Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220398 (US9296708, 4, ARM-P4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0200 | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220397 (US9296708, 3, ARM-P2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0240 | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220396 (US9296708, 2, ARM-P1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0470 | n/a | 1.05 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220408 (US9296708, 14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0600 | n/a | 1.36 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220395 (US9296708, 1, ARM-P0) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0780 | n/a | 1.76 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220407 (US9296708, 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0780 | n/a | 1.78 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220399 (US9296708, 5, ARM-P6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.101 | n/a | 2.29 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220400 (US9296708, 6, ARM-P8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.145 | n/a | 3.29 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220409 (US9296708, 15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.730 | n/a | 16.6 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220410 (US9296708, 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.970 | n/a | 21.9 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220404 (US9296708, 10, MeO-P4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | US Patent | 1.34 | n/a | 30.2 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220402 (US9296708, 8, MeO-P0) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.35 | n/a | 30.5 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220401 (US9296708, 7, ARM-P12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.65 | n/a | 37.3 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220403 (US9296708, 9, MeO-P2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.81 | n/a | 40.8 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220405 (US9296708, 11, MeO-P8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.79 | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220406 (US9296708, 12, MeO-P12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.30 | n/a | 165 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220411 (US9296708, 17) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 15.1 | n/a | 342 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM321150 (US10174049, Example 17 | US9738658, Example 17 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline LLC US Patent | Assay Description For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p... | US Patent US9738658 (2017) BindingDB Entry DOI: 10.7270/Q26Q20BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM321150 (US10174049, Example 17 | US9738658, Example 17 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxosmithkline LLC US Patent | Assay Description For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p... | US Patent US10174049 (2019) BindingDB Entry DOI: 10.7270/Q2X92DCR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM411440 (US10385066, Example 17) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline LLC US Patent | Assay Description LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3... | US Patent US10385066 (2019) BindingDB Entry DOI: 10.7270/Q2WD42X8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM321150 (US10174049, Example 17 | US9738658, Example 17 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE LLC US Patent | Assay Description For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p... | US Patent US9796729 (2017) BindingDB Entry DOI: 10.7270/Q2057J2H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM411430 (US10385066, Example 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline LLC US Patent | Assay Description LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3... | US Patent US10385066 (2019) BindingDB Entry DOI: 10.7270/Q2WD42X8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Rattus norvegicus (rat)) | BDBM50385398 (CHEMBL2036730) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of rat DGAT1 | Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50385398 (CHEMBL2036730) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of DGAT1-mediated triacylglycerol synthesis in human HuTu80 cells | Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM351918 (4-Amino-6-(1-(3-(trifluoromethoxy)phenyl)-1H-indol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GLAXOSMITHKLINE LLC US Patent | Assay Description For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p... | US Patent US9796729 (2017) BindingDB Entry DOI: 10.7270/Q2057J2H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM336120 (US9738658, Example 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline LLC US Patent | Assay Description For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p... | US Patent US9738658 (2017) BindingDB Entry DOI: 10.7270/Q26Q20BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM321135 (US10174049, Example 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxosmithkline LLC US Patent | Assay Description For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p... | US Patent US10174049 (2019) BindingDB Entry DOI: 10.7270/Q2X92DCR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50385398 (CHEMBL2036730) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation... | Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220924 (US9302996, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220966 (US9302996, 114 | US9302996, 81) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50523583 (CHEMBL4585408) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Inc Curated by ChEMBL | Assay Description Inhibition of human DGAT1 | Bioorg Med Chem Lett 29: 1380-1385 (2019) Article DOI: 10.1016/j.bmcl.2019.03.039 BindingDB Entry DOI: 10.7270/Q2348PSJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220983 (US9302996, 98-3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220908 (US9302996, 23) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM395359 (US10308636, Example 44-6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were... | Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220962 (US9302996, 77) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220986 (US9302996, 101-3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220975 (US9302996, 90) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.870 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM395327 (US10308636, Example 4-15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were... | Bioorg Med Chem Lett 19: 3485-8 (2009) BindingDB Entry DOI: 10.7270/Q28S4S76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM220947 (US9302996, 62-3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.960 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse)) | BDBM50437388 (CHEMBL3037924) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of mouse DGAT1 | ACS Med Chem Lett 4: 773-8 (2013) Article DOI: 10.1021/ml400168h BindingDB Entry DOI: 10.7270/Q2NG4S28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM221020 (US9302996, 135) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.4 | 30 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w... | US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50287311 (CHEMBL4176968) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ... | ACS Med Chem Lett 9: 103-108 (2018) Article DOI: 10.1021/acsmedchemlett.7b00450 BindingDB Entry DOI: 10.7270/Q2V127C9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM209558 (US9271969, 46) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
KAINOS MEDICINE, INC. US Patent | Assay Description Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ... | US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM209552 (US9271969, 40) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
KAINOS MEDICINE, INC. US Patent | Assay Description Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ... | US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM209544 (US9271969, 32) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
KAINOS MEDICINE, INC. US Patent | Assay Description Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ... | US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse)) | BDBM209551 (US9271969, 39) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
KAINOS MEDICINE, INC. US Patent | Assay Description Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ... | US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse)) | BDBM209550 (US9271969, 38) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
KAINOS MEDICINE, INC. US Patent | Assay Description Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ... | US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse)) | BDBM209544 (US9271969, 32) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
KAINOS MEDICINE, INC. US Patent | Assay Description Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ... | US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse)) | BDBM209531 (US9271969, 19) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
KAINOS MEDICINE, INC. US Patent | Assay Description Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ... | US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse)) | BDBM209526 (US9271969, 14) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.4 | 25 |
KAINOS MEDICINE, INC. US Patent | Assay Description Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ... | US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8 | |||||||||||
More data for this Ligand-Target Pair |
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