Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263346 (US9546162, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.300 | n/a | n/a | n/a | 11 | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description Cells were seeded at a density of 5×104 cells per well in Biocoat® Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) an... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179992 (US9676720, Example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179995 (US9676720, Example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | CHEMBL5285583 | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL CHEMBL PC cid PC sid UniChem Similars | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonist activity at NK-2 tachykinin receptors in rabbit pulmonary artery | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50101830 ((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Compound was evaluated for its competitive binding affinity towards human Prostanoid EP2 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180045 (US9676720, Comparative example 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179994 (US9676720, Example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179998 (US9676720, Example 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179996 (US9676720, Example 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179993 (US9676720, Example 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180000 (US9676720, Example 14) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179999 (US9676720, Example 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180002 (US9676720, Example 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179997 (US9676720, Example 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.970 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180003 (US9676720, Example 18) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.990 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM35847 ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cayman Chemical Company, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho... | J Med Chem 62: 4731-4741 (2019) Article DOI: 10.1021/acs.jmedchem.9b00336 BindingDB Entry DOI: 10.7270/Q22R3W32 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180020 (US9676720, Comparative example 8) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119438 (BDBM119693 | US8685986, 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.10 | -52.0 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180024 (US9676720, Comparative example 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180019 (US9676720, Comparative example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180004 (US9676720, Example 19) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180021 (US9676720, Comparative example 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180005 (US9676720, Comparative example 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50385141 (CHEMBL2036321) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119442 (US8685986, 17) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.5 | -51.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50366137 (CHEMBL1957436) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50366137 (CHEMBL1957436) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50016952 (CHEMBL3286796) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to EP2 receptor (unknown origin) by competitive binding assay | J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180022 (US9676720, Comparative example 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119432 (US8685986, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.90 | -50.6 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180025 (US9676720, Comparative example 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263347 (US9546162, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2 | n/a | n/a | n/a | 11 | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50385128 (CHEMBL2036318) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263343 (US9546162, 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50385131 (CHEMBL2036322) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50101830 ((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Binding affinity towards mouse Prostanoid EP2 receptor expressed in CHO cells. | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180018 (US9676720, Comparative example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180026 (US9676720, Comparative example 13) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119433 (US8685986, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.80 | -49.6 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263357 (US9546162, 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3 | n/a | n/a | n/a | 11 | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50366136 (CHEMBL1957435) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 3502-22 (2012) Article DOI: 10.1016/j.bmc.2012.04.008 BindingDB Entry DOI: 10.7270/Q2D50P0B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50366136 (CHEMBL1957435) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50360628 (CHEMBL1933724) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting | Bioorg Med Chem 20: 2235-51 (2012) Article DOI: 10.1016/j.bmc.2012.02.018 BindingDB Entry DOI: 10.7270/Q2542P2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse)) | BDBM50360628 (CHEMBL1933724) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 22: 396-401 (2011) Article DOI: 10.1016/j.bmcl.2011.10.109 BindingDB Entry DOI: 10.7270/Q27P8ZT2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119441 (US8685986, 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.10 | -49.4 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180038 (US9676720, Comparative example 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50101830 ((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to EP2 receptor (unknown origin) by competitive binding assay | J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50506546 (Omidenepag | UR-7276) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180006 (US9676720, Comparative example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119437 (US8685986, 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.80 | -48.9 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 1845 total ) | Next | Last >> |