Compile Data Set for Download or QSAR

Found 16 hits Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 1 group D member 2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643181 (US20240002380, Example 10) Show SMILES Cn1ncc2cnc(Oc3ccccc3-c3cccnc3)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643199 (US20240002380, Example 59) Show SMILES O(c1ccc2ccncc2n1)c1ccccc1-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643191 (US20240002380, Example 45) Show SMILES O(c1ccc2cnccc2n1)c1ccccc1-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643190 (US20240002380, Example 44) Show SMILES FC(F)(F)c1ccccc1Oc1ccc2ccncc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643178 (US20240002380, Example 4) Show SMILES Cc1cccc(c1)-c1ccccc1Oc1ccc2ncn(C)c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643177 (US20240002380, Example 3) Show SMILES Cn1cnc2ccc(Oc3ccccc3-c3ccccc3)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM50366239 (CHEMBL1961797) Show SMILES CCCCCNC(=O)N1CCC(CN(Cc2ccc(s2)[N+]([O-])=O)Cc2ccc(Cl)cc2)C1 Show InChI InChI=1S/C23H31ClN4O3S/c1-2-3-4-12-25-23(29)27-13-11-19(16-27)15-26(14-18-5-7-20(24)8-6-18)17-21-9-10-22(32-21)28(30)31/h5-10,19H,2-4,11-17H2,1H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Increased REV-ERB-beta LBD dependent repressor activity in HEK293 cell reporter assay				Nature 485: 62-68 (2012) Article DOI: 10.1038/nature11030 BindingDB Entry DOI: 10.7270/Q2445N00
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM50366238 (CHEMBL1961796) Show SMILES CCOC(=O)N1CCC(CN(Cc2ccc(s2)[N+]([O-])=O)Cc2ccc(Cl)cc2)C1 Show InChI InChI=1S/C20H24ClN3O4S/c1-2-28-20(25)23-10-9-16(13-23)12-22(11-15-3-5-17(21)6-4-15)14-18-7-8-19(29-18)24(26)27/h3-8,16H,2,9-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Increased REV-ERB-beta LBD dependent repressor activity in HEK293 cell reporter assay				Nature 485: 62-68 (2012) Article DOI: 10.1038/nature11030 BindingDB Entry DOI: 10.7270/Q2445N00
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643179 (US20240002380, Example 5) Show SMILES Cn1cnc2ccc(Oc3ccccc3-c3cccc(F)c3)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM50095837 (CHEMBL3590573) Show SMILES CN1CCC(Cc2cccc(CNC3(CCCC3)c3ccc(F)cc3)c2)CC1 Show InChI InChI=1S/C18H29N7O4/c19-7-5-3-1-2-4-6-8-21-17(28)14-12(26)13(27)18(29-14)25-10-24-11-15(20)22-9-23-16(11)25/h9-10,12-14,18,26-27H,1-8,19H2,(H,21,28)(H2,20,22,23)/t12?,13?,14-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of REV-ERBbeta (unknown origin) expressed in HEK293 cells incubated for 24 hrs assessed as inhibition of receptor-mediated transcriptional...				J Med Chem 58: 5900-15 (2015) Article DOI: 10.1021/acs.jmedchem.5b00511 BindingDB Entry DOI: 10.7270/Q26H4K40
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643197 (US20240002380, Example 56) Show SMILES O(c1ccc2cnccc2n1)c1cccc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643195 (US20240002380, Example 51) Show SMILES O(c1cccc(c1)-c1ccccc1)c1ccc2ccncc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643188 (US20240002380, Example 34) Show SMILES FC(F)(F)c1cc(Oc2ccccc2-c2ccccc2)nc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643201 (US20240002380, Example 68) Show SMILES O(c1ccc2ncccc2n1)c1ccccc1-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM643192 (US20240002380, Example 46) Show SMILES FC(F)(F)c1ccccc1Oc1ccc2cnccc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group D member 2 (Homo sapiens (Human))	BDBM50095836 (CHEMBL3590544) Show SMILES CN1CCN(Cc2cc(CNC3(CCCC3)c3ccccc3F)ccc2O)CC1 Show InChI InChI=1S/C14H20N6O4/c1-3-6(2)19-13(23)10-8(21)9(22)14(24-10)20-5-18-7-11(15)16-4-17-12(7)20/h4-6,8-10,14,21-22H,3H2,1-2H3,(H,19,23)(H2,15,16,17)/t6?,8?,9?,10-,14+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of REV-ERBbeta (unknown origin) expressed in HEK293 cells incubated for 24 hrs assessed as inhibition of receptor-mediated transcriptional...				J Med Chem 58: 5900-15 (2015) Article DOI: 10.1021/acs.jmedchem.5b00511 BindingDB Entry DOI: 10.7270/Q26H4K40
					More data for this Ligand-Target Pair