Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Agonist activity against Nicotinic acetylcholine receptor (nAchR) | J Med Chem 42: 1481-500 (1999) Article DOI: 10.1021/jm9805034 BindingDB Entry DOI: 10.7270/Q2HX1DCV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Rattus norvegicus) | BDBM50547502 (CHEMBL4793300) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.184 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat alpha1beta1epsilondelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00957 BindingDB Entry DOI: 10.7270/Q27S7SCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111638 (CHEMBL16044 | N-[(S)-1-(11-Amino-undecylcarbamoyl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111638 (CHEMBL16044 | N-[(S)-1-(11-Amino-undecylcarbamoyl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50094299 (CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50094299 (CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111636 (CHEMBL16259 | N-[(S)-1-(8-Amino-octylcarbamoyl)-2-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111639 (CHEMBL16184 | N-[(S)-1-(7-Amino-heptylcarbamoyl)-2...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111640 (CHEMBL16607 | N-[(S)-1-(10-Amino-decylcarbamoyl)-2...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111636 (CHEMBL16259 | N-[(S)-1-(8-Amino-octylcarbamoyl)-2-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111639 (CHEMBL16184 | N-[(S)-1-(7-Amino-heptylcarbamoyl)-2...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111637 (CHEMBL279418 | N-[(S)-1-(9-Amino-nonylcarbamoyl)-2...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50111637 (CHEMBL279418 | N-[(S)-1-(9-Amino-nonylcarbamoyl)-2...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Homo sapiens (Human)) | BDBM50094298 (CHEMBL16117 | N-[(S)-1-{3-[4-(3-Amino-propylamino)...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expres... | Bioorg Med Chem Lett 12: 1159-62 (2002) BindingDB Entry DOI: 10.7270/Q2BC3XWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50061563 (4-Acetyl-1,1-dimethyl-1,2,3,6-tetrahydro-pyridiniu...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potency and efficacy at human muscle type Nicotinic acetylcholine receptor in TE671 cells | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50049756 (3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridine |...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potency and efficacy at human Nicotinic acetylcholine receptor ganglionic type on IMR-32 cells | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50143282 ((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic) | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50056147 (2-Methyl-3-((S)-1-pyrrolidin-2-ylmethoxy)-pyridine...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor subtype TE671 (muscle) | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50061562 ((12R,13aR)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+6 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor subtype TE671 (muscle) | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic) | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50369150 (CHEMBL1788226) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a |
SIBIA Neurosciences Inc. Curated by PDSP Ki Database | Assay Description The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona... | J Med Chem 39: 3235-7 (1996) Article DOI: 10.1021/jm960328w BindingDB Entry DOI: 10.7270/Q2BV7H97 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50369150 (CHEMBL1788226) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a |
SIBIA Neurosciences Inc. Curated by PDSP Ki Database | Assay Description The compound was tested on recombinant human alpha3-beta4 cell lines of HUman embryonic kidney for nicotinic acetylcholine receptor agonist functiona... | J Med Chem 39: 3235-7 (1996) Article DOI: 10.1021/jm960328w BindingDB Entry DOI: 10.7270/Q2BV7H97 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Rattus norvegicus) | BDBM50211195 (CHEMBL3944506) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Agonist activity at rat alpha1beta1deltaepsilon nAChR expressed in HEK293 cells for 2 mins by FLIPR assay | J Med Chem 59: 11171-11181 (2016) Article DOI: 10.1021/acs.jmedchem.6b01506 BindingDB Entry DOI: 10.7270/Q2NS0X2H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50061561 (CHEMBL132966 | Methyl-((E)-4-pyridin-3-yl-but-3-en...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic) | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic) | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM50035398 ((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.11E+5 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor subtype TE671 (muscle) | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholine receptor subunit delta (Torpedo californica) | BDBM10759 (2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic) | J Med Chem 40: 4169-94 (1998) Article DOI: 10.1021/jm970377o BindingDB Entry DOI: 10.7270/Q2QF8TH9 | |||||||||||
More data for this Ligand-Target Pair |