Compile Data Set for Download or QSAR

Found 158 hits Enz. Inhib. hit(s) with Target = 'Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646432 (US11878973, Example 37) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(c(F)c1C)C(F)(F)F)C1=CCOCC1 |t:49| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646438 (US11878973, Example 40) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(F)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646458 (US11878973, Example 50) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncnc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1cc(F)c(cc1C)C(F)(F)F)C1=CCOCC1 |t:49| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646369 (US11878973, Example 13) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1cc(Cl)c(cc1C)C(F)(F)F)N1CCCC(F)C1 Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646481 (N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-d...) Show SMILES CCc1c(N2CCN([C@H]3CC[C@H]23)C(=O)c2ncnc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCOCC1 |r,t:51| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646462 (US11878973, Example 52) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncncc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)S(F)(F)(F)(F)F)C1=CCOCC1 |t:49| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646465 (US11878973, Example 117) Show SMILES Cc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CCOCC1 |t:45| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646351 (US11878973, Example 4) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1cc(Cl)c(cc1C)C(F)(F)F)N1CCOCC1 Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646356 (US11878973, Example 66) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646362 (US11878973, Example 69) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1cc(Cl)c(cc1C)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646383 (US11878973, Example 79) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(c(F)c1C)C(F)(F)F)C1=COCCO1 |t:49| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646391 (US11878973, Example 81a) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CC[C@@H](CC1)OC |r,t:46| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646393 (US11878973, Example 81b) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CCC(CC1)OC |t:46| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646409 (US11878973, Example 89) Show SMILES C[C@@H]1CN(CCN1C(=O)c1ncccc1O)c1c(C)n(CC(=O)Nc2ccc(cc2)C(F)(F)F)c2nc(nn2c1=O)C1=CCOCC1 |r,t:46| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646419 (US11878973, Example 94) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1cc(F)c(cc1C)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646427 (US11878973, Example 98) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(OC(F)(F)F)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCOCC1 |t:52| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646434 (US11878973, Example 38) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(c(F)c1C)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646436 (US11878973, Example 39) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646440 (US11878973, Example 41) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nc(C)cc(F)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCOCC1 |t:49| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646457 (US11878973, Example 113) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)C1=COCCO1 |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646460 (US11878973, Example 51) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncnc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)S(F)(F)(F)(F)F)C1=CCOCC1 |t:50| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646368 (US11878973, Example 72) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CCOCC1 |t:46| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646421 (US11878973, Example 95) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1cc(F)c(cc1C)C(F)(F)F)C1=CCOCC1 |t:49| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646345 (US11878973, Example 1) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)N1CCOCC1 Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646415 (US11878973, Example 92) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1F)C(F)(F)F)C1=CCOCC1 |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646489 (N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-d...) Show SMILES CCc1c(N2CCN(CC2)S(=O)(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646399 (US11878973, Example 84) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CCCCO1 |t:46| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646374 (US11878973, Example 75) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CCOCC1 |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646372 (US11878973, Example 74) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nc(C)ccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CCOCC1 |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646354 (US11878973, Example 65) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncc(Cl)cc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646348 (US11878973, Example 62) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nc(C)cc(F)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)C1=CCOCC1 |t:49| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646346 (US11878973, Example 61) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646445 (US11878973, Example 107) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncnc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1F)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646423 (US11878973, Example 96) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCOCC1 |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	MCE PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646463 (US11878973, Example 116) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1cc(F)c(cc1Cl)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646483 (US11878973, Example 134) Show SMILES Oc1cccnc1C(=O)N1CCN(CC1)c1c(C2CC2)n(CC(=O)Nc2ccc(cc2)C(F)(F)F)c2nc(nn2c1=O)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646474 (US11878973, Example 58) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)C1=CCOCC1 |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	MCE PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646361 (US11878973, Example 9) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)N1CCOCC1 Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646385 (US11878973, Example 80 | US11878973, Example 80b) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)C1=CCC(CC1)OC |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646431 (US11878973, Example 100) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncnc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)S(F)(F)(F)(F)F)C1=CCOCC1 |t:50| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646422 (US11878973, Example 32) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCCCO1 |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646443 (US11878973, Example 106) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncnc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(Br)cc1Cl)C1=CCOCC1 |t:45| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646349 (US11878973, Example 3) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(F)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)N1CCOCC1 Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646366 (US11878973, Example 71) Show SMILES CCc1c(N2CCN([C@H](C)C2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CCOCC1 |r,t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646387 (US11878973, Example 80a) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncccc2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)C1=CC[C@@H](CC1)OC |r,t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646454 (US11878973, Example 48) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(F)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(nc1Cl)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646401 (US11878973, Example 85) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1C)C(F)(F)F)N1CCC[C@H](F)C1 |r| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646355 (US11878973, Example 6) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(Cl)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1cc(F)c(cc1C)C(F)(F)F)N1CCOCC1 Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646442 (US11878973, Example 123 | US11878973, Example 133 ...) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncnc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1Cl)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	MCE PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646370 (US11878973, Example 73) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2ncnc(C)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(cc1)C(F)(F)F)C1=CCOCC1 |t:47| Show InChI	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

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