BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Calcium-activated potassium channel subunit beta-1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Calcium-activated potassium channel subunit beta-1 (RAT)	BDBM84745 (CAS_136434-34-9 \| DULOXETINE \| LY-248686 \| LY24868...) Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by PDSP K_i Database									Neuropsychopharmacology 25: 871-80 (2001) Article DOI: 10.1016/S0893-133X(01)00298-6 BindingDB Entry DOI: 10.7270/Q25M648W
Lilly Research Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta-1 (Homo sapiens (Human))	BDBM50171290 (5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Synthelabo Recherche Curated by PDSP K_i Database									J Pharmacol Exp Ther 310: 905-14 (2004) Article DOI: 10.1124/jpet.104.067884 BindingDB Entry DOI: 10.7270/Q2RR1WTX
Sanofi-Synthelabo Recherche Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta-1 (RAT)	BDBM82071 (CAS_93413-69-5 \| CAS_99300-78-4 \| NSC_62923 \| VENL...) Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by PDSP K_i Database									Neuropsychopharmacology 25: 871-80 (2001) Article DOI: 10.1016/S0893-133X(01)00298-6 BindingDB Entry DOI: 10.7270/Q25M648W
Lilly Research Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta-1 (RAT)	BDBM50094703 (5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP K_i Database									J Pharmacol Exp Ther 295: 1156-64 (2000) BindingDB Entry DOI: 10.7270/Q2DF6PSP
Abbott Laboratories Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta-1 (Homo sapiens (Human))	BDBM21280 (5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)met...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Recherche Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 644-50 (1998) BindingDB Entry DOI: 10.7270/Q2D50KHT
Sanofi Recherche Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Calcium-activated potassium channel subunit beta-1 (Homo sapiens (Human))	BDBM50557680 (CHEMBL4741793) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BK (unknown origin) by patch clamp analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00675 BindingDB Entry DOI: 10.7270/Q2QF8XJ0
TBA					More data for this Ligand-Target Pair