Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trypsin-3 (Homo sapiens (Human)) | BDBM50421510 (CHEMBL239127) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Compound was tested for inhibition of bovine beta trypsin | Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449678 (CHEMBL4164510) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449679 (CHEMBL4167071) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449677 (CHEMBL4172393) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449680 (CHEMBL4170662) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449683 (CHEMBL4172833) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449676 (CHEMBL4162159) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 134 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449682 (CHEMBL4176209) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 335 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449675 (CHEMBL4175285) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 369 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50449681 (CHEMBL4165595) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 402 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50037996 (1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory Activity against bovine beta-trypsin | J Med Chem 43: 3033-44 (2000) BindingDB Entry DOI: 10.7270/Q20R9Q3N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50124947 (CHEMBL453539) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 4.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 mins | Eur J Med Chem 155: 695-704 (2018) Article DOI: 10.1016/j.ejmech.2018.06.029 BindingDB Entry DOI: 10.7270/Q29026CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50092660 (4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometry | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50387180 (CHEMBL2047998) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.68E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometry | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50387183 (CHEMBL2048000) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.76E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometry | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50387182 (CHEMBL2048003) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 7.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometry | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50387181 (CHEMBL2047999) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.09E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometry | Bioorg Med Chem Lett 22: 4839-43 (2012) Article DOI: 10.1016/j.bmcl.2012.05.046 BindingDB Entry DOI: 10.7270/Q2QV3NKC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50131988 (2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Beta-Trypsin inhibitory activity of compound was determined | J Med Chem 46: 3865-76 (2003) Article DOI: 10.1021/jm030050p BindingDB Entry DOI: 10.7270/Q23T9J0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50131981 (CHEMBL340098 | N-{[1-(Benzothiazole-2-carbonyl)-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Beta-Trypsin inhibitory activity of compound was determined | J Med Chem 46: 3865-76 (2003) Article DOI: 10.1021/jm030050p BindingDB Entry DOI: 10.7270/Q23T9J0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50131976 (1-Acetyl-pyrrolidine-2-carboxylic acid [1-(benzoth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Beta-Trypsin inhibitory activity of compound was determined | J Med Chem 46: 3865-76 (2003) Article DOI: 10.1021/jm030050p BindingDB Entry DOI: 10.7270/Q23T9J0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50131984 (1-Acetyl-azetidine-2-carboxylic acid [1-(benzothia...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Beta-Trypsin inhibitory activity of compound was determined | J Med Chem 46: 3865-76 (2003) Article DOI: 10.1021/jm030050p BindingDB Entry DOI: 10.7270/Q23T9J0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin-3 (Homo sapiens (Human)) | BDBM50131978 (1-Benzyl-pyrrolidine-2-carboxylic acid [1-(benzoth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Beta-Trypsin inhibitory activity of compound was determined | J Med Chem 46: 3865-76 (2003) Article DOI: 10.1021/jm030050p BindingDB Entry DOI: 10.7270/Q23T9J0V | |||||||||||
More data for this Ligand-Target Pair |