Compile Data Set for Download or QSAR

Found 2328 hits Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138133 (US8871783, 19) Show SMILES O=C(N[C@@H](Cc1ccc(s1)-c1ccc2C(=O)OCc2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2 |r| Show InChI InChI=1S/C22H21N3O3S/c23-10-16(25-21(26)20-13-1-3-15(8-13)24-20)9-17-4-6-19(29-17)12-2-5-18-14(7-12)11-28-22(18)27/h2,4-7,13,15-16,20,24H,1,3,8-9,11H2,(H,25,26)/t13-,15+,16-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.900	-51.6	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138118 (US8871783, 4) Show SMILES CN1C(=O)C(=O)c2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C23H22N4O3S/c1-27-18-9-12(3-6-17(18)21(28)23(27)30)19-7-5-16(31-19)10-15(11-24)26-22(29)20-13-2-4-14(8-13)25-20/h3,5-7,9,13-15,20,25H,2,4,8,10H2,1H3,(H,26,29)/t13-,14+,15-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.10	-49.5	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138136 (US8871783, 22) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1cc(F)c(CC(NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C23H23FN4O2S/c1-28-18-7-13(3-2-12(18)8-21(28)29)19-10-17(24)20(31-19)9-16(11-25)27-23(30)22-14-4-5-15(6-14)26-22/h2-3,7,10,14-16,22,26H,4-6,8-9H2,1H3,(H,27,30)/t14-,15+,16?,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.20	-49.4	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138137 (US8871783, 23) Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(cc1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C25H31N5O3S2/c1-29-10-12-30(13-11-29)35(32,33)22-7-3-17(4-8-22)23-9-6-21(34-23)15-20(16-26)28-25(31)24-18-2-5-19(14-18)27-24/h3-4,6-9,18-20,24,27H,2,5,10-15H2,1H3,(H,28,31)/t18-,19+,20-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.90	-48.7	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138117 (US8871783, 3) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C23H24N4O2S/c1-27-19-9-14(3-2-13(19)10-21(27)28)20-7-6-18(30-20)11-17(12-24)26-23(29)22-15-4-5-16(8-15)25-22/h2-3,6-7,9,15-17,22,25H,4-5,8,10-11H2,1H3,(H,26,29)/t15-,16+,17-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.20	-48.5	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138135 (US8871783, 21) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1sc(CC(NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1Br |r| Show InChI InChI=1S/C23H22BrFN4O2S/c1-29-16-7-13(3-2-11(16)8-18(29)30)22-19(24)20(25)17(32-22)9-15(10-26)28-23(31)21-12-4-5-14(6-12)27-21/h2-3,7,12,14-15,21,27H,4-6,8-9H2,1H3,(H,28,31)/t12-,14+,15?,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.60	-48.2	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138139 (US8871783, 25) Show SMILES CC1(C)OC(=O)c2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C24H25N3O3S/c1-24(2)19-10-13(4-7-18(19)23(29)30-24)20-8-6-17(31-20)11-16(12-25)27-22(28)21-14-3-5-15(9-14)26-21/h4,6-8,10,14-16,21,26H,3,5,9,11H2,1-2H3,(H,27,28)/t14-,15+,16-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	-47.9	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138131 (US8871783, 17) Show SMILES O=C(N[C@@H](Cc1ccc(s1)-c1ccc2CC(=O)Nc2c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2 |r| Show InChI InChI=1S/C22H22N4O2S/c23-11-16(25-22(28)21-14-3-4-15(7-14)24-21)10-17-5-6-19(29-17)13-2-1-12-9-20(27)26-18(12)8-13/h1-2,5-6,8,14-16,21,24H,3-4,7,9-10H2,(H,25,28)(H,26,27)/t14-,15+,16-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.20	-47.8	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138128 (US8871783, 14) Show SMILES CC(=O)c1ccc(s1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C20H21N3O2S2/c1-11(24)16-6-7-18(27-16)17-5-4-15(26-17)9-14(10-21)23-20(25)19-12-2-3-13(8-12)22-19/h4-7,12-14,19,22H,2-3,8-9H2,1H3,(H,23,25)/t12-,13+,14-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	13.4	-44.9	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138115 (US8871783, 1) Show SMILES Fc1cc(ccc1C#N)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C21H19FN4OS/c22-18-8-12(1-2-14(18)10-23)19-6-5-17(28-19)9-16(11-24)26-21(27)20-13-3-4-15(7-13)25-20/h1-2,5-6,8,13,15-16,20,25H,3-4,7,9H2,(H,26,27)/t13-,15+,16-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13.7	-44.9	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138126 (US8871783, 12) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1cnc(CC(NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C22H23N5O2S/c1-27-17-7-13(3-2-12(17)8-20(27)28)18-11-24-19(30-18)9-16(10-23)26-22(29)21-14-4-5-15(6-14)25-21/h2-3,7,11,14-16,21,25H,4-6,8-9H2,1H3,(H,26,29)/t14-,15+,16?,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14.9	-44.7	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138140 (US8871783, 26) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C21H23N3O3S2/c1-29(26,27)18-4-2-3-13(10-18)19-8-7-17(28-19)11-16(12-22)24-21(25)20-14-5-6-15(9-14)23-20/h2-4,7-8,10,14-16,20,23H,5-6,9,11H2,1H3,(H,24,25)/t14-,15+,16-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16.7	-44.4	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138130 (US8871783, 16) Show SMILES CCn1cc(cn1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C19H23N5OS/c1-2-24-11-13(10-21-24)17-6-5-16(26-17)8-15(9-20)23-19(25)18-12-3-4-14(7-12)22-18/h5-6,10-12,14-15,18,22H,2-4,7-8H2,1H3,(H,23,25)/t12-,14+,15-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17.1	-44.3	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138116 (US8871783, 2) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C21H23N3O3S2/c1-29(26,27)18-7-3-13(4-8-18)19-9-6-17(28-19)11-16(12-22)24-21(25)20-14-2-5-15(10-14)23-20/h3-4,6-9,14-16,20,23H,2,5,10-11H2,1H3,(H,24,25)/t14-,15+,16-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17.3	-44.3	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138138 (US8871783, 24) Show SMILES CC1(C)OC(=O)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C24H25N3O3S/c1-24(2)19-7-4-13(10-18(19)23(29)30-24)20-8-6-17(31-20)11-16(12-25)27-22(28)21-14-3-5-15(9-14)26-21/h4,6-8,10,14-16,21,26H,3,5,9,11H2,1-2H3,(H,27,28)/t14-,15+,16-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21.9	-43.7	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138132 (US8871783, 18) Show SMILES O=C(N[C@@H](Cc1ccc(s1)-c1cnn(CC2CCOCC2)c1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2 |r| Show InChI InChI=1S/C23H29N5O2S/c24-11-19(27-23(29)22-16-1-2-18(9-16)26-22)10-20-3-4-21(31-20)17-12-25-28(14-17)13-15-5-7-30-8-6-15/h3-4,12,14-16,18-19,22,26H,1-2,5-10,13H2,(H,27,29)/t16-,18+,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	27	-43.2	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138124 (US8871783, 10) Show SMILES Brc1ccc2sc(CC(NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)cc2c1 |r| Show InChI InChI=1S/C18H18BrN3OS/c19-12-2-4-16-11(5-12)7-15(24-16)8-14(9-20)22-18(23)17-10-1-3-13(6-10)21-17/h2,4-5,7,10,13-14,17,21H,1,3,6,8H2,(H,22,23)/t10-,13+,14?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	35.8	-42.5	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138134 (US8871783, 20) Show SMILES CN1CCC(CC1)c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r| Show InChI InChI=1S/C20H28N4OS/c1-24-8-6-13(7-9-24)18-5-4-17(26-18)11-16(12-21)23-20(25)19-14-2-3-15(10-14)22-19/h4-5,13-16,19,22H,2-3,6-11H2,1H3,(H,23,25)/t14-,15+,16-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	37.9	-42.4	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138121 (US8871783, 7) Show SMILES Fc1cc(ccc1C#N)-c1ccc2oc(CC(NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)cc2c1 |r| Show InChI InChI=1S/C25H21FN4O2/c26-22-10-15(1-2-17(22)12-27)14-4-6-23-18(7-14)9-21(32-23)11-20(13-28)30-25(31)24-16-3-5-19(8-16)29-24/h1-2,4,6-7,9-10,16,19-20,24,29H,3,5,8,11H2,(H,30,31)/t16-,19+,20?,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	39.3	-42.3	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138129 (US8871783, 15) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1csc(CC(NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c1 |r| Show InChI InChI=1S/C23H24N4O2S/c1-27-20-8-13(2-3-14(20)9-21(27)28)16-7-19(30-12-16)10-18(11-24)26-23(29)22-15-4-5-17(6-15)25-22/h2-3,7-8,12,15,17-18,22,25H,4-6,9-10H2,1H3,(H,26,29)/t15-,17+,18?,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	41.9	-42.1	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138127 (US8871783, 13) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1csc(CC(NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c1F |r| Show InChI InChI=1S/C23H23FN4O2S/c1-28-18-7-12(2-3-13(18)8-20(28)29)17-11-31-19(21(17)24)9-16(10-25)27-23(30)22-14-4-5-15(6-14)26-22/h2-3,7,11,14-16,22,26H,4-6,8-9H2,1H3,(H,27,30)/t14-,15+,16?,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	61.7	-41.2	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138123 (US8871783, 9) Show SMILES O=C(NC(Cc1cc2cc(ccc2o1)-c1ccccc1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2 |r| Show InChI InChI=1S/C24H23N3O2/c25-14-20(27-24(28)23-17-6-8-19(11-17)26-23)13-21-12-18-10-16(7-9-22(18)29-21)15-4-2-1-3-5-15/h1-5,7,9-10,12,17,19-20,23,26H,6,8,11,13H2,(H,27,28)/t17-,19+,20?,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	62	-41.1	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138120 (US8871783, 6) Show SMILES Brc1ccc2oc(CC(NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)cc2c1 |r| Show InChI InChI=1S/C18H18BrN3O2/c19-12-2-4-16-11(5-12)7-15(24-16)8-14(9-20)22-18(23)17-10-1-3-13(6-10)21-17/h2,4-5,7,10,13-14,17,21H,1,3,6,8H2,(H,22,23)/t10-,13+,14?,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	64.1	-41.1	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138125 (US8871783, 11) Show SMILES O=C(NC(Cc1cc2cc(ccc2s1)-c1ccccc1)C#N)[C@H]1N[C@@H]2CC[C@H]1C2 |r| Show InChI InChI=1S/C24H23N3OS/c25-14-20(27-24(28)23-17-6-8-19(11-17)26-23)13-21-12-18-10-16(7-9-22(18)29-21)15-4-2-1-3-5-15/h1-5,7,9-10,12,17,19-20,23,26H,6,8,11,13H2,(H,27,28)/t17-,19+,20?,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	72.8	-40.7	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138122 (US8871783, 8) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1ccc2oc(CC(NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)cc2c1 |r| Show InChI InChI=1S/C27H26N4O3/c1-31-23-11-16(2-3-17(23)12-25(31)32)15-5-7-24-19(8-15)10-22(34-24)13-21(14-28)30-27(33)26-18-4-6-20(9-18)29-26/h2-3,5,7-8,10-11,18,20-21,26,29H,4,6,9,12-13H2,1H3,(H,30,33)/t18-,20+,21?,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	104	-39.9	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM138119 (US8871783, 5) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)o1 |r| Show InChI InChI=1S/C23H24N4O3/c1-27-19-9-14(3-2-13(19)10-21(27)28)20-7-6-18(30-20)11-17(12-24)26-23(29)22-15-4-5-16(8-15)25-22/h2-3,6-7,9,15-17,22,25H,4-5,8,10-11H2,1H3,(H,26,29)/t15-,16+,17-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	177	-38.5	n/a	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmBh US Patent					Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...				US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50026017 (2-Amino-N-(benzyl-cyano-methyl)-acetamide | CHEMBL...) Show SMILES NCC(=O)NC(Cc1ccccc1)C#N Show InChI InChI=1S/C11H13N3O/c12-7-10(14-11(15)8-13)6-9-4-2-1-3-5-9/h1-5,10H,6,8,13H2,(H,14,15)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Mus musculus)	BDBM50147181 (3-{[1-(2-Amino-acetylamino)-3-methyl-butyl]-hydrox...) Show SMILES CC(C)CC(NC(=O)CN)P(O)(=O)CCC(O)=O Show InChI InChI=1S/C10H21N2O5P/c1-7(2)5-9(12-8(13)6-11)18(16,17)4-3-10(14)15/h7,9H,3-6,11H2,1-2H3,(H,12,13)(H,14,15)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay				Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Mus musculus)	BDBM50147182 (3-{[1-(2-Amino-acetylamino)-3-methyl-butyl]-hydrox...) Show SMILES COC(=O)CCP(O)(=O)C(CC(C)C)NC(=O)CN Show InChI InChI=1S/C11H23N2O5P/c1-8(2)6-10(13-9(14)7-12)19(16,17)5-4-11(15)18-3/h8,10H,4-7,12H2,1-3H3,(H,13,14)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay				Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Mus musculus)	BDBM50147183 (3-{[(2-Amino-acetylamino)-phenyl-methyl]-hydroxy-p...) Show SMILES NCC(=O)NC(c1ccccc1)P(O)(=O)CCC(O)=O Show InChI InChI=1S/C12H17N2O5P/c13-8-10(15)14-12(9-4-2-1-3-5-9)20(18,19)7-6-11(16)17/h1-5,12H,6-8,13H2,(H,14,15)(H,16,17)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.76E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay				Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50026018 (2-Amino-N-(1-benzyl-3-methanesulfonyl-allyl)-aceta...) Show SMILES CS(=O)(=O)\C=C\C(Cc1ccccc1)NC(=O)CN Show InChI InChI=1S/C13H18N2O3S/c1-19(17,18)8-7-12(15-13(16)10-14)9-11-5-3-2-4-6-11/h2-8,12H,9-10,14H2,1H3,(H,15,16)/b8-7+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Mus musculus)	BDBM50147185 (3-{[1-(2-Amino-acetylamino)-3-phenyl-propyl]-hydro...) Show SMILES NCC(=O)NC(CCc1ccccc1)P(O)(=O)CCC(O)=O Show InChI InChI=1S/C14H21N2O5P/c15-10-12(17)16-13(22(20,21)9-8-14(18)19)7-6-11-4-2-1-3-5-11/h1-5,13H,6-10,15H2,(H,16,17)(H,18,19)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.87E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay				Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Mus musculus)	BDBM50147180 (3-{[(2-Amino-acetylamino)-phenyl-methyl]-hydroxy-p...) Show SMILES COC(=O)CCP(O)(=O)C(NC(=O)CN)c1ccccc1 Show InChI InChI=1S/C13H19N2O5P/c1-20-12(17)7-8-21(18,19)13(15-11(16)9-14)10-5-3-2-4-6-10/h2-6,13H,7-9,14H2,1H3,(H,15,16)(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.88E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay				Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50026015 (4-(2-Amino-acetylamino)-5-phenyl-pent-2-enoic acid...) Show SMILES COC(=O)\C=C\C(Cc1ccccc1)NC(=O)CN Show InChI InChI=1S/C14H18N2O3/c1-19-14(18)8-7-12(16-13(17)10-15)9-11-5-3-2-4-6-11/h2-8,12H,9-10,15H2,1H3,(H,16,17)/b8-7+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of Dipeptidyl aminopeptidase 1				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Mus musculus)	BDBM50147184 (3-{[1-(2-Amino-acetylamino)-3-phenyl-propyl]-hydro...) Show SMILES COC(=O)CCP(O)(=O)C(CCc1ccccc1)NC(=O)CN Show InChI InChI=1S/C15H23N2O5P/c1-22-15(19)9-10-23(20,21)14(17-13(18)11-16)8-7-12-5-3-2-4-6-12/h2-6,14H,7-11,16H2,1H3,(H,17,18)(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.12E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay				Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Mus musculus)	BDBM50147187 (3-{[1-(2-Amino-acetylamino)-2-phenyl-ethyl]-hydrox...) Show SMILES NCC(=O)NC(Cc1ccccc1)P(O)(=O)CCC(O)=O Show InChI InChI=1S/C13H19N2O5P/c14-9-11(16)15-12(8-10-4-2-1-3-5-10)21(19,20)7-6-13(17)18/h1-5,12H,6-9,14H2,(H,15,16)(H,17,18)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.29E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay				Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Mus musculus)	BDBM50147186 (3-{[1-(2-Amino-acetylamino)-2-phenyl-ethyl]-hydrox...) Show SMILES COC(=O)CCP(O)(=O)C(Cc1ccccc1)NC(=O)CN Show InChI InChI=1S/C14H21N2O5P/c1-21-14(18)7-8-22(19,20)13(16-12(17)10-15)9-11-5-3-2-4-6-11/h2-6,13H,7-10,15H2,1H3,(H,16,17)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.14E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Compound was evaluated to inhibit cathepsin C (Dipeptidyl peptidase I) in non competitive binding assay				Bioorg Med Chem Lett 14: 3113-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.028 BindingDB Entry DOI: 10.7270/Q26Q1XT1
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50026027 (2-(2-Amino-acetylamino)-3-phenyl-propionamide | CH...) Show SMILES NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C11H15N3O2/c12-7-10(15)14-9(11(13)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H2,13,16)(H,14,15)/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	6.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for Inhibition of dipeptidyl Dipeptidyl aminopeptidase 1				J Med Chem 29: 104-11 (1986) BindingDB Entry DOI: 10.7270/Q2542MKC
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) Show SMILES CN1CCC2(CC1)C(=O)Nc1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-10-8-29(9-11-35)23-14-17(5-7-25(23)34-28(29)37)18-2-3-19(24(30)15-18)12-22(16-31)33-27(36)26-20-4-6-21(13-20)32-26/h2-3,5,7,14-15,20-22,26,32H,4,6,8-13H2,1H3,(H,33,36)(H,34,37)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) Show SMILES CN1CCC2(CC1)C(=O)Nc1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-10-8-29(9-11-35)23-14-17(5-7-25(23)34-28(29)37)18-2-3-19(24(30)15-18)12-22(16-31)33-27(36)26-20-4-6-21(13-20)32-26/h2-3,5,7,14-15,20-22,26,32H,4,6,8-13H2,1H3,(H,33,36)(H,34,37)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) Show SMILES CN1CCC2(CC1)C(=O)Nc1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-10-8-29(9-11-35)23-14-17(5-7-25(23)34-28(29)37)18-2-3-19(24(30)15-18)12-22(16-31)33-27(36)26-20-4-6-21(13-20)32-26/h2-3,5,7,14-15,20-22,26,32H,4,6,8-13H2,1H3,(H,33,36)(H,34,37)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50195247 (CHEMBL3936580) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1ccc(C[C@H](NC(=O)C2(N)CCOCC2)C#N)cc1 |r| Show InChI InChI=1S/C24H26N4O3/c1-28-21-13-18(6-7-19(21)14-22(28)29)17-4-2-16(3-5-17)12-20(15-25)27-23(30)24(26)8-10-31-11-9-24/h2-7,13,20H,8-12,14,26H2,1H3,(H,27,30)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.251	n/a	n/a	n/a	n/a	n/a	n/a
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assay				J Med Chem 59: 9457-9472 (2016) Article DOI: 10.1021/acs.jmedchem.6b01127 BindingDB Entry DOI: 10.7270/Q2Z321K4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM633586 (N—((S)-1-cyano-2-(3-fluoro-4′-(pentafluoro-1...) Show SMILES CO[C@@H]1CNC[C@H](OC1)C(=O)N[C@@H](Cc1ccc(cc1F)-c1ccc(cc1)S(F)(F)(F)(F)F)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H30FN5O2/c29-23-14-17(16-4-6-24-22(13-16)28(27(36)34-24)7-9-31-10-8-28)1-2-18(23)11-21(15-30)33-26(35)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,35)(H,34,36)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50310682 ((S)-2-amino-N-((S)-1-cyano-2-(5-phenylthiophen-2-y...) Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](Cc1ccc(s1)-c1ccccc1)C#N |r| Show InChI InChI=1S/C20H19N3OS2/c21-13-15(23-20(24)18(22)12-16-7-4-10-25-16)11-17-8-9-19(26-17)14-5-2-1-3-6-14/h1-10,15,18H,11-12,22H2,(H,23,24)/t15-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada& Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C				Bioorg Med Chem Lett 19: 5392-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.114 BindingDB Entry DOI: 10.7270/Q298874W
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H30FN5O2/c29-23-14-17(16-4-6-24-22(13-16)28(27(36)34-24)7-9-31-10-8-28)1-2-18(23)11-21(15-30)33-26(35)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,35)(H,34,36)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H30FN5O2/c29-23-14-17(16-4-6-24-22(13-16)28(27(36)34-24)7-9-31-10-8-28)1-2-18(23)11-21(15-30)33-26(35)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,35)(H,34,36)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502619 (CHEMBL4561264) Show SMILES CS[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| Show InChI InChI=1S/C22H22N4OS/c1-28-20-11-21(25-14-20)22(27)26-19(13-24)10-15-2-6-17(7-3-15)18-8-4-16(12-23)5-9-18/h2-9,19-21,25H,10-11,14H2,1H3,(H,26,27)/t19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.398	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-25-7-5-17(14-23(25)29(28(35)37)8-10-32-11-9-29)18-2-3-19(24(30)15-18)12-22(16-31)34-27(36)26-20-4-6-21(13-20)33-26/h2-3,5,7,14-15,20-22,26,32-33H,4,6,8-13H2,1H3,(H,34,36)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-25-7-5-17(14-23(25)29(28(35)37)8-10-32-11-9-29)18-2-3-19(24(30)15-18)12-22(16-31)34-27(36)26-20-4-6-21(13-20)33-26/h2-3,5,7,14-15,20-22,26,32-33H,4,6,8-13H2,1H3,(H,34,36)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair

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