Found 884 hits Enz. Inhib. hit(s) with Target = 'Monocarboxylate transporter 4' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Monocarboxylate transporter 4
(Homo sapiens (Human)) | MSC-4381
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| UniChem
| | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5276884
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5279064
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5267752
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5281492
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5267349
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5287351
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5287780
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5268966
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5288904
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5265956
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5266104
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | CHEMBL5271816
| Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 222 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Mus musculus) | CHEMBL5282978
| MMDB
NCI pathway
Reactome pathway
KEGG
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | 301 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BINDARIT
(AF 2838 | AF-2838 | Bindarit) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | 3.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356917
(US10214492, Example 268 | US11292767, Example 268)Show SMILES CCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1-c1ccccc1N1CCCC1 |r| Show InChI InChI=1S/C28H33N5O3/c1-4-28(3,27(34)35)36-19-22-17-26(20-12-13-21-18-29-32(5-2)25(21)16-20)33(30-22)24-11-7-6-10-23(24)31-14-8-9-15-31/h6-7,10-13,16-18H,4-5,8-9,14-15,19H2,1-3H3,(H,34,35)/t28-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356917
(US10214492, Example 268 | US11292767, Example 268)Show SMILES CCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1-c1ccccc1N1CCCC1 |r| Show InChI InChI=1S/C28H33N5O3/c1-4-28(3,27(34)35)36-19-22-17-26(20-12-13-21-18-29-32(5-2)25(21)16-20)33(30-22)24-11-7-6-10-23(24)31-14-8-9-15-31/h6-7,10-13,16-18H,4-5,8-9,14-15,19H2,1-3H3,(H,34,35)/t28-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356917
(US10214492, Example 268 | US11292767, Example 268)Show SMILES CCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1-c1ccccc1N1CCCC1 |r| Show InChI InChI=1S/C28H33N5O3/c1-4-28(3,27(34)35)36-19-22-17-26(20-12-13-21-18-29-32(5-2)25(21)16-20)33(30-22)24-11-7-6-10-23(24)31-14-8-9-15-31/h6-7,10-13,16-18H,4-5,8-9,14-15,19H2,1-3H3,(H,34,35)/t28-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356873
(US10214492, Example 223 | US11292767, Example 223)Show SMILES CC[C@@](C)(OCc1cc(-c2cccc(OCC(C)(C)C)c2)n(n1)-c1cccc2cnn(C)c12)C(O)=O |r| Show InChI InChI=1S/C28H34N4O4/c1-7-28(5,26(33)34)36-17-21-15-24(19-10-8-12-22(14-19)35-18-27(2,3)4)32(30-21)23-13-9-11-20-16-29-31(6)25(20)23/h8-16H,7,17-18H2,1-6H3,(H,33,34)/t28-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356873
(US10214492, Example 223 | US11292767, Example 223)Show SMILES CC[C@@](C)(OCc1cc(-c2cccc(OCC(C)(C)C)c2)n(n1)-c1cccc2cnn(C)c12)C(O)=O |r| Show InChI InChI=1S/C28H34N4O4/c1-7-28(5,26(33)34)36-17-21-15-24(19-10-8-12-22(14-19)35-18-27(2,3)4)32(30-21)23-13-9-11-20-16-29-31(6)25(20)23/h8-16H,7,17-18H2,1-6H3,(H,33,34)/t28-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356790
(US10214492, Example 155 | US11292767, Example 155)Show SMILES CC(C)(C)COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1-c1ccccc1N1CCC1 Show InChI InChI=1S/C28H35N3O4/c1-27(2,3)19-34-22-11-8-10-20(16-22)25-17-21(18-35-28(4,5)26(32)33)29-31(25)24-13-7-6-12-23(24)30-14-9-15-30/h6-8,10-13,16-17H,9,14-15,18-19H2,1-5H3,(H,32,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356790
(US10214492, Example 155 | US11292767, Example 155)Show SMILES CC(C)(C)COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1-c1ccccc1N1CCC1 Show InChI InChI=1S/C28H35N3O4/c1-27(2,3)19-34-22-11-8-10-20(16-22)25-17-21(18-35-28(4,5)26(32)33)29-31(25)24-13-7-6-12-23(24)30-14-9-15-30/h6-8,10-13,16-17H,9,14-15,18-19H2,1-5H3,(H,32,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356906
(US10214492, Example 257 | US11292767, Example 257)Show SMILES CCn1ncc2ccc(cc12)-c1cc(CO[C@@](C)(CC)C(O)=O)nn1Cc1ccccc1Cl |r| Show InChI InChI=1S/C25H27ClN4O3/c1-4-25(3,24(31)32)33-16-20-13-23(30(28-20)15-19-8-6-7-9-21(19)26)17-10-11-18-14-27-29(5-2)22(18)12-17/h6-14H,4-5,15-16H2,1-3H3,(H,31,32)/t25-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356913
(US10214492, Example 264)Show SMILES CCOc1ccccc1Cn1nc(cc1-c1cc(OC)cc(OC)c1)[C@](C)(CC)OC(C)(C)C(O)=O |r| Show InChI InChI=1S/C28H36N2O6/c1-8-28(5,36-27(3,4)26(31)32)25-17-23(20-14-21(33-6)16-22(15-20)34-7)30(29-25)18-19-12-10-11-13-24(19)35-9-2/h10-17H,8-9,18H2,1-7H3,(H,31,32)/t28-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM546758
((2R)-2-([5-(3,5-Dimethoxyphenyl)-1- [(2-ethoxyphen...)Show SMILES CCOc1ccccc1Cn1nc(cc1-c1cc(OC)cc(OC)c1)[C@](C)(CC)OCC(O)=O |r| | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356906
(US10214492, Example 257 | US11292767, Example 257)Show SMILES CCn1ncc2ccc(cc12)-c1cc(CO[C@@](C)(CC)C(O)=O)nn1Cc1ccccc1Cl |r| Show InChI InChI=1S/C25H27ClN4O3/c1-4-25(3,24(31)32)33-16-20-13-23(30(28-20)15-19-8-6-7-9-21(19)26)17-10-11-18-14-27-29(5-2)22(18)12-17/h6-14H,4-5,15-16H2,1-3H3,(H,31,32)/t25-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356915
(US10214492, Example 266 | US11292767, Example 266)Show SMILES CC[C@@](C)(OCc1cc(-c2cccc(OC3CC3)c2)n(n1)-c1ccccc1N1CCC1)C(O)=O |r| Show InChI InChI=1S/C27H31N3O4/c1-3-27(2,26(31)32)33-18-20-17-25(19-8-6-9-22(16-19)34-21-12-13-21)30(28-20)24-11-5-4-10-23(24)29-14-7-15-29/h4-6,8-11,16-17,21H,3,7,12-15,18H2,1-2H3,(H,31,32)/t27-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356915
(US10214492, Example 266 | US11292767, Example 266)Show SMILES CC[C@@](C)(OCc1cc(-c2cccc(OC3CC3)c2)n(n1)-c1ccccc1N1CCC1)C(O)=O |r| Show InChI InChI=1S/C27H31N3O4/c1-3-27(2,26(31)32)33-18-20-17-25(19-8-6-9-22(16-19)34-21-12-13-21)30(28-20)24-11-5-4-10-23(24)29-14-7-15-29/h4-6,8-11,16-17,21H,3,7,12-15,18H2,1-2H3,(H,31,32)/t27-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356915
(US10214492, Example 266 | US11292767, Example 266)Show SMILES CC[C@@](C)(OCc1cc(-c2cccc(OC3CC3)c2)n(n1)-c1ccccc1N1CCC1)C(O)=O |r| Show InChI InChI=1S/C27H31N3O4/c1-3-27(2,26(31)32)33-18-20-17-25(19-8-6-9-22(16-19)34-21-12-13-21)30(28-20)24-11-5-4-10-23(24)29-14-7-15-29/h4-6,8-11,16-17,21H,3,7,12-15,18H2,1-2H3,(H,31,32)/t27-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356870
(US10214492, Example 220 | US11292767, Example 220)Show SMILES CCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1Cc1ccccc1Cl |r| Show InChI InChI=1S/C25H27ClN4O3/c1-4-25(3,24(31)32)33-16-20-13-23(30(28-20)15-19-8-6-7-9-21(19)26)17-10-11-18-14-27-29(5-2)22(18)12-17/h6-14H,4-5,15-16H2,1-3H3,(H,31,32)/t25-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356870
(US10214492, Example 220 | US11292767, Example 220)Show SMILES CCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1Cc1ccccc1Cl |r| Show InChI InChI=1S/C25H27ClN4O3/c1-4-25(3,24(31)32)33-16-20-13-23(30(28-20)15-19-8-6-7-9-21(19)26)17-10-11-18-14-27-29(5-2)22(18)12-17/h6-14H,4-5,15-16H2,1-3H3,(H,31,32)/t25-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356916
(US10214492, Example 267 | US11292767, Example 267)Show SMILES CCCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1-c1ccccc1N1CCC1 |r| Show InChI InChI=1S/C28H33N5O3/c1-4-13-32-25-16-20(11-12-21(25)18-29-32)26-17-22(19-36-28(3,5-2)27(34)35)30-33(26)24-10-7-6-9-23(24)31-14-8-15-31/h6-7,9-12,16-18H,4-5,8,13-15,19H2,1-3H3,(H,34,35)/t28-/m1/s1 | Reactome pathway
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UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356916
(US10214492, Example 267 | US11292767, Example 267)Show SMILES CCCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1-c1ccccc1N1CCC1 |r| Show InChI InChI=1S/C28H33N5O3/c1-4-13-32-25-16-20(11-12-21(25)18-29-32)26-17-22(19-36-28(3,5-2)27(34)35)30-33(26)24-10-7-6-9-23(24)31-14-8-15-31/h6-7,9-12,16-18H,4-5,8,13-15,19H2,1-3H3,(H,34,35)/t28-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
| | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356916
(US10214492, Example 267 | US11292767, Example 267)Show SMILES CCCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1-c1ccccc1N1CCC1 |r| Show InChI InChI=1S/C28H33N5O3/c1-4-13-32-25-16-20(11-12-21(25)18-29-32)26-17-22(19-36-28(3,5-2)27(34)35)30-33(26)24-10-7-6-9-23(24)31-14-8-15-31/h6-7,9-12,16-18H,4-5,8,13-15,19H2,1-3H3,(H,34,35)/t28-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356811
(US10214492, Example 172 | US11292767, Example 172)Show SMILES CCn1ncc2cccc(-n3nc(COC(C)(C)C(O)=O)cc3-c3cccc(OCC(C)(C)C)c3)c12 Show InChI InChI=1S/C28H34N4O4/c1-7-31-25-20(16-29-31)11-9-13-23(25)32-24(15-21(30-32)17-36-28(5,6)26(33)34)19-10-8-12-22(14-19)35-18-27(2,3)4/h8-16H,7,17-18H2,1-6H3,(H,33,34) | Reactome pathway
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356805
(US10214492, Example 167 | US11292767, Example 167)Show SMILES Cn1ncc2cccc(-n3nc(COC(C)(C)C(O)=O)cc3-c3cccc(OCC(C)(C)C)c3)c12 Show InChI InChI=1S/C27H32N4O4/c1-26(2,3)17-34-21-11-7-9-18(13-21)23-14-20(16-35-27(4,5)25(32)33)29-31(23)22-12-8-10-19-15-28-30(6)24(19)22/h7-15H,16-17H2,1-6H3,(H,32,33) | Reactome pathway
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UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356805
(US10214492, Example 167 | US11292767, Example 167)Show SMILES Cn1ncc2cccc(-n3nc(COC(C)(C)C(O)=O)cc3-c3cccc(OCC(C)(C)C)c3)c12 Show InChI InChI=1S/C27H32N4O4/c1-26(2,3)17-34-21-11-7-9-18(13-21)23-14-20(16-35-27(4,5)25(32)33)29-31(23)22-12-8-10-19-15-28-30(6)24(19)22/h7-15H,16-17H2,1-6H3,(H,32,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356811
(US10214492, Example 172 | US11292767, Example 172)Show SMILES CCn1ncc2cccc(-n3nc(COC(C)(C)C(O)=O)cc3-c3cccc(OCC(C)(C)C)c3)c12 Show InChI InChI=1S/C28H34N4O4/c1-7-31-25-20(16-29-31)11-9-13-23(25)32-24(15-21(30-32)17-36-28(5,6)26(33)34)19-10-8-12-22(14-19)35-18-27(2,3)4/h8-16H,7,17-18H2,1-6H3,(H,33,34) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356909
(US10214492, Example 260 | US11292767, Example 260)Show SMILES CC(C)(OCc1cc(-c2cccc(OC3CCC3)c2)n(n1)-c1ccccc1N1CCC1)C(O)=O Show InChI InChI=1S/C27H31N3O4/c1-27(2,26(31)32)33-18-20-17-25(19-8-5-11-22(16-19)34-21-9-6-10-21)30(28-20)24-13-4-3-12-23(24)29-14-7-15-29/h3-5,8,11-13,16-17,21H,6-7,9-10,14-15,18H2,1-2H3,(H,31,32) | Reactome pathway
KEGG
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.830 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356909
(US10214492, Example 260 | US11292767, Example 260)Show SMILES CC(C)(OCc1cc(-c2cccc(OC3CCC3)c2)n(n1)-c1ccccc1N1CCC1)C(O)=O Show InChI InChI=1S/C27H31N3O4/c1-27(2,26(31)32)33-18-20-17-25(19-8-5-11-22(16-19)34-21-9-6-10-21)30(28-20)24-13-4-3-12-23(24)29-14-7-15-29/h3-5,8,11-13,16-17,21H,6-7,9-10,14-15,18H2,1-2H3,(H,31,32) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.830 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345281
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)Show SMILES CC(C)COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C25H29ClN2O4/c1-17(2)15-31-21-10-7-9-18(12-21)23-13-20(16-32-25(3,4)24(29)30)27-28(23)14-19-8-5-6-11-22(19)26/h5-13,17H,14-16H2,1-4H3,(H,29,30) | Reactome pathway
KEGG
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| PC cid
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| | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2CR5ZGC |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50606665
(Isotense | Londomin | NSC-77030 | Neoreserpan | SU...)Show SMILES [H][C@]12C[C@@H](OC(=O)c3cc(OC)c(OC(=O)OCC)c(OC)c3)[C@H](OC)[C@@H](C(=O)OC)[C@@]1([H])C[C@@]1([H])N(CCc3c1[nH]c1cc(OC)ccc31)C2 | Reactome pathway
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113806
BindingDB Entry DOI: 10.7270/Q2M61QBT |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356918
(US10214492, Example 269 | US11292767, Example 269)Show SMILES CCn1ncc2ccc(cc12)-c1cc(CO[C@](C)(CC)C(O)=O)nn1-c1ccccc1N1CCC1 |r| Show InChI InChI=1S/C27H31N5O3/c1-4-27(3,26(33)34)35-18-21-16-25(19-11-12-20-17-28-31(5-2)24(20)15-19)32(29-21)23-10-7-6-9-22(23)30-13-8-14-30/h6-7,9-12,15-17H,4-5,8,13-14,18H2,1-3H3,(H,33,34)/t27-/m1/s1 | Reactome pathway
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| PC cid
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| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50606664
(CHEMBL1616099) | Reactome pathway
KEGG
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113806
BindingDB Entry DOI: 10.7270/Q2M61QBT |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345281
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)Show SMILES CC(C)COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C25H29ClN2O4/c1-17(2)15-31-21-10-7-9-18(12-21)23-13-20(16-32-25(3,4)24(29)30)27-28(23)14-19-8-5-6-11-22(19)26/h5-13,17H,14-16H2,1-4H3,(H,29,30) | Reactome pathway
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| PC cid
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| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50606663
(CHEMBL5219543)Show SMILES CC(C)(OCc1cc(-c2ccccc2)n(Cc2ccccc2)n1)C(O)=O | Reactome pathway
KEGG
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113806
BindingDB Entry DOI: 10.7270/Q2M61QBT |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345281
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)Show SMILES CC(C)COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C25H29ClN2O4/c1-17(2)15-31-21-10-7-9-18(12-21)23-13-20(16-32-25(3,4)24(29)30)27-28(23)14-19-8-5-6-11-22(19)26/h5-13,17H,14-16H2,1-4H3,(H,29,30) | Reactome pathway
KEGG
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PC sid
UniChem
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50606663
(CHEMBL5219543)Show SMILES CC(C)(OCc1cc(-c2ccccc2)n(Cc2ccccc2)n1)C(O)=O | Reactome pathway
KEGG
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| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113806
BindingDB Entry DOI: 10.7270/Q2M61QBT |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM50606665
(Isotense | Londomin | NSC-77030 | Neoreserpan | SU...)Show SMILES [H][C@]12C[C@@H](OC(=O)c3cc(OC)c(OC(=O)OCC)c(OC)c3)[C@H](OC)[C@@H](C(=O)OC)[C@@]1([H])C[C@@]1([H])N(CCc3c1[nH]c1cc(OC)ccc31)C2 | Reactome pathway
KEGG
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113806
BindingDB Entry DOI: 10.7270/Q2M61QBT |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345281
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- isobutoxyphe...)Show SMILES CC(C)COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl Show InChI InChI=1S/C25H29ClN2O4/c1-17(2)15-31-21-10-7-9-18(12-21)23-13-20(16-32-25(3,4)24(29)30)27-28(23)14-19-8-5-6-11-22(19)26/h5-13,17H,14-16H2,1-4H3,(H,29,30) | Reactome pathway
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PC sid
UniChem
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10202350 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BPB |
More data for this
Ligand-Target Pair | |
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