Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cell division protein FtsZ (Staphylococcus aureus) | BDBM50079356 (CHEMBL511201) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cell division protein FtsZ (Staphylococcus aureus) | BDBM50079356 (CHEMBL511201) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cell division protein FtsZ (Staphylococcus aureus) | BDBM50079356 (CHEMBL511201) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a | n/a |
Prolysis Curated by ChEMBL | Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity | Science 321: 1673-5 (2008) Article DOI: 10.1126/science.1159961 BindingDB Entry DOI: 10.7270/Q2HX1GG1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cell division protein FtsZ (Staphylococcus aureus) | BDBM50079356 (CHEMBL511201) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a | n/a |
Stony Brook University Curated by ChEMBL | Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity | Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM25525 (24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Bacillus subtilis) | BDBM25525 (24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of FtsZ in Bacillus subtilis assessed as disruption of Z ring formation | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113480 BindingDB Entry DOI: 10.7270/Q2474FP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50203065 (3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 5.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50335238 (5-Benzamido-2-cyclohexyl-6-N,N-diethylamino-1H-ben...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 6.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization | J Med Chem 54: 374-81 (2011) Article DOI: 10.1021/jm1012006 BindingDB Entry DOI: 10.7270/Q26W9C29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50203065 (3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 6.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ polymerization | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50335239 (CHEMBL1651202 | butyl 2-cyclohexyl-6-(diethylamino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 7.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization | J Med Chem 54: 374-81 (2011) Article DOI: 10.1021/jm1012006 BindingDB Entry DOI: 10.7270/Q26W9C29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50079361 (CHEMBL3416824) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086108 (CHEMBL3425702) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50439495 (CHEMBL2418095) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Aquifex aeolicus) | BDBM81331 (MeGTP (6b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | 3.33 | n/a | n/a | n/a | 7.5 | n/a |
University of Amsterdam | Assay Description The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph... | Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50203126 (3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Stony Brook University Curated by ChEMBL | Assay Description Inhibition of recombinant Escherichia coli K12 FtsZ assembly by light-scattering assay | Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Staphylococcus aureus) | BDBM50203126 (3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50079359 (Viriditoxin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50079358 (CHEMBL3416948) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50079359 (Viriditoxin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ polymerization | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50079360 (CHEBI:69681 | Dichamanetin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM25525 (24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of FtsZ in Escherichia coli assessed as disruption of Z ring formation | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113480 BindingDB Entry DOI: 10.7270/Q2474FP4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086088 (CHEMBL3425706) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Aquifex aeolicus) | BDBM81332 (PyrrGTP (7b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | 15.6 | n/a | n/a | n/a | 7.5 | n/a |
University of Amsterdam | Assay Description The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph... | Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Aquifex aeolicus) | BDBM81331 (MeGTP (6b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.53E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Amsterdam | Assay Description The binding affinities to FtsZ were determined by a fluorescent coupled assay for phosphate relase. In this GTPase studies, phosphate liberated durin... | Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50203126 (3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Stony Brook University Curated by ChEMBL | Assay Description Inhibition of recombinant Escherichia coli K12 FtsZ GTPase activity by malachite green sodium molybdate assay | Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359406 (CHEMBL1926717) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359412 (CHEMBL1926724) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359407 (CHEMBL1926719) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Aquifex aeolicus) | BDBM81332 (PyrrGTP (7b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.14E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Amsterdam | Assay Description The binding affinities to FtsZ were determined by a fluorescent coupled assay for phosphate relase. In this GTPase studies, phosphate liberated durin... | Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086098 (CHEMBL3425705) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Bacillus subtilis) | BDBM50392993 (TOTAROL) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity by enzyme-coupled assay | ACS Med Chem Lett 3: 818-822 (2012) Article DOI: 10.1021/ml3001775 BindingDB Entry DOI: 10.7270/Q2XG9S7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086206 (CHEMBL3425606) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086123 (CHEMBL3425694) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359400 (CHEMBL1929425) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086124 (CHEMBL3425693) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359410 (CHEMBL1926722) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086201 (CHEMBL3425611) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359413 (CHEMBL1926725) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Bacillus subtilis) | BDBM50067040 (((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Pharmaceutical Education and Research Curated by ChEMBL | Assay Description Inhibition of Bacillus subtilis FtsZ polymerization | Eur J Med Chem 45: 4209-14 (2010) Article DOI: 10.1016/j.ejmech.2010.06.015 BindingDB Entry DOI: 10.7270/Q28G8KWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086200 (CHEMBL3425612) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50086203 (CHEMBL3425609) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay | ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359411 (CHEMBL1926723) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359398 (CHEMBL110168) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359401 (CHEMBL1929426) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359408 (CHEMBL1926720) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Aquifex aeolicus) | BDBM81333 (ClGTP (4b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | 77 | n/a | n/a | n/a | 7.5 | n/a |
University of Amsterdam | Assay Description The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph... | Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50439496 (CHEMBL2418096 | US9169182, J23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | 6.5 | 25 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION US Patent | Assay Description The bacterial cytoskeletal protein FtsZ is a GTPase and has structural homology to the eukaryotic cytoskeletal protein tubulin, but lacks significant... | US Patent US9169182 (2015) BindingDB Entry DOI: 10.7270/Q22Z149Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Aquifex aeolicus) | BDBM81335 (BrGTP (5b)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70E+4 | 126 | n/a | n/a | n/a | 7.5 | n/a |
University of Amsterdam | Assay Description The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph... | Chem Biol 15: 189-99 (2008) Article DOI: 10.1016/j.chembiol.2007.12.013 BindingDB Entry DOI: 10.7270/Q2P849CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Escherichia coli) | BDBM50439496 (CHEMBL2418096 | US9169182, J23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli FtsZ GTPase activity | Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division protein FtsZ (Staphylococcus aureus) | BDBM50201769 (CHEMBL3416823) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 3.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair |
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