Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'RCG21202'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RCG21202 (Rattus norvegicus)	BDBM50391825 (CHEMBL2146910) Show SMILES OC(=O)c1cc(O)cc(Cl)c1 Show InChI InChI=1S/C7H5ClO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,(H,10,11)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at rat GPR81				ACS Med Chem Lett 3: 637-639 (2012) Article DOI: 10.1021/ml3000676 BindingDB Entry DOI: 10.7270/Q27945RB
					More data for this Ligand-Target Pair
RCG21202 (Rattus norvegicus)	BDBM50462128 (CHEMBL4248415) Show SMILES [#6]-[#6]-[#8]-c1cc(Cl)c(cc1-[#7]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6](=O)-[#7]-c1nc2-[#6]-[#6][Si;v4]([#6])([#6]-c2s1)c1c(-[#8]-[#6])cccc1-[#8]-[#6] Show InChI InChI=1S/C29H35ClN4O6SSi/c1-5-40-24-16-19(30)18(15-21(24)34-10-12-39-13-11-34)27(35)32-28(36)33-29-31-20-9-14-42(4,17-25(20)41-29)26-22(37-2)7-6-8-23(26)38-3/h6-8,15-16H,5,9-14,17H2,1-4H3,(H2,31,32,33,35,36)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
CSIR-National Chemical Laboratory Curated by ChEMBL					Assay Description Agonist activity at rat GPR81 expressed in T-REx-CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 30 mins ...				J Med Chem 61: 3779-3798 (2018) Article DOI: 10.1021/acs.jmedchem.7b00718 BindingDB Entry DOI: 10.7270/Q2GT5QTK
					More data for this Ligand-Target Pair
RCG21202 (Rattus norvegicus)	BDBM50462127 (CHEMBL4239086) Show SMILES CCOc1cc(Cl)c(cc1N1CCOCC1)C(=O)NC(=O)Nc1nc2CCCCc2s1 Show InChI InChI=1S/C21H25ClN4O4S/c1-2-30-17-12-14(22)13(11-16(17)26-7-9-29-10-8-26)19(27)24-20(28)25-21-23-15-5-3-4-6-18(15)31-21/h11-12H,2-10H2,1H3,(H2,23,24,25,27,28)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
CSIR-National Chemical Laboratory Curated by ChEMBL					Assay Description Agonist activity at rat GPR81 expressed in T-REx-CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 30 mins ...				J Med Chem 61: 3779-3798 (2018) Article DOI: 10.1021/acs.jmedchem.7b00718 BindingDB Entry DOI: 10.7270/Q2GT5QTK
					More data for this Ligand-Target Pair
RCG21202 (Rattus norvegicus)	BDBM50462122 (CHEMBL4240407) Show SMILES [#6]-[#6]-[#8]-c1cc(Cl)c(cc1-[#7]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6](=O)-[#7]-c1nc2-[#6]-[#6][Si;v4]([#6])([#6]-c2s1)c1ccc(-[#8]-[#6])cc1 Show InChI InChI=1S/C28H33ClN4O5SSi/c1-4-38-24-16-21(29)20(15-23(24)33-10-12-37-13-11-33)26(34)31-27(35)32-28-30-22-9-14-40(3,17-25(22)39-28)19-7-5-18(36-2)6-8-19/h5-8,15-16H,4,9-14,17H2,1-3H3,(H2,30,31,32,34,35)	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
CSIR-National Chemical Laboratory Curated by ChEMBL					Assay Description Agonist activity at rat GPR81 expressed in T-REx-CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 30 mins ...				J Med Chem 61: 3779-3798 (2018) Article DOI: 10.1021/acs.jmedchem.7b00718 BindingDB Entry DOI: 10.7270/Q2GT5QTK
					More data for this Ligand-Target Pair