Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Breast cancer type 2 susceptibility protein'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Breast cancer type 2 susceptibility protein/DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM65520 (N-cyclopentyl-2-((5-((2-oxobenzo[d]thiazol-3(2H)-y...) Show SMILES O=C(CSc1nnc(Cn2c3ccccc3sc2=O)n1CCCc1ccccc1)NC1CCCC1 Show InChI InChI=1S/C26H29N5O2S2/c32-24(27-20-12-4-5-13-20)18-34-25-29-28-23(30(25)16-8-11-19-9-2-1-3-10-19)17-31-21-14-6-7-15-22(21)35-26(31)33/h1-3,6-7,9-10,14-15,20H,4-5,8,11-13,16-18H2,(H,27,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia					Assay Description This assay is an efficient tool for directly measuring inhibition of the BRC4−Rad51 interaction, at a molecular level, which is described by Ra...				ACS Chem Biol 12: 2491-2497 (2017) Article DOI: 10.1021/acschembio.7b00707 BindingDB Entry DOI: 10.7270/Q2WS8RD4
					More data for this Ligand-Target Pair
Breast cancer type 2 susceptibility protein/DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM65519 (F0665-0303 | N-cyclopentyl-2-((5-((2-oxobenzo[d]th...) Show SMILES O=C(CSc1nnc(Cn2c3ccccc3sc2=O)n1CCc1ccccc1)NC1CCCC1 Show InChI InChI=1S/C25H27N5O2S2/c31-23(26-19-10-4-5-11-19)17-33-24-28-27-22(29(24)15-14-18-8-2-1-3-9-18)16-30-20-12-6-7-13-21(20)34-25(30)32/h1-3,6-9,12-13,19H,4-5,10-11,14-17H2,(H,26,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia					Assay Description This assay is an efficient tool for directly measuring inhibition of the BRC4−Rad51 interaction, at a molecular level, which is described by Ra...				ACS Chem Biol 12: 2491-2497 (2017) Article DOI: 10.1021/acschembio.7b00707 BindingDB Entry DOI: 10.7270/Q2WS8RD4
					More data for this Ligand-Target Pair