Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139926 (US8901087, 2) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.0500 | -58.8 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481715 (US10913733, Example 26) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481707 (N-(5-((4-(4-(N,N- dimethylsulfamoyl) benzylidene)p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM77064 (US9695197, 4) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.110 | -56.8 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9695197 (2017) BindingDB Entry DOI: 10.7270/Q247481J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481720 (US10913733, Example 31) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.117 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139933 (US8901087, 27) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.120 | -56.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM177755 (US9120781, 18) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.130 | -56.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Simon Fraser University; Merck Sharp & Dohme Corp.; Alectos Therapeutics Inc. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US9120781 (2015) BindingDB Entry DOI: 10.7270/Q2DZ072S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM179374 (US9126957, 10) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.140 | -56.2 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
MERCK SHARP & DOHME CORP.; ALECTOS THERAPEUTICS, INC. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US9126957 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139959 (US8901087, 191) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.140 | -56.2 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139951 (US8901087, 95) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.160 | -55.9 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM314813 ((3aR,5S,6S,7R,7aR)-5-((R)-1-(4- benzylbenzyloxy)-2...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ALECTOS THERAPEUTICS, INC.; MERCK SHARP & DOHME CORP. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9611275 (2017) BindingDB Entry DOI: 10.7270/Q2833V4D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481715 (US10913733, Example 26) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.167 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139925 (US8901087, 1) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.170 | -55.8 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139952 (US8901087, 97) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.170 | -55.8 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139946 (US8901087, 76) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.180 | -55.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM314809 ((3aR,5S,6S,7R,7aR)-2-(dimethylamino)-5-((R)-1-meth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ALECTOS THERAPEUTICS, INC.; MERCK SHARP & DOHME CORP. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9611275 (2017) BindingDB Entry DOI: 10.7270/Q2833V4D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM46008 (US8901087, 96) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.190 | -55.5 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM177758 (US9120781, 26) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | -55.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Simon Fraser University; Merck Sharp & Dohme Corp.; Alectos Therapeutics Inc. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US9120781 (2015) BindingDB Entry DOI: 10.7270/Q2DZ072S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139941 (US8901087, 63) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.220 | -55.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481739 (US10913733, Example 50) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.241 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM179370 (US9126957, 6) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.260 | -54.7 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
MERCK SHARP & DOHME CORP.; ALECTOS THERAPEUTICS, INC. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US9126957 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM179366 (US9126957, 2) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.260 | -54.7 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
MERCK SHARP & DOHME CORP.; ALECTOS THERAPEUTICS, INC. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US9126957 (2015) BindingDB Entry DOI: 10.7270/Q2DV1HN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481711 (N-(5-((4-((1-oxoisoindolin- 5-yl)methylene)piperid...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.268 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481727 ((S,Z)-N-(5-((4-(4- methoxybenzylidene)-2- methylpi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.287 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481698 (4-((1-((2-acetamidothiazol- 5-yl)methyl)-piperidin...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.294 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139930 (US8901087, 11) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | -54.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM240645 (US9409924, (3aR,5R,6R,7S,7aR)-2-(dimethylamino)-7-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | -54.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9409924 (2016) BindingDB Entry DOI: 10.7270/Q26H4G90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM205418 (US9243020, (3aR,5R,6S,7R,7aR)-2-(ethylamino)-5-(hy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 0.300 | -54.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9243020 (2016) BindingDB Entry DOI: 10.7270/Q2542MD4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM240657 (US9409924, 34) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | -54.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9409924 (2016) BindingDB Entry DOI: 10.7270/Q26H4G90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM205418 (US9243020, (3aR,5R,6S,7R,7aR)-2-(ethylamino)-5-(hy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9815861 (2017) BindingDB Entry DOI: 10.7270/Q2R78HJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481718 (US10913733, Example 29) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.324 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139939 (US8901087, 57) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.330 | -54.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM50513934 (CHEMBL4443587) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of recombinant human OGA | J Med Chem 62: 10062-10097 (2019) Article DOI: 10.1021/acs.jmedchem.9b01090 BindingDB Entry DOI: 10.7270/Q21G0QMH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481697 (N-(5-((4-((1H-pyrazol-4- yl)methylene)piperidin-1-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.387 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481741 (US10913733, Example 52 | US10913733, Example 54) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.389 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481600 (US10913733, Example 1) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.392 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM240644 (US9409924, (3aR,5R,6R,7S,7aR)-2-(ethylamino)-7-flu...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | -53.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9409924 (2016) BindingDB Entry DOI: 10.7270/Q26H4G90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM50323697 ((3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB US Patent | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9815861 (2017) BindingDB Entry DOI: 10.7270/Q2R78HJ8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139931 (US8901087, 13) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.400 | -53.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM50323697 ((3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB US Patent | 0.400 | -53.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9243020 (2016) BindingDB Entry DOI: 10.7270/Q2542MD4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM50323697 ((3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB US Patent | 0.400 | -53.6 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9695197 (2017) BindingDB Entry DOI: 10.7270/Q247481J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM50323697 ((3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of recombinant human OGA | J Med Chem 62: 10062-10097 (2019) Article DOI: 10.1021/acs.jmedchem.9b01090 BindingDB Entry DOI: 10.7270/Q21G0QMH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481716 (US10913733, Example 27) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.411 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481708 (N-(5-{[4-(1H-indol-5- ylmethylidene)piperidin-1- y...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.427 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM481719 (US10913733, Example 30) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Experimental procedure for kinetic analyses: Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (p... | US Patent US10913733 (2021) BindingDB Entry DOI: 10.7270/Q29G5QXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139961 (US8901087, 211) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.440 | -53.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM314781 ((3aR,5S,6S,7R,7aR)-2- (dimethylamino)-5-((R)-2,2,2...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ALECTOS THERAPEUTICS, INC.; MERCK SHARP & DOHME CORP. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9611275 (2017) BindingDB Entry DOI: 10.7270/Q2833V4D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM139942 (US8901087, 65) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.450 | -53.3 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions are carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acety... | US Patent US8901087 (2014) BindingDB Entry DOI: 10.7270/Q24B301W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM205423 (US9243020, 17 | US9815861, Example 17) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.5 | -53.1 | n/a | n/a | n/a | n/a | n/a | 7.0 | 25 |
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9243020 (2016) BindingDB Entry DOI: 10.7270/Q2542MD4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein O-GlcNAcase (Homo sapiens (Human)) | BDBM205423 (US9243020, 17 | US9815861, Example 17) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp. US Patent | Assay Description Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet... | US Patent US9815861 (2017) BindingDB Entry DOI: 10.7270/Q2R78HJ8 | |||||||||||
More data for this Ligand-Target Pair |
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