-2-4-7-15)19(12-28)26-16-8-5-9-17(10-16)31-21(22,23)24/h2-10,13-14,18-19,26H,11-12H2,1H3/t18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308815 ((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazo...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2cccc(OC(F)(F)F)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C21H20F4N4O3S/c1-28-12-20(26-13-28)33(30,31)29-10-18(14-5-7-15(22)8-6-14)19(11-29)27-16-3-2-4-17(9-16)32-21(23,24)25/h2-9,12-13,18-19,27H,10-11H2,1H3/t18-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM294256 (Cis-N-(1-(4-benzyl-3-(methylamino)chroman-6-yl)aze...) Show SMILES CNC1COc2ccc(cc2C1Cc1ccccc1)N1CC(C1)NS(=O)(=O)CC1CC1 Show InChI InChI=1S/C24H31N3O3S/c1-25-23-15-30-24-10-9-20(12-22(24)21(23)11-17-5-3-2-4-6-17)27-13-19(14-27)26-31(28,29)16-18-7-8-18/h2-6,9-10,12,18-19,21,23,25-26H,7-8,11,13-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description 1. [3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,0...				US Patent US9586945 (2017) BindingDB Entry DOI: 10.7270/Q2W66NTN
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM294276 (Cis-N-(1-(4-benzyl-7-fluoro-3-(methylamino)chroman...) Show SMILES CCCS(=O)(=O)NC1CN(C1)c1cc2C(Cc3ccccc3)C(COc2cc1F)NC Show InChI InChI=1S/C23H30FN3O3S/c1-3-9-31(28,29)26-17-13-27(14-17)22-11-19-18(10-16-7-5-4-6-8-16)21(25-2)15-30-23(19)12-20(22)24/h4-8,11-12,17-18,21,25-26H,3,9-10,13-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description 1. [3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,0...				US Patent US9586945 (2017) BindingDB Entry DOI: 10.7270/Q2W66NTN
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM294227 (US9586942, 1) Show SMILES Cn1cnc(c1)S(=O)(=O)NC1CN(C1)c1ccc2CC[C@@H]([C@H](Cc3ccccc3)c2c1)N1CCC1 Show InChI InChI=1S/C27H33N5O2S/c1-30-18-27(28-19-30)35(33,34)29-22-16-32(17-22)23-10-8-21-9-11-26(31-12-5-13-31)25(24(21)15-23)14-20-6-3-2-4-7-20/h2-4,6-8,10,15,18-19,22,25-26,29H,5,9,11-14,16-17H2,1H3/t25-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,000 cells per well in 96 well Cytostar-T scintillation microplates (Amersha...				US Patent US9586942 (2017) BindingDB Entry DOI: 10.7270/Q20Z75BG
					More data for this Ligand-Target Pair
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM294228 (N-(1-((7S,8R)-7-(azetidin-1-yl)-8-benzyl-5,6,7,8-t...) Show SMILES Cn1cnc(c1)S(=O)(=O)NC1CN(C1)c1ccc2CC[C@@H]([C@H](Cc3ccccc3)c2c1)N1CCC1 |r| Show InChI InChI=1S/C27H33N5O2S/c1-30-18-27(28-19-30)35(33,34)29-22-16-32(17-22)23-10-8-21-9-11-26(31-12-5-13-31)25(24(21)15-23)14-20-6-3-2-4-7-20/h2-4,6-8,10,15,18-19,22,25-26,29H,5,9,11-14,16-17H2,1H3/t25-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,000 cells per well in 96 well Cytostar-T scintillation microplates (Amersha...				US Patent US9586942 (2017) BindingDB Entry DOI: 10.7270/Q20Z75BG
					More data for this Ligand-Target Pair

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