Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50237710 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by PDSP Ki Database | Proc Natl Acad Sci U S A 103: 3153-8 (2006) Article DOI: 10.1073/pnas.0511292103 BindingDB Entry DOI: 10.7270/Q21Z430B | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481131 (US10906896, Cpd 8300 | US10906896, Cpd 832 | US117...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481115 (US10906896, Cpd 119) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Qilu Pharmaceutical Co, Ltd Curated by ChEMBL | Assay Description Binding affinity to c-KIT (unknown origin) | Eur J Med Chem 82: 139-51 (2014) Article DOI: 10.1016/j.ejmech.2014.05.051 BindingDB Entry DOI: 10.7270/Q2F1918D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481138 (US10906896, Cpd 8200 | US11725005, Compound 8200) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481143 (US10906896, Cpd 8270 | US11725005, Compound 8270) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481131 (US10906896, Cpd 8300 | US10906896, Cpd 832 | US117...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481145 (US10906896, Cpd 8290 | US11725005, Compound 8290) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481113 (US10906896, Cpd 117) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481125 (US10906896, Cpd 404) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481126 (US10906896, Cpd 405) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481130 (US10906896, Cpd 830 | US11725005, Compound 830) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481144 (US10906896, Cpd 8280 | US11725005, Compound 8280) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481105 (US10906896, Cpd 102) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481104 (US10906896, Cpd 101) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481107 (US10906896, Cpd 107) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481108 (US10906896, Cpd 108) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481109 (US10906896, Cpd 113) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481106 (US10906896, Cpd 103) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481128 (US10906896, Cpd 809 | US11725005, Compound 809) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481114 (US10906896, Cpd 118) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481111 (US10906896, Cpd 115) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50355464 (CHEMBL1835740) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation counting | J Med Chem 54: 7184-92 (2011) Article DOI: 10.1021/jm200712h BindingDB Entry DOI: 10.7270/Q2DZ08QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481121 (US10906896, Cpd 305) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481137 (US10906896, Cpd 8190 | US11725005, Compound 8190) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50355486 (CHEMBL1835864) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation counting | J Med Chem 54: 7184-92 (2011) Article DOI: 10.1021/jm200712h BindingDB Entry DOI: 10.7270/Q2DZ08QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50388875 (CHEMBL2062935) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of KIT | ACS Med Chem Lett 3: 383-386 (2012) Article DOI: 10.1021/ml300012r BindingDB Entry DOI: 10.7270/Q2B56KTH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50341530 (3-(4-(Piperidin-1-yl)benzoylamino)-5-(2-(methylami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL | Assay Description Inhibition of c-Kit after 45 mins by radiometric phosphate incorporation assay | J Med Chem 54: 2341-50 (2011) Article DOI: 10.1021/jm101499u BindingDB Entry DOI: 10.7270/Q2KH0NPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481129 (US10906896, Cpd 820 | US11725005, Compound 820) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481135 (BDBM481139 | US10906896, Cpd 8170 | US11725005, Co...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481124 (US10906896, Cpd 402) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 11.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481112 (US10906896, Cpd 116) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 11.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50341520 (3-(4-(Piperidin-1-yl)benzoylamino)-5-(pyridin-4-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL | Assay Description Inhibition of KIT | J Med Chem 54: 2341-50 (2011) Article DOI: 10.1021/jm101499u BindingDB Entry DOI: 10.7270/Q2KH0NPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50341521 (3-(4-(Piperidin-1-yl)benzoylamino)-5-(2-(methylami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL | Assay Description Inhibition of KIT | J Med Chem 54: 2341-50 (2011) Article DOI: 10.1021/jm101499u BindingDB Entry DOI: 10.7270/Q2KH0NPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481132 (US10906896, Cpd 880 | US11725005, Compound 880) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50355465 (CHEMBL1835741) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation counting | J Med Chem 54: 7184-92 (2011) Article DOI: 10.1021/jm200712h BindingDB Entry DOI: 10.7270/Q2DZ08QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481119 (US10906896, Cpd 207) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 12.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481123 (US10906896, Cpd 401) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 12.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481136 (US10906896, Cpd 8180 | US11725005, Compound 8180) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481127 (US10906896, Cpd 806 | US11725005, Compound 806) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481122 (US10906896, Cpd 309) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genomics Institute of the Novartis Research Foundation Curated by PDSP Ki Database | Proc Natl Acad Sci U S A 103: 3153-8 (2006) Article DOI: 10.1073/pnas.0511292103 BindingDB Entry DOI: 10.7270/Q21Z430B | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481141 (US10906896, Cpd 8250 | US11725005, Compound 8250) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481142 (US10906896, Cpd 8260 | US11725005, Compound 8260) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50355480 (CHEMBL1835747) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation counting | J Med Chem 54: 7184-92 (2011) Article DOI: 10.1021/jm200712h BindingDB Entry DOI: 10.7270/Q2DZ08QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481120 (US10906896, Cpd 303) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 18.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481116 (US10906896, Cpd 201) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 19.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50355485 (CHEMBL1835863) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation counting | J Med Chem 54: 7184-92 (2011) Article DOI: 10.1021/jm200712h BindingDB Entry DOI: 10.7270/Q2DZ08QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50341540 (3-(4-tert-Butylbenzoylamino)-5-(pyridin-4-yl)-(1H)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL | Assay Description Inhibition of KIT | J Med Chem 54: 2341-50 (2011) Article DOI: 10.1021/jm101499u BindingDB Entry DOI: 10.7270/Q2KH0NPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM481133 (US10906896, Cpd 8120 | US11725005, Compound 8120) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Inhibikase Therapeutics, Inc. US Patent | Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re... | US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ | |||||||||||
More data for this Ligand-Target Pair |
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