Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65870 ((4-Methoxy-benzyl)-naphthalen-1-ylmethyl-amine | 1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of mouse Kir2.1 expressed in HEK293 cells by patch clamp technique | J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM328993 (5-[[4-[[(2R)-morpholin-2-yl]methylamino]-5-(triflu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human Kir2.1 | Citation and Details Article DOI: 10.1021/acs.jmedchem.5b01938 BindingDB Entry DOI: 10.7270/Q2MG7T5V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM600745 (US11632953, Compound 1 | US11632953, Compound VU04...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5S4F | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM600745 (US11632953, Compound 1 | US11632953, Compound VU04...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5S4F | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65858 (MLS000557943 | N-[2-[5-[(4-chlorobenzyl)thio]-1,3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65871 (5-bromanyl-N-(1-phenylethyl)thiophene-2-sulfonamid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 1.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65874 (2-[[2-[(2-hydroxy-5-methyl-benzyl)amino]ethylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65865 ((E)-N-[(4-methoxyphenyl)methyl]-3-phenyl-2-propen-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65861 (1-{[3-(3-phenoxyphenoxy)propyl]amino}-2-propanol e...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65872 (1-[(4-fluorobenzyl)amino]-3-(4-methylphenoxy)propa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65868 (4-Bromo-N-(1-phenyl-ethyl)-benzenesulfonamide | 4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 2.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65859 (2-Cyclopropyl-1-phenethyl-1H-benzoimidazole | 2-cy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65870 ((4-Methoxy-benzyl)-naphthalen-1-ylmethyl-amine | 1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50312125 (3-chloro-N-(3-(3-methylbenzamido)phenyl)benzamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) | Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM600754 (US11632953, Compound 12 | VU0652942) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5S4F | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM600751 (US11632953, Compound 9 | VU0652954) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5S4F | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM600748 (US11632953, Compound 5 | VU0650730) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5S4F | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM600747 (US11632953, Compound 4 | VU0650729) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5S4F | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50258216 (CHEMBL4105630) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States. Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) by patch clamp assay | J Med Chem 60: 7810-7819 (2017) Article DOI: 10.1021/acs.jmedchem.7b00846 BindingDB Entry DOI: 10.7270/Q2ZK5K4W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50050539 (CHEMBL3187891) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) | Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50050534 (CHEMBL3183773) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) | Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50050530 (CHEMBL3188857) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) | Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM600755 (US11632953, Compound 13 | VU0652943) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5S4F | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50312105 (2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) | Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65863 (3-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-1H-in...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 3.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM43753 (6-methyl-N-(phenylmethyl)-1H-benzimidazol-2-amine ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 3.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65857 (3-(4-benzoxyphenoxy)propyl-cyclopentyl-amine;oxali...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 3.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65855 ((4-methoxyphenyl)-(4-quinolyl)amine;hydrochloride ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PCBioAssay | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65873 ((3-bromo-4-methoxy-benzyl)-homopiperonyl-amine;oxa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 3.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65856 (3-chloranyl-4-(1-ethylbenzimidazol-2-yl)sulfanyl-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 3.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65862 (2-[(2,4-dichlorobenzylidene)amino]guanidine | 2-[(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 3.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65867 ((1-benzyl-4-piperidyl)-(4-chlorobenzyl)amine | 1-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 3.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65860 (4-(methylthio)-N-(1-phenylethyl)benzenesulfonamide...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65869 ((2,8-Dimethyl-quinolin-4-yl)-p-tolyl-amine | (2,8-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 4.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65854 (4-[[4-ethyl-5-(phenoxymethyl)-1,2,4-triazol-3-yl]s...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 4.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50442600 (CHEMBL2441437 | US9056859, 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Kir2.1 channel (unknown origin) | Bioorg Med Chem Lett 23: 5829-32 (2013) Article DOI: 10.1016/j.bmcl.2013.08.104 BindingDB Entry DOI: 10.7270/Q28K7BHG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM155928 (US9018211, 52) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Kir2.1 potassium channel (unknown origin) | ACS Med Chem Lett 6: 747-52 (2015) Article DOI: 10.1021/ml500440u BindingDB Entry DOI: 10.7270/Q27H1MCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM162872 (US9056859, 72) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) | Bioorg Med Chem Lett 26: 2339-43 (2016) Article DOI: 10.1016/j.bmcl.2016.03.035 BindingDB Entry DOI: 10.7270/Q2668G3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65864 (1-adamantyl-(1-propyl-4-piperidyl)amine | MLS00097...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 5.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Mus musculus) | BDBM65866 (1-(4-Fluoro-benzenesulfonyl)-1,2,3,4-tetrahydro-qu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 5.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay | Assay Description Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R98 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50249183 (CHEMBL4069245) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co. Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) | Bioorg Med Chem Lett 27: 2559-2566 (2017) Article DOI: 10.1016/j.bmcl.2017.03.086 BindingDB Entry DOI: 10.7270/Q2BV7K1G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50257064 (CHEMBL2386850) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Radiology and Radiological Sciences, Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center , Nashville, Tennessee 37232, United States. Curated by ChEMBL | Assay Description Inhibition of human Kir2.1 expressed in CHO cells by automated patch clamp assay | J Med Chem 60: 5072-5085 (2017) Article DOI: 10.1021/acs.jmedchem.7b00410 BindingDB Entry DOI: 10.7270/Q2JH3PM7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50204281 (CHEMBL3933749) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Kir2.1 (unknown origin) | Bioorg Med Chem Lett 26: 5695-5702 (2016) Article DOI: 10.1016/j.bmcl.2016.10.064 BindingDB Entry DOI: 10.7270/Q2F191PS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50391771 (CHEMBL2146754) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Kir2.1 expressed in HEK293 cells assessed as inhibition of thallium efflux by fluorescence assay | ACS Med Chem Lett 3: 367-372 (2012) Article DOI: 10.1021/ml3000066 BindingDB Entry DOI: 10.7270/Q2MK6DZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Inward rectifier potassium channel 2 (Homo sapiens (Human)) | BDBM50391770 (CHEMBL2146755 | US9073882, 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Kir2.1 expressed in HEK293 cells assessed as inhibition of thallium efflux by fluorescence assay | ACS Med Chem Lett 3: 367-372 (2012) Article DOI: 10.1021/ml3000066 BindingDB Entry DOI: 10.7270/Q2MK6DZV | |||||||||||
More data for this Ligand-Target Pair |