Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-enolase (Homo sapiens (Human)) | BDBM50590126 (CHEMBL5185604) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01039 BindingDB Entry DOI: 10.7270/Q2348QCK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50590127 (CHEMBL5187779) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01039 BindingDB Entry DOI: 10.7270/Q2348QCK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM204924 (SF2312) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 37.9 | n/a | n/a | n/a | n/a | 7.4 | n/a |
University of Texas MD Anderson Cancer Center | Assay Description Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In... | Nat Chem Biol 12: 1053-1058 (2016) Article DOI: 10.1038/nchembio.2195 BindingDB Entry DOI: 10.7270/Q28W3C33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM204923 (phosphonoacetohydroxamate (PhAH)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01039 BindingDB Entry DOI: 10.7270/Q2348QCK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM204923 (phosphonoacetohydroxamate (PhAH)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 53.2 | n/a | n/a | n/a | n/a | 7.4 | n/a |
University of Texas MD Anderson Cancer Center | Assay Description Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In... | Nat Chem Biol 12: 1053-1058 (2016) Article DOI: 10.1038/nchembio.2195 BindingDB Entry DOI: 10.7270/Q28W3C33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543112 (Evofosfamide | HAP-302 | TH-302) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 301 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days in presence of 1 % oxygen by crystal violet staining based spectrophotometr... | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50103566 (CHEMBL3335790) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 576 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of ENO1 (unknown origin) | Bioorg Med Chem Lett 24: 4915-25 (2014) Article DOI: 10.1016/j.bmcl.2014.09.041 BindingDB Entry DOI: 10.7270/Q25Q4XV9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543110 (CHEMBL4647008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 604 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543110 (CHEMBL4647008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days in presence of 21 % oxygen by crystal violet staining based spectrophotomet... | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543112 (Evofosfamide | HAP-302 | TH-302) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 897 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days in presence of 1 % oxygen by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543110 (CHEMBL4647008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days in presence of 1 % oxygen by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543110 (CHEMBL4647008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543110 (CHEMBL4647008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days in presence of 21 % oxygen by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543112 (Evofosfamide | HAP-302 | TH-302) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days in presence of 21 % oxygen by crystal violet staining based spectrophotomet... | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50590125 (CHEMBL5193347) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01039 BindingDB Entry DOI: 10.7270/Q2348QCK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543110 (CHEMBL4647008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days in presence of 1 % oxygen by crystal violet staining based spectrophotometr... | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543111 (CHEMBL4633981) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543111 (CHEMBL4633981) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543112 (Evofosfamide | HAP-302 | TH-302) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days in presence of 21 % oxygen by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543113 (CHEMBL4643988) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days in presence of 1 % oxygen by crystal violet staining based spectrophotometr... | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543109 (CHEMBL4647387) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01039 BindingDB Entry DOI: 10.7270/Q2348QCK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543113 (CHEMBL4643988) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days in presence of 1 % oxygen by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543113 (CHEMBL4643988) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days in presence of 21 % oxygen by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543113 (CHEMBL4643988) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days in presence of 21 % oxygen by crystal violet staining based spectrophotomet... | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543109 (CHEMBL4647387) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in overexpressed human D423 cells incubated for 5 days by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-enolase (Homo sapiens (Human)) | BDBM50543109 (CHEMBL4647387) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of ENO1 in wild-type human LN319 cells incubated for 5 days by crystal violet staining based spectrophotometry | ACS Med Chem Lett 11: 1484-1489 (2020) Article DOI: 10.1021/acsmedchemlett.0c00203 BindingDB Entry DOI: 10.7270/Q2SB499G | |||||||||||
More data for this Ligand-Target Pair |