Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin beta-3 (Mus musculus) | BDBM50083811 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bradford Curated by ChEMBL | Assay Description Antagonist activity at mouse endothelial alpha2bbeta3 integrin receptor by cell adhesion assay | J Med Chem 57: 6301-15 (2014) Article DOI: 10.1021/jm5000547 BindingDB Entry DOI: 10.7270/Q2NS0XW8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin beta-3 (Rattus norvegicus) | BDBM50004058 ((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to rat platelet integrin alpha2b beta3 by ELISA based solid phase binding assay | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01330 BindingDB Entry DOI: 10.7270/Q2G44V23 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Integrin beta-3 (Rattus norvegicus) | BDBM50004058 ((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to rat platelet integrin alpha2b beta3 by ELISA based solid phase binding assay | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01330 BindingDB Entry DOI: 10.7270/Q2G44V23 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Integrin beta-3 (Rattus norvegicus) | BDBM50568659 (CHEMBL4861415) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 603 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to rat platelet integrin alpha2b beta3 by ELISA based solid phase binding assay | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01330 BindingDB Entry DOI: 10.7270/Q2G44V23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin beta-3 (Rattus norvegicus) | BDBM50568659 (CHEMBL4861415) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to rat platelet integrin alpha2b beta3 by ELISA based solid phase binding assay | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01330 BindingDB Entry DOI: 10.7270/Q2G44V23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin beta-3 (Rattus norvegicus) | BDBM50568658 (CHEMBL4853717) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to rat platelet integrin alpha2b beta3 by ELISA based solid phase binding assay | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01330 BindingDB Entry DOI: 10.7270/Q2G44V23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin beta-3 (Rattus norvegicus) | BDBM50568658 (CHEMBL4853717) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 897 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of fibrinogen binding to rat platelet integrin alpha2b beta3 by ELISA based solid phase binding assay | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c01330 BindingDB Entry DOI: 10.7270/Q2G44V23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin beta-3/subunit alpha 2b (Rattus norvegicus) | BDBM50453875 (CHEMBL1811964) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a |
Capital Medical University Curated by ChEMBL | Assay Description Binding affinity to GP2b/3a in rat blood assessed as conformational change by measuring soluble GP2b/3a levels after 12 hrs by UV-spectrophotometric ... | Bioorg Med Chem Lett 27: 5114-5118 (2017) Article DOI: 10.1016/j.bmcl.2017.10.068 BindingDB Entry DOI: 10.7270/Q2445Q2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin beta-3 (Rattus norvegicus) | BDBM50453876 (CHEMBL4212580) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a |
Capital Medical University Curated by ChEMBL | Assay Description Binding affinity to GP2b/3a in rat blood assessed as conformational change by measuring soluble GP2b/3a levels after 12 hrs by UV-spectrophotometric ... | Bioorg Med Chem Lett 27: 5114-5118 (2017) Article DOI: 10.1016/j.bmcl.2017.10.068 BindingDB Entry DOI: 10.7270/Q2445Q2Q | |||||||||||
More data for this Ligand-Target Pair |