Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Caspase-10 (Homo sapiens (Human)) | BDBM50160974 (CHEMBL366927 | [3-(2-{5-tert-Butyl-3-[(4-methyl-fu...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory concentration against caspase-10 in neuronal precursor (NT2) cells | Bioorg Med Chem Lett 15: 1173-80 (2005) Article DOI: 10.1016/j.bmcl.2004.12.006 BindingDB Entry DOI: 10.7270/Q2D50MGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM50160957 (CHEMBL179503 | [3-(2-{5-tert-Butyl-3-[(4-methyl-fu...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory concentration against casp-10 in neuronal precursor (NT2) cells | Bioorg Med Chem Lett 15: 1173-80 (2005) Article DOI: 10.1016/j.bmcl.2004.12.006 BindingDB Entry DOI: 10.7270/Q2D50MGS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM50426562 (CHEMBL2324339) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Inhibition of caspase-10 (unknown origin) | ACS Med Chem Lett 4: 163-4 (2013) Article DOI: 10.1021/ml400021b BindingDB Entry DOI: 10.7270/Q2736S86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM50426563 (CHEMBL2323967) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Inhibition of caspase-10 (unknown origin) | ACS Med Chem Lett 4: 163-4 (2013) Article DOI: 10.1021/ml400021b BindingDB Entry DOI: 10.7270/Q2736S86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM50426566 (CHEMBL2324341) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Inhibition of caspase-10 (unknown origin) | ACS Med Chem Lett 4: 163-4 (2013) Article DOI: 10.1021/ml400021b BindingDB Entry DOI: 10.7270/Q2736S86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM160849 (US9045524, 123) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVAGENESIS FOUNDATION US Patent | Assay Description The inhibition of the activity of Caspase-1 to -10 by four different compounds (#53, #111, #123 & Z-DEVD-FMK used as a prodrug: z-D(OMe)E(OMe)VD(OMe)... | US Patent US9045524 (2015) BindingDB Entry DOI: 10.7270/Q2GT5KX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM50426564 (CHEMBL2323966) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Inhibition of caspase-10 (unknown origin) | ACS Med Chem Lett 4: 163-4 (2013) Article DOI: 10.1021/ml400021b BindingDB Entry DOI: 10.7270/Q2736S86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM50426565 (CHEMBL2324340) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Inhibition of caspase-10 (unknown origin) | ACS Med Chem Lett 4: 163-4 (2013) Article DOI: 10.1021/ml400021b BindingDB Entry DOI: 10.7270/Q2736S86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM160786 (US10167313, Compound 53 | US9045524, 53) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVAGENESIS FOUNDATION US Patent | Assay Description The inhibition of the activity of Caspase-1 to -10 by four different compounds (#53, #111, #123 & Z-DEVD-FMK used as a prodrug: z-D(OMe)E(OMe)VD(OMe)... | US Patent US9045524 (2015) BindingDB Entry DOI: 10.7270/Q2GT5KX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM160841 (US9045524, 111) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVAGENESIS FOUNDATION US Patent | Assay Description The inhibition of the activity of Caspase-1 to -10 by four different compounds (#53, #111, #123 & Z-DEVD-FMK used as a prodrug: z-D(OMe)E(OMe)VD(OMe)... | US Patent US9045524 (2015) BindingDB Entry DOI: 10.7270/Q2GT5KX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-10 (Homo sapiens (Human)) | BDBM50302107 (CHEMBL567893 | Grassystatin A) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Inhibition of caspase 10 after 10 to 15 mins by fluorescence assay | J Med Chem 52: 5732-47 (2009) Article DOI: 10.1021/jm9009394 BindingDB Entry DOI: 10.7270/Q2BG2PXP | |||||||||||
More data for this Ligand-Target Pair |