Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074796 (CHEMBL3410169) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074818 (CHEMBL3410163) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074771 (CHEMBL3410153) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209895 (US9273014, 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209891 (US9273014, 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242882 (US9427442, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209896 (US9273014, 25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209874 (US9273014, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074795 (CHEMBL3410170) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074798 (CHEMBL3410168) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074799 (CHEMBL3410167) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074784 (CHEMBL3410151) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50541992 (CHEMBL4644426) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition of human Notch1 expressed in HEK293 cells coexpressing luciferase reporter measured after 20 hrs by chemiluminescence assay | ACS Med Chem Lett 11: 1257-1268 (2020) Article DOI: 10.1021/acsmedchemlett.0c00109 BindingDB Entry DOI: 10.7270/Q29K4FSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242883 (US9427442, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209876 (US9273014, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209881 (US9273014, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242890 (US9427442, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209898 (US9273014, 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209902 (US9273014, 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242885 (US9427442, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242891 (US9427442, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242880 (US9427442, 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209880 (US9273014, 11 | US9273014, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209883 (US9273014, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074813 (CHEMBL3410164) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074693 (CHEMBL3410162) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074695 (CHEMBL3410160) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074777 (CHEMBL3410152) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50541988 (CHEMBL4645821) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition of human Notch1 expressed in HEK293 cells coexpressing luciferase reporter measured after 20 hrs by chemiluminescence assay | ACS Med Chem Lett 11: 1257-1268 (2020) Article DOI: 10.1021/acsmedchemlett.0c00109 BindingDB Entry DOI: 10.7270/Q29K4FSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242873 (US9427442, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209893 (US9273014, 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242894 (US9427442, 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209892 (US9273014, 21) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209884 (US9273014, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242881 (US9427442, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209897 (US9273014, 26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242897 (US9427442, 25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242879 (US9427442, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242896 (US9427442, 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209900 (US9273014, 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM50074694 (CHEMBL3410161) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa... | Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242875 (US9427442, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209901 (US9273014, 30 | US9273014, 35) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209904 (US9273014, 33) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209886 (US9273014, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242887 (US9427442, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209878 (US9273014, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242877 (US9427442, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless (Homo sapiens (Human)) | BDBM242886 (US9427442, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag... | US Patent US9427442 (2016) BindingDB Entry DOI: 10.7270/Q2ZP452P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human)) | BDBM209889 (US9273014, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair |
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