Compile Data Set for Download or QSAR

Found 61 hits Enz. Inhib. hit(s) with Target = 'DNA-directed RNA polymerase subunit alpha'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466524 (US10800725, Compound 12) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(cc2)C(F)(F)F)=C1O |c:5,36| Show InChI InChI=1S/C31H43F3O4/c1-19(2)7-13-24-27(36)26(25(35)14-10-22-8-11-23(12-9-22)31(32,33)34)29(38)30(28(24)37,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,36-37H,7,10,13-18H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466519 (US10800725, Compound 7) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2C)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)12-14-25-28(33)27(26(32)15-13-24-11-9-8-10-23(24)7)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h8-11,20-22,33-34H,12-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466519 (US10800725, Compound 7) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2C)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)12-14-25-28(33)27(26(32)15-13-24-11-9-8-10-23(24)7)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h8-11,20-22,33-34H,12-19H2,1-7H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466521 (US10800725, Compound 9) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(C)cc2)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)8-14-25-28(33)27(26(32)15-13-24-11-9-23(7)10-12-24)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h9-12,20-22,33-34H,8,13-19H2,1-7H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466524 (US10800725, Compound 12) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(cc2)C(F)(F)F)=C1O |c:5,36| Show InChI InChI=1S/C31H43F3O4/c1-19(2)7-13-24-27(36)26(25(35)14-10-22-8-11-23(12-9-22)31(32,33)34)29(38)30(28(24)37,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,36-37H,7,10,13-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466521 (US10800725, Compound 9) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(C)cc2)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)8-14-25-28(33)27(26(32)15-13-24-11-9-23(7)10-12-24)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h9-12,20-22,33-34H,8,13-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466520 (US10800725, Compound 8) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2cccc(C)c2)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)11-13-25-28(33)27(26(32)14-12-24-10-8-9-23(7)19-24)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-10,19-22,33-34H,11-18H2,1-7H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466524 (US10800725, Compound 12) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(cc2)C(F)(F)F)=C1O |c:5,36| Show InChI InChI=1S/C31H43F3O4/c1-19(2)7-13-24-27(36)26(25(35)14-10-22-8-11-23(12-9-22)31(32,33)34)29(38)30(28(24)37,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,36-37H,7,10,13-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466522 (US10800725, Compound 10) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(F)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43FO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466520 (US10800725, Compound 8) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2cccc(C)c2)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)11-13-25-28(33)27(26(32)14-12-24-10-8-9-23(7)19-24)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-10,19-22,33-34H,11-18H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466515 (US10800725, Compound 3) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466522 (US10800725, Compound 10) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(F)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43FO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466526 (US10800725, Compound 14) Show SMILES CCCCC1=C(O)C(CCCC)(CCCC)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:4,30| Show InChI InChI=1S/C27H37ClO4/c1-4-7-10-21-24(30)23(22(29)16-13-19-11-14-20(28)15-12-19)26(32)27(25(21)31,17-8-5-2)18-9-6-3/h11-12,14-15,30-31H,4-10,13,16-18H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466515 (US10800725, Compound 3) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466523 (US10800725, Compound 11) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(Br)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43BrO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466521 (US10800725, Compound 9) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(C)cc2)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)8-14-25-28(33)27(26(32)15-13-24-11-9-23(7)10-12-24)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h9-12,20-22,33-34H,8,13-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466523 (US10800725, Compound 11) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(Br)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43BrO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466519 (US10800725, Compound 7) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2C)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)12-14-25-28(33)27(26(32)15-13-24-11-9-8-10-23(24)7)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h8-11,20-22,33-34H,12-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466517 (US10800725, Compound 5) Show SMILES COc1cccc(CCC(=O)C2=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C2=O)c1 |c:11,t:19| Show InChI InChI=1S/C31H46O5/c1-20(2)11-13-25-28(33)27(26(32)14-12-23-9-8-10-24(19-23)36-7)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-10,19-22,33-34H,11-18H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466517 (US10800725, Compound 5) Show SMILES COc1cccc(CCC(=O)C2=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C2=O)c1 |c:11,t:19| Show InChI InChI=1S/C31H46O5/c1-20(2)11-13-25-28(33)27(26(32)14-12-23-9-8-10-24(19-23)36-7)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-10,19-22,33-34H,11-18H2,1-7H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466526 (US10800725, Compound 14) Show SMILES CCCCC1=C(O)C(CCCC)(CCCC)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:4,30| Show InChI InChI=1S/C27H37ClO4/c1-4-7-10-21-24(30)23(22(29)16-13-19-11-14-20(28)15-12-19)26(32)27(25(21)31,17-8-5-2)18-9-6-3/h11-12,14-15,30-31H,4-10,13,16-18H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466518 (US10800725, Compound 6) Show SMILES COc1ccc(CCC(=O)C2=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C2=O)cc1 |c:10,t:18| Show InChI InChI=1S/C31H46O5/c1-20(2)8-14-25-28(33)27(26(32)15-11-23-9-12-24(36-7)13-10-23)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h9-10,12-13,20-22,33-34H,8,11,14-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466513 (US10800725, Compound 1) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2Cl)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)11-13-23-27(33)26(25(32)14-12-22-9-7-8-10-24(22)31)29(35)30(28(23)34,17-15-20(3)4)18-16-21(5)6/h7-10,19-21,33-34H,11-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466525 (US10800725, Compound 13) Show SMILES CCCC1=C(O)C(CCC)(CCC)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:3,27| Show InChI InChI=1S/C24H31ClO4/c1-4-7-18-21(27)20(19(26)13-10-16-8-11-17(25)12-9-16)23(29)24(14-5-2,15-6-3)22(18)28/h8-9,11-12,27-28H,4-7,10,13-15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466516 (US10800725, Compound 4) Show SMILES COc1ccccc1CCC(=O)C1=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C1=O |c:13,t:21| Show InChI InChI=1S/C31H46O5/c1-20(2)12-14-24-28(33)27(25(32)15-13-23-10-8-9-11-26(23)36-7)30(35)31(29(24)34,18-16-21(3)4)19-17-22(5)6/h8-11,20-22,33-34H,12-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466518 (US10800725, Compound 6) Show SMILES COc1ccc(CCC(=O)C2=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C2=O)cc1 |c:10,t:18| Show InChI InChI=1S/C31H46O5/c1-20(2)8-14-25-28(33)27(26(32)15-11-23-9-12-24(36-7)13-10-23)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h9-10,12-13,20-22,33-34H,8,11,14-19H2,1-7H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466516 (US10800725, Compound 4) Show SMILES COc1ccccc1CCC(=O)C1=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C1=O |c:13,t:21| Show InChI InChI=1S/C31H46O5/c1-20(2)12-14-24-28(33)27(25(32)15-13-23-10-8-9-11-26(23)36-7)30(35)31(29(24)34,18-16-21(3)4)19-17-22(5)6/h8-11,20-22,33-34H,12-19H2,1-7H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466513 (US10800725, Compound 1) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2Cl)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)11-13-23-27(33)26(25(32)14-12-22-9-7-8-10-24(22)31)29(35)30(28(23)34,17-15-20(3)4)18-16-21(5)6/h7-10,19-21,33-34H,11-18H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466514 (US10800725, Compound 2) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2cccc(Cl)c2)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)10-12-24-27(33)26(25(32)13-11-22-8-7-9-23(31)18-22)29(35)30(28(24)34,16-14-20(3)4)17-15-21(5)6/h7-9,18-21,33-34H,10-17H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466520 (US10800725, Compound 8) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2cccc(C)c2)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)11-13-25-28(33)27(26(32)14-12-24-10-8-9-23(7)19-24)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-10,19-22,33-34H,11-18H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466522 (US10800725, Compound 10) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(F)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43FO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466515 (US10800725, Compound 3) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466514 (US10800725, Compound 2) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2cccc(Cl)c2)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)10-12-24-27(33)26(25(32)13-11-22-8-7-9-23(31)18-22)29(35)30(28(24)34,16-14-20(3)4)17-15-21(5)6/h7-9,18-21,33-34H,10-17H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466507 (US10800725, Compound 15) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2)=C1O |c:5,32| Show InChI InChI=1S/C30H44O4/c1-20(2)12-14-24-27(32)26(25(31)15-13-23-10-8-7-9-11-23)29(34)30(28(24)33,18-16-21(3)4)19-17-22(5)6/h7-11,20-22,32-33H,12-19H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha/beta/beta'/omega (Escherichia coli K-12)	BDBM50000054 (CHEMBL3228735) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)c1ccc(C)c3oc4c(C)c(=O)c(NC5CC(C)(C)[N+]([O-])C(C)(C)C5)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C |r,wU:12.13,8.107,51.53,46.48,1.0,wD:45.46,72.79,87.94,82.89,64.66,^1:35,(36.21,-4.82,;37.96,-4.15,;36.92,-3.01,;37.68,-1.67,;39.19,-1.98,;39.37,-3.5,;40.71,-4.27,;40.71,-5.81,;42.04,-3.5,;43.37,-4.27,;45.91,-10.38,;47.24,-11.15,;44.57,-11.13,;44.56,-12.67,;45.89,-13.46,;47.22,-12.69,;45.88,-15,;44.55,-15.75,;44.53,-17.29,;45.86,-18.08,;45.84,-19.62,;47.2,-17.31,;48.52,-18.08,;49.85,-17.33,;51.16,-18.1,;51.14,-19.65,;52.48,-17.34,;53.82,-18.12,;52.49,-15.82,;53.82,-15.05,;55.16,-15.82,;55.15,-17.35,;56.47,-18.11,;57.24,-19.44,;55.7,-19.44,;57.81,-17.36,;59.14,-18.13,;57.81,-15.81,;58.9,-14.72,;59.31,-16.21,;56.48,-15.04,;51.16,-15.05,;51.18,-13.51,;49.86,-12.74,;52.52,-12.74,;52.52,-11.2,;53.86,-10.43,;53.87,-8.91,;55.19,-11.22,;56.53,-10.45,;56.53,-8.91,;57.86,-11.22,;57.85,-12.76,;59.19,-13.53,;56.52,-13.53,;59.2,-10.45,;60.53,-11.24,;59.21,-8.91,;57.87,-8.14,;60.54,-8.16,;60.54,-6.6,;61.9,-5.85,;59.21,-5.83,;57.88,-6.6,;59.23,-4.29,;60.88,-5.16,;60.49,-3.4,;60.01,-1.93,;58.47,-1.93,;57.99,-3.38,;56.65,-4.15,;56.65,-5.69,;55.32,-3.38,;53.98,-4.13,;51.19,-10.43,;49.86,-11.19,;55.32,-1.82,;53.99,-1.05,;56.66,-1.05,;49.86,-15.8,;48.53,-15.03,;47.21,-15.77,;43.24,-10.36,;43.25,-8.82,;41.9,-11.12,;40.57,-10.34,;40.59,-8.8,;39.24,-11.1,;39.22,-12.64,;40.55,-13.42,;37.89,-13.39,;37.9,-10.31,;36.57,-11.08,;37.91,-8.77,;39.26,-8.02,;36.58,-8,;36.6,-6.46,;35.27,-5.67,;37.95,-5.69,;39.26,-6.46,;42.02,-1.96,;43.36,-1.19,;40.69,-1.19,)| Show InChI InChI=1S/C71H102N13O17/c1-33(2)48-66(94)82-27-21-23-43(82)64(92)78(17)31-45(85)80(19)55(35(5)6)68(96)99-39(11)50(62(90)74-48)76-60(88)42-26-25-37(9)58-52(42)73-54-47(53(57(87)38(10)59(54)101-58)72-41-29-70(13,14)84(98)71(15,16)30-41)61(89)77-51-40(12)100-69(97)56(36(7)8)81(20)46(86)32-79(18)65(93)44-24-22-28-83(44)67(95)49(34(3)4)75-63(51)91/h25-26,33-36,39-41,43-44,48-51,55-56,72H,21-24,27-32H2,1-20H3,(H,74,90)(H,75,91)(H,76,88)(H,77,89)/t39-,40-,43+,44+,48-,49-,50+,51+,55+,56+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA-dependent RNA polymerase				J Med Chem 22: 1051-5 (1979) BindingDB Entry DOI: 10.7270/Q2SQ91WG
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466526 (US10800725, Compound 14) Show SMILES CCCCC1=C(O)C(CCCC)(CCCC)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:4,30| Show InChI InChI=1S/C27H37ClO4/c1-4-7-10-21-24(30)23(22(29)16-13-19-11-14-20(28)15-12-19)26(32)27(25(21)31,17-8-5-2)18-9-6-3/h11-12,14-15,30-31H,4-10,13,16-18H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466517 (US10800725, Compound 5) Show SMILES COc1cccc(CCC(=O)C2=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C2=O)c1 |c:11,t:19| Show InChI InChI=1S/C31H46O5/c1-20(2)11-13-25-28(33)27(26(32)14-12-23-9-8-10-24(19-23)36-7)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-10,19-22,33-34H,11-18H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466523 (US10800725, Compound 11) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccc(Br)cc2)=C1O |c:5,33| Show InChI InChI=1S/C30H43BrO4/c1-19(2)7-13-24-27(33)26(25(32)14-10-22-8-11-23(31)12-9-22)29(35)30(28(24)34,17-15-20(3)4)18-16-21(5)6/h8-9,11-12,19-21,33-34H,7,10,13-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466518 (US10800725, Compound 6) Show SMILES COc1ccc(CCC(=O)C2=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C2=O)cc1 |c:10,t:18| Show InChI InChI=1S/C31H46O5/c1-20(2)8-14-25-28(33)27(26(32)15-11-23-9-12-24(36-7)13-10-23)30(35)31(29(25)34,18-16-21(3)4)19-17-22(5)6/h9-10,12-13,20-22,33-34H,8,11,14-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466507 (US10800725, Compound 15) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2)=C1O |c:5,32| Show InChI InChI=1S/C30H44O4/c1-20(2)12-14-24-27(32)26(25(31)15-13-23-10-8-7-9-11-23)29(34)30(28(24)33,18-16-21(3)4)19-17-22(5)6/h7-11,20-22,32-33H,12-19H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466511 (US10800725, Compound 19) Show SMILES CCCCCC1=C(O)C(CCCCC)(CCCCC)C(=O)C(C(=O)CCc2ccccc2)=C1O |c:5,32| Show InChI InChI=1S/C30H44O4/c1-4-7-11-18-24-27(32)26(25(31)20-19-23-16-12-10-13-17-23)29(34)30(28(24)33,21-14-8-5-2)22-15-9-6-3/h10,12-13,16-17,32-33H,4-9,11,14-15,18-22H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466516 (US10800725, Compound 4) Show SMILES COc1ccccc1CCC(=O)C1=C(O)C(CCC(C)C)=C(O)C(CCC(C)C)(CCC(C)C)C1=O |c:13,t:21| Show InChI InChI=1S/C31H46O5/c1-20(2)12-14-24-28(33)27(25(32)15-13-23-10-8-9-11-26(23)36-7)30(35)31(29(24)34,18-16-21(3)4)19-17-22(5)6/h8-11,20-22,33-34H,12-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466525 (US10800725, Compound 13) Show SMILES CCCC1=C(O)C(CCC)(CCC)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:3,27| Show InChI InChI=1S/C24H31ClO4/c1-4-7-18-21(27)20(19(26)13-10-16-8-11-17(25)12-9-16)23(29)24(14-5-2,15-6-3)22(18)28/h8-9,11-12,27-28H,4-7,10,13-15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466513 (US10800725, Compound 1) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2Cl)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)11-13-23-27(33)26(25(32)14-12-22-9-7-8-10-24(22)31)29(35)30(28(23)34,17-15-20(3)4)18-16-21(5)6/h7-10,19-21,33-34H,11-18H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466514 (US10800725, Compound 2) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2cccc(Cl)c2)=C1O |c:5,33| Show InChI InChI=1S/C30H43ClO4/c1-19(2)10-12-24-27(33)26(25(32)13-11-22-8-7-9-23(31)18-22)29(35)30(28(24)34,16-14-20(3)4)17-15-21(5)6/h7-9,18-21,33-34H,10-17H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466512 (US10800725, Compound 20) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)C(C)Cc2ccccc2)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)13-14-25-28(33)26(27(32)23(7)19-24-11-9-8-10-12-24)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-12,20-23,33-34H,13-19H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466511 (US10800725, Compound 19) Show SMILES CCCCCC1=C(O)C(CCCCC)(CCCCC)C(=O)C(C(=O)CCc2ccccc2)=C1O |c:5,32| Show InChI InChI=1S/C30H44O4/c1-4-7-11-18-24-27(32)26(25(31)20-19-23-16-12-10-13-17-23)29(34)30(28(24)33,21-14-8-5-2)22-15-9-6-3/h10,12-13,16-17,32-33H,4-9,11,14-15,18-22H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466525 (US10800725, Compound 13) Show SMILES CCCC1=C(O)C(CCC)(CCC)C(=O)C(C(=O)CCc2ccc(Cl)cc2)=C1O |c:3,27| Show InChI InChI=1S/C24H31ClO4/c1-4-7-18-21(27)20(19(26)13-10-16-8-11-17(25)12-9-16)23(29)24(14-5-2,15-6-3)22(18)28/h8-9,11-12,27-28H,4-7,10,13-15H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha ()	BDBM466507 (US10800725, Compound 15) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)CCc2ccccc2)=C1O |c:5,32| Show InChI InChI=1S/C30H44O4/c1-20(2)12-14-24-27(32)26(25(31)15-13-23-10-8-7-9-11-23)29(34)30(28(24)33,18-16-21(3)4)19-17-22(5)6/h7-11,20-22,32-33H,12-19H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair
DNA-directed RNA polymerase subunit alpha (Escherichia coli K-12)	BDBM466512 (US10800725, Compound 20) Show SMILES CC(C)CCC1=C(O)C(CCC(C)C)(CCC(C)C)C(=O)C(C(=O)C(C)Cc2ccccc2)=C1O |c:5,33| Show InChI InChI=1S/C31H46O4/c1-20(2)13-14-25-28(33)26(27(32)23(7)19-24-11-9-8-10-12-24)30(35)31(29(25)34,17-15-21(3)4)18-16-22(5)6/h8-12,20-23,33-34H,13-19H2,1-7H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...				US Patent US10800725 (2020) BindingDB Entry DOI: 10.7270/Q2GB274V
					More data for this Ligand-Target Pair

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