Found 99 hits Enz. Inhib. hit(s) with Target = 'Nucleosome-remodeling factor subunit BPTF' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50443230
(CHEMBL3086885)Show SMILES Cc1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(N)c(Cl)c1O |w:4.3| Show InChI InChI=1S/C18H16ClN5O3S/c1-11-10-14(17(20)16(19)18(11)25)23-22-12-5-7-13(8-6-12)28(26,27)24-15-4-2-3-9-21-15/h2-10,25H,20H2,1H3,(H,21,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| Assay Description Displacement of fluorescein-labeled MS239 from recombinant human BPTF after 1 hr by fluorescence anisotropy assay |
J Med Chem 56: 9251-64 (2013)
Article DOI: 10.1021/jm401334s BindingDB Entry DOI: 10.7270/Q2ZW1NCF |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50443232
(CHEMBL3086883)Show SMILES Cc1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(N)cc1O |w:4.3| Show InChI InChI=1S/C18H17N5O3S/c1-12-10-16(15(19)11-17(12)24)22-21-13-5-7-14(8-6-13)27(25,26)23-18-4-2-3-9-20-18/h2-11,24H,19H2,1H3,(H,20,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 6.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| Assay Description Displacement of fluorescein-labeled MS239 from recombinant human BPTF after 1 hr by fluorescence anisotropy assay |
J Med Chem 56: 9251-64 (2013)
Article DOI: 10.1021/jm401334s BindingDB Entry DOI: 10.7270/Q2ZW1NCF |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573840
(CHEMBL4860578)Show SMILES CCCNc1cc(nc(n1)S(C)(=O)=O)-c1ccc2n(CCCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50571296
(CHEMBL4873093)Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(NC2=C(C)C(=O)N3C=C(C=CC3N2)c2cnn(c2)C2CC2)c(F)c1 |c:16,22,24| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BPTF in human HEK293 cells by NanoBRET assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128208 BindingDB Entry DOI: 10.7270/Q2M0497K |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573844
(CHEMBL4873042)Show SMILES CN(C)CCCn1ccc2cc(ccc12)-c1nc(nc2[nH]ccc12)S(C)(=O)=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573839
(CHEMBL4870170)Show SMILES CCNc1cc(nc(n1)S(C)(=O)=O)-c1ccc2n(CCCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50571296
(CHEMBL4873093)Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(NC2=C(C)C(=O)N3C=C(C=CC3N2)c2cnn(c2)C2CC2)c(F)c1 |c:16,22,24| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BPTF (unknown origin) by AlphaScreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128208 BindingDB Entry DOI: 10.7270/Q2M0497K |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573837
(CHEMBL4867072)Show SMILES CNc1cc(nc(n1)S(C)(=O)=O)-c1ccc2n(CCCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573200
(CHEMBL4861491) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573838
(CHEMBL4868713)Show SMILES CNc1cc(nc(n1)S(C)(=O)=O)-c1ccc2n(CCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573201
(CHEMBL4848701) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573849
(CHEMBL4866637)Show SMILES CCCNc1cc(nc(n1)S(C)(=O)=O)-c1ccc2n(CCCN(C)C)cc(C)c2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573845
(CHEMBL4851594)Show SMILES CNc1cc(nc(n1)[S+](C)[O-])-c1ccc2n(CCCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573848
(CHEMBL4862619)Show SMILES CCCNc1cc(nc(n1)S(C)(=O)=O)-c1cc(OC)c2n(CCCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573197
(CHEMBL4872300) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573841
(CHEMBL4852588)Show SMILES CCCCNc1cc(nc(n1)S(C)(=O)=O)-c1ccc2n(CCCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573846
(CHEMBL4853486)Show SMILES CCCNc1cc(nc(n1)[S+](C)[O-])-c1ccc2n(CCCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573850
(CHEMBL4861221)Show SMILES CN(C)CCCn1cc(C)c2cc(ccc12)-c1nc(nc2[nH]ccc12)S(C)(=O)=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 157 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573198
(CHEMBL4848138) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50234940
(CHEMBL4101756)Show InChI InChI=1S/C12H13ClN4O/c1-17-12(18)11(13)10(7-15-17)16-9-5-3-2-4-8(9)6-14/h2-5,7,16H,6,14H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573192
(CHEMBL4850516) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573842
(CHEMBL4863921)Show SMILES CCC(C)Nc1cc(nc(n1)S(C)(=O)=O)-c1ccc2n(CCCN(C)C)ccc2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 288 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573190
(CHEMBL4866748) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573191
(CHEMBL4870218) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50514899
(CHEMBL4461619)Show SMILES CN(C)CCCOc1ccc(cc1)-c1cc(NCCCn2cccn2)nc(n1)S(C)(=O)=O Show InChI InChI=1S/C22H30N6O3S/c1-27(2)13-6-16-31-19-9-7-18(8-10-19)20-17-21(26-22(25-20)32(3,29)30)23-11-4-14-28-15-5-12-24-28/h5,7-10,12,15,17H,4,6,11,13-14,16H2,1-3H3,(H,23,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BPTF (unknown origin) by AlphaScreen assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128208 BindingDB Entry DOI: 10.7270/Q2M0497K |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573193
(CHEMBL4848082) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573203
(CHEMBL4863631) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573202
(CHEMBL4877696) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573836
(CHEMBL4861375) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 698 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573188
(CHEMBL4850913) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573204
(CHEMBL4863529) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573195
(CHEMBL4855881) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50234924
(CHEMBL4065579)Show InChI InChI=1S/C11H10ClN3O/c1-15-11(16)10(12)9(7-13-15)14-8-5-3-2-4-6-8/h2-7,14H,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573196
(CHEMBL4877118) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50157606
(CHEMBL3785432)Show SMILES CCCS(=O)(=O)c1nc(NC2CC2)cc(n1)-c1ccc2n(ccc2c1)C1CC(C)(C)NC(C)(C)C1 Show InChI InChI=1S/C27H37N5O2S/c1-6-13-35(33,34)25-29-22(15-24(30-25)28-20-8-9-20)18-7-10-23-19(14-18)11-12-32(23)21-16-26(2,3)31-27(4,5)17-21/h7,10-12,14-15,20-21,31H,6,8-9,13,16-17H2,1-5H3,(H,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Alphascreen assay. Binding to FALZA (domain start/stop: S2791-H2911) by alphascreen assay |
Medchemcomm 7: 2246-2264 (2016)
Article DOI: 10.1039/c6md00373g BindingDB Entry DOI: 10.7270/Q2CZ3BRT |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50234923
(CHEMBL4069412)Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r| Show InChI InChI=1S/C17H21BrN4O/c1-21-10-13(12-6-4-3-5-7-12)8-14(11-21)20-15-9-19-22(2)17(23)16(15)18/h3-7,9,13-14,20H,8,10-11H2,1-2H3/t13-,14+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573835
(CHEMBL4872350) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573847
(CHEMBL4872974)Show SMILES CNc1cc(nc(n1)S(C)(=O)=O)-c1ccc2ccn(CCCN(C)C)c2c1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573187
(CHEMBL4861822) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573194
(CHEMBL4858548) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573186
(CHEMBL4872107) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573834
(CHEMBL4863800) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573185
(CHEMBL4853420) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573183
(CHEMBL4867912) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573199
(CHEMBL4849136) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573189
(CHEMBL4857332) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50571298
(CHEMBL4846726) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human recombinant BPTF expressed in Escherichia coli BL21-Codonplus (DE3)-RIPL incubated for 30 mins by HTRF assa... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128208 BindingDB Entry DOI: 10.7270/Q2M0497K |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50573843
(CHEMBL4875586)Show SMILES CN(C)CCCn1ccc2cc(ccc12)-c1cc(nc(n1)S(C)(=O)=O)N(C)C | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00721 BindingDB Entry DOI: 10.7270/Q2M61Q27 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50558065
(CHEMBL4780530)Show SMILES C[C@@H]1CN(c2ccc(Cl)cc2)c2cc(ccc2-n2c(C)nnc12)-c1ccc(N)nc1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BPTF (unknown origin) measured after 70 mins by TR-FRET assay |
Citation and Details
Article DOI: 10.1021/ml500411h BindingDB Entry DOI: 10.7270/Q2DV1PK7 |
More data for this Ligand-Target Pair | |
Nucleosome-remodeling factor subunit BPTF
(Homo sapiens (Human)) | BDBM50234944
(CHEMBL4072538 | US10239861, Example 60)Show InChI InChI=1S/C11H17ClN4O/c1-15-5-3-4-8(7-15)14-9-6-13-16(2)11(17)10(9)12/h6,8,14H,3-5,7H2,1-2H3/t8-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |