BindingDB PrimarySearch

Found 19 hits Enz. Inhib. hit(s) with Target = 'Metacaspase-2'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metacaspase-2 (Trypanosoma brucei)	BDBM50313771 ((S)-benzyl 1-(benzo[d]thiazol-2-yl)-5-guanidino-1-...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313778 (CHEMBL1082043 \| benzyl 1-((S)-1-(benzo[d]thiazol-2...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313777 (CHEMBL1082042 \| benzyl 1-((S)-1-(benzo[d]thiazol-2...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM14297 (US10676470, Compound 23 \| US11332464, Compound 23 ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313779 ((S)-benzyl 1-cyano-4-guanidinobutylcarbamate \| CHE...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313773 ((S)-benzyl 5-guanidino-1-oxo-1-(thiazol-2-yl)penta...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313775 ((S)-benzyl 6-guanidino-1-(phenylsulfonyl)hex-1-en-...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313776 ((S)-benzyl 1-(benzo[d]thiazol-2-yl)-6-guanidino-1-...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313774 ((S)-benzyl 5-guanidino-1-(1-methyl-1H-benzo[d]imid...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313772 ((S)-benzyl 5-guanidino-1-oxo-1-(pyridin-2-yl)penta...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313781 ((S)-benzyl 1-cyano-2-(4-guanidinophenyl)ethylcarba...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313780 ((S)-benzyl 2-(4-aminophenyl)-1-cyanoethylcarbamate...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313770 (CHEMBL1081308 \| benzyl 4-(4-(bis(4-fluorophenyl)me...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313769 (CHEMBL1094051 \| benzyl cyanomethyl(4-(4-(4-fluorop...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313768 (CHEMBL1091473 \| benzyl cyanomethyl(4-(piperidin-1-...) Show SMILES O=C(OCc1ccccc1)N(CCCCN1CCCCC1)CC#N Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313767 (CHEMBL1091472 \| benzyl 4-(1H-imidazol-1-yl)butyl(c...) Show SMILES O=C(OCc1ccccc1)N(CCCCn1ccnc1)CC#N Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313782 (CHEMBL1089377 \| benzyl cyanomethyl(piperidin-4-yl)...) Show SMILES O=C(OCc1ccccc1)N(CC#N)C1CCNCC1 Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313765 (CHEMBL1091088 \| benzyl cyanomethyl(4-hydroxybutyl)...) Show SMILES OCCCCN(CC#N)C(=O)OCc1ccccc1 Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Metacaspase-2 (Trypanosoma brucei)	BDBM50313766 (CHEMBL1091471 \| benzyl cyanomethyl(4-(pyrrolidin-1...) Show SMILES O=C(OCc1ccccc1)N(CCCCN1CCCC1)CC#N Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei MAC2				Bioorg Med Chem Lett 20: 2001-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.099 BindingDB Entry DOI: 10.7270/Q2BG2P5T
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair