Compile Data Set for Download or QSAR

Found 29 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 3A'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50079386 (4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol | 4-...) Show SMILES Oc1ccc(OCCN2CCC(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H25NO2/c22-19-6-8-20(9-7-19)23-15-14-21-12-10-18(11-13-21)16-17-4-2-1-3-5-17/h1-9,18,22H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088143 (1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-1,3-dihydro...) Show SMILES O=c1[nH]c2ccccc2n1CCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H27N3O/c26-22-23-20-9-4-5-10-21(20)25(22)14-6-13-24-15-11-19(12-16-24)17-18-7-2-1-3-8-18/h1-5,7-10,19H,6,11-17H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088142 (1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-...) Show SMILES Fc1ccc(CC2CCN(CCCn3c4ccccc4[nH]c3=O)CC2)cc1 Show InChI InChI=1S/C22H26FN3O/c23-19-8-6-17(7-9-19)16-18-10-14-25(15-11-18)12-3-13-26-21-5-2-1-4-20(21)24-22(26)27/h1-2,4-9,18H,3,10-16H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081744 (4-Benzyl-1-[3-(1H-pyrazol-4-yl)-prop-2-ynyl]-piper...) Show SMILES C(C#Cc1cn[nH]c1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C18H21N3/c1-2-5-16(6-3-1)13-17-8-11-21(12-9-17)10-4-7-18-14-19-20-15-18/h1-3,5-6,14-15,17H,8-13H2,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The compound was tested in vitro for activity against NR1A/2B sub type of NMDA receptor				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081746 (1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...) Show SMILES C(CN1CCC(CC1)c1ccccc1)C#Cc1cnc[nH]1 Show InChI InChI=1S/C18H21N3/c1-2-6-16(7-3-1)17-9-12-21(13-10-17)11-5-4-8-18-14-19-15-20-18/h1-3,6-7,14-15,17H,5,9-13H2,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088148 (1-[4-(4-Benzyl-piperidin-1-yl)-butyl]-1,3-dihydro-...) Show SMILES O=c1[nH]c2ccccc2n1CCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H29N3O/c27-23-24-21-10-4-5-11-22(21)26(23)15-7-6-14-25-16-12-20(13-17-25)18-19-8-2-1-3-9-19/h1-5,8-11,20H,6-7,12-18H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081750 (1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...) Show SMILES OC1(CCN(CCC#Cc2cnc[nH]2)CC1)c1ccccc1 Show InChI InChI=1S/C18H21N3O/c22-18(16-6-2-1-3-7-16)9-12-21(13-10-18)11-5-4-8-17-14-19-15-20-17/h1-3,6-7,14-15,22H,5,9-13H2,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088147 (3-[4-(4-Benzyl-piperidin-1-yl)-butyl]-imidazolidin...) Show SMILES Oc1c[nH]c(=O)n1CCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H27N3O2/c23-18-15-20-19(24)22(18)11-5-4-10-21-12-8-17(9-13-21)14-16-6-2-1-3-7-16/h1-3,6-7,15,17,23H,4-5,8-14H2,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088144 (1-[5-(4-Benzyl-piperidin-1-yl)-pentyl]-1,3-dihydro...) Show SMILES O=c1[nH]c2ccccc2n1CCCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C24H31N3O/c28-24-25-22-11-5-6-12-23(22)27(24)16-8-2-7-15-26-17-13-21(14-18-26)19-20-9-3-1-4-10-20/h1,3-6,9-12,21H,2,7-8,13-19H2,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081743 (1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...) Show SMILES Cc1ccc(CC2CCN(CCC#Cc3cnc[nH]3)CC2)cc1 Show InChI InChI=1S/C20H25N3/c1-17-5-7-18(8-6-17)14-19-9-12-23(13-10-19)11-3-2-4-20-15-21-16-22-20/h5-8,15-16,19H,3,9-14H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081749 (4-(4-Chloro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...) Show SMILES Clc1ccc(CC2CCN(CCC#Cc3cnc[nH]3)CC2)cc1 Show InChI InChI=1S/C19H22ClN3/c20-18-6-4-16(5-7-18)13-17-8-11-23(12-9-17)10-2-1-3-19-14-21-15-22-19/h4-7,14-15,17H,2,8-13H2,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088146 (3-(3-(4-benzylpiperidin-1-yl)propyl)imidazolidine-...) Show SMILES Oc1c[nH]c(=O)n1CCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C18H25N3O2/c22-17-14-19-18(23)21(17)10-4-9-20-11-7-16(8-12-20)13-15-5-2-1-3-6-15/h1-3,5-6,14,16,22H,4,7-13H2,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081751 (4-Benzyl-1-[3-(1H-imidazol-4-yl)-prop-2-ynyl]-pipe...) Show SMILES C(C#Cc1cnc[nH]1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C18H21N3/c1-2-5-16(6-3-1)13-17-8-11-21(12-9-17)10-4-7-18-14-19-15-20-18/h1-3,5-6,14-15,17H,8-13H2,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081753 (4-(4-Fluoro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...) Show SMILES Fc1ccc(CC2CCN(CCC#Cc3cnc[nH]3)CC2)cc1 Show InChI InChI=1S/C19H22FN3/c20-18-6-4-16(5-7-18)13-17-8-11-23(12-9-17)10-2-1-3-19-14-21-15-22-19/h4-7,14-15,17H,2,8-13H2,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088145 (3-(5-(4-benzylpiperidin-1-yl)pentyl)imidazolidine-...) Show SMILES Oc1c[nH]c(=O)n1CCCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H29N3O2/c24-19-16-21-20(25)23(19)12-6-2-5-11-22-13-9-18(10-14-22)15-17-7-3-1-4-8-17/h1,3-4,7-8,16,18,24H,2,5-6,9-15H2,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081745 (4-Benzyl-1-[4-(1H-pyrrol-3-yl)-but-3-ynyl]-piperid...) Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cc[nH]c1 Show InChI InChI=1S/C20H24N2/c1-2-6-18(7-3-1)16-19-10-14-22(15-11-19)13-5-4-8-20-9-12-21-17-20/h1-3,6-7,9,12,17,19,21H,5,10-11,13-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081748 (4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...) Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cnc[nH]1 Show InChI InChI=1S/C19H23N3/c1-2-6-17(7-3-1)14-18-9-12-22(13-10-18)11-5-4-8-19-15-20-16-21-19/h1-3,6-7,15-16,18H,5,9-14H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081752 (4-Benzyl-1-[3-(1H-pyrrol-3-yl)-prop-2-ynyl]-piperi...) Show SMILES C(C#Cc1cc[nH]c1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H22N2/c1-2-5-17(6-3-1)15-18-9-13-21(14-10-18)12-4-7-19-8-11-20-16-19/h1-3,5-6,8,11,16,18,20H,9-10,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081747 (4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...) Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cn[nH]c1 Show InChI InChI=1S/C19H23N3/c1-2-6-17(7-3-1)14-18-9-12-22(13-10-18)11-5-4-8-19-15-20-21-16-19/h1-3,6-7,15-16,18H,5,9-14H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088145 (3-(5-(4-benzylpiperidin-1-yl)pentyl)imidazolidine-...) Show SMILES Oc1c[nH]c(=O)n1CCCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H29N3O2/c24-19-16-21-20(25)23(19)12-6-2-5-11-22-13-9-18(10-14-22)15-17-7-3-1-4-8-17/h1,3-4,7-8,16,18,24H,2,5-6,9-15H2,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088146 (3-(3-(4-benzylpiperidin-1-yl)propyl)imidazolidine-...) Show SMILES Oc1c[nH]c(=O)n1CCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C18H25N3O2/c22-17-14-19-18(23)21(17)10-4-9-20-11-7-16(8-12-20)13-15-5-2-1-3-6-15/h1-3,5-6,14,16,22H,4,7-13H2,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50079386 (4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol | 4-...) Show SMILES Oc1ccc(OCCN2CCC(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H25NO2/c22-19-6-8-20(9-7-19)23-15-14-21-12-10-18(11-13-21)16-17-4-2-1-3-5-17/h1-9,18,22H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088148 (1-[4-(4-Benzyl-piperidin-1-yl)-butyl]-1,3-dihydro-...) Show SMILES O=c1[nH]c2ccccc2n1CCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C23H29N3O/c27-23-24-21-10-4-5-11-22(21)26(23)15-7-6-14-25-16-12-20(13-17-25)18-19-8-2-1-3-9-19/h1-5,8-11,20H,6-7,12-18H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088147 (3-[4-(4-Benzyl-piperidin-1-yl)-butyl]-imidazolidin...) Show SMILES Oc1c[nH]c(=O)n1CCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H27N3O2/c23-18-15-20-19(24)22(18)11-5-4-10-21-12-8-17(9-13-21)14-16-6-2-1-3-7-16/h1-3,6-7,15,17,23H,4-5,8-14H2,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081744 (4-Benzyl-1-[3-(1H-pyrazol-4-yl)-prop-2-ynyl]-piper...) Show SMILES C(C#Cc1cn[nH]c1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C18H21N3/c1-2-5-16(6-3-1)13-17-8-11-21(12-9-17)10-4-7-18-14-19-20-15-18/h1-3,5-6,14-15,17H,8-13H2,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088143 (1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-1,3-dihydro...) Show SMILES O=c1[nH]c2ccccc2n1CCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H27N3O/c26-22-23-20-9-4-5-10-21(20)25(22)14-6-13-24-15-11-19(12-16-24)17-18-7-2-1-3-8-18/h1-5,7-10,19H,6,11-17H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088142 (1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-...) Show SMILES Fc1ccc(CC2CCN(CCCn3c4ccccc4[nH]c3=O)CC2)cc1 Show InChI InChI=1S/C22H26FN3O/c23-19-8-6-17(7-9-19)16-18-10-14-25(15-11-18)12-3-13-26-21-5-2-1-4-20(21)24-22(26)27/h1-2,4-9,18H,3,10-16H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081742 (4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...) Show SMILES OC1(Cc2ccccc2)CCN(CCC#Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C19H23N3O/c23-19(14-17-6-2-1-3-7-17)9-12-22(13-10-19)11-5-4-8-18-15-20-16-21-18/h1-3,6-7,15-16,23H,5,9-14H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50088144 (1-[5-(4-Benzyl-piperidin-1-yl)-pentyl]-1,3-dihydro...) Show SMILES O=c1[nH]c2ccccc2n1CCCCCN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C24H31N3O/c28-24-25-22-11-5-6-12-23(22)27(24)16-8-2-7-15-26-17-13-21(14-18-26)19-20-9-3-1-4-10-20/h1,3-6,9-12,21H,2,7-8,13-19H2,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes				J Med Chem 43: 1892-7 (2000) BindingDB Entry DOI: 10.7270/Q2V40TFH
					More data for this Ligand-Target Pair