Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194499 (US9200020, Table 3 compound 8) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 50 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194496 (US9200020, Table 3 compound 5) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 300 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60890 (US9200020, Table 3 compound 5B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 700 | -36.5 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194502 (US9200020, Table 3 compound 11) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 900 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194501 (US9200020, Table 3 compound 10) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194492 (US9200020, Table 3 compound 1) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60894 (US9200020, Table 3 compound 9B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.60E+3 | -34.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194493 (US9200020, Table 3 compound 2) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194497 (US9200020, Table 3 compound 6) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60886 (US9200020, Table 3, Compound 1B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.10E+4 | -29.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194491 (US9200020, Table 1, Compound 2) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60897 (US9200020, Table 3 compound 11B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.30E+4 | -29.0 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60896 (US9200020, Table 3 compound 10B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.10E+4 | -27.8 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60887 (US9200020, Table 3, Compound 2B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.10E+4 | -27.8 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194500 (US9200020, Table 3 compound 9) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194498 (US9200020, Table 3 compound 7) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60893 (US9200020, Table 3 compound 8B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.10E+4 | -26.0 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194495 (US9200020, Table 3 compound 4) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.70E+4 | -25.7 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60892 (US9200020, Table 3 compound 7B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.78E+5 | -22.3 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM194494 (US9200020, Table 3 compound 3) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60891 (US9200020, Table 3 compound 6B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >2.30E+5 | >-21.6 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60888 (US9200020, Table 3, Compound 3B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >2.50E+5 | >-21.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine phosphoribosyltransferase (Plasmodium vivax) | BDBM60884 (US9200020, Table 1, Compound 2B) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >2.50E+5 | >-21.4 | n/a | n/a | n/a | n/a | n/a | n/a | 37 |
THE UNIVERSITY OF QUEENSLAND; INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. US Patent | Assay Description The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr... | US Patent US9200020 (2015) BindingDB Entry DOI: 10.7270/Q2TM78XB | |||||||||||
More data for this Ligand-Target Pair |