Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Deoxyribonuclease gamma (Homo sapiens (Human)) | BDBM50206432 (4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nis Curated by ChEMBL | Assay Description Inhibition of DNase gamma (unknown origin) transfected in HeLa S3 cells | Eur J Med Chem 88: 101-11 (2014) Article DOI: 10.1016/j.ejmech.2014.07.040 BindingDB Entry DOI: 10.7270/Q2M32XC3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Deoxyribonuclease gamma (Homo sapiens (Human)) | BDBM50206432 (4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description Inhibition of human recombinant DNase gamma expressed in Rosetta DE3 cells assessed as increase in acidsoluble DNA after 30 mins | Bioorg Med Chem 19: 168-71 (2011) Article DOI: 10.1016/j.bmc.2010.11.037 BindingDB Entry DOI: 10.7270/Q2PK0GDV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Deoxyribonuclease gamma (Homo sapiens (Human)) | BDBM50333185 (CHEMBL1644886 | Pontacyl Violet 6R) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description Inhibition of human recombinant DNase gamma expressed in Rosetta DE3 cells assessed as increase in acidsoluble DNA after 30 mins | Bioorg Med Chem 19: 168-71 (2011) Article DOI: 10.1016/j.bmc.2010.11.037 BindingDB Entry DOI: 10.7270/Q2PK0GDV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Deoxyribonuclease gamma (Homo sapiens (Human)) | BDBM50206432 (4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description Inhibition of DNase gamma-mediated HMGB1 release expressed in human staurosporine-induced HeLaS3 cells treated 1 hr before staurosporine challenge me... | Bioorg Med Chem 19: 168-71 (2011) Article DOI: 10.1016/j.bmc.2010.11.037 BindingDB Entry DOI: 10.7270/Q2PK0GDV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Deoxyribonuclease gamma (Homo sapiens (Human)) | BDBM50333186 ((R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Science Curated by ChEMBL | Assay Description Inhibition of human recombinant DNase gamma expressed in Rosetta DE3 cells assessed as increase in acidsoluble DNA after 30 mins | Bioorg Med Chem 19: 168-71 (2011) Article DOI: 10.1016/j.bmc.2010.11.037 BindingDB Entry DOI: 10.7270/Q2PK0GDV | |||||||||||
More data for this Ligand-Target Pair |