Compile Data Set for Download or QSAR

Found 98 hits Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor antagonist protein'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50331042 (2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI InChI=1S/C26H32N4O6S2/c27-21-9-10-37-38-15-22(26(36)28-14-18-4-2-1-3-17(18)12-24(33)34)30-23(32)13-19(29-25(21)35)11-16-5-7-20(31)8-6-16/h1-8,19,21-22,31H,9-15,27H2,(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t19-,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrate				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553093 (CHEMBL4762305) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(N)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrate				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553094 (CHEMBL4761376) Show SMILES N[C@H]1CNC(=O)CC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrate				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553090 (CHEMBL4744066) Show SMILES OC(=O)Cc1ccccc1CNC(=O)[C@@H]1CSSCCCCN[C@@H](Cc2ccc(O)cc2)CC(=O)N1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrate				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553092 (CHEMBL4753417) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(F)cc2)NC1=O)C(=O)NCc1ccccc1CC(N)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrate				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553095 (CHEMBL4745618) Show SMILES N[C@H]1CCC(=O)NCC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	674	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrate				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553096 (CHEMBL4787513) Show SMILES N[C@H]1CCNC(=O)CC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	887	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrate				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553091 (CHEMBL4778960) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1)C(=O)NCc1ccccc1CC(N)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrate				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529330 (CHEMBL4527760) Show SMILES CCCC[C@H](N)C(=O)NNc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H35N5O4/c1-2-3-12-26(32)30(38)36-35-24-16-14-22(15-17-24)29(37)34-28(31(39)40-20-21-9-5-4-6-10-21)18-23-19-33-27-13-8-7-11-25(23)27/h4-11,13-17,19,26,28,33,35H,2-3,12,18,20,32H2,1H3,(H,34,37)(H,36,38)/t26-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529329 (CHEMBL4560993) Show SMILES CCCC[C@H](N)C(=O)Nc1cccc(c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H34N4O4/c1-2-3-15-26(32)30(37)34-24-13-9-12-22(17-24)29(36)35-28(31(38)39-20-21-10-5-4-6-11-21)18-23-19-33-27-16-8-7-14-25(23)27/h4-14,16-17,19,26,28,33H,2-3,15,18,20,32H2,1H3,(H,34,37)(H,35,36)/t26-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529320 (CHEMBL4540943) Show SMILES CCCC[C@H](N)C(=O)NNc1cccc(c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H35N5O4/c1-2-3-15-26(32)30(38)36-35-24-13-9-12-22(17-24)29(37)34-28(31(39)40-20-21-10-5-4-6-11-21)18-23-19-33-27-16-8-7-14-25(23)27/h4-14,16-17,19,26,28,33,35H,2-3,15,18,20,32H2,1H3,(H,34,37)(H,36,38)/t26-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529322 (CHEMBL4466281) Show SMILES CCCC[C@H](N)C(=O)Nc1cc(ccn1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C30H33N5O4/c1-2-3-12-24(31)29(37)35-27-17-21(14-15-32-27)28(36)34-26(30(38)39-19-20-9-5-4-6-10-20)16-22-18-33-25-13-8-7-11-23(22)25/h4-11,13-15,17-18,24,26,33H,2-3,12,16,19,31H2,1H3,(H,34,36)(H,32,35,37)/t24-,26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529326 (CHEMBL4557197) Show SMILES Oc1cccn(CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)OCc2ccccc2)c1=O |r| Show InChI InChI=1S/C25H23N3O5/c29-22-11-6-12-28(24(22)31)15-23(30)27-21(25(32)33-16-17-7-2-1-3-8-17)13-18-14-26-20-10-5-4-9-19(18)20/h1-12,14,21,26,29H,13,15-16H2,(H,27,30)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529328 (CHEMBL4475441) Show SMILES COc1cccn(CC(=O)NCCc2ccc(cc2)-c2ccccc2)c1=S Show InChI InChI=1S/C22H22N2O2S/c1-26-20-8-5-15-24(22(20)27)16-21(25)23-14-13-17-9-11-19(12-10-17)18-6-3-2-4-7-18/h2-12,15H,13-14,16H2,1H3,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529324 (CHEMBL4445197) Show SMILES Oc1cccn(CC(=O)NCCc2ccc(cc2)-c2ccccc2)c1=O Show InChI InChI=1S/C21H20N2O3/c24-19-7-4-14-23(21(19)26)15-20(25)22-13-12-16-8-10-18(11-9-16)17-5-2-1-3-6-17/h1-11,14,24H,12-13,15H2,(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529325 (CHEMBL4436776) Show SMILES CC(C)[C@H](NC(=O)Cn1cccc(O)c1=O)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C19H22N2O5/c1-13(2)17(19(25)26-12-14-7-4-3-5-8-14)20-16(23)11-21-10-6-9-15(22)18(21)24/h3-10,13,17,22H,11-12H2,1-2H3,(H,20,23)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50245396 (CHEMBL4101200) Show SMILES N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC#C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C24H30N3O4P/c1-2-9-20(17-32(30,31)22(25)15-14-18-10-5-3-6-11-18)24(29)27-21(23(26)28)16-19-12-7-4-8-13-19/h1,3-8,10-13,20-22H,9,14-17,25H2,(H2,26,28)(H,27,29)(H,30,31)/t20-,21+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assay				Bioorg Med Chem Lett 29: 1031-1042 (2019) Article DOI: 10.1016/j.bmcl.2019.02.034 BindingDB Entry DOI: 10.7270/Q2DR2ZSK
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50331042 (2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI InChI=1S/C26H32N4O6S2/c27-21-9-10-37-38-15-22(26(36)28-14-18-4-2-1-3-17(18)12-24(33)34)30-23(32)13-19(29-25(21)35)11-16-5-7-20(31)8-6-16/h1-8,19,21-22,31H,9-15,27H2,(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t19-,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Scientific Research Demokritos Curated by ChEMBL					Assay Description Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Leu-AMC as substrate incubated for 2 hrs by fluorescence based assay				ACS Med Chem Lett 11: 1429-1434 (2020) Article DOI: 10.1021/acsmedchemlett.0c00172 BindingDB Entry DOI: 10.7270/Q2WM1J0W
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601034 (CHEMBL5191661) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)COc1ccc(O)cc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50505155 (CHEMBL4455644) Show SMILES CC(C)CC(CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C64H93N16O12P/c1-40(2)29-45(37-93(91,92)55(67)26-25-42-17-7-4-8-18-42)58(84)75-49(24-14-16-28-66)59(85)78-53(33-47-35-70-39-72-47)63(89)79-52(32-46-34-69-38-71-46)60(86)73-41(3)57(83)76-50(30-43-19-9-5-10-20-43)62(88)80-54(36-81)64(90)77-51(31-44-21-11-6-12-22-44)61(87)74-48(56(68)82)23-13-15-27-65/h4-12,17-22,34-35,38-41,45,48-55,81H,13-16,23-33,36-37,65-67H2,1-3H3,(H2,68,82)(H,69,71)(H,70,72)(H,73,86)(H,74,87)(H,75,84)(H,76,83)(H,77,90)(H,78,85)(H,79,89)(H,80,88)(H,91,92)/t41-,45?,48-,49-,50-,51-,52-,53-,54-,55+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assay				Bioorg Med Chem Lett 29: 1031-1042 (2019) Article DOI: 10.1016/j.bmcl.2019.02.034 BindingDB Entry DOI: 10.7270/Q2DR2ZSK
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601033 (CHEMBL5209483) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(O)cc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50331042 (2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI InChI=1S/C26H32N4O6S2/c27-21-9-10-37-38-15-22(26(36)28-14-18-4-2-1-3-17(18)12-24(33)34)30-23(32)13-19(29-25(21)35)11-16-5-7-20(31)8-6-16/h1-8,19,21-22,31H,9-15,27H2,(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t19-,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Scientific Research Demokritos Curated by ChEMBL					Assay Description Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Arg-AMC as substrate incubated for 2 hrs by fluorescence based assay				ACS Med Chem Lett 11: 1429-1434 (2020) Article DOI: 10.1021/acsmedchemlett.0c00172 BindingDB Entry DOI: 10.7270/Q2WM1J0W
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50331042 (2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI InChI=1S/C26H32N4O6S2/c27-21-9-10-37-38-15-22(26(36)28-14-18-4-2-1-3-17(18)12-24(33)34)30-23(32)13-19(29-25(21)35)11-16-5-7-20(31)8-6-16/h1-8,19,21-22,31H,9-15,27H2,(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t19-,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601042 (CHEMBL5195885) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)COc1cc(F)c(F)c(F)c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50505150 (CHEMBL4537224) Show SMILES N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CCC(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C36H42N3O4P/c37-34(24-21-27-13-5-1-6-14-27)44(42,43)26-31(36(41)39-33(35(38)40)25-28-15-7-2-8-16-28)22-23-32(29-17-9-3-10-18-29)30-19-11-4-12-20-30/h1-20,31-34H,21-26,37H2,(H2,38,40)(H,39,41)(H,42,43)/t31-,33+,34-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assay				Bioorg Med Chem Lett 29: 1031-1042 (2019) Article DOI: 10.1016/j.bmcl.2019.02.034 BindingDB Entry DOI: 10.7270/Q2DR2ZSK
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553093 (CHEMBL4762305) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(N)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Mus musculus)	BDBM50077028 (CHEMBL3416692) Show SMILES CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H35N5O4/c1-2-3-12-25(33)30(38)35-27-16-21(14-15-24(27)32)29(37)36-28(31(39)40-19-20-9-5-4-6-10-20)17-22-18-34-26-13-8-7-11-23(22)26/h4-11,13-16,18,25,28,34H,2-3,12,17,19,32-33H2,1H3,(H,35,38)(H,36,37)/t25-,28-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Scientific Research"Demokritos" Curated by ChEMBL					Assay Description Inhibition of mouse recombinant IRAP using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assay				J Med Chem 58: 1524-43 (2015) Article DOI: 10.1021/jm501867s BindingDB Entry DOI: 10.7270/Q2Z321B0
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601035 (CHEMBL5194003) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601032 (CHEMBL5183817) Show SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(O)cc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601040 (CHEMBL5195928) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1cccc(Cl)c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601031 (CHEMBL5199194) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM85550 (Ang IV | CAS_12676-15-2 | CHEMBL261120 | cid_12381...) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C40H54N8O8/c1-5-24(4)34(47-35(50)29(44-37(52)33(41)23(2)3)18-26-13-15-28(49)16-14-26)38(53)45-30(20-27-21-42-22-43-27)39(54)48-17-9-12-32(48)36(51)46-31(40(55)56)19-25-10-7-6-8-11-25/h6-8,10-11,13-16,21-24,29-34,49H,5,9,12,17-20,41H2,1-4H3,(H,42,43)(H,44,52)(H,45,53)(H,46,51)(H,47,50)(H,55,56)/t24-,29-,30-,31-,32-,33-,34-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Scientific Research Demokritos Curated by ChEMBL					Assay Description Inhibition of human IRAP soluble domain expressed in HEK293S GnTI(-) cells using Leu-AMC as substrate incubated for 2 hrs by fluorescence based assay				ACS Med Chem Lett 11: 1429-1434 (2020) Article DOI: 10.1021/acsmedchemlett.0c00172 BindingDB Entry DOI: 10.7270/Q2WM1J0W
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601034 (CHEMBL5191661) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)COc1ccc(O)cc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601045 (CHEMBL5209535) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CN[C@@H](Cc1ccc(O)cc1)C(=O)OC |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601025 (CHEMBL5207828) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601057 (CHEMBL5171198) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCN[C@@H](Cc1ccc(O)cc1)C(=O)OC |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553092 (CHEMBL4753417) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(F)cc2)NC1=O)C(=O)NCc1ccccc1CC(N)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601037 (CHEMBL5200376) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCOc1cccc(O)c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601041 (CHEMBL5197001) Show SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1cccc(Cl)c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601030 (CHEMBL5185614) Show SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(OCc2ccccc2)cc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601029 (CHEMBL5194823) Show SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCCCO |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601036 (CHEMBL5184077) Show SMILES COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1cccc(O)c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601026 (CHEMBL5202569) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553095 (CHEMBL4745618) Show SMILES N[C@H]1CCC(=O)NCC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553096 (CHEMBL4787513) Show SMILES N[C@H]1CCNC(=O)CC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601056 (CHEMBL5189714) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCN(C)CCO |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601055 (CHEMBL5182525) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCNCCO |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50601028 (CHEMBL5174528) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00904 BindingDB Entry DOI: 10.7270/Q2222ZVG
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50553091 (CHEMBL4778960) Show SMILES N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1)C(=O)NCc1ccccc1CC(N)=O |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...				Citation and Details Article DOI: 10.1039/c9md00485h BindingDB Entry DOI: 10.7270/Q2377DB2
					More data for this Ligand-Target Pair
Interleukin-1 receptor antagonist protein (Homo sapiens)	BDBM50529330 (CHEMBL4527760) Show SMILES CCCC[C@H](N)C(=O)NNc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H35N5O4/c1-2-3-12-26(32)30(38)36-35-24-16-14-22(15-17-24)29(37)34-28(31(39)40-20-21-9-5-4-6-10-21)18-23-19-33-27-13-8-7-11-25(23)27/h4-11,13-17,19,26,28,33,35H,2-3,12,18,20,32H2,1H3,(H,34,37)(H,36,38)/t26-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Centre for Scientific Research "Demokritos" Curated by ChEMBL					Assay Description Inhibition of human recombinant IRAP expressed in baculovirus infected Sf9 cells using omniMMP fluorogenic substrate incubated for 5 to 10 mins by fl...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115177 BindingDB Entry DOI: 10.7270/Q2FN19NT
					More data for this Ligand-Target Pair

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