Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1973-2420]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241823 (US9416139, 1 | US9416139, 2) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C52H60N8O7/c1-29(2)43(56-50(64)66-5)48(62)59-23-9-11-41(59)45-53-28-40(55-45)32-15-13-31(14-16-32)34-18-19-35(38-27-52(26-37(34)38)21-7-8-22-52)33-17-20-39-36(25-33)47(61)58-46(54-39)42-12-10-24-60(42)49(63)44(30(3)4)57-51(65)67-6/h13-20,25,28-30,41-44H,7-12,21-24,26-27H2,1-6H3,(H,56,64)(H,57,65)/b34-31-,35-33-,40-32-/t41-,42-,43-,44-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.760	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241858 (US9416139, 36) Show SMILES COC(=O)NC(C(C)C)C(=O)N1CCCC1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2c(c1)N=C(NC2(C)C)C1CCCN1C(=O)C(NC(=O)OC)C(C)C |c:53| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.438	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241825 (US9416139, 3) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2c(c1)N=C(NC2(C)C)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r,c:53| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.537	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241826 (US9416139, 4) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2c(c1)N=C(NC21COC1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r,c:53| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0890	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241827 (US9416139, 5) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2c(c1)N=C(NS2(=O)=O)C1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r,c:53| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0780	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241828 (US9416139, 6) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1nc2ccc(cc2c(=O)[nH]1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C51H58N8O8/c1-27(2)41(54-49(64)66-5)47(62)58-21-9-11-39(58)43-52-37-17-13-29(23-33(37)45(60)56-43)31-15-16-32(36-26-51(25-35(31)36)19-7-8-20-51)30-14-18-38-34(24-30)46(61)57-44(53-38)40-12-10-22-59(40)48(63)42(28(3)4)55-50(65)67-6/h13-18,23-24,27-28,39-42H,7-12,19-22,25-26H2,1-6H3,(H,54,64)(H,55,65)/b31-29-,32-30+/t39-,40-,41-,42-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.109	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241829 (US9416139, 7) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)C#Cc1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C48H56N8O7/c1-27(2)39(52-46(60)62-5)44(58)55-21-9-11-37(55)41-49-26-31(50-41)16-13-29-14-17-32(35-25-48(24-34(29)35)19-7-8-20-48)30-15-18-36-33(23-30)43(57)54-42(51-36)38-12-10-22-56(38)45(59)40(28(3)4)53-47(61)63-6/h14-15,17-18,23,26-28,37-40H,7-12,19-22,24-25H2,1-6H3,(H,52,60)(H,53,61)/b31-29+,32-30-/t37-,38-,39-,40-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.210	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241830 (US9416139, 8) Show SMILES CCC(C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1nc(=O)c2cc(ccc2[nH]1)-c1ccc(c2CC3(Cc12)CCCCC3)-c1ccc(cc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C54H64N8O7/c1-7-32(4)46(59-53(67)69-6)51(65)62-26-12-14-44(62)48-56-41-22-19-35(27-38(41)49(63)60-48)37-21-20-36(39-28-54(29-40(37)39)23-9-8-10-24-54)33-15-17-34(18-16-33)42-30-55-47(57-42)43-13-11-25-61(43)50(64)45(31(2)3)58-52(66)68-5/h15-22,27,30-32,43-46H,7-14,23-26,28-29H2,1-6H3,(H,58,66)(H,59,67)/b36-33-,37-35-,42-34-/t32?,43-,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.982	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241831 (US9416139, 9) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H](F)C[C@H]1c1nc(c[nH]1)-c1ccc(cc1)-c1ccc(c2CC3(Cc12)CCCCC3)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1C[C@H](F)CN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C53H60F2N8O7/c1-28(2)44(59-51(67)69-5)49(65)62-26-33(54)21-42(62)46-56-25-41(58-46)31-12-10-30(11-13-31)35-15-16-36(39-24-53(23-38(35)39)18-8-7-9-19-53)32-14-17-40-37(20-32)48(64)61-47(57-40)43-22-34(55)27-63(43)50(66)45(29(3)4)60-52(68)70-6/h10-17,20,25,28-29,33-34,42-45H,7-9,18-19,21-24,26-27H2,1-6H3,(H,59,67)(H,60,68)/b35-30-,36-32-,41-31+/t33-,34-,42-,43-,44-,45-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.439	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241832 (US9416139, 10 | US9416139, 11) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(Cc12)CCN(C)CC3)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC2CC2N1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C54H63N9O7/c1-29(2)45(58-52(67)69-6)50(65)62-20-8-9-42(62)47-55-28-41(57-47)32-12-10-31(11-13-32)35-15-16-36(39-27-54(26-38(35)39)18-21-61(5)22-19-54)33-14-17-40-37(23-33)49(64)60-48(56-40)44-25-34-24-43(34)63(44)51(66)46(30(3)4)59-53(68)70-7/h10-17,23,28-30,34,42-46H,8-9,18-22,24-27H2,1-7H3,(H,58,67)(H,59,68)/b35-31-,36-33-,41-32-/t34?,42-,43?,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.27	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241832 (US9416139, 10 | US9416139, 11) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(Cc12)CCN(C)CC3)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC2CC2N1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C54H63N9O7/c1-29(2)45(58-52(67)69-6)50(65)62-20-8-9-42(62)47-55-28-41(57-47)32-12-10-31(11-13-32)35-15-16-36(39-27-54(26-38(35)39)18-21-61(5)22-19-54)33-14-17-40-37(23-33)49(64)60-48(56-40)44-25-34-24-43(34)63(44)51(66)46(30(3)4)59-53(68)70-7/h10-17,23,28-30,34,42-46H,8-9,18-22,24-27H2,1-7H3,(H,58,67)(H,59,68)/b35-31-,36-33-,41-32-/t34?,42-,43?,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0680	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241834 (US9416139, 12) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CC(F)(F)CC1c1nc(c[nH]1)-c1ccc(cc1)-c1ccc(c2CC3(Cc12)CCOCC3)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC(F)(F)CN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C52H56F4N8O8/c1-27(2)41(60-48(68)70-5)46(66)63-25-51(53,54)22-39(63)43-57-24-38(59-43)30-9-7-29(8-10-30)32-12-13-33(36-21-50(20-35(32)36)15-17-72-18-16-50)31-11-14-37-34(19-31)45(65)62-44(58-37)40-23-52(55,56)26-64(40)47(67)42(28(3)4)61-49(69)71-6/h7-14,19,24,27-28,39-42H,15-18,20-23,25-26H2,1-6H3,(H,60,68)(H,61,69)/b32-29-,33-31-,38-30+/t39?,40-,41-,42-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.380	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241835 (US9416139, 13) Show SMILES COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C58H56N8O7/c1-72-56(70)62-49(37-13-5-3-6-14-37)54(68)65-29-11-17-47(65)51-59-34-46(61-51)36-21-19-35(20-22-36)40-24-25-41(44-33-58(32-43(40)44)27-9-10-28-58)39-23-26-45-42(31-39)53(67)64-52(60-45)48-18-12-30-66(48)55(69)50(63-57(71)73-2)38-15-7-4-8-16-38/h3-8,13-16,19-26,31,34,47-50H,9-12,17-18,27-30,32-33H2,1-2H3,(H,62,70)(H,63,71)/b40-35-,41-39-,46-36+/t47-,48-,49-,50-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.07	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241836 (US9416139, 14) Show SMILES COC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)OC |r| Show InChI InChI=1S/C48H52N8O7/c1-27(50-46(60)62-3)44(58)55-21-7-9-39(55)41-49-26-38(53-41)30-13-11-29(12-14-30)32-16-17-33(36-25-48(24-35(32)36)19-5-6-20-48)31-15-18-37-34(23-31)43(57)54-42(52-37)40-10-8-22-56(40)45(59)28(2)51-47(61)63-4/h11-18,23,26-28,39-40H,5-10,19-22,24-25H2,1-4H3,(H,50,60)(H,51,61)/b32-29-,33-31+,38-30-/t27-,28-,39-,40-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.884	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241837 (US9416139, 15) Show SMILES COC(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C1CCCCC1 |r| Show InChI InChI=1S/C58H68N8O7/c1-72-56(70)62-49(37-13-5-3-6-14-37)54(68)65-29-11-17-47(65)51-59-34-46(61-51)36-21-19-35(20-22-36)40-24-25-41(44-33-58(32-43(40)44)27-9-10-28-58)39-23-26-45-42(31-39)53(67)64-52(60-45)48-18-12-30-66(48)55(69)50(63-57(71)73-2)38-15-7-4-8-16-38/h19-26,31,34,37-38,47-50H,3-18,27-30,32-33H2,1-2H3,(H,62,70)(H,63,71)/b40-35-,41-39+,46-36-/t47-,48-,49-,50-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.206	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241838 (US9416139, 16) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)C1CCCC[C@H]1c1nc2ccc(cc2c(=O)[nH]1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc(cc1)-c1cnc([nH]1)C1CCCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C55H65N7O7/c1-31(2)46(59-53(66)68-5)48(63)38-13-7-8-14-39(38)49-57-43-23-20-35(27-40(43)51(64)61-49)37-22-21-36(41-28-55(29-42(37)41)24-10-11-25-55)33-16-18-34(19-17-33)44-30-56-50(58-44)45-15-9-12-26-62(45)52(65)47(32(3)4)60-54(67)69-6/h16-23,27,30-32,38-39,45-47H,7-15,24-26,28-29H2,1-6H3,(H,59,66)(H,60,67)/b36-33-,37-35+,44-34-/t38?,39-,45?,46+,47+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0890	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241839 (US9416139, 17) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1C[C@@H](C)C[C@H]1c1nc2ccc(cc2c(=O)[nH]1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc(cc1)C1=C[N](=CN1)[C@@H]1C[C@H](C)CN1C(=O)[C@@H](NC(=O)OC)C(C)C |r,c:56,t:54| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0230	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241840 (US9416139, 18) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CC(C)(C)C[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC(C)(C)CN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C56H68N8O7/c1-31(2)45(60-52(68)70-9)50(66)63-29-54(5,6)26-43(63)47-57-28-42(59-47)34-15-13-33(14-16-34)36-18-19-37(40-25-56(24-39(36)40)21-11-12-22-56)35-17-20-41-38(23-35)49(65)62-48(58-41)44-27-55(7,8)30-64(44)51(67)46(32(3)4)61-53(69)71-10/h13-20,23,28,31-32,43-46H,11-12,21-22,24-27,29-30H2,1-10H3,(H,60,68)(H,61,69)/b36-33-,37-35-,42-34-/t43-,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.326	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241841 (US9416139, 19) Show SMILES CC(C)[C@H](NC(=O)Oc1ccccc1)C(=O)N1CC(C)(C)C[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC(C)(C)CN1C(=O)[C@@H](NC(=O)Oc1ccccc1)C(C)C |r| Show InChI InChI=1S/C66H72N8O7/c1-39(2)55(70-62(78)80-44-17-11-9-12-18-44)60(76)73-37-64(5,6)34-53(73)57-67-36-52(69-57)42-23-21-41(22-24-42)46-26-27-47(50-33-66(32-49(46)50)29-15-16-30-66)43-25-28-51-48(31-43)59(75)72-58(68-51)54-35-65(7,8)38-74(54)61(77)56(40(3)4)71-63(79)81-45-19-13-10-14-20-45/h9-14,17-28,31,36,39-40,53-56H,15-16,29-30,32-35,37-38H2,1-8H3,(H,70,78)(H,71,79)/b46-41-,47-43-,52-42-/t53-,54-,55-,56-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.77	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241842 (US9416139, 20) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.67	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241843 (US9416139, 21) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CC2(CC2)C[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC2(CC2)CN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C56H64N8O7/c1-31(2)45(60-52(68)70-5)50(66)63-29-55(19-20-55)26-43(63)47-57-28-42(59-47)34-11-9-33(10-12-34)36-14-15-37(40-25-54(24-39(36)40)17-7-8-18-54)35-13-16-41-38(23-35)49(65)62-48(58-41)44-27-56(21-22-56)30-64(44)51(67)46(32(3)4)61-53(69)71-6/h9-16,23,28,31-32,43-46H,7-8,17-22,24-27,29-30H2,1-6H3,(H,60,68)(H,61,69)/b36-33-,37-35-,42-34+/t43-,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241844 (US9416139, 22) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1C2CC2C[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC2CC2N1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C54H60N8O7/c1-27(2)45(58-52(66)68-5)50(64)61-41-20-32(41)22-43(61)47-55-26-40(57-47)30-11-9-29(10-12-30)34-14-15-35(38-25-54(24-37(34)38)17-7-8-18-54)31-13-16-39-36(19-31)49(63)60-48(56-39)44-23-33-21-42(33)62(44)51(65)46(28(3)4)59-53(67)69-6/h9-16,19,26-28,32-33,41-46H,7-8,17-18,20-25H2,1-6H3,(H,58,66)(H,59,67)/b34-29-,35-31+,40-30-/t32?,33?,41?,42?,43-,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.561	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241845 (US9416139, 23) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1[C@H]2CC[C@H](C2)N1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C56H64N8O7/c1-29(2)45(60-54(68)70-5)52(66)63-36-16-13-34(23-36)47(63)49-57-28-44(59-49)32-11-9-31(10-12-32)38-18-19-39(42-27-56(26-41(38)42)21-7-8-22-56)33-15-20-43-40(25-33)51(65)62-50(58-43)48-35-14-17-37(24-35)64(48)53(67)46(30(3)4)61-55(69)71-6/h9-12,15,18-20,25,28-30,34-37,45-48H,7-8,13-14,16-17,21-24,26-27H2,1-6H3,(H,60,68)(H,61,69)/b38-31-,39-33+,44-32-/t34-,35-,36+,37+,45-,46-,47-,48-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.310	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241846 (US9416139, 24) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1nc2ccc(cc2c(=O)[nH]1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc(cc1)-c1cnc([nH]1)[C@@H]1CC2(CN1C(=O)[C@@H](NC(=O)OC)C(C)C)OCCO2 |r| Show InChI InChI=1S/C54H62N8O9/c1-30(2)44(58-51(66)68-5)49(64)61-21-9-10-42(61)47-56-40-18-15-34(24-37(40)48(63)60-47)36-17-16-35(38-25-53(26-39(36)38)19-7-8-20-53)32-11-13-33(14-12-32)41-28-55-46(57-41)43-27-54(70-22-23-71-54)29-62(43)50(65)45(31(3)4)59-52(67)69-6/h11-18,24,28,30-31,42-45H,7-10,19-23,25-27,29H2,1-6H3,(H,58,66)(H,59,67)/b35-32-,36-34+,41-33-/t42-,43-,44-,45-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.475	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241847 (US9416139, 25) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(c2CCCc12)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC2CC2N1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C56H64N8O7/c1-29(2)47(60-54(68)70-5)52(66)63-22-10-13-44(63)49-57-28-43(59-49)38-18-17-36(34-11-9-12-35(34)38)37-16-15-33(40-26-56(27-41(37)40)20-7-8-21-56)31-14-19-42-39(23-31)51(65)62-50(58-42)46-25-32-24-45(32)64(46)53(67)48(30(3)4)61-55(69)71-6/h14-19,23,28-30,32,44-48H,7-13,20-22,24-27H2,1-6H3,(H,60,68)(H,61,69)/b33-31+,37-36-,43-38+/t32?,44-,45?,46-,47-,48-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.829	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241848 (US9416139, 26) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(-c2ccc(c3CC4(CCCC4)Cc23)-c2ccc3nc([nH]c(=O)c3c2)[C@@H]2CC3CC3N2C(=O)[C@@H](NC(=O)OC)C(C)C)c2ccccc12 |r| Show InChI InChI=1S/C57H62N8O7/c1-30(2)48(61-55(69)71-5)53(67)64-23-11-14-45(64)50-58-29-44(60-50)39-19-18-37(35-12-7-8-13-36(35)39)38-17-16-34(41-27-57(28-42(38)41)21-9-10-22-57)32-15-20-43-40(24-32)52(66)63-51(59-43)47-26-33-25-46(33)65(47)54(68)49(31(3)4)62-56(70)72-6/h7-8,12-13,15-20,24,29-31,33,45-49H,9-11,14,21-23,25-28H2,1-6H3,(H,61,69)(H,62,70)/b34-32+,38-37-,44-39+/t33?,45-,46?,47-,48-,49-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.727	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241849 (US9416139, 27) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(-c2ccc(c3CC4(CCCC4)Cc23)-c2ccc3nc([nH]c(=O)c3c2)[C@@H]2CC3CC3N2C(=O)[C@@H](NC(=O)OC)C(C)C)c2cnoc12 |r| Show InChI InChI=1S/C54H59N9O8/c1-27(2)44(59-52(67)69-5)50(65)62-19-9-10-41(62)47-55-26-40(58-47)34-15-14-33(38-25-56-71-46(34)38)32-13-12-31(36-23-54(24-37(32)36)17-7-8-18-54)29-11-16-39-35(20-29)49(64)61-48(57-39)43-22-30-21-42(30)63(43)51(66)45(28(3)4)60-53(68)70-6/h11-16,20,25-28,30,41-45H,7-10,17-19,21-24H2,1-6H3,(H,59,67)(H,60,68)/b31-29+,33-32-,40-34+/t30?,41-,42?,43-,44-,45-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.53	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241850 (US9416139, 28) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1sc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C50H58N8O7S/c1-27(2)39(54-48(62)64-5)46(60)57-21-9-11-37(57)43-51-26-36(53-43)29-13-15-30(16-14-29)41-33-24-50(19-7-8-20-50)25-34(33)42(66-41)31-17-18-35-32(23-31)45(59)56-44(52-35)38-12-10-22-58(38)47(61)40(28(3)4)55-49(63)65-6/h13-18,23,26-28,37-40H,7-12,19-22,24-25H2,1-6H3,(H,54,62)(H,55,63)/b36-29-,41-30-,42-31-/t37-,38-,39-,40-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241851 (US9416139, 29) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ncc(c2CC3(CCCC3)Cc12)-c1ccc2c(c1)N=C(NS2(=O)=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r,c:53| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0610	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241852 (US9416139, 30) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(c2CCCc12)-c1ncc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C53H63N9O6/c1-29(2)44(59-51(65)67-5)49(63)61-22-10-14-42(61)47-55-28-41(58-47)34-17-18-35(33-13-9-12-32(33)34)46-37-26-53(20-7-8-21-53)25-36(37)38(27-54-46)31-16-19-39-40(24-31)57-48(56-39)43-15-11-23-62(43)50(64)45(30(3)4)60-52(66)68-6/h16-19,24,27-30,42-45H,7-15,20-23,25-26H2,1-6H3,(H,59,65)(H,60,66)/b38-31+,41-34+,46-35+/t42-,43-,44-,45-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.336	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241853 (US9416139, 31) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(-c2ncc(c3CC4(CCCC4)Cc23)-c2ccc3nc([nH]c3c2)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)C(C)C)c2ccccc12 |r| Show InChI InChI=1S/C54H61N9O6/c1-30(2)45(60-52(66)68-5)50(64)62-23-11-15-43(62)48-56-29-42(59-48)35-18-19-36(34-14-8-7-13-33(34)35)47-38-27-54(21-9-10-22-54)26-37(38)39(28-55-47)32-17-20-40-41(25-32)58-49(57-40)44-16-12-24-63(44)51(65)46(31(3)4)61-53(67)69-6/h7-8,13-14,17-20,25,28-31,43-46H,9-12,15-16,21-24,26-27H2,1-6H3,(H,60,66)(H,61,67)/b39-32-,42-35-,47-36+/t43-,44-,45-,46-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.87	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241854 (US9416139, 32) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(-c2sc(c3CC4(CCCC4)Cc23)-c2ccc3nc([nH]c3c2)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)C(C)C)c2cnoc12 |r| Show InChI InChI=1S/C50H57N9O7S/c1-26(2)39(56-48(62)64-5)46(60)58-19-9-11-37(58)44-51-25-36(55-44)30-15-14-29(33-24-52-66-41(30)33)43-32-23-50(17-7-8-18-50)22-31(32)42(67-43)28-13-16-34-35(21-28)54-45(53-34)38-12-10-20-59(38)47(61)40(27(3)4)57-49(63)65-6/h13-16,21,24-27,37-40H,7-12,17-20,22-23H2,1-6H3,(H,56,62)(H,57,63)/b36-30+,42-28-,43-29+/t37-,38-,39-,40-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10.3	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241855 (US9416139, 33) Show SMILES COC(=O)NC(C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(nc1)-c1cc(F)c(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C51H58FN9O7/c1-27(2)42(57-49(65)67-5)47(63)60-19-9-11-39(60)44-54-26-38(56-44)30-14-15-36(53-25-30)31-22-35(52)41(34-24-51(23-33(31)34)17-7-8-18-51)29-13-16-37-32(21-29)46(62)59-45(55-37)40-12-10-20-61(40)48(64)43(28(3)4)58-50(66)68-6/h13-16,21-22,25-28,39-40,42-43H,7-12,17-20,23-24H2,1-6H3,(H,57,65)(H,58,66)/b36-31-,38-30+,41-29-/t39-,40-,42?,43-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0780	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241856 (US9416139, 34) Show SMILES COC(=O)NC(C(C)C)C(=O)N1CCC[C@@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C52H60N8O7/c1-29(2)43(56-50(64)66-5)48(62)59-23-9-11-41(59)45-53-28-40(55-45)32-15-13-31(14-16-32)34-18-19-35(38-27-52(26-37(34)38)21-7-8-22-52)33-17-20-39-36(25-33)47(61)58-46(54-39)42-12-10-24-60(42)49(63)44(30(3)4)57-51(65)67-6/h13-20,25,28-30,41-44H,7-12,21-24,26-27H2,1-6H3,(H,56,64)(H,57,65)/b34-31-,35-33-,40-32+/t41-,42+,43?,44+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.641	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241857 (US9416139, 35) Show SMILES COC(=O)NC(C(C)C)C(=O)N1CCCC1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2[nH]c(cc(=O)c2c1)C1CCCN1C(=O)C(NC(=O)OC)C(C)C Show InChI InChI=1S/C53H61N7O7/c1-30(2)46(57-51(64)66-5)49(62)59-23-9-11-43(59)41-26-45(61)37-25-34(17-20-40(37)55-41)36-19-18-35(38-27-53(28-39(36)38)21-7-8-22-53)32-13-15-33(16-14-32)42-29-54-48(56-42)44-12-10-24-60(44)50(63)47(31(3)4)58-52(65)67-6/h13-20,25-26,29-31,43-44,46-47H,7-12,21-24,27-28H2,1-6H3,(H,57,64)(H,58,65)/b35-32-,36-34-,42-33-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10.6	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair
Genome polyprotein [1973-2420] (Hepatitis C virus genotype 1a (HCV))	BDBM241823 (US9416139, 1 | US9416139, 2) Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(CCCC3)Cc12)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r| Show InChI InChI=1S/C52H60N8O7/c1-29(2)43(56-50(64)66-5)48(62)59-23-9-11-41(59)45-53-28-40(55-45)32-15-13-31(14-16-32)34-18-19-35(38-27-52(26-37(34)38)21-7-8-22-52)33-17-20-39-36(25-33)47(61)58-46(54-39)42-12-10-24-60(42)49(63)44(30(3)4)57-51(65)67-6/h13-20,25,28-30,41-44H,7-12,21-24,26-27H2,1-6H3,(H,56,64)(H,57,65)/b34-31-,35-33-,40-32-/t41-,42-,43-,44-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.28	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...				US Patent US9416139 (2016) BindingDB Entry DOI: 10.7270/Q2Q81C0T
					More data for this Ligand-Target Pair