Found 167 hits Enz. Inhib. hit(s) with Target = 'Lysophosphatidic acid receptor 2' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271765
(3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phen...)Show SMILES OC(=O)\C=C\C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)\C=C\C(O)=O)cc3)c2)cc1 Show InChI InChI=1S/C26H20N2O8/c29-23(12-14-25(31)32)27-17-4-8-19(9-5-17)35-21-2-1-3-22(16-21)36-20-10-6-18(7-11-20)28-24(30)13-15-26(33)34/h1-16H,(H,27,29)(H,28,30)(H,31,32)(H,33,34)/b14-12+,15-13+ | NCI pathway
Reactome pathway
KEGG
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... |
Bioorg Med Chem 16: 6207-17 (2008)
Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271763
(3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-ac...)Show SMILES OC(=O)\C=C\C(=O)Nc1cccc(NC(=O)\C=C\C(O)=O)c1 Show InChI InChI=1S/C14H12N2O6/c17-11(4-6-13(19)20)15-9-2-1-3-10(8-9)16-12(18)5-7-14(21)22/h1-8H,(H,15,17)(H,16,18)(H,19,20)(H,21,22)/b6-4+,7-5+ | NCI pathway
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... |
Bioorg Med Chem 16: 6207-17 (2008)
Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271764
(3-[4'-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarba...)Show SMILES OC(=O)\C=C\C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)\C=C\C(O)=O)cc1 Show InChI InChI=1S/C20H16N2O6/c23-17(9-11-19(25)26)21-15-5-1-13(2-6-15)14-3-7-16(8-4-14)22-18(24)10-12-20(27)28/h1-12H,(H,21,23)(H,22,24)(H,25,26)(H,27,28)/b11-9+,12-10+ | NCI pathway
Reactome pathway
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CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 21.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... |
Bioorg Med Chem 16: 6207-17 (2008)
Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50177331
(CHEMBL381470 | potassium (2-dodecyl-1,3-dioxolan-4...)Show InChI InChI=1S/C16H33O6P/c1-2-3-4-5-6-7-8-9-10-11-12-16-20-13-15(22-16)14-21-23(17,18)19/h15-16H,2-14H2,1H3,(H2,17,18,19)/p-1 | NCI pathway
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 745 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description
Activity at LPA2 receptor in RH7777 rat hepatoma cell line |
Bioorg Med Chem Lett 16: 451-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.096
BindingDB Entry DOI: 10.7270/Q2Z89C01 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50177331
(CHEMBL381470 | potassium (2-dodecyl-1,3-dioxolan-4...)Show InChI InChI=1S/C16H33O6P/c1-2-3-4-5-6-7-8-9-10-11-12-16-20-13-15(22-16)14-21-23(17,18)19/h15-16H,2-14H2,1H3,(H2,17,18,19)/p-1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 745 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description
Activity at LPA2 receptor in RH7777 rat hepatoma cell line |
Bioorg Med Chem Lett 16: 451-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.096
BindingDB Entry DOI: 10.7270/Q2Z89C01 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50170846
(CHEMBL190999 | Tetradecyl-phosphonic acid)Show InChI InChI=1S/C14H31O3P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18(15,16)17/h2-14H2,1H3,(H2,15,16,17) | NCI pathway
Reactome pathway
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PC cid
PC sid
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| Article
PubMed
| 3.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description
Binding affinity for Lysophosphatidic acid receptor 2 expressed in RH7777 rat hepatoma cells |
J Med Chem 48: 4919-30 (2005)
Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148435
(CHEMBL119116 | [3-(3,5-Dichloro-4-octyloxy-benzyla...)Show InChI InChI=1S/C18H30Cl2NO4P/c1-2-3-4-5-6-7-10-25-18-16(19)12-15(13-17(18)20)14-21-9-8-11-26(22,23)24/h12-13,21H,2-11,14H2,1H3,(H2,22,23,24) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271765
(3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phen...)Show SMILES OC(=O)\C=C\C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)\C=C\C(O)=O)cc3)c2)cc1 Show InChI InChI=1S/C26H20N2O8/c29-23(12-14-25(31)32)27-17-4-8-19(9-5-17)35-21-2-1-3-22(16-21)36-20-10-6-18(7-11-20)28-24(30)13-15-26(33)34/h1-16H,(H,27,29)(H,28,30)(H,31,32)(H,33,34)/b14-12+,15-13+ | NCI pathway
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... |
Bioorg Med Chem 16: 6207-17 (2008)
Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271765
(3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phen...)Show SMILES OC(=O)\C=C\C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)\C=C\C(O)=O)cc3)c2)cc1 Show InChI InChI=1S/C26H20N2O8/c29-23(12-14-25(31)32)27-17-4-8-19(9-5-17)35-21-2-1-3-22(16-21)36-20-10-6-18(7-11-20)28-24(30)13-15-26(33)34/h1-16H,(H,27,29)(H,28,30)(H,31,32)(H,33,34)/b14-12+,15-13+ | NCI pathway
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium response |
Bioorg Med Chem 17: 7457-64 (2009)
Article DOI: 10.1016/j.bmc.2009.09.022
BindingDB Entry DOI: 10.7270/Q2GB244M |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens) | CHEMBL5278054
| Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens) | CHEMBL5290275
| Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens) | CHEMBL5283300
| Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens) | CHEMBL5282947
| Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens) | CHEMBL5266099
| Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148432
(CHEMBL119440 | [3-(3,5-Dimethyl-4-octyloxy-benzyla...)Show InChI InChI=1S/C20H36NO4P/c1-4-5-6-7-8-9-12-25-20-17(2)14-19(15-18(20)3)16-21-11-10-13-26(22,23)24/h14-15,21H,4-13,16H2,1-3H3,(H2,22,23,24) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50373826
(CHEMBL256470)Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(Cl)c1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C20H23Cl2N5O2S2/c1-13-11-30-19-18(13)23-12-24-20(19)25-14(2)10-26-5-7-27(8-6-26)31(28,29)15-3-4-16(21)17(22)9-15/h3-4,9,11-12,14H,5-8,10H2,1-2H3,(H,23,24,25)/t14-/m0/s1 | NCI pathway
Reactome pathway
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CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay |
Bioorg Med Chem Lett 18: 1037-41 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.024
BindingDB Entry DOI: 10.7270/Q2JQ11W8 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148427
(CHEMBL441826 | [3-(3-Bromo-4-decyloxy-5-methoxy-be...)Show InChI InChI=1S/C21H37BrNO5P/c1-3-4-5-6-7-8-9-10-13-28-21-19(22)15-18(16-20(21)27-2)17-23-12-11-14-29(24,25)26/h15-16,23H,3-14,17H2,1-2H3,(H2,24,25,26) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271763
(3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-ac...)Show SMILES OC(=O)\C=C\C(=O)Nc1cccc(NC(=O)\C=C\C(O)=O)c1 Show InChI InChI=1S/C14H12N2O6/c17-11(4-6-13(19)20)15-9-2-1-3-10(8-9)16-12(18)5-7-14(21)22/h1-8H,(H,15,17)(H,16,18)(H,19,20)(H,21,22)/b6-4+,7-5+ | NCI pathway
Reactome pathway
KEGG
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21.8 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... |
Bioorg Med Chem 16: 6207-17 (2008)
Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271763
(3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-ac...)Show SMILES OC(=O)\C=C\C(=O)Nc1cccc(NC(=O)\C=C\C(O)=O)c1 Show InChI InChI=1S/C14H12N2O6/c17-11(4-6-13(19)20)15-9-2-1-3-10(8-9)16-12(18)5-7-14(21)22/h1-8H,(H,15,17)(H,16,18)(H,19,20)(H,21,22)/b6-4+,7-5+ | NCI pathway
Reactome pathway
KEGG
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium response |
Bioorg Med Chem 17: 7457-64 (2009)
Article DOI: 10.1016/j.bmc.2009.09.022
BindingDB Entry DOI: 10.7270/Q2GB244M |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148414
(CHEMBL332667 | [3-(3,5-Dibromo-4-octyloxy-benzylam...)Show InChI InChI=1S/C18H30Br2NO4P/c1-2-3-4-5-6-7-10-25-18-16(19)12-15(13-17(18)20)14-21-9-8-11-26(22,23)24/h12-13,21H,2-11,14H2,1H3,(H2,22,23,24) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148418
(CHEMBL119256 | [3-(4-Octyl-benzylamino)-propyl]-ph...)Show InChI InChI=1S/C18H32NO3P/c1-2-3-4-5-6-7-9-17-10-12-18(13-11-17)16-19-14-8-15-23(20,21)22/h10-13,19H,2-9,14-16H2,1H3,(H2,20,21,22) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271764
(3-[4'-(3-Carboxy-acryloylamino)-biphenyl-4-ylcarba...)Show SMILES OC(=O)\C=C\C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)\C=C\C(O)=O)cc1 Show InChI InChI=1S/C20H16N2O6/c23-17(9-11-19(25)26)21-15-5-1-13(2-6-15)14-3-7-16(8-4-14)22-18(24)10-12-20(27)28/h1-12H,(H,21,23)(H,22,24)(H,25,26)(H,27,28)/b11-9+,12-10+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 28.3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... |
Bioorg Med Chem 16: 6207-17 (2008)
Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148430
(CHEMBL331054 | [3-(3-Methyl-4-octyloxy-benzylamino...)Show InChI InChI=1S/C19H34NO4P/c1-3-4-5-6-7-8-13-24-19-11-10-18(15-17(19)2)16-20-12-9-14-25(21,22)23/h10-11,15,20H,3-9,12-14,16H2,1-2H3,(H2,21,22,23) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148423
(CHEMBL118783 | [3-(3-Bromo-4-heptyloxy-5-methoxy-b...)Show InChI InChI=1S/C18H31BrNO5P/c1-3-4-5-6-7-10-25-18-16(19)12-15(13-17(18)24-2)14-20-9-8-11-26(21,22)23/h12-13,20H,3-11,14H2,1-2H3,(H2,21,22,23) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50373827
(CHEMBL270865)Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1cccc(Cl)c1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C20H24ClN5O2S2/c1-14-12-29-19-18(14)22-13-23-20(19)24-15(2)11-25-6-8-26(9-7-25)30(27,28)17-5-3-4-16(21)10-17/h3-5,10,12-13,15H,6-9,11H2,1-2H3,(H,22,23,24)/t15-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay |
Bioorg Med Chem Lett 18: 1037-41 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.024
BindingDB Entry DOI: 10.7270/Q2JQ11W8 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148438
(CHEMBL119354 | [3-(3-Bromo-4-octyloxy-benzylamino)...)Show InChI InChI=1S/C18H31BrNO4P/c1-2-3-4-5-6-7-12-24-18-10-9-16(14-17(18)19)15-20-11-8-13-25(21,22)23/h9-10,14,20H,2-8,11-13,15H2,1H3,(H2,21,22,23) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148394
(CHEMBL118860 | [3-(4-Nonyl-benzylamino)-propyl]-ph...)Show InChI InChI=1S/C19H34NO3P/c1-2-3-4-5-6-7-8-10-18-11-13-19(14-12-18)17-20-15-9-16-24(21,22)23/h11-14,20H,2-10,15-17H2,1H3,(H2,21,22,23) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148424
(CHEMBL118815 | [3-(3-Bromo-5-methoxy-4-undecyloxy-...)Show InChI InChI=1S/C22H39BrNO5P/c1-3-4-5-6-7-8-9-10-11-14-29-22-20(23)16-19(17-21(22)28-2)18-24-13-12-15-30(25,26)27/h16-17,24H,3-15,18H2,1-2H3,(H2,25,26,27) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148421
(CHEMBL119413 | [3-(3-Chloro-4-octyloxy-benzylamino...)Show InChI InChI=1S/C18H31ClNO4P/c1-2-3-4-5-6-7-12-24-18-10-9-16(14-17(18)19)15-20-11-8-13-25(21,22)23/h9-10,14,20H,2-8,11-13,15H2,1H3,(H2,21,22,23) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148420
(CHEMBL117715 | [3-(3-Chloro-5-methoxy-4-octyloxy-b...)Show InChI InChI=1S/C19H33ClNO5P/c1-3-4-5-6-7-8-11-26-19-17(20)13-16(14-18(19)25-2)15-21-10-9-12-27(22,23)24/h13-14,21H,3-12,15H2,1-2H3,(H2,22,23,24) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148425
(CHEMBL119873 | [3-(3-Fluoro-4-octyloxy-benzylamino...)Show InChI InChI=1S/C18H31FNO4P/c1-2-3-4-5-6-7-12-24-18-10-9-16(14-17(18)19)15-20-11-8-13-25(21,22)23/h9-10,14,20H,2-8,11-13,15H2,1H3,(H2,21,22,23) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148433
(CHEMBL333335 | [3-(4-Nonyloxy-benzylamino)-propyl]...)Show InChI InChI=1S/C19H34NO4P/c1-2-3-4-5-6-7-8-15-24-19-12-10-18(11-13-19)17-20-14-9-16-25(21,22)23/h10-13,20H,2-9,14-17H2,1H3,(H2,21,22,23) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148439
(3-(3-bromo-5-methoxy-4-(octyloxy)benzylamino)propy...)Show InChI InChI=1S/C19H33BrNO5P/c1-3-4-5-6-7-8-11-26-19-17(20)13-16(14-18(19)25-2)15-21-10-9-12-27(22,23)24/h13-14,21H,3-12,15H2,1-2H3,(H2,22,23,24) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148419
(CHEMBL432813 | [3-(3-Methoxy-5-methyl-4-octyloxy-b...)Show InChI InChI=1S/C20H36NO5P/c1-4-5-6-7-8-9-12-26-20-17(2)14-18(15-19(20)25-3)16-21-11-10-13-27(22,23)24/h14-15,21H,4-13,16H2,1-3H3,(H2,22,23,24) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148426
(CHEMBL323617 | {3-[4-(5-Heptyl-[1,2,4]oxadiazol-3-...)Show InChI InChI=1S/C19H30N3O4P/c1-2-3-4-5-6-8-18-21-19(22-26-18)17-11-9-16(10-12-17)15-20-13-7-14-27(23,24)25/h9-12,20H,2-8,13-15H2,1H3,(H2,23,24,25) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148413
(CHEMBL116981 | {3-[(4'-Hexyl-biphenyl-4-ylmethyl)-...)Show InChI InChI=1S/C22H32NO3P/c1-2-3-4-5-7-19-8-12-21(13-9-19)22-14-10-20(11-15-22)18-23-16-6-17-27(24,25)26/h8-15,23H,2-7,16-18H2,1H3,(H2,24,25,26) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50373815
(CHEMBL401756)Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C21H27N5O2S2/c1-15-4-6-18(7-5-15)30(27,28)26-10-8-25(9-11-26)12-17(3)24-21-20-19(22-14-23-21)16(2)13-29-20/h4-7,13-14,17H,8-12H2,1-3H3,(H,22,23,24)/t17-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay |
Bioorg Med Chem Lett 18: 1037-41 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.024
BindingDB Entry DOI: 10.7270/Q2JQ11W8 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148416
(CHEMBL115970 | [3-(4-Nonanoyl-benzylamino)-propyl]...)Show InChI InChI=1S/C19H32NO4P/c1-2-3-4-5-6-7-9-19(21)18-12-10-17(11-13-18)16-20-14-8-15-25(22,23)24/h10-13,20H,2-9,14-16H2,1H3,(H2,22,23,24) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50373817
(CHEMBL404452)Show SMILES C[C@@H](CN1CCN(CC1)c1ccccc1C)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C21H27N5S/c1-15-6-4-5-7-18(15)26-10-8-25(9-11-26)12-17(3)24-21-20-19(22-14-23-21)16(2)13-27-20/h4-7,13-14,17H,8-12H2,1-3H3,(H,22,23,24)/t17-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay |
Bioorg Med Chem Lett 18: 1037-41 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.024
BindingDB Entry DOI: 10.7270/Q2JQ11W8 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148428
(CHEMBL325247 | [3-(3-Bromo-4-hexyloxy-5-methoxy-be...)Show InChI InChI=1S/C17H29BrNO5P/c1-3-4-5-6-9-24-17-15(18)11-14(12-16(17)23-2)13-19-8-7-10-25(20,21)22/h11-12,19H,3-10,13H2,1-2H3,(H2,20,21,22) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148436
(CHEMBL119382 | {3-[4-(2-Heptyl-2H-tetrazol-5-yl)-b...)Show InChI InChI=1S/C18H30N5O3P/c1-2-3-4-5-6-13-23-21-18(20-22-23)17-10-8-16(9-11-17)15-19-12-7-14-27(24,25)26/h8-11,19H,2-7,12-15H2,1H3,(H2,24,25,26) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50373828
(CHEMBL427893)Show SMILES C[C@@H](CN1CCN(CC1)S(=O)(=O)c1cccc(C)c1)Nc1ncnc2c(C)csc12 Show InChI InChI=1S/C21H27N5O2S2/c1-15-5-4-6-18(11-15)30(27,28)26-9-7-25(8-10-26)12-17(3)24-21-20-19(22-14-23-21)16(2)13-29-20/h4-6,11,13-14,17H,7-10,12H2,1-3H3,(H,22,23,24)/t17-/m0/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay |
Bioorg Med Chem Lett 18: 1037-41 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.024
BindingDB Entry DOI: 10.7270/Q2JQ11W8 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271701
(2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2...)Show SMILES OC(=O)\C=C\C(=O)Nc1cccc(NC(=O)\C=C\C(O)=O)c1C(O)=O Show InChI InChI=1S/C15H12N2O8/c18-10(4-6-12(20)21)16-8-2-1-3-9(14(8)15(24)25)17-11(19)5-7-13(22)23/h1-7H,(H,16,18)(H,17,19)(H,20,21)(H,22,23)(H,24,25)/b6-4+,7-5+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce... |
Bioorg Med Chem 16: 6207-17 (2008)
Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50271701
(2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2...)Show SMILES OC(=O)\C=C\C(=O)Nc1cccc(NC(=O)\C=C\C(O)=O)c1C(O)=O Show InChI InChI=1S/C15H12N2O8/c18-10(4-6-12(20)21)16-8-2-1-3-9(14(8)15(24)25)17-11(19)5-7-13(22)23/h1-7H,(H,16,18)(H,17,19)(H,20,21)(H,22,23)(H,24,25)/b6-4+,7-5+ | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Memphis
Curated by ChEMBL
| Assay Description
Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium response |
Bioorg Med Chem 17: 7457-64 (2009)
Article DOI: 10.1016/j.bmc.2009.09.022
BindingDB Entry DOI: 10.7270/Q2GB244M |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148431
(CHEMBL324820 | [3-(3-Ethoxy-4-octyloxy-benzylamino...)Show InChI InChI=1S/C20H36NO5P/c1-3-5-6-7-8-9-14-26-19-12-11-18(16-20(19)25-4-2)17-21-13-10-15-27(22,23)24/h11-12,16,21H,3-10,13-15,17H2,1-2H3,(H2,22,23,24) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148429
(CHEMBL118508 | [3-(3-Methoxy-4-octyloxy-benzylamin...)Show InChI InChI=1S/C19H34NO5P/c1-3-4-5-6-7-8-13-25-18-11-10-17(15-19(18)24-2)16-20-12-9-14-26(21,22)23/h10-11,15,20H,3-9,12-14,16H2,1-2H3,(H2,21,22,23) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens) | CHEMBL5288868
| Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | <500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens) | CHEMBL5269328
| Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | <500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens) | CHEMBL5279488
| Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | <500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50148437
(CHEMBL332373 | [3-(4-Octyloxy-benzylamino)-propyl]...)Show InChI InChI=1S/C18H32NO4P/c1-2-3-4-5-6-7-14-23-18-11-9-17(10-12-18)16-19-13-8-15-24(20,21)22/h9-12,19H,2-8,13-16H2,1H3,(H2,20,21,22) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligand |
Bioorg Med Chem Lett 14: 3501-5 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.070
BindingDB Entry DOI: 10.7270/Q2W66K76 |
More data for this
Ligand-Target Pair | |
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