BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1147,M628L,N654N,K657R,T802F,K807E]'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gag-Pol polyprotein [588-1147,M628L,N654N,K657R,T802F,K807E] (Human immunodeficiency virus type 1 group M subtyp...)	BDBM77092 (CMX-157 \| CMX157 \| HDP-tenofovir \| Tenofovir Exali...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Chimerix, Inc. US Patent					Assay Description The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...				US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT
Chimerix, Inc. US Patent					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1147,M628L,N654N,K657R,T802F,K807E] (Human immunodeficiency virus type 1 group M subtyp...)	BDBM77145 (9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	6.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chimerix, Inc. US Patent					Assay Description The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...				US Patent US9694024 (2017) BindingDB Entry DOI: 10.7270/Q2BV7DRT
Chimerix, Inc. US Patent					More data for this Ligand-Target Pair