Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 22 member 5 (Rattus norvegicus) | BDBM50375327 (CHEMBL410874) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Perugia Curated by ChEMBL | Assay Description Inhibition of rat kidney brush border membrane OCTN2 transporter assessed as [3H]carnitine uptake after 10 mins | Bioorg Med Chem 16: 1444-51 (2008) Article DOI: 10.1016/j.bmc.2007.10.053 BindingDB Entry DOI: 10.7270/Q21837CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 5 (Rattus norvegicus) | BDBM50375326 (CHEMBL260616) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Perugia Curated by ChEMBL | Assay Description Inhibition of rat kidney brush border membrane OCTN2 transporter assessed as [3H]carnitine uptake after 10 mins | Bioorg Med Chem 16: 1444-51 (2008) Article DOI: 10.1016/j.bmc.2007.10.053 BindingDB Entry DOI: 10.7270/Q21837CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 5 (Homo sapiens) | BDBM50103624 (40602 | CHEBI:3537 | Cefaloridine | Cephaloridine ...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical College of Georgia Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Carnitine uptake (Carnitine: 0.02 uM) in OCTN2-expressing HeLa cells | J Biol Chem 275: 1699-707 (2000) Article DOI: 10.1074/jbc.275.3.1699 BindingDB Entry DOI: 10.7270/Q2CF9SZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 5 (Rattus norvegicus) | BDBM50375328 (CHEMBL410276) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.43E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Perugia Curated by ChEMBL | Assay Description Inhibition of rat kidney brush border membrane OCTN2 transporter assessed as [3H]carnitine uptake after 10 mins | Bioorg Med Chem 16: 1444-51 (2008) Article DOI: 10.1016/j.bmc.2007.10.053 BindingDB Entry DOI: 10.7270/Q21837CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 5 (Homo sapiens) | BDBM50350470 (CEFEPIME | Maxipime) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical College of Georgia Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Carnitine uptake (Carnitine: 0.02 uM) in OCTN2-expressing HeLa cells | J Biol Chem 275: 1699-707 (2000) Article DOI: 10.1074/jbc.275.3.1699 BindingDB Entry DOI: 10.7270/Q2CF9SZ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 5 (Homo sapiens) | BDBM50485614 (Cefoselis) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.40E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical College of Georgia Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Carnitine uptake (Carnitine: 0.02 uM) in OCTN2-expressing HeLa cells | J Biol Chem 275: 1699-707 (2000) Article DOI: 10.1074/jbc.275.3.1699 BindingDB Entry DOI: 10.7270/Q2CF9SZ0 | |||||||||||
More data for this Ligand-Target Pair |