Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pannexin-1 (Mus musculus) | BDBM50574566 (CHEMBL4855581) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50574568 (CHEBI:82411 | CHEMBL3184128) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50574567 (CHEMBL4847247) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50574565 (CHEMBL4858078) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50247012 (3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50574563 (CHEMBL4862099) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50574564 (CHEMBL4849404) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50574562 (CHEMBL4873114) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50485599 (5-NITRO-2-PHENYLPROPYLAMINOBENZOIC ACID [NPPB] | C...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Homo sapiens (Human)) | BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Manchester Curated by ChEMBL | Assay Description Binding affinity to pannexin 1 channel (unknown origin) | J Med Chem 59: 1691-710 (2016) Article DOI: 10.1021/acs.jmedchem.5b01091 BindingDB Entry DOI: 10.7270/Q2416ZZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pannexin-1 (Mus musculus) | BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse Panx-1 expressed in Xenopus laevis oocytes assessed as inhibition of membrane current cells held at -60 mV and voltage steps to +... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113650 BindingDB Entry DOI: 10.7270/Q25T3Q8V | |||||||||||
More data for this Ligand-Target Pair |