Compile Data Set for Download or QSAR

Found 178 hits Enz. Inhib. hit(s) with Target = 'Pituitary adenylate cyclase-activating polypeptide type I receptor'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50110068 (3-Chloro-4-hydroxy-benzoic acid [1-[4-(4-isopropyl...) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(O)c(Cl)c2)cc(OC)c1OCc1ccc(cc1)C(C)C Show InChI InChI=1S/C26H27ClN2O5/c1-16(2)19-7-5-17(6-8-19)15-34-25-23(32-3)11-18(12-24(25)33-4)14-28-29-26(31)20-9-10-22(30)21(27)13-20/h5-14,16,30H,15H2,1-4H3,(H,29,31)/b28-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50122102 (3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetrame...) Show SMILES Cc1cc(C)c(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(c4)C#N)cccc23)c1C Show InChI InChI=1S/C28H26N4O2/c1-17-12-18(2)20(4)25(19(17)3)16-32-11-10-24-22(6-5-7-26(24)32)15-30-31-28(34)21-8-9-27(33)23(13-21)14-29/h5-13,15,33H,16H2,1-4H3,(H,31,34)/b30-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374178 (CHEMBL411120) Show SMILES Oc1ccc(cc1Cl)C(=O)N\N=C\c1cccc2n(Cc3cccc(c3)C(F)(F)F)ccc12 Show InChI InChI=1S/C24H17ClF3N3O2/c25-20-12-16(7-8-22(20)32)23(33)30-29-13-17-4-2-6-21-19(17)9-10-31(21)14-15-3-1-5-18(11-15)24(26,27)28/h1-13,32H,14H2,(H,30,33)/b29-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374184 (CHEMBL270677) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(O)c(Cl)c2)cc(OC)c1OCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H20ClF3N2O5/c1-33-20-9-15(12-29-30-23(32)16-5-8-19(31)18(25)11-16)10-21(34-2)22(20)35-13-14-3-6-17(7-4-14)24(26,27)28/h3-12,31H,13H2,1-2H3,(H,30,32)/b29-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374179 (CHEMBL409325) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(O)c(Cl)c2)cc(OCc2ccc(cc2)C(C)C)c1OC Show InChI InChI=1S/C26H27ClN2O5/c1-16(2)19-7-5-17(6-8-19)15-34-24-12-18(11-23(32-3)25(24)33-4)14-28-29-26(31)20-9-10-22(30)21(27)13-20/h5-14,16,30H,15H2,1-4H3,(H,29,31)/b28-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	152	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374188 (CHEMBL270226) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(O)c(Cl)c2)cc(OCc2c(C)c(C)cc(C)c2C)c1OC Show InChI InChI=1S/C27H29ClN2O5/c1-15-9-16(2)18(4)21(17(15)3)14-35-25-11-19(10-24(33-5)26(25)34-6)13-29-30-27(32)20-7-8-23(31)22(28)12-20/h7-13,31H,14H2,1-6H3,(H,30,32)/b29-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	167	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374187 (CHEMBL256379) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(O)c(Cl)c2)cc(OC)c1OCc1ccccc1 Show InChI InChI=1S/C23H21ClN2O5/c1-29-20-10-16(13-25-26-23(28)17-8-9-19(27)18(24)12-17)11-21(30-2)22(20)31-14-15-6-4-3-5-7-15/h3-13,27H,14H2,1-2H3,(H,26,28)/b25-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374177 (CHEMBL409729) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(O)c(Cl)c2)cc(OC)c1OCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H20ClF3N2O5/c1-33-20-9-15(12-29-30-23(32)16-6-7-19(31)18(25)11-16)10-21(34-2)22(20)35-13-14-4-3-5-17(8-14)24(26,27)28/h3-12,31H,13H2,1-2H3,(H,30,32)/b29-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	204	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374180 (CHEMBL404071) Show SMILES Oc1ccc(cc1Cl)C(=O)N\N=C\c1cccc(COc2ccc(cc2)C(F)(F)F)c1 Show InChI InChI=1S/C22H16ClF3N2O3/c23-19-11-16(4-9-20(19)29)21(30)28-27-12-14-2-1-3-15(10-14)13-31-18-7-5-17(6-8-18)22(24,25)26/h1-12,29H,13H2,(H,28,30)/b27-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	241	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374186 (CHEMBL272122) Show SMILES Oc1ccc(cc1Cl)C(=O)N\N=C\c1cccc(COc2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C22H16ClF3N2O3/c23-19-10-16(7-8-20(19)29)21(30)28-27-12-14-3-1-4-15(9-14)13-31-18-6-2-5-17(11-18)22(24,25)26/h1-12,29H,13H2,(H,28,30)/b27-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	274	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374183 (CHEMBL269990) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(O)c(Cl)c2)ccc1OCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H18ClF3N2O4/c1-32-21-10-14(12-28-29-22(31)16-6-7-19(30)18(24)11-16)5-8-20(21)33-13-15-3-2-4-17(9-15)23(25,26)27/h2-12,30H,13H2,1H3,(H,29,31)/b28-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	404	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374182 (CHEMBL272118) Show SMILES Oc1ccc(cc1Cl)C(=O)N\N=C\c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H17ClN2O3/c22-19-12-17(8-11-20(19)25)21(26)24-23-13-15-6-9-18(10-7-15)27-14-16-4-2-1-3-5-16/h1-13,25H,14H2,(H,24,26)/b23-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	522	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374181 (CHEMBL256837) Show SMILES Oc1ccc(cc1Cl)C(=O)N\N=C\c1ccc(OCc2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C22H16ClF3N2O3/c23-19-11-16(6-9-20(19)29)21(30)28-27-12-14-4-7-18(8-5-14)31-13-15-2-1-3-17(10-15)22(24,25)26/h1-12,29H,13H2,(H,28,30)/b27-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50374185 (CHEMBL255824) Show SMILES Oc1ccc(cc1Cl)C(=O)N\N=C\c1cccc(OCc2cccc(c2)C(F)(F)F)c1 Show InChI InChI=1S/C22H16ClF3N2O3/c23-19-11-16(7-8-20(19)29)21(30)28-27-12-14-3-2-6-18(10-14)31-13-15-4-1-5-17(9-15)22(24,25)26/h1-12,29H,13H2,(H,28,30)/b27-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	554	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50110055 (3-Chloro-4-hydroxy-benzoic acid [1-(4-isopropyl-be...) Show SMILES CC(C)c1ccc(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(Cl)c4)cccc23)cc1 Show InChI InChI=1S/C26H24ClN3O2/c1-17(2)19-8-6-18(7-9-19)16-30-13-12-22-21(4-3-5-24(22)30)15-28-29-26(32)20-10-11-25(31)23(27)14-20/h3-15,17,31H,16H2,1-2H3,(H,29,32)/b28-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	604	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cells				Bioorg Med Chem Lett 18: 2162-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.052 BindingDB Entry DOI: 10.7270/Q22J6CQ0
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50550811 (CHEMBL4740931) Show SMILES Clc1cccc2c(n[nH]c12)N1CC(CC1=O)C(=O)NCCc1c[nH]cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	<0.0100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at PAC1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced inhibition of CREB phosphorylati...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111902 BindingDB Entry DOI: 10.7270/Q28K7DPJ
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50596676 (CHEMBL5203375) Show SMILES Nc1nc2NC(=O)CC(c3cccc(OC(F)(F)F)c3)c2c(=O)[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114160 BindingDB Entry DOI: 10.7270/Q2CV4NRW
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50550810 (CHEMBL4757203) Show SMILES O=C(NCCc1c[nH]cn1)C1CN(C(=O)C1)c1n[nH]c2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.182	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at PAC1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced inhibition of CREB phosphorylati...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111902 BindingDB Entry DOI: 10.7270/Q28K7DPJ
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50596675 (CHEMBL5208587) Show SMILES COc1cc(ccc1OCC=C)C1CC(=O)Nc2nc(N)[nH]c(=O)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114160 BindingDB Entry DOI: 10.7270/Q2CV4NRW
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50200209 (CHEMBL219499) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O |r,wU:4.4,121.124,63.64,139.142,12.16,152.155,81.83,168.171,189.193,98.100,48.49,202.207,26.26,49.52,214.218,wD:110.113,55.56,130.133,2.2,69.70,147.151,37.37,159.162,177.180,87.89,197.202,20.22,207.211,(-37.66,-5.64,;-37.66,-7.18,;-36.32,-7.95,;-34.99,-7.18,;-36.32,-9.49,;-37.66,-10.26,;-38.99,-9.49,;-38.99,-7.95,;-40.33,-10.26,;-41.67,-9.49,;-42.98,-10.26,;-42.98,-11.8,;-44.32,-9.49,;-44.32,-7.95,;-42.98,-7.18,;-41.65,-7.94,;-42.99,-5.63,;-45.66,-10.26,;-46.99,-9.49,;-46.99,-7.95,;-48.33,-10.26,;-48.33,-11.8,;-46.99,-12.57,;-49.66,-9.49,;-51,-10.26,;-51,-11.8,;-52.33,-9.49,;-53.65,-10.26,;-52.33,-7.95,;-51,-7.18,;-49.53,-7.67,;-48.61,-6.44,;-49.49,-5.18,;-50.96,-5.63,;-34.99,-10.26,;-34.99,-11.8,;-33.65,-9.49,;-32.32,-10.26,;-32.32,-11.8,;-30.98,-12.57,;-30.99,-14.11,;-29.65,-14.88,;-28.32,-14.11,;-28.33,-12.56,;-29.66,-11.8,;-30.98,-9.49,;-30.98,-7.95,;-29.66,-10.26,;-28.33,-9.49,;-28.33,-7.95,;-29.66,-7.18,;-26.99,-7.18,;-26.99,-10.26,;-26.99,-11.8,;-25.65,-9.49,;-24.32,-10.26,;-24.32,-11.8,;-22.98,-12.57,;-22.99,-14.11,;-21.65,-11.8,;-22.98,-9.49,;-22.98,-7.95,;-21.65,-10.26,;-20.31,-9.49,;-20.31,-7.95,;-18.99,-7.18,;-18.99,-10.26,;-18.99,-11.8,;-17.66,-9.49,;-16.32,-10.26,;-16.32,-11.8,;-14.99,-12.57,;-14.99,-14.11,;-13.66,-14.88,;-12.32,-14.11,;-10.98,-14.88,;-12.33,-12.56,;-13.65,-11.8,;-14.99,-9.49,;-14.99,-7.95,;-13.65,-10.26,;-12.31,-9.49,;-12.31,-7.95,;-10.97,-7.18,;-10.97,-10.26,;-10.97,-11.8,;-9.64,-9.49,;-8.31,-10.26,;-8.31,-11.8,;-6.97,-12.57,;-6.97,-14.11,;-5.64,-14.88,;-5.64,-16.42,;-4.31,-17.19,;-6.97,-17.19,;-6.97,-9.49,;-6.97,-7.95,;-5.64,-10.26,;-4.31,-9.49,;-4.31,-7.95,;-2.97,-7.18,;-1.64,-7.96,;-.31,-7.19,;-.31,-5.65,;1.02,-4.88,;-1.65,-4.88,;-2.98,-5.65,;-2.97,-10.26,;-2.97,-11.8,;-1.64,-9.49,;-.3,-10.26,;-.3,-11.8,;1.03,-12.57,;1.03,-14.11,;2.36,-14.88,;2.36,-16.42,;3.7,-17.19,;1.03,-17.19,;1.03,-9.49,;1.03,-7.95,;2.36,-10.26,;3.7,-9.49,;3.7,-7.95,;5.03,-7.18,;5.03,-5.64,;6.36,-4.87,;6.36,-3.33,;5.03,-10.26,;5.03,-11.8,;6.36,-9.49,;7.7,-10.26,;7.7,-11.8,;9.03,-12.57,;9.03,-14.11,;7.7,-14.88,;10.36,-14.88,;9.03,-9.49,;9.03,-7.95,;10.36,-10.26,;11.7,-9.49,;11.7,-7.95,;13.03,-7.18,;13.03,-5.64,;14.37,-4.87,;13.03,-10.26,;13.03,-11.8,;14.37,-9.49,;15.7,-10.26,;15.7,-11.8,;17.03,-9.49,;17.03,-7.95,;18.37,-10.26,;19.7,-9.49,;19.7,-7.95,;21.03,-7.18,;18.37,-7.18,;21.03,-10.26,;21.03,-11.8,;22.37,-9.49,;23.7,-10.26,;23.7,-11.8,;25.04,-12.57,;25.04,-14.11,;26.37,-14.88,;26.37,-16.42,;25.04,-9.49,;25.04,-7.95,;26.37,-10.26,;27.7,-9.49,;27.7,-7.95,;29.04,-7.18,;29.04,-5.64,;30.37,-4.87,;30.37,-3.33,;29.04,-10.26,;29.04,-11.8,;30.37,-9.49,;31.7,-10.26,;31.7,-11.8,;33.04,-12.57,;33.03,-14.11,;34.36,-14.88,;35.7,-14.11,;37.03,-14.88,;35.69,-12.56,;34.37,-11.8,;33.04,-9.49,;33.04,-7.95,;34.37,-10.26,;35.7,-9.49,;35.7,-7.95,;37.04,-7.18,;37.04,-5.64,;38.37,-7.95,;37.04,-10.26,;37.04,-11.8,;38.37,-9.49,;39.71,-10.26,;39.71,-11.8,;41.04,-9.49,;41.04,-7.95,;42.37,-10.26,;43.71,-9.49,;43.71,-7.95,;45.04,-10.26,;45.04,-11.8,;46.37,-9.49,;47.71,-10.26,;47.71,-11.8,;46.37,-12.57,;49.04,-12.57,;49.04,-9.49,;49.04,-7.95,;50.37,-10.26,;51.71,-9.49,;51.71,-7.95,;53.04,-7.18,;53.04,-5.64,;54.38,-7.95,;53.04,-10.26,;54.38,-9.49,;53.04,-11.8,)| Show InChI InChI=1S/C142H223N39O40S/c1-16-75(10)113(178-108(190)66-155-119(199)101(63-109(191)192)171-134(214)104(67-182)175-118(198)88(146)62-84-65-152-70-156-84)138(218)172-100(58-80-28-18-17-19-29-80)132(212)181-114(79(14)185)139(219)173-102(64-110(193)194)131(211)177-106(69-184)135(215)170-99(61-83-39-45-87(188)46-40-83)130(210)176-105(68-183)133(213)163-93(34-27-54-154-142(150)151)125(205)168-97(59-81-35-41-85(186)42-36-81)128(208)162-92(33-26-53-153-141(148)149)123(203)160-89(30-20-23-50-143)121(201)164-94(47-48-107(147)189)126(206)165-95(49-55-222-15)120(200)158-78(13)117(197)179-111(73(6)7)136(216)166-91(32-22-25-52-145)122(202)161-90(31-21-24-51-144)124(204)169-98(60-82-37-43-86(187)44-38-82)129(209)167-96(56-71(2)3)127(207)159-76(11)115(195)157-77(12)116(196)180-112(74(8)9)137(217)174-103(140(220)221)57-72(4)5/h17-19,28-29,35-46,65,70-79,88-106,111-114,182-188H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,189)(H,152,156)(H,155,199)(H,157,195)(H,158,200)(H,159,207)(H,160,203)(H,161,202)(H,162,208)(H,163,213)(H,164,201)(H,165,206)(H,166,216)(H,167,209)(H,168,205)(H,169,204)(H,170,215)(H,171,214)(H,172,218)(H,173,219)(H,174,217)(H,175,198)(H,176,210)(H,177,211)(H,178,190)(H,179,197)(H,180,196)(H,181,212)(H,191,192)(H,193,194)(H,220,221)(H4,148,149,153)(H4,150,151,154)/t75-,76-,77-,78-,79+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Displacement of [125I]PACAP27 from human PAC1 receptor expressed in CHO cells				J Med Chem 49: 7545-8 (2006) Article DOI: 10.1021/jm0609059 BindingDB Entry DOI: 10.7270/Q2VD708R
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50606528 (CHEMBL5219662) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](CCS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(C)C)C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01396 BindingDB Entry DOI: 10.7270/Q2RX9H5M
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250033 (CHEMBL525419 | [Ala7]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C202H329N63O52S/c1-18-109(12)162(262-156(277)99-229-170(289)147(95-157(278)279)256-193(312)149(100-266)259-168(287)124(210)93-119-97-223-103-230-119)198(317)258-141(88-114-40-20-19-21-41-114)185(304)234-111(14)165(284)249-148(96-158(280)281)191(310)261-151(102-268)194(313)254-145(92-118-59-67-123(272)68-60-118)189(308)260-150(101-267)192(311)243-134(51-38-83-226-201(219)220)180(299)252-143(90-116-55-63-121(270)64-56-116)187(306)242-132(49-36-81-224-199(215)216)176(295)237-127(44-24-31-76-205)173(292)245-137(70-72-153(212)274)182(301)246-138(73-85-318-17)171(290)232-113(16)167(286)263-159(106(6)7)195(314)247-130(47-27-34-79-208)175(294)238-129(46-26-33-78-207)177(296)253-144(91-117-57-65-122(271)66-58-117)188(307)250-140(87-105(4)5)184(303)233-110(13)164(283)231-112(15)166(285)264-160(107(8)9)197(316)257-139(86-104(2)3)169(288)228-98-155(276)235-126(43-23-30-75-204)172(291)239-133(50-37-82-225-200(217)218)179(298)251-142(89-115-53-61-120(269)62-54-115)186(305)241-128(45-25-32-77-206)174(293)244-136(69-71-152(211)273)181(300)240-135(52-39-84-227-202(221)222)183(302)265-161(108(10)11)196(315)248-131(48-28-35-80-209)178(297)255-146(94-154(213)275)190(309)236-125(163(214)282)42-22-29-74-203/h19-21,40-41,53-68,97,103-113,124-151,159-162,266-272H,18,22-39,42-52,69-96,98-102,203-210H2,1-17H3,(H2,211,273)(H2,212,274)(H2,213,275)(H2,214,282)(H,223,230)(H,228,288)(H,229,289)(H,231,283)(H,232,290)(H,233,303)(H,234,304)(H,235,276)(H,236,309)(H,237,295)(H,238,294)(H,239,291)(H,240,300)(H,241,305)(H,242,306)(H,243,311)(H,244,293)(H,245,292)(H,246,301)(H,247,314)(H,248,315)(H,249,284)(H,250,307)(H,251,298)(H,252,299)(H,253,296)(H,254,313)(H,255,297)(H,256,312)(H,257,316)(H,258,317)(H,259,287)(H,260,308)(H,261,310)(H,262,277)(H,263,286)(H,264,285)(H,265,302)(H,278,279)(H,280,281)(H4,215,216,224)(H4,217,218,225)(H4,219,220,226)(H4,221,222,227)/t109-,110-,111-,112-,113-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250074 (CHEMBL507480 | [Bip6]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.26,12.16,4.4,54.56,55.59,69.71,87.90,104.107,127.131,145.149,158.162,174.178,195.200,208.214,220.225,wD:20.22,2.2,37.37,61.63,75.77,93.96,116.120,136.140,153.158,165.169,183.187,203.209,213.218,(4.93,2.23,;4.93,.69,;6.26,-.08,;7.6,.69,;6.26,-1.62,;4.93,-2.39,;3.6,-1.62,;3.6,-.08,;2.26,-2.39,;.93,-1.62,;-.4,-2.39,;-.4,-3.93,;-1.74,-1.62,;-1.74,-.08,;-.4,.69,;.93,-.08,;-.4,2.23,;-3.07,-2.39,;-4.4,-1.62,;-4.4,-.08,;-5.74,-2.39,;-5.74,-3.93,;-4.4,-4.7,;-7.07,-1.62,;-8.41,-2.39,;-8.41,-3.93,;-9.74,-1.62,;-11.07,-2.39,;-9.74,-.08,;-8.41,.69,;-6.99,.06,;-5.96,1.21,;-6.73,2.55,;-8.24,2.23,;7.6,-2.39,;7.6,-3.93,;8.93,-1.62,;10.27,-2.39,;10.27,-3.93,;11.6,-4.7,;11.6,-6.25,;12.94,-7.02,;14.28,-6.25,;14.28,-4.7,;12.94,-3.93,;15.61,-7.01,;15.61,-8.56,;16.95,-9.33,;18.29,-8.56,;18.28,-7,;16.94,-6.24,;11.6,-1.62,;11.6,-.08,;12.93,-2.39,;14.27,-1.62,;14.27,-.08,;12.93,.69,;15.6,.69,;15.6,-2.39,;15.6,-3.93,;16.93,-1.62,;18.27,-2.39,;18.27,-3.93,;19.6,-4.7,;20.93,-3.93,;19.6,-6.24,;19.6,-1.62,;19.6,-.08,;20.93,-2.39,;22.27,-1.62,;22.27,-.08,;23.6,.69,;23.6,-2.39,;23.6,-3.93,;24.94,-1.62,;26.27,-2.39,;26.27,-3.93,;27.6,-4.7,;28.94,-3.93,;30.28,-4.7,;30.28,-6.25,;31.61,-7.02,;28.94,-7.02,;27.6,-6.25,;27.6,-1.62,;27.6,-.08,;28.94,-2.39,;30.27,-1.62,;30.27,-.08,;31.6,.69,;31.6,-2.39,;31.6,-3.93,;32.94,-1.62,;34.27,-2.39,;34.27,-3.93,;35.61,-4.7,;35.61,-6.24,;36.94,-7.01,;36.94,-8.55,;35.61,-9.32,;38.27,-9.32,;35.61,-1.62,;35.61,-.08,;36.94,-2.39,;38.27,-1.62,;38.27,-.08,;39.61,.69,;40.94,-.08,;42.28,.69,;42.28,2.24,;43.62,3.01,;40.94,3.01,;39.61,2.24,;39.61,-2.39,;39.61,-3.93,;40.94,-1.62,;42.27,-2.39,;42.27,-3.93,;43.61,-4.7,;43.61,-6.24,;44.94,-7.01,;44.94,-8.55,;43.61,-9.32,;46.27,-9.32,;43.61,-1.62,;43.61,-.08,;44.94,-2.39,;46.27,-1.62,;46.27,-.08,;47.61,.69,;47.61,2.23,;48.94,3,;48.94,4.54,;47.61,-2.39,;47.61,-3.93,;48.94,-1.62,;50.28,-2.39,;50.28,-3.93,;51.61,-4.7,;51.61,-6.24,;50.28,-7.01,;52.94,-7.01,;51.61,-1.62,;51.61,-.08,;52.94,-2.39,;54.28,-1.62,;54.28,-.08,;55.61,.69,;55.61,2.23,;56.94,3,;55.61,-2.39,;55.61,-3.93,;56.94,-1.62,;58.28,-2.39,;58.28,-3.93,;59.61,-1.62,;59.61,-.08,;60.94,-2.39,;62.28,-1.62,;62.28,-.08,;63.61,.69,;60.94,.69,;63.61,-2.39,;63.61,-3.93,;64.95,-1.62,;66.28,-2.39,;66.28,-3.93,;67.61,-4.7,;67.61,-6.24,;68.95,-7.01,;68.95,-8.55,;67.61,-1.62,;67.61,-.08,;68.95,-2.39,;70.28,-1.62,;70.28,-.08,;71.61,.69,;71.61,2.23,;72.95,3,;72.95,4.54,;71.61,-2.39,;71.61,-3.93,;72.95,-1.62,;74.28,-2.39,;74.28,-3.93,;75.61,-4.7,;76.95,-3.93,;78.29,-4.7,;78.29,-6.25,;79.63,-7.02,;76.95,-7.02,;75.61,-6.25,;75.61,-1.62,;75.61,-.08,;76.95,-2.39,;78.28,-1.62,;78.28,-.08,;79.62,.69,;79.62,2.23,;80.95,-.08,;79.62,-2.39,;79.62,-3.93,;80.95,-1.62,;82.28,-2.39,;82.28,-3.93,;83.62,-1.62,;83.62,-.08,;84.95,-2.39,;86.28,-1.62,;86.28,-.08,;87.62,-2.39,;87.62,-3.93,;88.95,-1.62,;90.29,-2.39,;90.29,-3.93,;91.62,-4.7,;88.95,-4.7,;91.62,-1.62,;91.62,-.08,;92.95,-2.39,;94.29,-1.62,;94.29,-.08,;95.62,.69,;95.62,2.23,;96.95,-.08,;95.62,-2.39,;96.95,-1.62,;95.62,-3.93,)| Show InChI InChI=1S/C148H228N40O39S/c1-16-79(10)119(185-114(197)70-162-126(207)108(67-115(198)199)179-141(222)110(71-189)182-125(206)94(152)66-90-69-159-74-163-90)145(226)180-107(62-84-35-43-89(44-36-84)88-28-18-17-19-29-88)139(220)188-120(83(14)192)146(227)181-109(68-116(200)201)138(219)184-112(73-191)142(223)178-106(65-87-41-49-93(195)50-42-87)137(218)183-111(72-190)140(221)170-99(34-27-58-161-148(157)158)132(213)176-104(63-85-37-45-91(193)46-38-85)135(216)169-98(33-26-57-160-147(155)156)130(211)167-95(30-20-23-54-149)128(209)171-100(51-52-113(153)196)133(214)172-101(53-59-228-15)127(208)165-82(13)124(205)186-117(77(6)7)143(224)173-97(32-22-25-56-151)129(210)168-96(31-21-24-55-150)131(212)177-105(64-86-39-47-92(194)48-40-86)136(217)175-103(61-76(4)5)134(215)166-80(11)122(203)164-81(12)123(204)187-118(78(8)9)144(225)174-102(121(154)202)60-75(2)3/h17-19,28-29,35-50,69,74-83,94-112,117-120,189-195H,16,20-27,30-34,51-68,70-73,149-152H2,1-15H3,(H2,153,196)(H2,154,202)(H,159,163)(H,162,207)(H,164,203)(H,165,208)(H,166,215)(H,167,211)(H,168,210)(H,169,216)(H,170,221)(H,171,209)(H,172,214)(H,173,224)(H,174,225)(H,175,217)(H,176,213)(H,177,212)(H,178,223)(H,179,222)(H,180,226)(H,181,227)(H,182,206)(H,183,218)(H,184,219)(H,185,197)(H,186,205)(H,187,204)(H,188,220)(H,198,199)(H,200,201)(H4,155,156,160)(H4,157,158,161)/t79-,80-,81-,82-,83+,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,117-,118-,119-,120-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250018 (CHEMBL524852 | PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.26,12.16,4.4,48.49,49.52,63.64,81.83,98.100,121.124,139.142,152.155,168.171,189.193,202.207,214.218,wD:20.22,2.2,37.37,55.56,69.70,87.89,110.113,130.133,147.151,159.162,177.180,197.202,207.211,(2.22,-11.33,;2.22,-12.87,;3.55,-13.64,;4.88,-12.87,;3.55,-15.18,;2.22,-15.95,;.88,-15.18,;.88,-13.64,;-.45,-15.95,;-1.79,-15.18,;-3.12,-15.95,;-3.12,-17.49,;-4.45,-15.18,;-4.45,-13.64,;-3.12,-12.87,;-1.79,-13.64,;-3.12,-11.33,;-5.79,-15.95,;-7.12,-15.18,;-7.12,-13.64,;-8.45,-15.95,;-8.45,-17.49,;-7.12,-18.26,;-9.79,-15.18,;-11.12,-15.95,;-11.12,-17.49,;-12.45,-15.18,;-13.79,-15.95,;-12.45,-13.64,;-11.12,-12.87,;-9.71,-13.5,;-8.68,-12.35,;-9.45,-11.01,;-10.96,-11.33,;4.88,-15.95,;4.88,-17.49,;6.22,-15.18,;7.55,-15.95,;7.55,-17.49,;8.88,-18.26,;10.22,-17.49,;11.56,-18.26,;11.56,-19.8,;10.22,-20.58,;8.88,-19.8,;8.88,-15.18,;8.88,-13.64,;10.22,-15.95,;11.55,-15.18,;11.55,-13.64,;10.22,-12.87,;12.89,-12.87,;12.89,-15.95,;12.89,-17.49,;14.22,-15.18,;15.55,-15.95,;15.55,-17.49,;16.89,-18.26,;18.22,-17.49,;16.89,-19.8,;16.89,-15.18,;16.89,-13.64,;18.22,-15.95,;19.55,-15.18,;19.55,-13.64,;20.89,-12.87,;20.89,-15.95,;20.89,-17.49,;22.22,-15.18,;23.55,-15.95,;23.55,-17.49,;24.89,-18.26,;26.23,-17.49,;27.57,-18.26,;27.57,-19.8,;28.9,-20.57,;26.23,-20.58,;24.89,-19.8,;24.89,-15.18,;24.89,-13.64,;26.22,-15.95,;27.56,-15.18,;27.56,-13.64,;28.89,-12.87,;28.89,-15.95,;28.89,-17.49,;30.22,-15.18,;31.56,-15.95,;31.56,-17.49,;32.89,-18.26,;32.89,-19.8,;34.22,-20.57,;34.22,-22.11,;32.89,-22.88,;35.56,-22.88,;32.89,-15.18,;32.89,-13.64,;34.22,-15.95,;35.56,-15.18,;35.56,-13.64,;36.89,-12.87,;38.23,-13.64,;39.57,-12.87,;39.57,-11.32,;40.9,-10.55,;38.23,-10.55,;36.89,-11.32,;36.89,-15.95,;36.89,-17.49,;38.23,-15.18,;39.56,-15.95,;39.56,-17.49,;40.89,-18.26,;40.89,-19.8,;42.23,-20.57,;42.23,-22.11,;40.89,-22.88,;43.56,-22.88,;40.89,-15.18,;40.89,-13.64,;42.23,-15.95,;43.56,-15.18,;43.56,-13.64,;44.89,-12.87,;44.89,-11.33,;46.23,-10.56,;46.23,-9.02,;44.89,-15.95,;44.89,-17.49,;46.23,-15.18,;47.56,-15.95,;47.56,-17.49,;48.89,-18.26,;48.89,-19.8,;47.56,-20.57,;50.23,-20.57,;48.89,-15.18,;48.89,-13.64,;50.23,-15.95,;51.56,-15.18,;51.56,-13.64,;52.9,-12.87,;52.9,-11.33,;54.23,-10.56,;52.9,-15.95,;52.9,-17.49,;54.23,-15.18,;55.56,-15.95,;55.56,-17.49,;56.9,-15.18,;56.9,-13.64,;58.23,-15.95,;59.56,-15.18,;59.56,-13.64,;60.9,-12.87,;58.23,-12.87,;60.9,-15.95,;60.9,-17.49,;62.23,-15.18,;63.57,-15.95,;63.57,-17.49,;64.9,-18.26,;64.9,-19.8,;66.23,-20.57,;66.23,-22.11,;64.9,-15.18,;64.9,-13.64,;66.23,-15.95,;67.57,-15.18,;67.57,-13.64,;68.9,-12.87,;68.9,-11.33,;70.23,-10.56,;70.23,-9.02,;68.9,-15.95,;68.9,-17.49,;70.23,-15.18,;71.57,-15.95,;71.57,-17.49,;72.9,-18.26,;74.24,-17.49,;75.58,-18.26,;75.58,-19.8,;76.91,-20.57,;74.24,-20.58,;72.9,-19.8,;72.9,-15.18,;72.9,-13.64,;74.23,-15.95,;75.57,-15.18,;75.57,-13.64,;76.9,-12.87,;76.9,-11.33,;78.24,-13.64,;76.9,-15.95,;76.9,-17.49,;78.24,-15.18,;79.57,-15.95,;79.57,-17.49,;80.9,-15.18,;80.9,-13.64,;82.24,-15.95,;83.57,-15.18,;83.57,-13.64,;84.9,-15.95,;84.9,-17.49,;86.24,-15.18,;87.57,-15.95,;87.57,-17.49,;88.91,-18.26,;86.24,-18.26,;88.91,-15.18,;88.91,-13.64,;90.24,-15.95,;91.57,-15.18,;91.57,-13.64,;92.91,-12.87,;92.91,-11.33,;94.24,-13.64,;92.91,-15.95,;94.24,-15.18,;92.91,-17.49,)| Show InChI InChI=1S/C142H224N40O39S/c1-16-75(10)113(179-108(191)66-156-120(201)102(63-109(192)193)173-135(216)104(67-183)176-119(200)88(146)62-84-65-153-70-157-84)139(220)174-101(58-80-28-18-17-19-29-80)133(214)182-114(79(14)186)140(221)175-103(64-110(194)195)132(213)178-106(69-185)136(217)172-100(61-83-39-45-87(189)46-40-83)131(212)177-105(68-184)134(215)164-93(34-27-54-155-142(151)152)126(207)170-98(59-81-35-41-85(187)42-36-81)129(210)163-92(33-26-53-154-141(149)150)124(205)161-89(30-20-23-50-143)122(203)165-94(47-48-107(147)190)127(208)166-95(49-55-222-15)121(202)159-78(13)118(199)180-111(73(6)7)137(218)167-91(32-22-25-52-145)123(204)162-90(31-21-24-51-144)125(206)171-99(60-82-37-43-86(188)44-38-82)130(211)169-97(57-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)138(219)168-96(115(148)196)56-71(2)3/h17-19,28-29,35-46,65,70-79,88-106,111-114,183-189H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,190)(H2,148,196)(H,153,157)(H,156,201)(H,158,197)(H,159,202)(H,160,209)(H,161,205)(H,162,204)(H,163,210)(H,164,215)(H,165,203)(H,166,208)(H,167,218)(H,168,219)(H,169,211)(H,170,207)(H,171,206)(H,172,217)(H,173,216)(H,174,220)(H,175,221)(H,176,200)(H,177,212)(H,178,213)(H,179,191)(H,180,199)(H,181,198)(H,182,214)(H,192,193)(H,194,195)(H4,149,150,154)(H4,151,152,155)/t75-,76-,77-,78-,79+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of Ac-[125I]-PACAP27 from recombinant human PAC1 expressed in CHO cells after 90 mins by gamma counting analysis				Eur J Med Chem 104: 106-14 (2015) Article DOI: 10.1016/j.ejmech.2015.09.017 BindingDB Entry DOI: 10.7270/Q2HH6P1F
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250034 (CHEMBL499781 | [D-His1]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:12.16,4.4,48.49,49.52,63.64,81.83,98.100,121.124,139.142,152.155,168.171,189.193,202.207,214.218,wD:26.26,20.22,2.2,37.37,55.56,69.70,87.89,110.113,130.133,147.151,159.162,177.180,197.202,207.211,(7.72,-56.18,;7.72,-57.72,;9.06,-58.49,;10.39,-57.72,;9.06,-60.03,;7.72,-60.8,;6.39,-60.03,;6.39,-58.49,;5.05,-60.8,;3.72,-60.03,;2.39,-60.8,;2.39,-62.34,;1.05,-60.03,;1.05,-58.49,;2.39,-57.72,;3.72,-58.49,;2.39,-56.18,;-.28,-60.8,;-1.61,-60.03,;-1.61,-58.49,;-2.95,-60.8,;-2.95,-62.34,;-1.61,-63.11,;-4.28,-60.03,;-5.62,-60.8,;-5.62,-62.34,;-6.95,-60.03,;-8.28,-60.8,;-6.95,-58.49,;-5.62,-57.72,;-4.2,-58.35,;-3.17,-57.2,;-3.94,-55.86,;-5.45,-56.18,;10.39,-60.8,;10.39,-62.34,;11.72,-60.03,;13.06,-60.8,;13.06,-62.34,;14.39,-63.11,;15.73,-62.34,;17.07,-63.11,;17.07,-64.66,;15.73,-65.43,;14.39,-64.66,;14.39,-60.03,;14.39,-58.49,;15.72,-60.8,;17.06,-60.03,;17.06,-58.49,;15.72,-57.72,;18.39,-57.72,;18.39,-60.8,;18.39,-62.34,;19.72,-60.03,;21.06,-60.8,;21.06,-62.34,;22.39,-63.11,;23.73,-62.34,;22.39,-64.65,;22.39,-60.03,;22.39,-58.49,;23.73,-60.8,;25.06,-60.03,;25.06,-58.49,;26.39,-57.72,;26.39,-60.8,;26.39,-62.34,;27.73,-60.03,;29.06,-60.8,;29.06,-62.34,;30.39,-63.11,;31.73,-62.34,;33.07,-63.11,;33.07,-64.66,;34.4,-65.43,;31.73,-65.43,;30.39,-64.66,;30.39,-60.03,;30.39,-58.49,;31.73,-60.8,;33.06,-60.03,;33.06,-58.49,;34.39,-57.72,;34.39,-60.8,;34.39,-62.34,;35.73,-60.03,;37.06,-60.8,;37.06,-62.34,;38.4,-63.11,;38.4,-64.65,;39.73,-65.42,;39.73,-66.96,;38.4,-67.73,;41.06,-67.73,;38.4,-60.03,;38.4,-58.49,;39.73,-60.8,;41.06,-60.03,;41.06,-58.49,;42.4,-57.72,;43.73,-58.49,;45.07,-57.72,;45.07,-56.18,;46.41,-55.41,;43.73,-55.4,;42.4,-56.18,;42.4,-60.8,;42.4,-62.34,;43.73,-60.03,;45.06,-60.8,;45.06,-62.34,;46.4,-63.11,;46.4,-64.65,;47.73,-65.42,;47.73,-66.96,;46.4,-67.73,;49.06,-67.73,;46.4,-60.03,;46.4,-58.49,;47.73,-60.8,;49.06,-60.03,;49.06,-58.49,;50.4,-57.72,;50.4,-56.18,;51.73,-55.41,;51.73,-53.87,;50.4,-60.8,;50.4,-62.34,;51.73,-60.03,;53.07,-60.8,;53.07,-62.34,;54.4,-63.11,;54.4,-64.65,;53.07,-65.42,;55.73,-65.42,;54.4,-60.03,;54.4,-58.49,;55.73,-60.8,;57.07,-60.03,;57.07,-58.49,;58.4,-57.72,;58.4,-56.18,;59.73,-55.41,;58.4,-60.8,;58.4,-62.34,;59.73,-60.03,;61.07,-60.8,;61.07,-62.34,;62.4,-60.03,;62.4,-58.49,;63.73,-60.8,;65.07,-60.03,;65.07,-58.49,;66.4,-57.72,;63.73,-57.72,;66.4,-60.8,;66.4,-62.34,;67.74,-60.03,;69.07,-60.8,;69.07,-62.34,;70.4,-63.11,;70.4,-64.65,;71.74,-65.42,;71.74,-66.96,;70.4,-60.03,;70.4,-58.49,;71.74,-60.8,;73.07,-60.03,;73.07,-58.49,;74.4,-57.72,;74.4,-56.18,;75.74,-55.41,;75.74,-53.87,;74.4,-60.8,;74.4,-62.34,;75.74,-60.03,;77.07,-60.8,;77.07,-62.34,;78.41,-63.11,;79.74,-62.34,;81.08,-63.11,;81.08,-64.66,;82.42,-65.43,;79.74,-65.43,;78.41,-64.66,;78.41,-60.03,;78.41,-58.49,;79.74,-60.8,;81.07,-60.03,;81.07,-58.49,;82.41,-57.72,;82.41,-56.18,;83.74,-58.49,;82.41,-60.8,;82.41,-62.34,;83.74,-60.03,;85.07,-60.8,;85.07,-62.34,;86.41,-60.03,;86.41,-58.49,;87.74,-60.8,;89.07,-60.03,;89.07,-58.49,;90.41,-60.8,;90.41,-62.34,;91.74,-60.03,;93.08,-60.8,;93.08,-62.34,;94.41,-63.11,;91.74,-63.11,;94.41,-60.03,;94.41,-58.49,;95.74,-60.8,;97.08,-60.03,;97.08,-58.49,;98.41,-57.72,;98.41,-56.18,;99.74,-58.49,;98.41,-60.8,;99.74,-60.03,;98.41,-62.34,)| Show InChI InChI=1S/C142H224N40O39S/c1-16-75(10)113(179-108(191)66-156-120(201)102(63-109(192)193)173-135(216)104(67-183)176-119(200)88(146)62-84-65-153-70-157-84)139(220)174-101(58-80-28-18-17-19-29-80)133(214)182-114(79(14)186)140(221)175-103(64-110(194)195)132(213)178-106(69-185)136(217)172-100(61-83-39-45-87(189)46-40-83)131(212)177-105(68-184)134(215)164-93(34-27-54-155-142(151)152)126(207)170-98(59-81-35-41-85(187)42-36-81)129(210)163-92(33-26-53-154-141(149)150)124(205)161-89(30-20-23-50-143)122(203)165-94(47-48-107(147)190)127(208)166-95(49-55-222-15)121(202)159-78(13)118(199)180-111(73(6)7)137(218)167-91(32-22-25-52-145)123(204)162-90(31-21-24-51-144)125(206)171-99(60-82-37-43-86(188)44-38-82)130(211)169-97(57-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)138(219)168-96(115(148)196)56-71(2)3/h17-19,28-29,35-46,65,70-79,88-106,111-114,183-189H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,190)(H2,148,196)(H,153,157)(H,156,201)(H,158,197)(H,159,202)(H,160,209)(H,161,205)(H,162,204)(H,163,210)(H,164,215)(H,165,203)(H,166,208)(H,167,218)(H,168,219)(H,169,211)(H,170,207)(H,171,206)(H,172,217)(H,173,216)(H,174,220)(H,175,221)(H,176,200)(H,177,212)(H,178,213)(H,179,191)(H,180,199)(H,181,198)(H,182,214)(H,192,193)(H,194,195)(H4,149,150,154)(H4,151,152,155)/t75-,76-,77-,78-,79+,88+,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250077 (CHEMBL503123 | [Nal6]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C207H333N63O53S/c1-18-111(12)166(266-160(283)101-234-174(294)151(97-161(284)285)259-197(317)153(102-271)263-172(292)128(215)95-122-99-228-105-235-122)202(322)261-149(94-121-42-35-41-120-40-19-20-43-127(120)121)195(315)270-167(115(16)274)203(323)262-152(98-162(286)287)194(314)265-155(104-273)198(318)257-148(93-119-61-69-126(278)70-62-119)192(312)264-154(103-272)196(316)247-138(53-38-85-231-206(224)225)184(304)255-146(91-117-57-65-124(276)66-58-117)190(310)246-136(51-36-83-229-204(220)221)180(300)241-131(46-23-30-78-210)177(297)249-141(72-74-157(217)280)186(306)250-142(75-87-324-17)175(295)237-114(15)171(291)267-163(108(6)7)199(319)251-134(49-26-33-81-213)179(299)242-133(48-25-32-80-212)181(301)256-147(92-118-59-67-125(277)68-60-118)191(311)253-144(89-107(4)5)188(308)238-112(13)169(289)236-113(14)170(290)268-164(109(8)9)201(321)260-143(88-106(2)3)173(293)233-100-159(282)239-130(45-22-29-77-209)176(296)243-137(52-37-84-230-205(222)223)183(303)254-145(90-116-55-63-123(275)64-56-116)189(309)245-132(47-24-31-79-211)178(298)248-140(71-73-156(216)279)185(305)244-139(54-39-86-232-207(226)227)187(307)269-165(110(10)11)200(320)252-135(50-27-34-82-214)182(302)258-150(96-158(218)281)193(313)240-129(168(219)288)44-21-28-76-208/h19-20,35,40-43,55-70,99,105-115,128-155,163-167,271-278H,18,21-34,36-39,44-54,71-98,100-104,208-215H2,1-17H3,(H2,216,279)(H2,217,280)(H2,218,281)(H2,219,288)(H,228,235)(H,233,293)(H,234,294)(H,236,289)(H,237,295)(H,238,308)(H,239,282)(H,240,313)(H,241,300)(H,242,299)(H,243,296)(H,244,305)(H,245,309)(H,246,310)(H,247,316)(H,248,298)(H,249,297)(H,250,306)(H,251,319)(H,252,320)(H,253,311)(H,254,303)(H,255,304)(H,256,301)(H,257,318)(H,258,302)(H,259,317)(H,260,321)(H,261,322)(H,262,323)(H,263,292)(H,264,312)(H,265,314)(H,266,283)(H,267,291)(H,268,290)(H,269,307)(H,270,315)(H,284,285)(H,286,287)(H4,220,221,229)(H4,222,223,230)(H4,224,225,231)(H4,226,227,232)/t111-,112-,113-,114-,115+,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,163-,164-,165-,166-,167-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250022 (CHEMBL525392 | [Ala2]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:25.25,12.16,4.4,47.48,48.51,62.63,80.82,97.99,120.123,138.141,151.154,167.170,188.192,201.206,213.217,wD:20.20,2.2,36.36,54.55,68.69,86.88,109.112,129.132,146.150,158.161,176.179,196.201,206.210,(4.02,-45.96,;4.02,-47.5,;5.35,-48.27,;6.69,-47.5,;5.35,-49.81,;4.02,-50.58,;2.69,-49.81,;2.69,-48.27,;1.35,-50.58,;.02,-49.81,;-1.32,-50.58,;-1.32,-52.12,;-2.65,-49.81,;-2.65,-48.27,;-1.32,-47.5,;.02,-48.27,;-1.32,-45.96,;-3.98,-50.58,;-5.32,-49.81,;-5.32,-48.27,;-6.65,-50.58,;-6.65,-52.12,;-7.98,-49.81,;-9.32,-50.58,;-9.32,-52.12,;-10.65,-49.81,;-11.99,-50.58,;-10.65,-48.27,;-9.32,-47.5,;-7.91,-48.13,;-6.87,-46.98,;-7.64,-45.64,;-9.16,-45.96,;6.69,-50.58,;6.69,-52.12,;8.02,-49.81,;9.35,-50.58,;9.35,-52.12,;10.69,-52.89,;12.03,-52.11,;13.36,-52.89,;13.36,-54.43,;12.03,-55.2,;10.69,-54.43,;10.69,-49.81,;10.69,-48.27,;12.02,-50.58,;13.36,-49.81,;13.36,-48.27,;12.02,-47.5,;14.69,-47.5,;14.69,-50.58,;14.69,-52.12,;16.02,-49.81,;17.36,-50.58,;17.36,-52.12,;18.69,-52.89,;20.02,-52.12,;18.69,-54.43,;18.69,-49.81,;18.69,-48.27,;20.02,-50.58,;21.36,-49.81,;21.36,-48.27,;22.69,-47.5,;22.69,-50.58,;22.69,-52.12,;24.02,-49.81,;25.36,-50.58,;25.36,-52.12,;26.69,-52.89,;28.03,-52.11,;29.37,-52.89,;29.37,-54.43,;30.7,-55.2,;28.03,-55.2,;26.69,-54.43,;26.69,-49.81,;26.69,-48.27,;28.03,-50.58,;29.36,-49.81,;29.36,-48.27,;30.69,-47.5,;30.69,-50.58,;30.69,-52.12,;32.03,-49.81,;33.36,-50.58,;33.36,-52.12,;34.69,-52.89,;34.69,-54.43,;36.03,-55.2,;36.03,-56.74,;34.69,-57.51,;37.36,-57.51,;34.69,-49.81,;34.69,-48.27,;36.03,-50.58,;37.36,-49.81,;37.36,-48.27,;38.7,-47.5,;40.03,-48.27,;41.37,-47.5,;41.37,-45.95,;42.71,-45.18,;40.03,-45.18,;38.7,-45.95,;38.7,-50.58,;38.7,-52.12,;40.03,-49.81,;41.36,-50.58,;41.36,-52.12,;42.7,-52.89,;42.7,-54.43,;44.03,-55.2,;44.03,-56.74,;42.7,-57.51,;45.36,-57.51,;42.7,-49.81,;42.7,-48.27,;44.03,-50.58,;45.36,-49.81,;45.36,-48.27,;46.7,-47.5,;46.7,-45.96,;48.03,-45.19,;48.03,-43.65,;46.7,-50.58,;46.7,-52.12,;48.03,-49.81,;49.37,-50.58,;49.37,-52.12,;50.7,-52.89,;50.7,-54.43,;49.37,-55.2,;52.03,-55.2,;50.7,-49.81,;50.7,-48.27,;52.03,-50.58,;53.37,-49.81,;53.37,-48.27,;54.7,-47.5,;54.7,-45.96,;56.03,-45.19,;54.7,-50.58,;54.7,-52.12,;56.03,-49.81,;57.37,-50.58,;57.37,-52.12,;58.7,-49.81,;58.7,-48.27,;60.04,-50.58,;61.37,-49.81,;61.37,-48.27,;62.7,-47.5,;60.04,-47.5,;62.7,-50.58,;62.7,-52.12,;64.04,-49.81,;65.37,-50.58,;65.37,-52.12,;66.7,-52.89,;66.7,-54.43,;68.04,-55.2,;68.04,-56.74,;66.7,-49.81,;66.7,-48.27,;68.04,-50.58,;69.37,-49.81,;69.37,-48.27,;70.71,-47.5,;70.71,-45.96,;72.04,-45.19,;72.04,-43.65,;70.71,-50.58,;70.71,-52.12,;72.04,-49.81,;73.37,-50.58,;73.37,-52.12,;74.71,-52.89,;76.04,-52.11,;77.38,-52.89,;77.38,-54.43,;78.72,-55.2,;76.04,-55.2,;74.71,-54.43,;74.71,-49.81,;74.71,-48.27,;76.04,-50.58,;77.37,-49.81,;77.37,-48.27,;78.71,-47.5,;78.71,-45.96,;80.04,-48.27,;78.71,-50.58,;78.71,-52.12,;80.04,-49.81,;81.37,-50.58,;81.37,-52.12,;82.71,-49.81,;82.71,-48.27,;84.04,-50.58,;85.38,-49.81,;85.38,-48.27,;86.71,-50.58,;86.71,-52.12,;88.04,-49.81,;89.38,-50.58,;89.38,-52.12,;90.71,-52.89,;88.04,-52.89,;90.71,-49.81,;90.71,-48.27,;92.04,-50.58,;93.38,-49.81,;93.38,-48.27,;94.71,-47.5,;94.71,-45.96,;96.05,-48.27,;94.71,-50.58,;96.05,-49.81,;94.71,-52.12,)| Show InChI InChI=1S/C142H224N40O38S/c1-17-75(10)113(179-108(190)67-156-121(201)103(64-109(191)192)170-117(197)77(12)159-120(200)89(146)63-85-66-153-70-157-85)139(219)175-102(59-81-29-19-18-20-30-81)134(214)182-114(80(15)185)140(220)176-104(65-110(193)194)133(213)178-106(69-184)136(216)174-101(62-84-40-46-88(188)47-41-84)132(212)177-105(68-183)135(215)165-94(35-28-55-155-142(151)152)127(207)172-99(60-82-36-42-86(186)43-37-82)130(210)164-93(34-27-54-154-141(149)150)125(205)162-90(31-21-24-51-143)123(203)166-95(48-49-107(147)189)128(208)167-96(50-56-221-16)122(202)160-79(14)119(199)180-111(73(6)7)137(217)168-92(33-23-26-53-145)124(204)163-91(32-22-25-52-144)126(206)173-100(61-83-38-44-87(187)45-39-83)131(211)171-98(58-72(4)5)129(209)161-76(11)116(196)158-78(13)118(198)181-112(74(8)9)138(218)169-97(115(148)195)57-71(2)3/h18-20,29-30,36-47,66,70-80,89-106,111-114,183-188H,17,21-28,31-35,48-65,67-69,143-146H2,1-16H3,(H2,147,189)(H2,148,195)(H,153,157)(H,156,201)(H,158,196)(H,159,200)(H,160,202)(H,161,209)(H,162,205)(H,163,204)(H,164,210)(H,165,215)(H,166,203)(H,167,208)(H,168,217)(H,169,218)(H,170,197)(H,171,211)(H,172,207)(H,173,206)(H,174,216)(H,175,219)(H,176,220)(H,177,212)(H,178,213)(H,179,190)(H,180,199)(H,181,198)(H,182,214)(H,191,192)(H,193,194)(H4,149,150,154)(H4,151,152,155)/t75-,76-,77-,78-,79-,80+,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250035 (CHEMBL525073 | [D-His1]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H331N63O53S/c1-18-109(12)162(262-156(279)99-230-170(290)147(95-157(280)281)255-193(313)149(100-267)259-168(288)124(211)93-119-97-224-103-231-119)198(318)257-145(88-114-40-20-19-21-41-114)191(311)266-163(113(16)270)199(319)258-148(96-158(282)283)190(310)261-151(102-269)194(314)253-144(92-118-59-67-123(274)68-60-118)188(308)260-150(101-268)192(312)243-134(51-38-83-227-202(220)221)180(300)251-142(90-116-55-63-121(272)64-56-116)186(306)242-132(49-36-81-225-200(216)217)176(296)237-127(44-24-31-76-206)173(293)245-137(70-72-153(213)276)182(302)246-138(73-85-320-17)171(291)233-112(15)167(287)263-159(106(6)7)195(315)247-130(47-27-34-79-209)175(295)238-129(46-26-33-78-208)177(297)252-143(91-117-57-65-122(273)66-58-117)187(307)249-140(87-105(4)5)184(304)234-110(13)165(285)232-111(14)166(286)264-160(107(8)9)197(317)256-139(86-104(2)3)169(289)229-98-155(278)235-126(43-23-30-75-205)172(292)239-133(50-37-82-226-201(218)219)179(299)250-141(89-115-53-61-120(271)62-54-115)185(305)241-128(45-25-32-77-207)174(294)244-136(69-71-152(212)275)181(301)240-135(52-39-84-228-203(222)223)183(303)265-161(108(10)11)196(316)248-131(48-28-35-80-210)178(298)254-146(94-154(214)277)189(309)236-125(164(215)284)42-22-29-74-204/h19-21,40-41,53-68,97,103-113,124-151,159-163,267-274H,18,22-39,42-52,69-96,98-102,204-211H2,1-17H3,(H2,212,275)(H2,213,276)(H2,214,277)(H2,215,284)(H,224,231)(H,229,289)(H,230,290)(H,232,285)(H,233,291)(H,234,304)(H,235,278)(H,236,309)(H,237,296)(H,238,295)(H,239,292)(H,240,301)(H,241,305)(H,242,306)(H,243,312)(H,244,294)(H,245,293)(H,246,302)(H,247,315)(H,248,316)(H,249,307)(H,250,299)(H,251,300)(H,252,297)(H,253,314)(H,254,298)(H,255,313)(H,256,317)(H,257,318)(H,258,319)(H,259,288)(H,260,308)(H,261,310)(H,262,279)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,280,281)(H,282,283)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t109-,110-,111-,112-,113+,124+,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250075 (CHEMBL526315 | [Bip6]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C209H335N63O53S/c1-18-113(12)168(268-162(285)103-236-176(296)153(99-163(286)287)261-199(319)155(104-273)265-174(294)130(217)97-125-101-230-107-237-125)204(324)263-151(92-118-53-63-124(64-54-118)123-40-20-19-21-41-123)197(317)272-169(117(16)276)205(325)264-154(100-164(288)289)196(316)267-157(106-275)200(320)259-150(96-122-61-71-129(280)72-62-122)194(314)266-156(105-274)198(318)249-140(51-38-87-233-208(226)227)186(306)257-148(94-120-57-67-127(278)68-58-120)192(312)248-138(49-36-85-231-206(222)223)182(302)243-133(44-24-31-80-212)179(299)251-143(74-76-159(219)282)188(308)252-144(77-89-326-17)177(297)239-116(15)173(293)269-165(110(6)7)201(321)253-136(47-27-34-83-215)181(301)244-135(46-26-33-82-214)183(303)258-149(95-121-59-69-128(279)70-60-121)193(313)255-146(91-109(4)5)190(310)240-114(13)171(291)238-115(14)172(292)270-166(111(8)9)203(323)262-145(90-108(2)3)175(295)235-102-161(284)241-132(43-23-30-79-211)178(298)245-139(50-37-86-232-207(224)225)185(305)256-147(93-119-55-65-126(277)66-56-119)191(311)247-134(45-25-32-81-213)180(300)250-142(73-75-158(218)281)187(307)246-141(52-39-88-234-209(228)229)189(309)271-167(112(10)11)202(322)254-137(48-28-35-84-216)184(304)260-152(98-160(220)283)195(315)242-131(170(221)290)42-22-29-78-210/h19-21,40-41,53-72,101,107-117,130-157,165-169,273-280H,18,22-39,42-52,73-100,102-106,210-217H2,1-17H3,(H2,218,281)(H2,219,282)(H2,220,283)(H2,221,290)(H,230,237)(H,235,295)(H,236,296)(H,238,291)(H,239,297)(H,240,310)(H,241,284)(H,242,315)(H,243,302)(H,244,301)(H,245,298)(H,246,307)(H,247,311)(H,248,312)(H,249,318)(H,250,300)(H,251,299)(H,252,308)(H,253,321)(H,254,322)(H,255,313)(H,256,305)(H,257,306)(H,258,303)(H,259,320)(H,260,304)(H,261,319)(H,262,323)(H,263,324)(H,264,325)(H,265,294)(H,266,314)(H,267,316)(H,268,285)(H,269,293)(H,270,292)(H,271,309)(H,272,317)(H,286,287)(H,288,289)(H4,222,223,231)(H4,224,225,232)(H4,226,227,233)(H4,228,229,234)/t113-,114-,115-,116-,117+,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,156-,157-,165-,166-,167-,168-,169-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250059 (Ac-PACAP38 | CHEMBL530563) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C205H333N63O54S/c1-19-110(12)164(264-158(282)100-231-171(292)149(96-159(283)284)257-196(317)153(103-271)262-190(311)147(236-115(17)273)94-121-98-225-104-232-121)200(321)259-146(89-116-41-21-20-22-42-116)193(314)268-165(114(16)272)201(322)260-150(97-160(285)286)192(313)263-152(102-270)195(316)255-145(93-120-60-68-125(277)69-61-120)189(310)261-151(101-269)194(315)245-135(52-39-84-228-204(221)222)181(302)253-143(91-118-56-64-123(275)65-57-118)187(308)244-133(50-37-82-226-202(217)218)177(298)239-128(45-25-32-77-208)174(295)247-138(71-73-155(214)279)183(304)248-139(74-86-323-18)172(293)234-113(15)169(290)265-161(107(6)7)197(318)249-131(48-28-35-80-211)176(297)240-130(47-27-34-79-210)178(299)254-144(92-119-58-66-124(276)67-59-119)188(309)251-141(88-106(4)5)185(306)235-111(13)167(288)233-112(14)168(289)266-162(108(8)9)199(320)258-140(87-105(2)3)170(291)230-99-157(281)237-127(44-24-31-76-207)173(294)241-134(51-38-83-227-203(219)220)180(301)252-142(90-117-54-62-122(274)63-55-117)186(307)243-129(46-26-33-78-209)175(296)246-137(70-72-154(213)278)182(303)242-136(53-40-85-229-205(223)224)184(305)267-163(109(10)11)198(319)250-132(49-29-36-81-212)179(300)256-148(95-156(215)280)191(312)238-126(166(216)287)43-23-30-75-206/h20-22,41-42,54-69,98,104-114,126-153,161-165,269-272,274-277H,19,23-40,43-53,70-97,99-103,206-212H2,1-18H3,(H2,213,278)(H2,214,279)(H2,215,280)(H2,216,287)(H,225,232)(H,230,291)(H,231,292)(H,233,288)(H,234,293)(H,235,306)(H,236,273)(H,237,281)(H,238,312)(H,239,298)(H,240,297)(H,241,294)(H,242,303)(H,243,307)(H,244,308)(H,245,315)(H,246,296)(H,247,295)(H,248,304)(H,249,318)(H,250,319)(H,251,309)(H,252,301)(H,253,302)(H,254,299)(H,255,316)(H,256,300)(H,257,317)(H,258,320)(H,259,321)(H,260,322)(H,261,310)(H,262,311)(H,263,313)(H,264,282)(H,265,290)(H,266,289)(H,267,305)(H,268,314)(H,283,284)(H,285,286)(H4,217,218,226)(H4,219,220,227)(H4,221,222,228)(H4,223,224,229)/t110-,111-,112-,113-,114+,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,161-,162-,163-,164-,165-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250019 (CHEMBL524658 | PACAP | PACAP(1-38) | PACAP-38 | PA...) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H331N63O53S/c1-18-109(12)162(262-156(279)99-230-170(290)147(95-157(280)281)255-193(313)149(100-267)259-168(288)124(211)93-119-97-224-103-231-119)198(318)257-145(88-114-40-20-19-21-41-114)191(311)266-163(113(16)270)199(319)258-148(96-158(282)283)190(310)261-151(102-269)194(314)253-144(92-118-59-67-123(274)68-60-118)188(308)260-150(101-268)192(312)243-134(51-38-83-227-202(220)221)180(300)251-142(90-116-55-63-121(272)64-56-116)186(306)242-132(49-36-81-225-200(216)217)176(296)237-127(44-24-31-76-206)173(293)245-137(70-72-153(213)276)182(302)246-138(73-85-320-17)171(291)233-112(15)167(287)263-159(106(6)7)195(315)247-130(47-27-34-79-209)175(295)238-129(46-26-33-78-208)177(297)252-143(91-117-57-65-122(273)66-58-117)187(307)249-140(87-105(4)5)184(304)234-110(13)165(285)232-111(14)166(286)264-160(107(8)9)197(317)256-139(86-104(2)3)169(289)229-98-155(278)235-126(43-23-30-75-205)172(292)239-133(50-37-82-226-201(218)219)179(299)250-141(89-115-53-61-120(271)62-54-115)185(305)241-128(45-25-32-77-207)174(294)244-136(69-71-152(212)275)181(301)240-135(52-39-84-228-203(222)223)183(303)265-161(108(10)11)196(316)248-131(48-28-35-80-210)178(298)254-146(94-154(214)277)189(309)236-125(164(215)284)42-22-29-74-204/h19-21,40-41,53-68,97,103-113,124-151,159-163,267-274H,18,22-39,42-52,69-96,98-102,204-211H2,1-17H3,(H2,212,275)(H2,213,276)(H2,214,277)(H2,215,284)(H,224,231)(H,229,289)(H,230,290)(H,232,285)(H,233,291)(H,234,304)(H,235,278)(H,236,309)(H,237,296)(H,238,295)(H,239,292)(H,240,301)(H,241,305)(H,242,306)(H,243,312)(H,244,294)(H,245,293)(H,246,302)(H,247,315)(H,248,316)(H,249,307)(H,250,299)(H,251,300)(H,252,297)(H,253,314)(H,254,298)(H,255,313)(H,256,317)(H,257,318)(H,258,319)(H,259,288)(H,260,308)(H,261,310)(H,262,279)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,280,281)(H,282,283)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t109-,110-,111-,112-,113+,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250076 (CHEMBL525613 | [Nal6]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.26,12.16,4.4,52.54,53.57,67.69,85.88,102.105,125.129,143.147,156.160,172.176,193.198,206.212,218.223,wD:20.22,2.2,37.37,59.61,73.75,91.94,114.118,134.138,151.156,163.167,181.185,201.207,211.216,(3.18,-47.37,;3.18,-48.91,;4.52,-49.68,;5.85,-48.91,;4.52,-51.22,;3.18,-51.99,;1.85,-51.22,;1.85,-49.68,;.51,-51.99,;-.82,-51.22,;-2.15,-51.99,;-2.15,-53.53,;-3.49,-51.22,;-3.49,-49.68,;-2.15,-48.91,;-.82,-49.68,;-2.15,-47.37,;-4.82,-51.99,;-6.15,-51.22,;-6.15,-49.68,;-7.49,-51.99,;-7.49,-53.53,;-6.15,-54.3,;-8.82,-51.22,;-10.16,-51.99,;-10.16,-53.53,;-11.49,-51.22,;-12.82,-51.99,;-11.49,-49.68,;-10.16,-48.91,;-8.74,-49.54,;-7.71,-48.39,;-8.48,-47.05,;-9.99,-47.38,;5.85,-51.99,;5.85,-53.53,;7.18,-51.22,;8.52,-51.99,;8.52,-53.53,;9.85,-54.3,;11.19,-53.53,;12.53,-54.3,;12.53,-55.85,;11.2,-56.62,;11.21,-58.16,;9.88,-58.95,;8.52,-58.18,;8.51,-56.63,;9.85,-55.85,;9.85,-51.22,;9.85,-49.68,;11.18,-51.99,;12.52,-51.22,;12.52,-49.68,;11.18,-48.91,;13.85,-48.91,;13.85,-51.99,;13.85,-53.53,;15.19,-51.22,;16.52,-51.99,;16.52,-53.53,;17.85,-54.3,;19.19,-53.53,;17.85,-55.84,;17.85,-51.22,;17.85,-49.68,;19.19,-51.99,;20.52,-51.22,;20.52,-49.68,;21.85,-48.91,;21.85,-51.99,;21.85,-53.53,;23.19,-51.22,;24.52,-51.99,;24.52,-53.53,;25.86,-54.3,;27.19,-53.53,;28.53,-54.3,;28.53,-55.85,;29.87,-56.62,;27.19,-56.62,;25.86,-55.85,;25.86,-51.22,;25.86,-49.68,;27.19,-51.99,;28.52,-51.22,;28.52,-49.68,;29.86,-48.91,;29.86,-51.99,;29.86,-53.53,;31.19,-51.22,;32.52,-51.99,;32.52,-53.53,;33.86,-54.3,;33.86,-55.84,;35.19,-56.61,;35.19,-58.15,;33.86,-58.92,;36.52,-58.92,;33.86,-51.22,;33.86,-49.68,;35.19,-51.99,;36.52,-51.22,;36.52,-49.68,;37.86,-48.91,;39.2,-49.69,;40.54,-48.91,;40.54,-47.37,;41.87,-46.6,;39.2,-46.6,;37.86,-47.37,;37.86,-51.99,;37.86,-53.53,;39.19,-51.22,;40.53,-51.99,;40.53,-53.53,;41.86,-54.3,;41.86,-55.84,;43.19,-56.61,;43.19,-58.15,;41.86,-58.92,;44.53,-58.92,;41.86,-51.22,;41.86,-49.68,;43.19,-51.99,;44.53,-51.22,;44.53,-49.68,;45.86,-48.91,;45.86,-47.37,;47.19,-46.6,;47.19,-45.06,;45.86,-51.99,;45.86,-53.53,;47.19,-51.22,;48.53,-51.99,;48.53,-53.53,;49.86,-54.3,;49.86,-55.84,;48.53,-56.61,;51.2,-56.61,;49.86,-51.22,;49.86,-49.68,;51.2,-51.99,;52.53,-51.22,;52.53,-49.68,;53.86,-48.91,;53.86,-47.37,;55.2,-46.6,;53.86,-51.99,;53.86,-53.53,;55.2,-51.22,;56.53,-51.99,;56.53,-53.53,;57.86,-51.22,;57.86,-49.68,;59.2,-51.99,;60.53,-51.22,;60.53,-49.68,;61.87,-48.91,;59.2,-48.91,;61.87,-51.99,;61.87,-53.53,;63.2,-51.22,;64.53,-51.99,;64.53,-53.53,;65.87,-54.3,;65.87,-55.84,;67.2,-56.61,;67.2,-58.15,;65.87,-51.22,;65.87,-49.68,;67.2,-51.99,;68.53,-51.22,;68.53,-49.68,;69.87,-48.91,;69.87,-47.37,;71.2,-46.6,;71.2,-45.06,;69.87,-51.99,;69.87,-53.53,;71.2,-51.22,;72.54,-51.99,;72.54,-53.53,;73.87,-54.3,;75.21,-53.53,;76.55,-54.3,;76.55,-55.85,;77.88,-56.62,;75.21,-56.62,;73.87,-55.85,;73.87,-51.22,;73.87,-49.68,;75.2,-51.99,;76.54,-51.22,;76.54,-49.68,;77.87,-48.91,;77.87,-47.37,;79.2,-49.68,;77.87,-51.99,;77.87,-53.53,;79.2,-51.22,;80.54,-51.99,;80.54,-53.53,;81.87,-51.22,;81.87,-49.68,;83.2,-51.99,;84.54,-51.22,;84.54,-49.68,;85.87,-51.99,;85.87,-53.53,;87.21,-51.22,;88.54,-51.99,;88.54,-53.53,;89.87,-54.3,;87.21,-54.3,;89.87,-51.22,;89.87,-49.68,;91.21,-51.99,;92.54,-51.22,;92.54,-49.68,;93.87,-48.91,;93.87,-47.37,;95.21,-49.68,;93.87,-51.99,;95.21,-51.22,;93.87,-53.53,)| Show InChI InChI=1S/C146H226N40O39S/c1-16-77(10)117(183-112(195)68-160-124(205)106(65-113(196)197)177-139(220)108(69-187)180-123(204)92(150)64-87-67-157-72-161-87)143(224)178-105(63-86-30-25-29-85-28-17-18-31-91(85)86)137(218)186-118(81(14)190)144(225)179-107(66-114(198)199)136(217)182-110(71-189)140(221)176-104(62-84-41-47-90(193)48-42-84)135(216)181-109(70-188)138(219)168-97(36-27-56-159-146(155)156)130(211)174-102(60-82-37-43-88(191)44-38-82)133(214)167-96(35-26-55-158-145(153)154)128(209)165-93(32-19-22-52-147)126(207)169-98(49-50-111(151)194)131(212)170-99(51-57-226-15)125(206)163-80(13)122(203)184-115(75(6)7)141(222)171-95(34-21-24-54-149)127(208)166-94(33-20-23-53-148)129(210)175-103(61-83-39-45-89(192)46-40-83)134(215)173-101(59-74(4)5)132(213)164-78(11)120(201)162-79(12)121(202)185-116(76(8)9)142(223)172-100(119(152)200)58-73(2)3/h17-18,25,28-31,37-48,67,72-81,92-110,115-118,187-193H,16,19-24,26-27,32-36,49-66,68-71,147-150H2,1-15H3,(H2,151,194)(H2,152,200)(H,157,161)(H,160,205)(H,162,201)(H,163,206)(H,164,213)(H,165,209)(H,166,208)(H,167,214)(H,168,219)(H,169,207)(H,170,212)(H,171,222)(H,172,223)(H,173,215)(H,174,211)(H,175,210)(H,176,221)(H,177,220)(H,178,224)(H,179,225)(H,180,204)(H,181,216)(H,182,217)(H,183,195)(H,184,203)(H,185,202)(H,186,218)(H,196,197)(H,198,199)(H4,153,154,158)(H4,155,156,159)/t77-,78-,79-,80-,81+,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,115-,116-,117-,118-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250071 (CHEMBL524683 | [Cha6]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H337N63O53S/c1-18-109(12)162(262-156(279)99-230-170(290)147(95-157(280)281)255-193(313)149(100-267)259-168(288)124(211)93-119-97-224-103-231-119)198(318)257-145(88-114-40-20-19-21-41-114)191(311)266-163(113(16)270)199(319)258-148(96-158(282)283)190(310)261-151(102-269)194(314)253-144(92-118-59-67-123(274)68-60-118)188(308)260-150(101-268)192(312)243-134(51-38-83-227-202(220)221)180(300)251-142(90-116-55-63-121(272)64-56-116)186(306)242-132(49-36-81-225-200(216)217)176(296)237-127(44-24-31-76-206)173(293)245-137(70-72-153(213)276)182(302)246-138(73-85-320-17)171(291)233-112(15)167(287)263-159(106(6)7)195(315)247-130(47-27-34-79-209)175(295)238-129(46-26-33-78-208)177(297)252-143(91-117-57-65-122(273)66-58-117)187(307)249-140(87-105(4)5)184(304)234-110(13)165(285)232-111(14)166(286)264-160(107(8)9)197(317)256-139(86-104(2)3)169(289)229-98-155(278)235-126(43-23-30-75-205)172(292)239-133(50-37-82-226-201(218)219)179(299)250-141(89-115-53-61-120(271)62-54-115)185(305)241-128(45-25-32-77-207)174(294)244-136(69-71-152(212)275)181(301)240-135(52-39-84-228-203(222)223)183(303)265-161(108(10)11)196(316)248-131(48-28-35-80-210)178(298)254-146(94-154(214)277)189(309)236-125(164(215)284)42-22-29-74-204/h53-68,97,103-114,124-151,159-163,267-274H,18-52,69-96,98-102,204-211H2,1-17H3,(H2,212,275)(H2,213,276)(H2,214,277)(H2,215,284)(H,224,231)(H,229,289)(H,230,290)(H,232,285)(H,233,291)(H,234,304)(H,235,278)(H,236,309)(H,237,296)(H,238,295)(H,239,292)(H,240,301)(H,241,305)(H,242,306)(H,243,312)(H,244,294)(H,245,293)(H,246,302)(H,247,315)(H,248,316)(H,249,307)(H,250,299)(H,251,300)(H,252,297)(H,253,314)(H,254,298)(H,255,313)(H,256,317)(H,257,318)(H,258,319)(H,259,288)(H,260,308)(H,261,310)(H,262,279)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,280,281)(H,282,283)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t109-,110-,111-,112-,113+,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250037 (CHEMBL524894 | [D-Ser2]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H331N63O53S/c1-18-109(12)162(262-156(279)99-230-170(290)147(95-157(280)281)255-193(313)149(100-267)259-168(288)124(211)93-119-97-224-103-231-119)198(318)257-145(88-114-40-20-19-21-41-114)191(311)266-163(113(16)270)199(319)258-148(96-158(282)283)190(310)261-151(102-269)194(314)253-144(92-118-59-67-123(274)68-60-118)188(308)260-150(101-268)192(312)243-134(51-38-83-227-202(220)221)180(300)251-142(90-116-55-63-121(272)64-56-116)186(306)242-132(49-36-81-225-200(216)217)176(296)237-127(44-24-31-76-206)173(293)245-137(70-72-153(213)276)182(302)246-138(73-85-320-17)171(291)233-112(15)167(287)263-159(106(6)7)195(315)247-130(47-27-34-79-209)175(295)238-129(46-26-33-78-208)177(297)252-143(91-117-57-65-122(273)66-58-117)187(307)249-140(87-105(4)5)184(304)234-110(13)165(285)232-111(14)166(286)264-160(107(8)9)197(317)256-139(86-104(2)3)169(289)229-98-155(278)235-126(43-23-30-75-205)172(292)239-133(50-37-82-226-201(218)219)179(299)250-141(89-115-53-61-120(271)62-54-115)185(305)241-128(45-25-32-77-207)174(294)244-136(69-71-152(212)275)181(301)240-135(52-39-84-228-203(222)223)183(303)265-161(108(10)11)196(316)248-131(48-28-35-80-210)178(298)254-146(94-154(214)277)189(309)236-125(164(215)284)42-22-29-74-204/h19-21,40-41,53-68,97,103-113,124-151,159-163,267-274H,18,22-39,42-52,69-96,98-102,204-211H2,1-17H3,(H2,212,275)(H2,213,276)(H2,214,277)(H2,215,284)(H,224,231)(H,229,289)(H,230,290)(H,232,285)(H,233,291)(H,234,304)(H,235,278)(H,236,309)(H,237,296)(H,238,295)(H,239,292)(H,240,301)(H,241,305)(H,242,306)(H,243,312)(H,244,294)(H,245,293)(H,246,302)(H,247,315)(H,248,316)(H,249,307)(H,250,299)(H,251,300)(H,252,297)(H,253,314)(H,254,298)(H,255,313)(H,256,317)(H,257,318)(H,258,319)(H,259,288)(H,260,308)(H,261,310)(H,262,279)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,280,281)(H,282,283)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t109-,110-,111-,112-,113+,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149+,150-,151-,159-,160-,161-,162-,163-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250073 (CHEMBL526360 | [Tyr6]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H331N63O54S/c1-18-108(12)162(262-156(280)98-230-170(291)147(94-157(281)282)255-193(314)149(99-267)259-168(289)124(211)92-118-96-224-102-231-118)198(319)257-145(91-117-56-66-123(275)67-57-117)191(312)266-163(112(16)270)199(320)258-148(95-158(283)284)190(311)261-151(101-269)194(315)253-144(90-116-54-64-122(274)65-55-116)188(309)260-150(100-268)192(313)243-134(46-35-82-227-202(220)221)180(301)251-142(88-114-50-60-120(272)61-51-114)186(307)242-132(44-33-80-225-200(216)217)176(297)237-127(39-21-28-75-206)173(294)245-137(69-71-153(213)277)182(303)246-138(72-84-321-17)171(292)233-111(15)167(288)263-159(105(6)7)195(316)247-130(42-24-31-78-209)175(296)238-129(41-23-30-77-208)177(298)252-143(89-115-52-62-121(273)63-53-115)187(308)249-140(86-104(4)5)184(305)234-109(13)165(286)232-110(14)166(287)264-160(106(8)9)197(318)256-139(85-103(2)3)169(290)229-97-155(279)235-126(38-20-27-74-205)172(293)239-133(45-34-81-226-201(218)219)179(300)250-141(87-113-48-58-119(271)59-49-113)185(306)241-128(40-22-29-76-207)174(295)244-136(68-70-152(212)276)181(302)240-135(47-36-83-228-203(222)223)183(304)265-161(107(10)11)196(317)248-131(43-25-32-79-210)178(299)254-146(93-154(214)278)189(310)236-125(164(215)285)37-19-26-73-204/h48-67,96,102-112,124-151,159-163,267-275H,18-47,68-95,97-101,204-211H2,1-17H3,(H2,212,276)(H2,213,277)(H2,214,278)(H2,215,285)(H,224,231)(H,229,290)(H,230,291)(H,232,286)(H,233,292)(H,234,305)(H,235,279)(H,236,310)(H,237,297)(H,238,296)(H,239,293)(H,240,302)(H,241,306)(H,242,307)(H,243,313)(H,244,295)(H,245,294)(H,246,303)(H,247,316)(H,248,317)(H,249,308)(H,250,300)(H,251,301)(H,252,298)(H,253,315)(H,254,299)(H,255,314)(H,256,318)(H,257,319)(H,258,320)(H,259,289)(H,260,309)(H,261,311)(H,262,280)(H,263,288)(H,264,287)(H,265,304)(H,266,312)(H,281,282)(H,283,284)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t108-,109-,110-,111-,112+,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250069 (CHEMBL524494 | [Glu3]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C204H333N63O53S/c1-18-110(12)163(263-157(280)100-230-170(290)137(71-74-158(281)282)245-193(313)150(101-268)260-169(289)125(212)95-120-98-225-104-232-120)199(319)258-147(90-115-40-20-19-21-41-115)192(312)267-164(114(16)271)200(320)259-149(97-159(283)284)191(311)262-152(103-270)195(315)255-146(94-119-59-67-124(275)68-60-119)189(309)261-151(102-269)194(314)244-135(51-38-85-228-203(221)222)181(301)253-144(92-117-55-63-122(273)64-56-117)187(307)243-133(49-36-83-226-201(217)218)177(297)238-128(44-24-31-78-207)174(294)247-139(70-73-154(214)277)183(303)248-140(75-87-321-17)172(292)234-113(15)168(288)264-160(107(6)7)196(316)249-131(47-27-34-81-210)176(296)239-130(46-26-33-80-209)178(298)254-145(93-118-57-65-123(274)66-58-118)188(308)251-142(89-106(4)5)185(305)235-111(13)166(286)233-112(14)167(287)265-161(108(8)9)198(318)257-141(88-105(2)3)171(291)231-99-156(279)236-127(43-23-30-77-206)173(293)240-134(50-37-84-227-202(219)220)180(300)252-143(91-116-53-61-121(272)62-54-116)186(306)242-129(45-25-32-79-208)175(295)246-138(69-72-153(213)276)182(302)241-136(52-39-86-229-204(223)224)184(304)266-162(109(10)11)197(317)250-132(48-28-35-82-211)179(299)256-148(96-155(215)278)190(310)237-126(165(216)285)42-22-29-76-205/h19-21,40-41,53-68,98,104-114,125-152,160-164,268-275H,18,22-39,42-52,69-97,99-103,205-212H2,1-17H3,(H2,213,276)(H2,214,277)(H2,215,278)(H2,216,285)(H,225,232)(H,230,290)(H,231,291)(H,233,286)(H,234,292)(H,235,305)(H,236,279)(H,237,310)(H,238,297)(H,239,296)(H,240,293)(H,241,302)(H,242,306)(H,243,307)(H,244,314)(H,245,313)(H,246,295)(H,247,294)(H,248,303)(H,249,316)(H,250,317)(H,251,308)(H,252,300)(H,253,301)(H,254,298)(H,255,315)(H,256,299)(H,257,318)(H,258,319)(H,259,320)(H,260,289)(H,261,309)(H,262,311)(H,263,280)(H,264,288)(H,265,287)(H,266,304)(H,267,312)(H,281,282)(H,283,284)(H4,217,218,226)(H4,219,220,227)(H4,221,222,228)(H4,223,224,229)/t110-,111-,112-,113-,114+,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,160-,161-,162-,163-,164-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250085 (CHEMBL506517 | [Aib2]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C204H333N63O52S/c1-20-110(12)162(262-156(279)101-231-170(290)148(97-157(280)281)261-199(319)204(17,18)267-168(288)125(212)95-120-99-225-104-232-120)197(317)257-146(90-115-42-22-21-23-43-115)191(311)266-163(114(16)270)198(318)258-149(98-158(282)283)190(310)260-151(103-269)193(313)254-145(94-119-61-69-124(274)70-62-119)188(308)259-150(102-268)192(312)244-135(53-40-85-228-202(221)222)180(300)252-143(92-117-57-65-122(272)66-58-117)186(306)243-133(51-38-83-226-200(217)218)176(296)238-128(46-26-33-78-207)173(293)246-138(72-74-153(214)276)182(302)247-139(75-87-320-19)171(291)234-113(15)167(287)263-159(107(6)7)194(314)248-131(49-29-36-81-210)175(295)239-130(48-28-35-80-209)177(297)253-144(93-118-59-67-123(273)68-60-118)187(307)250-141(89-106(4)5)184(304)235-111(13)165(285)233-112(14)166(286)264-160(108(8)9)196(316)256-140(88-105(2)3)169(289)230-100-155(278)236-127(45-25-32-77-206)172(292)240-134(52-39-84-227-201(219)220)179(299)251-142(91-116-55-63-121(271)64-56-116)185(305)242-129(47-27-34-79-208)174(294)245-137(71-73-152(213)275)181(301)241-136(54-41-86-229-203(223)224)183(303)265-161(109(10)11)195(315)249-132(50-30-37-82-211)178(298)255-147(96-154(215)277)189(309)237-126(164(216)284)44-24-31-76-205/h21-23,42-43,55-70,99,104-114,125-151,159-163,268-274H,20,24-41,44-54,71-98,100-103,205-212H2,1-19H3,(H2,213,275)(H2,214,276)(H2,215,277)(H2,216,284)(H,225,232)(H,230,289)(H,231,290)(H,233,285)(H,234,291)(H,235,304)(H,236,278)(H,237,309)(H,238,296)(H,239,295)(H,240,292)(H,241,301)(H,242,305)(H,243,306)(H,244,312)(H,245,294)(H,246,293)(H,247,302)(H,248,314)(H,249,315)(H,250,307)(H,251,299)(H,252,300)(H,253,297)(H,254,313)(H,255,298)(H,256,316)(H,257,317)(H,258,318)(H,259,308)(H,260,310)(H,261,319)(H,262,279)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,267,288)(H,280,281)(H,282,283)(H4,217,218,226)(H4,219,220,227)(H4,221,222,228)(H4,223,224,229)/t110-,111-,112-,113-,114+,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250039 (CHEMBL524334 | [D-Asp3]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H331N63O53S/c1-18-109(12)162(262-156(279)99-230-170(290)147(95-157(280)281)255-193(313)149(100-267)259-168(288)124(211)93-119-97-224-103-231-119)198(318)257-145(88-114-40-20-19-21-41-114)191(311)266-163(113(16)270)199(319)258-148(96-158(282)283)190(310)261-151(102-269)194(314)253-144(92-118-59-67-123(274)68-60-118)188(308)260-150(101-268)192(312)243-134(51-38-83-227-202(220)221)180(300)251-142(90-116-55-63-121(272)64-56-116)186(306)242-132(49-36-81-225-200(216)217)176(296)237-127(44-24-31-76-206)173(293)245-137(70-72-153(213)276)182(302)246-138(73-85-320-17)171(291)233-112(15)167(287)263-159(106(6)7)195(315)247-130(47-27-34-79-209)175(295)238-129(46-26-33-78-208)177(297)252-143(91-117-57-65-122(273)66-58-117)187(307)249-140(87-105(4)5)184(304)234-110(13)165(285)232-111(14)166(286)264-160(107(8)9)197(317)256-139(86-104(2)3)169(289)229-98-155(278)235-126(43-23-30-75-205)172(292)239-133(50-37-82-226-201(218)219)179(299)250-141(89-115-53-61-120(271)62-54-115)185(305)241-128(45-25-32-77-207)174(294)244-136(69-71-152(212)275)181(301)240-135(52-39-84-228-203(222)223)183(303)265-161(108(10)11)196(316)248-131(48-28-35-80-210)178(298)254-146(94-154(214)277)189(309)236-125(164(215)284)42-22-29-74-204/h19-21,40-41,53-68,97,103-113,124-151,159-163,267-274H,18,22-39,42-52,69-96,98-102,204-211H2,1-17H3,(H2,212,275)(H2,213,276)(H2,214,277)(H2,215,284)(H,224,231)(H,229,289)(H,230,290)(H,232,285)(H,233,291)(H,234,304)(H,235,278)(H,236,309)(H,237,296)(H,238,295)(H,239,292)(H,240,301)(H,241,305)(H,242,306)(H,243,312)(H,244,294)(H,245,293)(H,246,302)(H,247,315)(H,248,316)(H,249,307)(H,250,299)(H,251,300)(H,252,297)(H,253,314)(H,254,298)(H,255,313)(H,256,317)(H,257,318)(H,258,319)(H,259,288)(H,260,308)(H,261,310)(H,262,279)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,280,281)(H,282,283)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t109-,110-,111-,112-,113+,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147+,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250036 (CHEMBL506133 | [D-Ser2]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.26,20.22,12.16,4.4,48.49,49.52,63.64,81.83,98.100,121.124,139.142,152.155,168.171,189.193,202.207,214.218,wD:2.2,37.37,55.56,69.70,87.89,110.113,130.133,147.151,159.162,177.180,197.202,207.211,(2.8,-22.25,;2.8,-23.79,;4.13,-24.56,;5.46,-23.79,;4.13,-26.1,;2.8,-26.87,;1.46,-26.1,;1.46,-24.56,;.13,-26.87,;-1.21,-26.1,;-2.54,-26.87,;-2.54,-28.41,;-3.87,-26.1,;-3.87,-24.56,;-2.54,-23.79,;-1.21,-24.56,;-2.54,-22.25,;-5.21,-26.87,;-6.54,-26.1,;-6.54,-24.56,;-7.87,-26.87,;-7.87,-28.41,;-6.54,-29.18,;-9.21,-26.1,;-10.54,-26.87,;-10.54,-28.41,;-11.87,-26.1,;-13.21,-26.87,;-11.87,-24.56,;-10.54,-23.79,;-9.13,-24.42,;-8.1,-23.27,;-8.87,-21.93,;-10.38,-22.25,;5.46,-26.87,;5.46,-28.41,;6.8,-26.1,;8.13,-26.87,;8.13,-28.41,;9.46,-29.18,;10.8,-28.41,;12.14,-29.18,;12.14,-30.72,;10.8,-31.5,;9.46,-30.72,;9.46,-26.1,;9.46,-24.56,;10.8,-26.87,;12.13,-26.1,;12.13,-24.56,;10.8,-23.79,;13.46,-23.79,;13.46,-26.87,;13.46,-28.41,;14.8,-26.1,;16.13,-26.87,;16.13,-28.41,;17.47,-29.18,;18.8,-28.41,;17.47,-30.72,;17.47,-26.1,;17.47,-24.56,;18.8,-26.87,;20.13,-26.1,;20.13,-24.56,;21.47,-23.79,;21.47,-26.87,;21.47,-28.41,;22.8,-26.1,;24.13,-26.87,;24.13,-28.41,;25.47,-29.18,;26.81,-28.41,;28.14,-29.18,;28.14,-30.72,;29.48,-31.49,;26.81,-31.5,;25.47,-30.72,;25.47,-26.1,;25.47,-24.56,;26.8,-26.87,;28.14,-26.1,;28.14,-24.56,;29.47,-23.79,;29.47,-26.87,;29.47,-28.41,;30.8,-26.1,;32.14,-26.87,;32.14,-28.41,;33.47,-29.18,;33.47,-30.72,;34.8,-31.49,;34.8,-33.03,;33.47,-33.8,;36.14,-33.8,;33.47,-26.1,;33.47,-24.56,;34.8,-26.87,;36.14,-26.1,;36.14,-24.56,;37.47,-23.79,;38.81,-24.56,;40.15,-23.79,;40.15,-22.24,;41.48,-21.47,;38.81,-21.47,;37.47,-22.24,;37.47,-26.87,;37.47,-28.41,;38.8,-26.1,;40.14,-26.87,;40.14,-28.41,;41.47,-29.18,;41.47,-30.72,;42.81,-31.49,;42.81,-33.03,;41.47,-33.8,;44.14,-33.8,;41.47,-26.1,;41.47,-24.56,;42.81,-26.87,;44.14,-26.1,;44.14,-24.56,;45.47,-23.79,;45.47,-22.25,;46.81,-21.48,;46.81,-19.94,;45.47,-26.87,;45.47,-28.41,;46.81,-26.1,;48.14,-26.87,;48.14,-28.41,;49.47,-29.18,;49.47,-30.72,;48.14,-31.49,;50.81,-31.49,;49.47,-26.1,;49.47,-24.56,;50.81,-26.87,;52.14,-26.1,;52.14,-24.56,;53.47,-23.79,;53.47,-22.25,;54.81,-21.48,;53.47,-26.87,;53.47,-28.41,;54.81,-26.1,;56.14,-26.87,;56.14,-28.41,;57.48,-26.1,;57.48,-24.56,;58.81,-26.87,;60.14,-26.1,;60.14,-24.56,;61.48,-23.79,;58.81,-23.79,;61.48,-26.87,;61.48,-28.41,;62.81,-26.1,;64.14,-26.87,;64.14,-28.41,;65.48,-29.18,;65.48,-30.72,;66.81,-31.49,;66.81,-33.03,;65.48,-26.1,;65.48,-24.56,;66.81,-26.87,;68.14,-26.1,;68.14,-24.56,;69.48,-23.79,;69.48,-22.25,;70.81,-21.48,;70.81,-19.94,;69.48,-26.87,;69.48,-28.41,;70.81,-26.1,;72.15,-26.87,;72.15,-28.41,;73.48,-29.18,;74.82,-28.41,;76.16,-29.18,;76.16,-30.72,;77.49,-31.49,;74.82,-31.5,;73.48,-30.72,;73.48,-26.1,;73.48,-24.56,;74.81,-26.87,;76.15,-26.1,;76.15,-24.56,;77.48,-23.79,;77.48,-22.25,;78.81,-24.56,;77.48,-26.87,;77.48,-28.41,;78.81,-26.1,;80.15,-26.87,;80.15,-28.41,;81.48,-26.1,;81.48,-24.56,;82.81,-26.87,;84.15,-26.1,;84.15,-24.56,;85.48,-26.87,;85.48,-28.41,;86.82,-26.1,;88.15,-26.87,;88.15,-28.41,;89.48,-29.18,;86.82,-29.18,;89.48,-26.1,;89.48,-24.56,;90.82,-26.87,;92.15,-26.1,;92.15,-24.56,;93.48,-23.79,;93.48,-22.25,;94.82,-24.56,;93.48,-26.87,;94.82,-26.1,;93.48,-28.41,)| Show InChI InChI=1S/C142H224N40O39S/c1-16-75(10)113(179-108(191)66-156-120(201)102(63-109(192)193)173-135(216)104(67-183)176-119(200)88(146)62-84-65-153-70-157-84)139(220)174-101(58-80-28-18-17-19-29-80)133(214)182-114(79(14)186)140(221)175-103(64-110(194)195)132(213)178-106(69-185)136(217)172-100(61-83-39-45-87(189)46-40-83)131(212)177-105(68-184)134(215)164-93(34-27-54-155-142(151)152)126(207)170-98(59-81-35-41-85(187)42-36-81)129(210)163-92(33-26-53-154-141(149)150)124(205)161-89(30-20-23-50-143)122(203)165-94(47-48-107(147)190)127(208)166-95(49-55-222-15)121(202)159-78(13)118(199)180-111(73(6)7)137(218)167-91(32-22-25-52-145)123(204)162-90(31-21-24-51-144)125(206)171-99(60-82-37-43-86(188)44-38-82)130(211)169-97(57-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)138(219)168-96(115(148)196)56-71(2)3/h17-19,28-29,35-46,65,70-79,88-106,111-114,183-189H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,190)(H2,148,196)(H,153,157)(H,156,201)(H,158,197)(H,159,202)(H,160,209)(H,161,205)(H,162,204)(H,163,210)(H,164,215)(H,165,203)(H,166,208)(H,167,218)(H,168,219)(H,169,211)(H,170,207)(H,171,206)(H,172,217)(H,173,216)(H,174,220)(H,175,221)(H,176,200)(H,177,212)(H,178,213)(H,179,191)(H,180,199)(H,181,198)(H,182,214)(H,192,193)(H,194,195)(H4,149,150,154)(H4,151,152,155)/t75-,76-,77-,78-,79+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104+,105-,106-,111-,112-,113-,114-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250061 (CHEMBL498948 | [His(1-Me)1]PACAP38) Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1cncn1-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#16]-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#7])=O |r| Show InChI InChI=1S/C204H333N63O53S/c1-19-110(12)163(262-157(280)100-231-171(291)148(96-158(281)282)255-194(314)150(101-268)259-169(289)125(212)94-120-98-225-104-267(120)17)199(319)257-146(89-115-41-21-20-22-42-115)192(312)266-164(114(16)271)200(320)258-149(97-159(283)284)191(311)261-152(103-270)195(315)253-145(93-119-60-68-124(275)69-61-119)189(309)260-151(102-269)193(313)243-135(52-39-84-228-203(221)222)181(301)251-143(91-117-56-64-122(273)65-57-117)187(307)242-133(50-37-82-226-201(217)218)177(297)237-128(45-25-32-77-207)174(294)245-138(71-73-154(214)277)183(303)246-139(74-86-321-18)172(292)233-113(15)168(288)263-160(107(6)7)196(316)247-131(48-28-35-80-210)176(296)238-130(47-27-34-79-209)178(298)252-144(92-118-58-66-123(274)67-59-118)188(308)249-141(88-106(4)5)185(305)234-111(13)166(286)232-112(14)167(287)264-161(108(8)9)198(318)256-140(87-105(2)3)170(290)230-99-156(279)235-127(44-24-31-76-206)173(293)239-134(51-38-83-227-202(219)220)180(300)250-142(90-116-54-62-121(272)63-55-116)186(306)241-129(46-26-33-78-208)175(295)244-137(70-72-153(213)276)182(302)240-136(53-40-85-229-204(223)224)184(304)265-162(109(10)11)197(317)248-132(49-29-36-81-211)179(299)254-147(95-155(215)278)190(310)236-126(165(216)285)43-23-30-75-205/h20-22,41-42,54-69,98,104-114,125-152,160-164,268-275H,19,23-40,43-53,70-97,99-103,205-212H2,1-18H3,(H2,213,276)(H2,214,277)(H2,215,278)(H2,216,285)(H,230,290)(H,231,291)(H,232,286)(H,233,292)(H,234,305)(H,235,279)(H,236,310)(H,237,297)(H,238,296)(H,239,293)(H,240,302)(H,241,306)(H,242,307)(H,243,313)(H,244,295)(H,245,294)(H,246,303)(H,247,316)(H,248,317)(H,249,308)(H,250,300)(H,251,301)(H,252,298)(H,253,315)(H,254,299)(H,255,314)(H,256,318)(H,257,319)(H,258,320)(H,259,289)(H,260,309)(H,261,311)(H,262,280)(H,263,288)(H,264,287)(H,265,304)(H,266,312)(H,281,282)(H,283,284)(H4,217,218,226)(H4,219,220,227)(H4,221,222,228)(H4,223,224,229)/t110-,111-,112-,113-,114+,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,160-,161-,162-,163-,164-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250078 (CHEMBL524672 | [Pro2]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:20.19,12.16,4.4,49.51,50.54,64.66,82.85,99.102,122.126,140.144,153.157,169.173,190.195,203.209,215.220,wD:2.2,38.39,56.58,70.72,88.91,111.115,131.135,148.153,160.164,178.182,198.204,208.213,27.28,(.78,-21.73,;.78,-23.27,;2.12,-24.04,;3.45,-23.27,;2.12,-25.58,;.78,-26.35,;-.55,-25.58,;-.55,-24.04,;-1.89,-26.35,;-3.22,-25.58,;-4.55,-26.35,;-4.55,-27.89,;-5.89,-25.58,;-5.89,-24.04,;-4.55,-23.27,;-3.22,-24.04,;-4.55,-21.73,;-7.22,-26.35,;-8.55,-25.58,;-8.55,-24.04,;-10.04,-25.99,;-11.25,-25.03,;-12.54,-25.88,;-12.13,-27.36,;-10.59,-27.43,;-9.74,-28.72,;-8.21,-28.63,;-10.44,-30.09,;-11.97,-30.18,;-9.59,-31.38,;-10.28,-32.76,;-9.58,-34.13,;-10.66,-35.23,;-12.04,-34.54,;-11.8,-33.02,;3.45,-26.35,;3.45,-27.89,;4.78,-25.58,;6.12,-26.35,;6.12,-27.89,;7.45,-28.66,;8.79,-27.89,;10.13,-28.66,;10.13,-30.2,;8.79,-30.98,;7.45,-30.2,;7.45,-25.58,;7.45,-24.04,;8.78,-26.35,;10.12,-25.58,;10.12,-24.04,;8.78,-23.27,;11.45,-23.27,;11.45,-26.35,;11.45,-27.89,;12.78,-25.58,;14.12,-26.35,;14.12,-27.89,;15.45,-28.66,;16.79,-27.89,;15.45,-30.2,;15.45,-25.58,;15.45,-24.04,;16.79,-26.35,;18.12,-25.58,;18.12,-24.04,;19.45,-23.27,;19.45,-26.35,;19.45,-27.89,;20.79,-25.58,;22.12,-26.35,;22.12,-27.89,;23.45,-28.66,;24.79,-27.89,;26.13,-28.66,;26.13,-30.2,;27.46,-30.97,;24.79,-30.98,;23.45,-30.2,;23.45,-25.58,;23.45,-24.04,;24.79,-26.35,;26.12,-25.58,;26.12,-24.04,;27.46,-23.27,;27.46,-26.35,;27.46,-27.89,;28.79,-25.58,;30.12,-26.35,;30.12,-27.89,;31.46,-28.66,;31.46,-30.2,;32.79,-30.97,;32.79,-32.51,;31.46,-33.28,;34.12,-33.28,;31.46,-25.58,;31.46,-24.04,;32.79,-26.35,;34.12,-25.58,;34.12,-24.04,;35.46,-23.27,;36.8,-24.04,;38.13,-23.27,;38.13,-21.72,;39.47,-20.95,;36.8,-20.95,;35.46,-21.72,;35.46,-26.35,;35.46,-27.89,;36.79,-25.58,;38.12,-26.35,;38.12,-27.89,;39.46,-28.66,;39.46,-30.2,;40.79,-30.97,;40.79,-32.51,;39.46,-33.28,;42.13,-33.28,;39.46,-25.58,;39.46,-24.04,;40.79,-26.35,;42.13,-25.58,;42.13,-24.04,;43.46,-23.27,;43.46,-21.73,;44.79,-20.96,;44.79,-19.42,;43.46,-26.35,;43.46,-27.89,;44.79,-25.58,;46.13,-26.35,;46.13,-27.89,;47.46,-28.66,;47.46,-30.2,;46.13,-30.97,;48.79,-30.97,;47.46,-25.58,;47.46,-24.04,;48.79,-26.35,;50.13,-25.58,;50.13,-24.04,;51.46,-23.27,;51.46,-21.73,;52.8,-20.96,;51.46,-26.35,;51.46,-27.89,;52.8,-25.58,;54.13,-26.35,;54.13,-27.89,;55.46,-25.58,;55.46,-24.04,;56.8,-26.35,;58.13,-25.58,;58.13,-24.04,;59.46,-23.27,;56.8,-23.27,;59.46,-26.35,;59.46,-27.89,;60.8,-25.58,;62.13,-26.35,;62.13,-27.89,;63.46,-28.66,;63.46,-30.2,;64.8,-30.97,;64.8,-32.51,;63.46,-25.58,;63.46,-24.04,;64.8,-26.35,;66.13,-25.58,;66.13,-24.04,;67.47,-23.27,;67.47,-21.73,;68.8,-20.96,;68.8,-19.42,;67.47,-26.35,;67.47,-27.89,;68.8,-25.58,;70.13,-26.35,;70.13,-27.89,;71.47,-28.66,;72.81,-27.89,;74.14,-28.66,;74.14,-30.2,;75.48,-30.97,;72.81,-30.98,;71.47,-30.2,;71.47,-25.58,;71.47,-24.04,;72.8,-26.35,;74.13,-25.58,;74.13,-24.04,;75.47,-23.27,;75.47,-21.73,;76.8,-24.04,;75.47,-26.35,;75.47,-27.89,;76.8,-25.58,;78.14,-26.35,;78.14,-27.89,;79.47,-25.58,;79.47,-24.04,;80.8,-26.35,;82.14,-25.58,;82.14,-24.04,;83.47,-26.35,;83.47,-27.89,;84.8,-25.58,;86.14,-26.35,;86.14,-27.89,;87.47,-28.66,;84.8,-28.66,;87.47,-25.58,;87.47,-24.04,;88.8,-26.35,;90.14,-25.58,;90.14,-24.04,;91.47,-23.27,;91.47,-21.73,;92.81,-24.04,;91.47,-26.35,;92.81,-25.58,;91.47,-27.89,)| Show InChI InChI=1S/C144H226N40O38S/c1-16-77(10)115(180-110(192)69-158-121(201)104(66-111(193)194)175-137(217)108-36-28-57-184(108)142(222)90(148)65-86-68-155-72-159-86)140(220)176-103(61-82-29-18-17-19-30-82)134(214)183-116(81(14)187)141(221)177-105(67-112(195)196)133(213)179-107(71-186)136(216)174-102(64-85-41-47-89(190)48-42-85)132(212)178-106(70-185)135(215)166-95(35-27-56-157-144(153)154)127(207)172-100(62-83-37-43-87(188)44-38-83)130(210)165-94(34-26-55-156-143(151)152)125(205)163-91(31-20-23-52-145)123(203)167-96(49-50-109(149)191)128(208)168-97(51-58-223-15)122(202)161-80(13)120(200)181-113(75(6)7)138(218)169-93(33-22-25-54-147)124(204)164-92(32-21-24-53-146)126(206)173-101(63-84-39-45-88(189)46-40-84)131(211)171-99(60-74(4)5)129(209)162-78(11)118(198)160-79(12)119(199)182-114(76(8)9)139(219)170-98(117(150)197)59-73(2)3/h17-19,29-30,37-48,68,72-81,90-108,113-116,185-190H,16,20-28,31-36,49-67,69-71,145-148H2,1-15H3,(H2,149,191)(H2,150,197)(H,155,159)(H,158,201)(H,160,198)(H,161,202)(H,162,209)(H,163,205)(H,164,204)(H,165,210)(H,166,215)(H,167,203)(H,168,208)(H,169,218)(H,170,219)(H,171,211)(H,172,207)(H,173,206)(H,174,216)(H,175,217)(H,176,220)(H,177,221)(H,178,212)(H,179,213)(H,180,192)(H,181,200)(H,182,199)(H,183,214)(H,193,194)(H,195,196)(H4,151,152,156)(H4,153,154,157)/t77-,78-,79-,80-,81+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,113-,114-,115-,116-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250072 (CHEMBL498867 | [Tyr6]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.26,12.16,4.4,49.50,50.53,64.65,82.84,99.101,122.125,140.143,153.156,169.172,190.194,203.208,215.219,wD:20.22,2.2,37.37,56.57,70.71,88.90,111.114,131.134,148.152,160.163,178.181,198.203,208.212,(2.88,-21.44,;2.88,-22.98,;4.22,-23.75,;5.55,-22.98,;4.22,-25.29,;2.88,-26.06,;1.55,-25.29,;1.55,-23.75,;.21,-26.06,;-1.12,-25.29,;-2.45,-26.06,;-2.45,-27.6,;-3.79,-25.29,;-3.79,-23.75,;-2.45,-22.98,;-1.12,-23.75,;-2.45,-21.44,;-5.12,-26.06,;-6.45,-25.29,;-6.45,-23.75,;-7.79,-26.06,;-7.79,-27.6,;-6.45,-28.37,;-9.12,-25.29,;-10.46,-26.06,;-10.46,-27.6,;-11.79,-25.29,;-13.12,-26.06,;-11.79,-23.75,;-10.46,-22.98,;-9.04,-23.61,;-8.01,-22.46,;-8.78,-21.13,;-10.29,-21.45,;5.55,-26.06,;5.55,-27.6,;6.88,-25.29,;8.22,-26.06,;8.22,-27.6,;9.55,-28.37,;10.89,-27.6,;12.23,-28.37,;12.23,-29.92,;13.56,-30.69,;10.89,-30.69,;9.55,-29.92,;9.55,-25.29,;9.55,-23.75,;10.88,-26.06,;12.22,-25.29,;12.22,-23.75,;10.88,-22.98,;13.55,-22.98,;13.55,-26.06,;13.55,-27.6,;14.88,-25.29,;16.22,-26.06,;16.22,-27.6,;17.55,-28.37,;18.89,-27.6,;17.55,-29.91,;17.55,-25.29,;17.55,-23.75,;18.89,-26.06,;20.22,-25.29,;20.22,-23.75,;21.55,-22.98,;21.55,-26.06,;21.55,-27.6,;22.89,-25.29,;24.22,-26.06,;24.22,-27.6,;25.55,-28.37,;26.89,-27.6,;28.23,-28.37,;28.23,-29.92,;29.56,-30.69,;26.89,-30.69,;25.55,-29.92,;25.55,-25.29,;25.55,-23.75,;26.89,-26.06,;28.22,-25.29,;28.22,-23.75,;29.55,-22.98,;29.55,-26.06,;29.55,-27.6,;30.89,-25.29,;32.22,-26.06,;32.22,-27.6,;33.56,-28.37,;33.56,-29.91,;34.89,-30.68,;34.89,-32.22,;33.56,-32.99,;36.22,-32.99,;33.56,-25.29,;33.56,-23.75,;34.89,-26.06,;36.22,-25.29,;36.22,-23.75,;37.56,-22.98,;38.89,-23.76,;40.23,-22.98,;40.23,-21.44,;41.57,-20.67,;38.89,-20.67,;37.56,-21.44,;37.56,-26.06,;37.56,-27.6,;38.89,-25.29,;40.22,-26.06,;40.22,-27.6,;41.56,-28.37,;41.56,-29.91,;42.89,-30.68,;42.89,-32.22,;41.56,-32.99,;44.22,-32.99,;41.56,-25.29,;41.56,-23.75,;42.89,-26.06,;44.22,-25.29,;44.22,-23.75,;45.56,-22.98,;45.56,-21.44,;46.89,-20.67,;46.89,-19.13,;45.56,-26.06,;45.56,-27.6,;46.89,-25.29,;48.23,-26.06,;48.23,-27.6,;49.56,-28.37,;49.56,-29.91,;48.23,-30.68,;50.89,-30.68,;49.56,-25.29,;49.56,-23.75,;50.89,-26.06,;52.23,-25.29,;52.23,-23.75,;53.56,-22.98,;53.56,-21.44,;54.89,-20.67,;53.56,-26.06,;53.56,-27.6,;54.89,-25.29,;56.23,-26.06,;56.23,-27.6,;57.56,-25.29,;57.56,-23.75,;58.89,-26.06,;60.23,-25.29,;60.23,-23.75,;61.56,-22.98,;58.89,-22.98,;61.56,-26.06,;61.56,-27.6,;62.9,-25.29,;64.23,-26.06,;64.23,-27.6,;65.56,-28.37,;65.56,-29.91,;66.9,-30.68,;66.9,-32.22,;65.56,-25.29,;65.56,-23.75,;66.9,-26.06,;68.23,-25.29,;68.23,-23.75,;69.56,-22.98,;69.56,-21.44,;70.9,-20.67,;70.9,-19.13,;69.56,-26.06,;69.56,-27.6,;70.9,-25.29,;72.23,-26.06,;72.23,-27.6,;73.57,-28.37,;74.9,-27.6,;76.24,-28.37,;76.24,-29.92,;77.58,-30.69,;74.9,-30.69,;73.57,-29.92,;73.57,-25.29,;73.57,-23.75,;74.9,-26.06,;76.23,-25.29,;76.23,-23.75,;77.57,-22.98,;77.57,-21.44,;78.9,-23.75,;77.57,-26.06,;77.57,-27.6,;78.9,-25.29,;80.23,-26.06,;80.23,-27.6,;81.57,-25.29,;81.57,-23.75,;82.9,-26.06,;84.23,-25.29,;84.23,-23.75,;85.57,-26.06,;85.57,-27.6,;86.9,-25.29,;88.24,-26.06,;88.24,-27.6,;89.57,-28.37,;86.9,-28.37,;89.57,-25.29,;89.57,-23.75,;90.9,-26.06,;92.24,-25.29,;92.24,-23.75,;93.57,-22.98,;93.57,-21.44,;94.9,-23.75,;93.57,-26.06,;94.9,-25.29,;93.57,-27.6,)| Show InChI InChI=1S/C142H224N40O40S/c1-16-74(10)113(179-108(192)65-156-120(202)102(62-109(193)194)173-135(217)104(66-183)176-119(201)88(146)61-83-64-153-69-157-83)139(221)174-101(60-82-36-44-87(190)45-37-82)133(215)182-114(78(14)186)140(222)175-103(63-110(195)196)132(214)178-106(68-185)136(218)172-100(59-81-34-42-86(189)43-35-81)131(213)177-105(67-184)134(216)164-93(29-24-53-155-142(151)152)126(208)170-98(57-79-30-38-84(187)39-31-79)129(211)163-92(28-23-52-154-141(149)150)124(206)161-89(25-17-20-49-143)122(204)165-94(46-47-107(147)191)127(209)166-95(48-54-223-15)121(203)159-77(13)118(200)180-111(72(6)7)137(219)167-91(27-19-22-51-145)123(205)162-90(26-18-21-50-144)125(207)171-99(58-80-32-40-85(188)41-33-80)130(212)169-97(56-71(4)5)128(210)160-75(11)116(198)158-76(12)117(199)181-112(73(8)9)138(220)168-96(115(148)197)55-70(2)3/h30-45,64,69-78,88-106,111-114,183-190H,16-29,46-63,65-68,143-146H2,1-15H3,(H2,147,191)(H2,148,197)(H,153,157)(H,156,202)(H,158,198)(H,159,203)(H,160,210)(H,161,206)(H,162,205)(H,163,211)(H,164,216)(H,165,204)(H,166,209)(H,167,219)(H,168,220)(H,169,212)(H,170,208)(H,171,207)(H,172,218)(H,173,217)(H,174,221)(H,175,222)(H,176,201)(H,177,213)(H,178,214)(H,179,192)(H,180,200)(H,181,199)(H,182,215)(H,193,194)(H,195,196)(H4,149,150,154)(H4,151,152,155)/t74-,75-,76-,77-,78+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250023 (CHEMBL500280 | [Ala2]PACAP(1-38) | [Ala2]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C203H331N63O52S/c1-19-109(12)162(262-156(278)100-230-171(290)148(96-157(279)280)250-166(285)111(14)233-169(288)125(211)94-120-98-224-103-231-120)198(317)258-146(89-115-41-21-20-22-42-115)192(311)266-163(114(17)269)199(318)259-149(97-158(281)282)191(310)261-151(102-268)194(313)255-145(93-119-60-68-124(273)69-61-119)189(308)260-150(101-267)193(312)244-135(52-39-84-227-202(220)221)181(300)253-143(91-117-56-64-122(271)65-57-117)187(306)243-133(50-37-82-225-200(216)217)177(296)238-128(45-25-32-77-206)174(293)246-138(71-73-153(213)275)183(302)247-139(74-86-319-18)172(291)234-113(16)168(287)263-159(106(6)7)195(314)248-131(48-28-35-80-209)176(295)239-130(47-27-34-79-208)178(297)254-144(92-118-58-66-123(272)67-59-118)188(307)251-141(88-105(4)5)185(304)235-110(13)165(284)232-112(15)167(286)264-160(107(8)9)197(316)257-140(87-104(2)3)170(289)229-99-155(277)236-127(44-24-31-76-205)173(292)240-134(51-38-83-226-201(218)219)180(299)252-142(90-116-54-62-121(270)63-55-116)186(305)242-129(46-26-33-78-207)175(294)245-137(70-72-152(212)274)182(301)241-136(53-40-85-228-203(222)223)184(303)265-161(108(10)11)196(315)249-132(49-29-36-81-210)179(298)256-147(95-154(214)276)190(309)237-126(164(215)283)43-23-30-75-204/h20-22,41-42,54-69,98,103-114,125-151,159-163,267-273H,19,23-40,43-53,70-97,99-102,204-211H2,1-18H3,(H2,212,274)(H2,213,275)(H2,214,276)(H2,215,283)(H,224,231)(H,229,289)(H,230,290)(H,232,284)(H,233,288)(H,234,291)(H,235,304)(H,236,277)(H,237,309)(H,238,296)(H,239,295)(H,240,292)(H,241,301)(H,242,305)(H,243,306)(H,244,312)(H,245,294)(H,246,293)(H,247,302)(H,248,314)(H,249,315)(H,250,285)(H,251,307)(H,252,299)(H,253,300)(H,254,297)(H,255,313)(H,256,298)(H,257,316)(H,258,317)(H,259,318)(H,260,308)(H,261,310)(H,262,278)(H,263,287)(H,264,286)(H,265,303)(H,266,311)(H,279,280)(H,281,282)(H4,216,217,225)(H4,218,219,226)(H4,220,221,227)(H4,222,223,228)/t109-,110-,111-,112-,113-,114+,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,159-,160-,161-,162-,163-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250058 (Ac-PACAP27 | CHEMBL505046) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.33,12.16,4.4,51.52,52.55,66.67,84.86,101.103,124.127,142.145,155.158,171.174,192.196,205.210,217.221,wD:20.22,2.2,40.40,58.59,72.73,90.92,113.116,133.136,150.154,162.165,180.183,200.205,210.214,(4.87,-49.9,;4.87,-51.44,;6.2,-52.21,;7.53,-51.44,;6.2,-53.75,;4.87,-54.52,;3.53,-53.75,;3.53,-52.21,;2.2,-54.52,;.87,-53.75,;-.47,-54.52,;-.47,-56.06,;-1.8,-53.75,;-1.8,-52.21,;-.47,-51.44,;.87,-52.21,;-.47,-49.9,;-3.14,-54.52,;-4.47,-53.75,;-4.47,-52.21,;-5.8,-54.52,;-5.8,-56.06,;-4.47,-56.83,;-7.14,-53.75,;-8.47,-54.52,;-8.47,-56.06,;-9.8,-53.75,;-9.8,-52.21,;-8.47,-51.44,;-7.06,-52.07,;-6.02,-50.92,;-6.8,-49.59,;-8.31,-49.91,;-11.14,-54.52,;-12.47,-53.75,;-12.47,-52.21,;-13.8,-54.52,;7.53,-54.52,;7.53,-56.06,;8.87,-53.75,;10.2,-54.52,;10.2,-56.06,;11.54,-56.83,;12.87,-56.06,;14.21,-56.83,;14.21,-58.38,;12.87,-59.15,;11.54,-58.38,;11.54,-53.75,;11.54,-52.21,;12.87,-54.52,;14.2,-53.75,;14.2,-52.21,;12.87,-51.44,;15.54,-51.44,;15.54,-54.52,;15.54,-56.06,;16.87,-53.75,;18.2,-54.52,;18.2,-56.06,;19.54,-56.83,;20.87,-56.06,;19.54,-58.37,;19.54,-53.75,;19.54,-52.21,;20.87,-54.52,;22.2,-53.75,;22.2,-52.21,;23.54,-51.44,;23.54,-54.52,;23.54,-56.06,;24.87,-53.75,;26.21,-54.52,;26.21,-56.06,;27.54,-56.83,;28.88,-56.06,;30.22,-56.83,;30.22,-58.38,;31.55,-59.15,;28.88,-59.15,;27.54,-58.38,;27.54,-53.75,;27.54,-52.21,;28.87,-54.52,;30.21,-53.75,;30.21,-52.21,;31.54,-51.44,;31.54,-54.52,;31.54,-56.06,;32.87,-53.75,;34.21,-54.52,;34.21,-56.06,;35.54,-56.83,;35.54,-58.37,;36.87,-59.14,;36.87,-60.68,;35.54,-61.45,;38.21,-61.45,;35.54,-53.75,;35.54,-52.21,;36.87,-54.52,;38.21,-53.75,;38.21,-52.21,;39.54,-51.44,;40.88,-52.22,;42.22,-51.44,;42.22,-49.9,;43.55,-49.13,;40.88,-49.13,;39.54,-49.9,;39.54,-54.52,;39.54,-56.06,;40.88,-53.75,;42.21,-54.52,;42.21,-56.06,;43.54,-56.83,;43.54,-58.37,;44.88,-59.14,;44.88,-60.68,;43.54,-61.45,;46.21,-61.45,;43.54,-53.75,;43.54,-52.21,;44.88,-54.52,;46.21,-53.75,;46.21,-52.21,;47.54,-51.44,;47.54,-49.9,;48.88,-49.13,;48.88,-47.59,;47.54,-54.52,;47.54,-56.06,;48.88,-53.75,;50.21,-54.52,;50.21,-56.06,;51.54,-56.83,;51.54,-58.37,;50.21,-59.14,;52.88,-59.14,;51.54,-53.75,;51.54,-52.21,;52.88,-54.52,;54.21,-53.75,;54.21,-52.21,;55.55,-51.44,;55.55,-49.9,;56.88,-49.13,;55.55,-54.52,;55.55,-56.06,;56.88,-53.75,;58.21,-54.52,;58.21,-56.06,;59.55,-53.75,;59.55,-52.21,;60.88,-54.52,;62.21,-53.75,;62.21,-52.21,;63.55,-51.44,;60.88,-51.44,;63.55,-54.52,;63.55,-56.06,;64.88,-53.75,;66.21,-54.52,;66.21,-56.06,;67.55,-56.83,;67.55,-58.37,;68.88,-59.14,;68.88,-60.68,;67.55,-53.75,;67.55,-52.21,;68.88,-54.52,;70.22,-53.75,;70.22,-52.21,;71.55,-51.44,;71.55,-49.9,;72.88,-49.13,;72.88,-47.59,;71.55,-54.52,;71.55,-56.06,;72.88,-53.75,;74.22,-54.52,;74.22,-56.06,;75.55,-56.83,;76.89,-56.06,;78.23,-56.83,;78.23,-58.38,;79.56,-59.15,;76.89,-59.15,;75.55,-58.38,;75.55,-53.75,;75.55,-52.21,;76.88,-54.52,;78.22,-53.75,;78.22,-52.21,;79.55,-51.44,;79.55,-49.9,;80.88,-52.21,;79.55,-54.52,;79.55,-56.06,;80.88,-53.75,;82.22,-54.52,;82.22,-56.06,;83.55,-53.75,;83.55,-52.21,;84.89,-54.52,;86.22,-53.75,;86.22,-52.21,;87.55,-54.52,;87.55,-56.06,;88.89,-53.75,;90.22,-54.52,;90.22,-56.06,;91.55,-56.83,;88.89,-56.83,;91.55,-53.75,;91.55,-52.21,;92.89,-54.52,;94.22,-53.75,;94.22,-52.21,;95.56,-51.44,;95.56,-49.9,;96.89,-52.21,;95.56,-54.52,;96.89,-53.75,;95.56,-56.06,)| Show InChI InChI=1S/C144H226N40O40S/c1-17-76(10)115(181-110(194)67-157-121(203)104(64-111(195)196)175-138(220)108(70-187)179-133(215)103(162-81(15)189)63-86-66-154-71-158-86)141(223)176-102(59-82-29-19-18-20-30-82)135(217)184-116(80(14)188)142(224)177-105(65-112(197)198)134(216)180-107(69-186)137(219)174-101(62-85-40-46-89(192)47-41-85)132(214)178-106(68-185)136(218)166-94(35-28-55-156-144(152)153)127(209)172-99(60-83-36-42-87(190)43-37-83)130(212)165-93(34-27-54-155-143(150)151)125(207)163-90(31-21-24-51-145)123(205)167-95(48-49-109(148)193)128(210)168-96(50-56-225-16)122(204)160-79(13)120(202)182-113(74(6)7)139(221)169-92(33-23-26-53-147)124(206)164-91(32-22-25-52-146)126(208)173-100(61-84-38-44-88(191)45-39-84)131(213)171-98(58-73(4)5)129(211)161-77(11)118(200)159-78(12)119(201)183-114(75(8)9)140(222)170-97(117(149)199)57-72(2)3/h18-20,29-30,36-47,66,71-80,90-108,113-116,185-188,190-192H,17,21-28,31-35,48-65,67-70,145-147H2,1-16H3,(H2,148,193)(H2,149,199)(H,154,158)(H,157,203)(H,159,200)(H,160,204)(H,161,211)(H,162,189)(H,163,207)(H,164,206)(H,165,212)(H,166,218)(H,167,205)(H,168,210)(H,169,221)(H,170,222)(H,171,213)(H,172,209)(H,173,208)(H,174,219)(H,175,220)(H,176,223)(H,177,224)(H,178,214)(H,179,215)(H,180,216)(H,181,194)(H,182,202)(H,183,201)(H,184,217)(H,195,196)(H,197,198)(H4,150,151,155)(H4,152,153,156)/t76-,77-,78-,79-,80+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,113-,114-,115-,116-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250018 (CHEMBL524852 | PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:26.26,12.16,4.4,48.49,49.52,63.64,81.83,98.100,121.124,139.142,152.155,168.171,189.193,202.207,214.218,wD:20.22,2.2,37.37,55.56,69.70,87.89,110.113,130.133,147.151,159.162,177.180,197.202,207.211,(2.22,-11.33,;2.22,-12.87,;3.55,-13.64,;4.88,-12.87,;3.55,-15.18,;2.22,-15.95,;.88,-15.18,;.88,-13.64,;-.45,-15.95,;-1.79,-15.18,;-3.12,-15.95,;-3.12,-17.49,;-4.45,-15.18,;-4.45,-13.64,;-3.12,-12.87,;-1.79,-13.64,;-3.12,-11.33,;-5.79,-15.95,;-7.12,-15.18,;-7.12,-13.64,;-8.45,-15.95,;-8.45,-17.49,;-7.12,-18.26,;-9.79,-15.18,;-11.12,-15.95,;-11.12,-17.49,;-12.45,-15.18,;-13.79,-15.95,;-12.45,-13.64,;-11.12,-12.87,;-9.71,-13.5,;-8.68,-12.35,;-9.45,-11.01,;-10.96,-11.33,;4.88,-15.95,;4.88,-17.49,;6.22,-15.18,;7.55,-15.95,;7.55,-17.49,;8.88,-18.26,;10.22,-17.49,;11.56,-18.26,;11.56,-19.8,;10.22,-20.58,;8.88,-19.8,;8.88,-15.18,;8.88,-13.64,;10.22,-15.95,;11.55,-15.18,;11.55,-13.64,;10.22,-12.87,;12.89,-12.87,;12.89,-15.95,;12.89,-17.49,;14.22,-15.18,;15.55,-15.95,;15.55,-17.49,;16.89,-18.26,;18.22,-17.49,;16.89,-19.8,;16.89,-15.18,;16.89,-13.64,;18.22,-15.95,;19.55,-15.18,;19.55,-13.64,;20.89,-12.87,;20.89,-15.95,;20.89,-17.49,;22.22,-15.18,;23.55,-15.95,;23.55,-17.49,;24.89,-18.26,;26.23,-17.49,;27.57,-18.26,;27.57,-19.8,;28.9,-20.57,;26.23,-20.58,;24.89,-19.8,;24.89,-15.18,;24.89,-13.64,;26.22,-15.95,;27.56,-15.18,;27.56,-13.64,;28.89,-12.87,;28.89,-15.95,;28.89,-17.49,;30.22,-15.18,;31.56,-15.95,;31.56,-17.49,;32.89,-18.26,;32.89,-19.8,;34.22,-20.57,;34.22,-22.11,;32.89,-22.88,;35.56,-22.88,;32.89,-15.18,;32.89,-13.64,;34.22,-15.95,;35.56,-15.18,;35.56,-13.64,;36.89,-12.87,;38.23,-13.64,;39.57,-12.87,;39.57,-11.32,;40.9,-10.55,;38.23,-10.55,;36.89,-11.32,;36.89,-15.95,;36.89,-17.49,;38.23,-15.18,;39.56,-15.95,;39.56,-17.49,;40.89,-18.26,;40.89,-19.8,;42.23,-20.57,;42.23,-22.11,;40.89,-22.88,;43.56,-22.88,;40.89,-15.18,;40.89,-13.64,;42.23,-15.95,;43.56,-15.18,;43.56,-13.64,;44.89,-12.87,;44.89,-11.33,;46.23,-10.56,;46.23,-9.02,;44.89,-15.95,;44.89,-17.49,;46.23,-15.18,;47.56,-15.95,;47.56,-17.49,;48.89,-18.26,;48.89,-19.8,;47.56,-20.57,;50.23,-20.57,;48.89,-15.18,;48.89,-13.64,;50.23,-15.95,;51.56,-15.18,;51.56,-13.64,;52.9,-12.87,;52.9,-11.33,;54.23,-10.56,;52.9,-15.95,;52.9,-17.49,;54.23,-15.18,;55.56,-15.95,;55.56,-17.49,;56.9,-15.18,;56.9,-13.64,;58.23,-15.95,;59.56,-15.18,;59.56,-13.64,;60.9,-12.87,;58.23,-12.87,;60.9,-15.95,;60.9,-17.49,;62.23,-15.18,;63.57,-15.95,;63.57,-17.49,;64.9,-18.26,;64.9,-19.8,;66.23,-20.57,;66.23,-22.11,;64.9,-15.18,;64.9,-13.64,;66.23,-15.95,;67.57,-15.18,;67.57,-13.64,;68.9,-12.87,;68.9,-11.33,;70.23,-10.56,;70.23,-9.02,;68.9,-15.95,;68.9,-17.49,;70.23,-15.18,;71.57,-15.95,;71.57,-17.49,;72.9,-18.26,;74.24,-17.49,;75.58,-18.26,;75.58,-19.8,;76.91,-20.57,;74.24,-20.58,;72.9,-19.8,;72.9,-15.18,;72.9,-13.64,;74.23,-15.95,;75.57,-15.18,;75.57,-13.64,;76.9,-12.87,;76.9,-11.33,;78.24,-13.64,;76.9,-15.95,;76.9,-17.49,;78.24,-15.18,;79.57,-15.95,;79.57,-17.49,;80.9,-15.18,;80.9,-13.64,;82.24,-15.95,;83.57,-15.18,;83.57,-13.64,;84.9,-15.95,;84.9,-17.49,;86.24,-15.18,;87.57,-15.95,;87.57,-17.49,;88.91,-18.26,;86.24,-18.26,;88.91,-15.18,;88.91,-13.64,;90.24,-15.95,;91.57,-15.18,;91.57,-13.64,;92.91,-12.87,;92.91,-11.33,;94.24,-13.64,;92.91,-15.95,;94.24,-15.18,;92.91,-17.49,)| Show InChI InChI=1S/C142H224N40O39S/c1-16-75(10)113(179-108(191)66-156-120(201)102(63-109(192)193)173-135(216)104(67-183)176-119(200)88(146)62-84-65-153-70-157-84)139(220)174-101(58-80-28-18-17-19-29-80)133(214)182-114(79(14)186)140(221)175-103(64-110(194)195)132(213)178-106(69-185)136(217)172-100(61-83-39-45-87(189)46-40-83)131(212)177-105(68-184)134(215)164-93(34-27-54-155-142(151)152)126(207)170-98(59-81-35-41-85(187)42-36-81)129(210)163-92(33-26-53-154-141(149)150)124(205)161-89(30-20-23-50-143)122(203)165-94(47-48-107(147)190)127(208)166-95(49-55-222-15)121(202)159-78(13)118(199)180-111(73(6)7)137(218)167-91(32-22-25-52-145)123(204)162-90(31-21-24-51-144)125(206)171-99(60-82-37-43-86(188)44-38-82)130(211)169-97(57-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)138(219)168-96(115(148)196)56-71(2)3/h17-19,28-29,35-46,65,70-79,88-106,111-114,183-189H,16,20-27,30-34,47-64,66-69,143-146H2,1-15H3,(H2,147,190)(H2,148,196)(H,153,157)(H,156,201)(H,158,197)(H,159,202)(H,160,209)(H,161,205)(H,162,204)(H,163,210)(H,164,215)(H,165,203)(H,166,208)(H,167,218)(H,168,219)(H,169,211)(H,170,207)(H,171,206)(H,172,217)(H,173,216)(H,174,220)(H,175,221)(H,176,200)(H,177,212)(H,178,213)(H,179,191)(H,180,199)(H,181,198)(H,182,214)(H,192,193)(H,194,195)(H4,149,150,154)(H4,151,152,155)/t75-,76-,77-,78-,79+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,111-,112-,113-,114-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250079 (CHEMBL506840 | [Pro2]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C205H333N63O52S/c1-18-111(12)164(263-158(280)102-232-171(290)149(98-159(281)282)257-195(314)153-54-40-87-268(153)201(320)126(213)96-121-100-226-105-233-121)199(318)259-147(91-116-41-20-19-21-42-116)192(311)267-165(115(16)271)200(319)260-150(99-160(283)284)191(310)262-152(104-270)194(313)255-146(95-120-61-69-125(275)70-62-120)189(308)261-151(103-269)193(312)245-136(52-38-85-229-204(222)223)181(300)253-144(93-118-57-65-123(273)66-58-118)187(306)244-134(50-36-83-227-202(218)219)177(296)239-129(45-24-31-78-208)174(293)247-139(72-74-155(215)277)183(302)248-140(75-88-321-17)172(291)235-114(15)169(288)264-161(108(6)7)196(315)249-132(48-27-34-81-211)176(295)240-131(47-26-33-80-210)178(297)254-145(94-119-59-67-124(274)68-60-119)188(307)251-142(90-107(4)5)185(304)236-112(13)167(286)234-113(14)168(287)265-162(109(8)9)198(317)258-141(89-106(2)3)170(289)231-101-157(279)237-128(44-23-30-77-207)173(292)241-135(51-37-84-228-203(220)221)180(299)252-143(92-117-55-63-122(272)64-56-117)186(305)243-130(46-25-32-79-209)175(294)246-138(71-73-154(214)276)182(301)242-137(53-39-86-230-205(224)225)184(303)266-163(110(10)11)197(316)250-133(49-28-35-82-212)179(298)256-148(97-156(216)278)190(309)238-127(166(217)285)43-22-29-76-206/h19-21,41-42,55-70,100,105-115,126-153,161-165,269-275H,18,22-40,43-54,71-99,101-104,206-213H2,1-17H3,(H2,214,276)(H2,215,277)(H2,216,278)(H2,217,285)(H,226,233)(H,231,289)(H,232,290)(H,234,286)(H,235,291)(H,236,304)(H,237,279)(H,238,309)(H,239,296)(H,240,295)(H,241,292)(H,242,301)(H,243,305)(H,244,306)(H,245,312)(H,246,294)(H,247,293)(H,248,302)(H,249,315)(H,250,316)(H,251,307)(H,252,299)(H,253,300)(H,254,297)(H,255,313)(H,256,298)(H,257,314)(H,258,317)(H,259,318)(H,260,319)(H,261,308)(H,262,310)(H,263,280)(H,264,288)(H,265,287)(H,266,303)(H,267,311)(H,281,282)(H,283,284)(H4,218,219,227)(H4,220,221,228)(H4,222,223,229)(H4,224,225,230)/t111-,112-,113-,114-,115+,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,161-,162-,163-,164-,165-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250080 (CHEMBL524495 | [Hyp2]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:20.19,12.16,4.4,50.52,51.55,65.67,83.86,100.103,123.127,141.145,154.158,170.174,191.196,204.210,216.221,wD:2.2,39.40,57.59,71.73,89.92,112.116,132.136,149.154,161.165,179.183,199.205,209.214,22.22,28.29,(.66,6.05,;.66,4.51,;1.99,3.74,;3.32,4.51,;1.99,2.2,;.66,1.43,;-.68,2.2,;-.68,3.74,;-2.01,1.43,;-3.35,2.2,;-4.68,1.43,;-4.68,-.11,;-6.01,2.2,;-6.01,3.74,;-4.68,4.51,;-3.35,3.74,;-4.68,6.05,;-7.35,1.43,;-8.68,2.2,;-8.68,3.74,;-10.01,1.43,;-11.43,2.06,;-12.46,.91,;-13.99,1.07,;-11.69,-.42,;-10.18,-.1,;-9.04,-1.13,;-7.58,-.66,;-9.36,-2.64,;-10.83,-3.11,;-8.22,-3.67,;-8.55,-5.18,;-9.96,-5.81,;-9.8,-7.34,;-8.3,-7.67,;-7.53,-6.33,;3.32,1.43,;3.32,-.11,;4.66,2.2,;5.99,1.43,;5.99,-.11,;7.32,-.88,;8.66,-.1,;10,-.88,;10,-2.42,;8.66,-3.19,;7.32,-2.42,;7.32,2.2,;7.32,3.74,;8.66,1.43,;9.99,2.2,;9.99,3.74,;8.66,4.51,;11.32,4.51,;11.32,1.43,;11.32,-.11,;12.66,2.2,;13.99,1.43,;13.99,-.11,;15.33,-.88,;16.66,-.11,;15.33,-2.42,;15.33,2.2,;15.33,3.74,;16.66,1.43,;17.99,2.2,;17.99,3.74,;19.33,4.51,;19.33,1.43,;19.33,-.11,;20.66,2.2,;21.99,1.43,;21.99,-.11,;23.33,-.88,;24.67,-.1,;26,-.88,;26,-2.42,;27.34,-3.19,;24.67,-3.19,;23.33,-2.42,;23.33,2.2,;23.33,3.74,;24.66,1.43,;26,2.2,;26,3.74,;27.33,4.51,;27.33,1.43,;27.33,-.11,;28.66,2.2,;30,1.43,;30,-.11,;31.33,-.88,;31.33,-2.42,;32.66,-3.19,;32.66,-4.73,;31.33,-5.5,;34,-5.5,;31.33,2.2,;31.33,3.74,;32.66,1.43,;34,2.2,;34,3.74,;35.33,4.51,;36.67,3.74,;38.01,4.51,;38.01,6.06,;39.34,6.83,;36.67,6.83,;35.33,6.06,;35.33,1.43,;35.33,-.11,;36.66,2.2,;38,1.43,;38,-.11,;39.33,-.88,;39.33,-2.42,;40.67,-3.19,;40.67,-4.73,;39.33,-5.5,;42,-5.5,;39.33,2.2,;39.33,3.74,;40.67,1.43,;42,2.2,;42,3.74,;43.33,4.51,;43.33,6.05,;44.67,6.82,;44.67,8.36,;43.33,1.43,;43.33,-.11,;44.67,2.2,;46,1.43,;46,-.11,;47.33,-.88,;47.33,-2.42,;46,-3.19,;48.67,-3.19,;47.33,2.2,;47.33,3.74,;48.67,1.43,;50,2.2,;50,3.74,;51.34,4.51,;51.34,6.05,;52.67,6.82,;51.34,1.43,;51.34,-.11,;52.67,2.2,;54,1.43,;54,-.11,;55.34,2.2,;55.34,3.74,;56.67,1.43,;58,2.2,;58,3.74,;59.34,4.51,;56.67,4.51,;59.34,1.43,;59.34,-.11,;60.67,2.2,;62,1.43,;62,-.11,;63.34,-.88,;63.34,-2.42,;64.67,-3.19,;64.67,-4.73,;63.34,2.2,;63.34,3.74,;64.67,1.43,;66.01,2.2,;66.01,3.74,;67.34,4.51,;67.34,6.05,;68.67,6.82,;68.67,8.36,;67.34,1.43,;67.34,-.11,;68.67,2.2,;70.01,1.43,;70.01,-.11,;71.34,-.88,;72.68,-.1,;74.02,-.88,;74.02,-2.42,;75.35,-3.19,;72.68,-3.19,;71.34,-2.42,;71.34,2.2,;71.34,3.74,;72.67,1.43,;74.01,2.2,;74.01,3.74,;75.34,4.51,;75.34,6.05,;76.67,3.74,;75.34,1.43,;75.34,-.11,;76.67,2.2,;78.01,1.43,;78.01,-.11,;79.34,2.2,;79.34,3.74,;80.68,1.43,;82.01,2.2,;82.01,3.74,;83.34,1.43,;83.34,-.11,;84.68,2.2,;86.01,1.43,;86.01,-.11,;87.34,-.88,;84.68,-.88,;87.34,2.2,;87.34,3.74,;88.68,1.43,;90.01,2.2,;90.01,3.74,;91.35,4.51,;91.35,6.05,;92.68,3.74,;91.35,1.43,;92.68,2.2,;91.35,-.11,)| Show InChI InChI=1S/C144H226N40O39S/c1-16-76(10)115(180-110(193)67-158-121(202)104(64-111(194)195)175-137(218)108-63-89(191)68-184(108)142(223)90(148)62-85-66-155-71-159-85)140(221)176-103(58-81-28-18-17-19-29-81)134(215)183-116(80(14)187)141(222)177-105(65-112(196)197)133(214)179-107(70-186)136(217)174-102(61-84-39-45-88(190)46-40-84)132(213)178-106(69-185)135(216)166-95(34-27-54-157-144(153)154)127(208)172-100(59-82-35-41-86(188)42-36-82)130(211)165-94(33-26-53-156-143(151)152)125(206)163-91(30-20-23-50-145)123(204)167-96(47-48-109(149)192)128(209)168-97(49-55-224-15)122(203)161-79(13)120(201)181-113(74(6)7)138(219)169-93(32-22-25-52-147)124(205)164-92(31-21-24-51-146)126(207)173-101(60-83-37-43-87(189)44-38-83)131(212)171-99(57-73(4)5)129(210)162-77(11)118(199)160-78(12)119(200)182-114(75(8)9)139(220)170-98(117(150)198)56-72(2)3/h17-19,28-29,35-46,66,71-80,89-108,113-116,185-191H,16,20-27,30-34,47-65,67-70,145-148H2,1-15H3,(H2,149,192)(H2,150,198)(H,155,159)(H,158,202)(H,160,199)(H,161,203)(H,162,210)(H,163,206)(H,164,205)(H,165,211)(H,166,216)(H,167,204)(H,168,209)(H,169,219)(H,170,220)(H,171,212)(H,172,208)(H,173,207)(H,174,217)(H,175,218)(H,176,221)(H,177,222)(H,178,213)(H,179,214)(H,180,193)(H,181,201)(H,182,200)(H,183,215)(H,194,195)(H,196,197)(H4,151,152,156)(H4,153,154,157)/t76-,77-,78-,79-,80+,89+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,113-,114-,115-,116-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250081 (CHEMBL499507 | [Hyp2]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C205H333N63O53S/c1-18-110(12)164(263-158(281)100-232-171(291)149(96-159(282)283)257-195(315)153-94-125(276)101-268(153)201(321)126(213)93-120-98-226-104-233-120)199(319)259-147(88-115-40-20-19-21-41-115)192(312)267-165(114(16)271)200(320)260-150(97-160(284)285)191(311)262-152(103-270)194(314)255-146(92-119-59-67-124(275)68-60-119)189(309)261-151(102-269)193(313)245-136(51-38-83-229-204(222)223)181(301)253-144(90-117-55-63-122(273)64-56-117)187(307)244-134(49-36-81-227-202(218)219)177(297)239-129(44-24-31-76-208)174(294)247-139(70-72-155(215)278)183(303)248-140(73-85-322-17)172(292)235-113(15)169(289)264-161(107(6)7)196(316)249-132(47-27-34-79-211)176(296)240-131(46-26-33-78-210)178(298)254-145(91-118-57-65-123(274)66-58-118)188(308)251-142(87-106(4)5)185(305)236-111(13)167(287)234-112(14)168(288)265-162(108(8)9)198(318)258-141(86-105(2)3)170(290)231-99-157(280)237-128(43-23-30-75-207)173(293)241-135(50-37-82-228-203(220)221)180(300)252-143(89-116-53-61-121(272)62-54-116)186(306)243-130(45-25-32-77-209)175(295)246-138(69-71-154(214)277)182(302)242-137(52-39-84-230-205(224)225)184(304)266-163(109(10)11)197(317)250-133(48-28-35-80-212)179(299)256-148(95-156(216)279)190(310)238-127(166(217)286)42-22-29-74-206/h19-21,40-41,53-68,98,104-114,125-153,161-165,269-276H,18,22-39,42-52,69-97,99-103,206-213H2,1-17H3,(H2,214,277)(H2,215,278)(H2,216,279)(H2,217,286)(H,226,233)(H,231,290)(H,232,291)(H,234,287)(H,235,292)(H,236,305)(H,237,280)(H,238,310)(H,239,297)(H,240,296)(H,241,293)(H,242,302)(H,243,306)(H,244,307)(H,245,313)(H,246,295)(H,247,294)(H,248,303)(H,249,316)(H,250,317)(H,251,308)(H,252,300)(H,253,301)(H,254,298)(H,255,314)(H,256,299)(H,257,315)(H,258,318)(H,259,319)(H,260,320)(H,261,309)(H,262,311)(H,263,281)(H,264,289)(H,265,288)(H,266,304)(H,267,312)(H,282,283)(H,284,285)(H4,218,219,227)(H4,220,221,228)(H4,222,223,229)(H4,224,225,230)/t110-,111-,112-,113-,114+,125+,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,161-,162-,163-,164-,165-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250026 (CHEMBL526899 | [Ala4]PACAP27) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O |r,wU:27.27,13.17,4.4,49.50,50.53,64.65,82.84,99.101,122.125,140.143,153.156,169.172,190.194,203.208,215.219,wD:21.23,2.2,38.38,56.57,70.71,88.90,111.114,131.134,148.152,160.163,178.181,198.203,208.212,8.8,(2.3,.71,;2.3,-.83,;3.64,-1.6,;4.97,-.83,;3.64,-3.14,;2.3,-3.91,;.97,-3.14,;.97,-1.6,;-.37,-3.91,;-.37,-5.45,;-1.7,-3.14,;-3.03,-3.91,;-3.03,-5.45,;-4.37,-3.14,;-4.37,-1.6,;-3.03,-.83,;-1.7,-1.6,;-3.03,.71,;-5.7,-3.91,;-7.03,-3.14,;-7.03,-1.6,;-8.37,-3.91,;-8.37,-5.45,;-7.03,-6.22,;-9.7,-3.14,;-11.03,-3.91,;-11.03,-5.45,;-12.37,-3.14,;-13.7,-3.91,;-12.37,-1.6,;-11.03,-.83,;-9.62,-1.46,;-8.59,-.31,;-9.36,1.02,;-10.87,.7,;4.97,-3.91,;4.97,-5.45,;6.3,-3.14,;7.64,-3.91,;7.64,-5.45,;8.97,-6.22,;10.31,-5.45,;11.65,-6.22,;11.65,-7.77,;10.31,-8.54,;8.97,-7.77,;8.97,-3.14,;8.97,-1.6,;10.3,-3.91,;11.64,-3.14,;11.64,-1.6,;10.3,-.83,;12.97,-.83,;12.97,-3.91,;12.97,-5.45,;14.31,-3.14,;15.64,-3.91,;15.64,-5.45,;16.97,-6.22,;18.31,-5.45,;16.97,-7.76,;16.97,-3.14,;16.97,-1.6,;18.31,-3.91,;19.64,-3.14,;19.64,-1.6,;20.97,-.83,;20.97,-3.91,;20.97,-5.45,;22.31,-3.14,;23.64,-3.91,;23.64,-5.45,;24.97,-6.22,;26.31,-5.45,;27.65,-6.22,;27.65,-7.77,;28.98,-8.54,;26.31,-8.54,;24.97,-7.77,;24.97,-3.14,;24.97,-1.6,;26.31,-3.91,;27.64,-3.14,;27.64,-1.6,;28.98,-.83,;28.98,-3.91,;28.98,-5.45,;30.31,-3.14,;31.64,-3.91,;31.64,-5.45,;32.98,-6.22,;32.98,-7.76,;34.31,-8.53,;34.31,-10.07,;32.98,-10.84,;35.64,-10.84,;32.98,-3.14,;32.98,-1.6,;34.31,-3.91,;35.64,-3.14,;35.64,-1.6,;36.98,-.83,;38.32,-1.61,;39.65,-.83,;39.65,.71,;40.99,1.48,;38.32,1.48,;36.98,.71,;36.98,-3.91,;36.98,-5.45,;38.31,-3.14,;39.64,-3.91,;39.64,-5.45,;40.98,-6.22,;40.98,-7.76,;42.31,-8.53,;42.31,-10.07,;40.98,-10.84,;43.65,-10.84,;40.98,-3.14,;40.98,-1.6,;42.31,-3.91,;43.65,-3.14,;43.65,-1.6,;44.98,-.83,;44.98,.71,;46.31,1.48,;46.31,3.02,;44.98,-3.91,;44.98,-5.45,;46.31,-3.14,;47.65,-3.91,;47.65,-5.45,;48.98,-6.22,;48.98,-7.76,;47.65,-8.53,;50.31,-8.53,;48.98,-3.14,;48.98,-1.6,;50.31,-3.91,;51.65,-3.14,;51.65,-1.6,;52.98,-.83,;52.98,.71,;54.31,1.48,;52.98,-3.91,;52.98,-5.45,;54.31,-3.14,;55.65,-3.91,;55.65,-5.45,;56.98,-3.14,;56.98,-1.6,;58.32,-3.91,;59.65,-3.14,;59.65,-1.6,;60.98,-.83,;58.32,-.83,;60.98,-3.91,;60.98,-5.45,;62.32,-3.14,;63.65,-3.91,;63.65,-5.45,;64.98,-6.22,;64.98,-7.76,;66.32,-8.53,;66.32,-10.07,;64.98,-3.14,;64.98,-1.6,;66.32,-3.91,;67.65,-3.14,;67.65,-1.6,;68.98,-.83,;68.98,.71,;70.32,1.48,;70.32,3.02,;68.98,-3.91,;68.98,-5.45,;70.32,-3.14,;71.65,-3.91,;71.65,-5.45,;72.99,-6.22,;74.32,-5.45,;75.66,-6.22,;75.66,-7.77,;77,-8.54,;74.32,-8.54,;72.99,-7.77,;72.99,-3.14,;72.99,-1.6,;74.32,-3.91,;75.65,-3.14,;75.65,-1.6,;76.99,-.83,;76.99,.71,;78.32,-1.6,;76.99,-3.91,;76.99,-5.45,;78.32,-3.14,;79.65,-3.91,;79.65,-5.45,;80.99,-3.14,;80.99,-1.6,;82.32,-3.91,;83.66,-3.14,;83.66,-1.6,;84.99,-3.91,;84.99,-5.45,;86.32,-3.14,;87.66,-3.91,;87.66,-5.45,;88.99,-6.22,;86.32,-6.22,;88.99,-3.14,;88.99,-1.6,;90.32,-3.91,;91.66,-3.14,;91.66,-1.6,;92.99,-.83,;92.99,.71,;94.32,-1.6,;92.99,-3.91,;94.32,-3.14,;92.99,-5.45,)| Show InChI InChI=1S/C143H226N40O39S/c1-17-75(10)113(182-119(200)79(14)161-129(210)103(64-109(192)193)174-136(217)105(67-184)177-120(201)89(147)63-85-66-154-70-157-85)140(221)175-102(59-81-29-19-18-20-30-81)134(215)183-114(80(15)187)141(222)176-104(65-110(194)195)133(214)179-107(69-186)137(218)173-101(62-84-40-46-88(190)47-41-84)132(213)178-106(68-185)135(216)165-94(35-28-55-156-143(152)153)126(207)171-99(60-82-36-42-86(188)43-37-82)130(211)164-93(34-27-54-155-142(150)151)124(205)162-90(31-21-24-51-144)122(203)166-95(48-49-108(148)191)127(208)167-96(50-56-223-16)121(202)159-78(13)118(199)180-111(73(6)7)138(219)168-92(33-23-26-53-146)123(204)163-91(32-22-25-52-145)125(206)172-100(61-83-38-44-87(189)45-39-83)131(212)170-98(58-72(4)5)128(209)160-76(11)116(197)158-77(12)117(198)181-112(74(8)9)139(220)169-97(115(149)196)57-71(2)3/h18-20,29-30,36-47,66,70-80,89-107,111-114,184-190H,17,21-28,31-35,48-65,67-69,144-147H2,1-16H3,(H2,148,191)(H2,149,196)(H,154,157)(H,158,197)(H,159,202)(H,160,209)(H,161,210)(H,162,205)(H,163,204)(H,164,211)(H,165,216)(H,166,203)(H,167,208)(H,168,219)(H,169,220)(H,170,212)(H,171,207)(H,172,206)(H,173,218)(H,174,217)(H,175,221)(H,176,222)(H,177,201)(H,178,213)(H,179,214)(H,180,199)(H,181,198)(H,182,200)(H,183,215)(H,192,193)(H,194,195)(H4,150,151,155)(H4,152,153,156)/t75-,76-,77-,78-,79-,80+,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,111-,112-,113-,114-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor (Homo sapiens (Human))	BDBM50250047 (CHEMBL525591 | [N-Me-Ser2]PACAP38) Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)N(C)C(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C204H333N63O53S/c1-19-110(12)163(262-157(280)100-231-170(290)148(96-158(281)282)256-194(314)152(103-270)267(17)200(320)125(212)94-120-98-225-104-232-120)198(318)258-146(89-115-41-21-20-22-42-115)191(311)266-164(114(16)271)199(319)259-149(97-159(283)284)190(310)261-151(102-269)193(313)254-145(93-119-60-68-124(275)69-61-119)188(308)260-150(101-268)192(312)244-135(52-39-84-228-203(221)222)180(300)252-143(91-117-56-64-122(273)65-57-117)186(306)243-133(50-37-82-226-201(217)218)176(296)238-128(45-25-32-77-207)173(293)246-138(71-73-154(214)277)182(302)247-139(74-86-321-18)171(291)234-113(15)168(288)263-160(107(6)7)195(315)248-131(48-28-35-80-210)175(295)239-130(47-27-34-79-209)177(297)253-144(92-118-58-66-123(274)67-59-118)187(307)250-141(88-106(4)5)184(304)235-111(13)166(286)233-112(14)167(287)264-161(108(8)9)197(317)257-140(87-105(2)3)169(289)230-99-156(279)236-127(44-24-31-76-206)172(292)240-134(51-38-83-227-202(219)220)179(299)251-142(90-116-54-62-121(272)63-55-116)185(305)242-129(46-26-33-78-208)174(294)245-137(70-72-153(213)276)181(301)241-136(53-40-85-229-204(223)224)183(303)265-162(109(10)11)196(316)249-132(49-29-36-81-211)178(298)255-147(95-155(215)278)189(309)237-126(165(216)285)43-23-30-75-205/h20-22,41-42,54-69,98,104-114,125-152,160-164,268-275H,19,23-40,43-53,70-97,99-103,205-212H2,1-18H3,(H2,213,276)(H2,214,277)(H2,215,278)(H2,216,285)(H,225,232)(H,230,289)(H,231,290)(H,233,286)(H,234,291)(H,235,304)(H,236,279)(H,237,309)(H,238,296)(H,239,295)(H,240,292)(H,241,301)(H,242,305)(H,243,306)(H,244,312)(H,245,294)(H,246,293)(H,247,302)(H,248,315)(H,249,316)(H,250,307)(H,251,299)(H,252,300)(H,253,297)(H,254,313)(H,255,298)(H,256,314)(H,257,317)(H,258,318)(H,259,319)(H,260,308)(H,261,310)(H,262,280)(H,263,288)(H,264,287)(H,265,303)(H,266,311)(H,281,282)(H,283,284)(H4,217,218,226)(H4,219,220,227)(H4,221,222,228)(H4,223,224,229)/t110-,111-,112-,113-,114+,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,160-,161-,162-,163-,164-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut National de la Recherche Scientifique Curated by ChEMBL					Assay Description Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counter				J Med Chem 52: 3308-16 (2009) Article DOI: 10.1021/jm900291j BindingDB Entry DOI: 10.7270/Q29023PC
					More data for this Ligand-Target Pair

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