Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 3.84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 5.69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Ability of the compound to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluated | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50207593 ((S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHEN...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 32.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426290 (CHEMBL2312682) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50088216 (CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Compound was tested for binding affinity against human Ionotropic glutamate receptor ionotropic kainate 3 in HEK293 cells using [3H]-kainate as radio... | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50116040 ((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252051 ((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 57.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426285 (CHEMBL2312403) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50591738 (CHEMBL5193862) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | 142 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2021.114085 BindingDB Entry DOI: 10.7270/Q2XW4PS2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426296 (CHEMBL2312396) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50126764 ((S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid UniChem Similars | Article PubMed | 199 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426291 (CHEMBL2312681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 217 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426289 (CHEMBL2312683) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 239 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426288 (CHEMBL2312684) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50240399 ((2R,3R,4S)-3-(carboxymethyl)-4-isopropylpyrrolidin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 376 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat cloned iGluR7 | J Med Chem 51: 4085-92 (2008) Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50240399 ((2R,3R,4S)-3-(carboxymethyl)-4-isopropylpyrrolidin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 376 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50088197 (CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 423 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Ability of the compound to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluated | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat iGluR7 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 494 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 494 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50091474 ((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 518 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50116044 (CHEMBL416685 | {6-Nitro-2,3-dioxo-7-[3-(4-phenyl-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 617 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50088222 ((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 617 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Ability of the compound to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluated | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50116042 (CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM26431 ((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 789 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Ability of the compound to bind to Ionotropic glutamate receptor ionotropic kainate 3 was evaluated | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 789 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 3 using cell membranes prepared from HEK293 cell... | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252048 ((2S,4R)-2-amino-4-(3-methoxy-3-oxopropyl)pentanedi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50349983 (CHEMBL1812596) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50591736 (CHEMBL5173718) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2021.114085 BindingDB Entry DOI: 10.7270/Q2XW4PS2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50591735 (CHEMBL5209119) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2021.114085 BindingDB Entry DOI: 10.7270/Q2XW4PS2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50295042 ((S)-2-Amino-3-((RS)-3-hydroxy-8-methyl-7,8-dihydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50116047 ((6-Nitro-2,3-dioxo-7-{3-[(3-phenyl-propylamino)-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50116048 (CHEMBL67828 | {6-Nitro-2,3-dioxo-7-[3-(4-phenethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50034501 ((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cells | J Med Chem 53: 8354-8361 (2010) Article DOI: 10.1021/jm101218a BindingDB Entry DOI: 10.7270/Q20Z73HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50263220 (CHEMBL4075364) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Biotechnology, Chemistry and Pharmacy, (DoE 2018-2022) NatSynDrugs , University of Siena , Via A. Moro 2 , 53100 Siena , Italy. Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from recombinant homomeric rat GluK3 receptor expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 61: 2124-2130 (2018) Article DOI: 10.1021/acs.jmedchem.8b00099 BindingDB Entry DOI: 10.7270/Q2WS8WQT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50116043 (3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand | Bioorg Med Chem Lett 12: 2113-6 (2002) BindingDB Entry DOI: 10.7270/Q22806XK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426286 (CHEMBL2312686) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50126763 ((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 2.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426292 (CHEMBL2312402) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252050 ((2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50591737 (CHEMBL5206048) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2021.114085 BindingDB Entry DOI: 10.7270/Q2XW4PS2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252052 ((2S,4R)-2-amino-4-(3-(ethylamino)-3-oxopropyl)pent...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252920 ((S)-1-[2'-Amino-2'-carboxyethyl]-5,7-dihydrothieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426294 (CHEMBL2312399) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252922 ((S)-1-(2'-Amino-2'-carboxyethyl)thieno[3,2-d]pyrim...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair |
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