Compile Data Set for Download or QSAR

Found 35 hits Enz. Inhib. hit(s) with Target = 'Transcription factor 7-like 2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50014098 (CHEMBL3260852) Show SMILES Oc1noc2cc(CCc3nn[nH]n3)ccc12 Show InChI InChI=1S/C10H9N5O2/c16-10-7-3-1-6(5-8(7)17-13-10)2-4-9-11-14-15-12-9/h1,3,5H,2,4H2,(H,13,16)(H,11,12,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of beta-catenin/T cell factor (unknown origin)				Bioorg Med Chem Lett 24: 2546-54 (2014) Article DOI: 10.1016/j.bmcl.2014.03.095 BindingDB Entry DOI: 10.7270/Q2FX7C05
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50014132 (CHEMBL2323032) Show SMILES On1ncc2cc(CCc3nn[nH]n3)ccc12 Show InChI InChI=1S/C10H10N6O/c17-16-9-3-1-7(5-8(9)6-11-16)2-4-10-12-14-15-13-10/h1,3,5-6,17H,2,4H2,(H,12,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM32102 (1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...) Show SMILES Cn1ncnc2c1nc(=O)n(C)c2=O Show InChI InChI=1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50014132 (CHEMBL2323032) Show SMILES On1ncc2cc(CCc3nn[nH]n3)ccc12 Show InChI InChI=1S/C10H10N6O/c17-16-9-3-1-7(5-8(9)6-11-16)2-4-10-12-14-15-13-10/h1,3,5-6,17H,2,4H2,(H,12,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM32102 (1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...) Show SMILES Cn1ncnc2c1nc(=O)n(C)c2=O Show InChI InChI=1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50094484 (CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...) Show SMILES COc1c(C[C@H](C)O)c2c3c(C[C@H](C)O)c(OC)c(=O)c4c(O)cc5OCOc6cc(O)c(c2c6c5c34)c1=O |r| Show InChI InChI=1S/C27H29NO3/c29-26(27(30,23-12-6-2-7-13-23)24-14-8-3-9-15-24)31-25-17-20-28(21-18-25)19-16-22-10-4-1-5-11-22/h1-15,25,30H,16-21H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50094600 (CHEMBL2323029) Show SMILES OC(=O)c1ccc2nc(-c3ccc(Cl)cc3)c(nc2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27N5/c1-16-17(2)29(18(3)19-10-6-4-7-11-19)24-21(16)23(26-15-14-25)27-22(28-24)20-12-8-5-9-13-20/h4-13,18H,14-15,25H2,1-3H3,(H,26,27,28)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50094600 (CHEMBL2323029) Show SMILES OC(=O)c1ccc2nc(-c3ccc(Cl)cc3)c(nc2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27N5/c1-16-17(2)29(18(3)19-10-6-4-7-11-19)24-21(16)23(26-15-14-25)27-22(28-24)20-12-8-5-9-13-20/h4-13,18H,14-15,25H2,1-3H3,(H,26,27,28)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50489463 (CHEMBL2323031) Show SMILES OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1 Show InChI InChI=1S/C20H16N4O5/c1-2-10-24-15-9-4-3-8-14(15)16(19(24)27)22-23-18(26)17(25)21-13-7-5-6-12(11-13)20(28)29/h2-9,11H,1,10H2,(H,21,25)(H,23,26)(H,28,29)/b22-16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50249236 ((R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)...) Show SMILES COc1cc(=O)c2c(O)c(OC)c(C[C@@H](C)OC(=O)Oc3ccc(O)cc3)c3c4c(C[C@@H](C)OC(=O)c5ccccc5)c(OC)c(O)c5c4c(c(OC)cc5=O)c1c23 |r| Show InChI InChI=1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45,48-49H,16-17H2,1-6H3/t20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50489463 (CHEMBL2323031) Show SMILES OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1 Show InChI InChI=1S/C20H16N4O5/c1-2-10-24-15-9-4-3-8-14(15)16(19(24)27)22-23-18(26)17(25)21-13-7-5-6-12(11-13)20(28)29/h2-9,11H,1,10H2,(H,21,25)(H,23,26)(H,28,29)/b22-16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50094597 (CHEMBL2323028) Show SMILES OC(=O)c1cc(on1)-c1ccc(Oc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C30H30N4/c1-20-22(3)34(23(4)25-16-10-6-11-17-25)30-27(20)29(31-21(2)24-14-8-5-9-15-24)32-28(33-30)26-18-12-7-13-19-26/h5-19,21,23H,1-4H3,(H,31,32,33)/t21-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50489464 (CHEMBL2323030) Show SMILES COc1cccc(\C=C2\SC(=S)N(CCC(O)=O)C2=O)c1OC Show InChI InChI=1S/C15H15NO5S2/c1-20-10-5-3-4-9(13(10)21-2)8-11-14(19)16(15(22)23-11)7-6-12(17)18/h3-5,8H,6-7H2,1-2H3,(H,17,18)/b11-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50094484 (CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...) Show SMILES COc1c(C[C@H](C)O)c2c3c(C[C@H](C)O)c(OC)c(=O)c4c(O)cc5OCOc6cc(O)c(c2c6c5c34)c1=O |r| Show InChI InChI=1S/C27H29NO3/c29-26(27(30,23-12-6-2-7-13-23)24-14-8-3-9-15-24)31-25-17-20-28(21-18-25)19-16-22-10-4-1-5-11-22/h1-15,25,30H,16-21H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50094597 (CHEMBL2323028) Show SMILES OC(=O)c1cc(on1)-c1ccc(Oc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C30H30N4/c1-20-22(3)34(23(4)25-16-10-6-11-17-25)30-27(20)29(31-21(2)24-14-8-5-9-15-24)32-28(33-30)26-18-12-7-13-19-26/h5-19,21,23H,1-4H3,(H,31,32,33)/t21-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay				ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484962 (CHEMBL2018626) Show SMILES CNc1nc(NCc2ccc(cc2)C(=O)NCCc2ccc(F)cc2)c2cc(C)ccc2n1 Show InChI InChI=1S/C26H26FN5O/c1-17-3-12-23-22(15-17)24(32-26(28-2)31-23)30-16-19-4-8-20(9-5-19)25(33)29-14-13-18-6-10-21(27)11-7-18/h3-12,15H,13-14,16H2,1-2H3,(H,29,33)(H2,28,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484965 (CHEMBL2018615) Show SMILES CCCCNc1nc(NCc2ccc(cc2)C(=O)Nc2ccc(F)cc2)c2ccccc2n1 Show InChI InChI=1S/C26H26FN5O/c1-2-3-16-28-26-31-23-7-5-4-6-22(23)24(32-26)29-17-18-8-10-19(11-9-18)25(33)30-21-14-12-20(27)13-15-21/h4-15H,2-3,16-17H2,1H3,(H,30,33)(H2,28,29,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484959 (CHEMBL2018726) Show SMILES CN(C)c1nc(NCc2ccc(cc2)C(=O)NCCc2ccc(F)cc2)c2cc(C)ccc2n1 Show InChI InChI=1S/C27H28FN5O/c1-18-4-13-24-23(16-18)25(32-27(31-24)33(2)3)30-17-20-5-9-21(10-6-20)26(34)29-15-14-19-7-11-22(28)12-8-19/h4-13,16H,14-15,17H2,1-3H3,(H,29,34)(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484954 (CHEMBL2018623) Show SMILES CN(C)c1nc(NCc2ccc(cc2)C(=O)NCc2ccc(F)cc2)c2cc(C)ccc2n1 Show InChI InChI=1S/C26H26FN5O/c1-17-4-13-23-22(14-17)24(31-26(30-23)32(2)3)28-15-18-5-9-20(10-6-18)25(33)29-16-19-7-11-21(27)12-8-19/h4-14H,15-16H2,1-3H3,(H,29,33)(H,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484955 (CHEMBL2018727) Show SMILES CCCNc1nc(NCc2ccc(cc2)C(=O)NCCc2ccc(F)cc2)c2cc(C)ccc2n1 Show InChI InChI=1S/C28H30FN5O/c1-3-15-31-28-33-25-13-4-19(2)17-24(25)26(34-28)32-18-21-5-9-22(10-6-21)27(35)30-16-14-20-7-11-23(29)12-8-20/h4-13,17H,3,14-16,18H2,1-2H3,(H,30,35)(H2,31,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484951 (CHEMBL2018597) Show SMILES CCCNc1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccccc2n1 Show InChI InChI=1S/C25H24FN5O/c1-2-15-27-25-30-22-6-4-3-5-21(22)23(31-25)28-16-17-7-13-20(14-8-17)29-24(32)18-9-11-19(26)12-10-18/h3-14H,2,15-16H2,1H3,(H,29,32)(H2,27,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484952 (CHEMBL2018621) Show SMILES CN(C)c1nc(NCc2ccc(cc2)C(=O)Nc2ccc(Cl)nc2)c2cc(C)ccc2n1 Show InChI InChI=1S/C24H23ClN6O/c1-15-4-10-20-19(12-15)22(30-24(29-20)31(2)3)27-13-16-5-7-17(8-6-16)23(32)28-18-9-11-21(25)26-14-18/h4-12,14H,13H2,1-3H3,(H,28,32)(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484953 (CHEMBL2018622) Show SMILES CCCNc1nc(NCc2ccc(cc2)C(=O)Nc2ccc(Cl)nc2)c2cc(C)ccc2n1 Show InChI InChI=1S/C25H25ClN6O/c1-3-12-27-25-31-21-10-4-16(2)13-20(21)23(32-25)29-14-17-5-7-18(8-6-17)24(33)30-19-9-11-22(26)28-15-19/h4-11,13,15H,3,12,14H2,1-2H3,(H,30,33)(H2,27,29,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484958 (CHEMBL2018734) Show SMILES CN(C)c1nc(NCc2ccc(cc2)C(=O)NC2CCN(Cc3ccc(F)cc3)CC2)c2cc(C)ccc2n1 Show InChI InChI=1S/C31H35FN6O/c1-21-4-13-28-27(18-21)29(36-31(35-28)37(2)3)33-19-22-5-9-24(10-6-22)30(39)34-26-14-16-38(17-15-26)20-23-7-11-25(32)12-8-23/h4-13,18,26H,14-17,19-20H2,1-3H3,(H,34,39)(H,33,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484949 (CHEMBL2018614) Show SMILES CCCNc1nc(NCc2ccc(cc2)C(=O)Nc2ccc(F)cc2)c2ccccc2n1 Show InChI InChI=1S/C25H24FN5O/c1-2-15-27-25-30-22-6-4-3-5-21(22)23(31-25)28-16-17-7-9-18(10-8-17)24(32)29-20-13-11-19(26)12-14-20/h3-14H,2,15-16H2,1H3,(H,29,32)(H2,27,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484961 (CHEMBL2018598) Show SMILES CCNc1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccccc2n1 Show InChI InChI=1S/C24H22FN5O/c1-2-26-24-29-21-6-4-3-5-20(21)22(30-24)27-15-16-7-13-19(14-8-16)28-23(31)17-9-11-18(25)12-10-17/h3-14H,2,15H2,1H3,(H,28,31)(H2,26,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484967 (CHEMBL2018733) Show SMILES CCCNc1nc(NCc2ccc(cc2)C(=O)NC2CCN(Cc3ccc(F)cc3)CC2)c2cc(C)ccc2n1 Show InChI InChI=1S/C32H37FN6O/c1-3-16-34-32-37-29-13-4-22(2)19-28(29)30(38-32)35-20-23-5-9-25(10-6-23)31(40)36-27-14-17-39(18-15-27)21-24-7-11-26(33)12-8-24/h4-13,19,27H,3,14-18,20-21H2,1-2H3,(H,36,40)(H2,34,35,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484966 (CHEMBL2018617) Show SMILES CN(C)c1nc(NCc2ccc(cc2)C(=O)Nc2ccc(F)cc2)c2ccccc2n1 Show InChI InChI=1S/C24H22FN5O/c1-30(2)24-28-21-6-4-3-5-20(21)22(29-24)26-15-16-7-9-17(10-8-16)23(31)27-19-13-11-18(25)12-14-19/h3-14H,15H2,1-2H3,(H,27,31)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484957 (CHEMBL2018732) Show SMILES CNc1nc(NCc2ccc(cc2)C(=O)NC2CCN(Cc3ccc(F)cc3)CC2)c2cc(C)ccc2n1 Show InChI InChI=1S/C30H33FN6O/c1-20-3-12-27-26(17-20)28(36-30(32-2)35-27)33-18-21-4-8-23(9-5-21)29(38)34-25-13-15-37(16-14-25)19-22-6-10-24(31)11-7-22/h3-12,17,25H,13-16,18-19H2,1-2H3,(H,34,38)(H2,32,33,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484956 (CHEMBL2018728) Show SMILES CN(C)c1nc(NCc2ccc(cc2)C(=O)N[C@H]2C[C@@H]2c2ccccc2)c2cc(C)ccc2n1 |r| Show InChI InChI=1S/C28H29N5O/c1-18-9-14-24-23(15-18)26(32-28(31-24)33(2)3)29-17-19-10-12-21(13-11-19)27(34)30-25-16-22(25)20-7-5-4-6-8-20/h4-15,22,25H,16-17H2,1-3H3,(H,30,34)(H,29,31,32)/t22-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484963 (CHEMBL2018729) Show SMILES CCNc1nc(NCc2ccc(cc2)C(=O)N[C@H]2C[C@@H]2c2ccccc2)c2cc(C)ccc2n1 |r| Show InChI InChI=1S/C28H29N5O/c1-3-29-28-32-24-14-9-18(2)15-23(24)26(33-28)30-17-19-10-12-21(13-11-19)27(34)31-25-16-22(25)20-7-5-4-6-8-20/h4-15,22,25H,3,16-17H2,1-2H3,(H,31,34)(H2,29,30,32,33)/t22-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484950 (CHEMBL569102) Show SMILES CNc1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccccc2n1 Show InChI InChI=1S/C23H20FN5O/c1-25-23-28-20-5-3-2-4-19(20)21(29-23)26-14-15-6-12-18(13-7-15)27-22(30)16-8-10-17(24)11-9-16/h2-13H,14H2,1H3,(H,27,30)(H2,25,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484948 (CHEMBL2018612) Show SMILES CCNc1nc(NCc2ccc(cc2)C(=O)Nc2ccc(F)cc2)c2ccccc2n1 Show InChI InChI=1S/C24H22FN5O/c1-2-26-24-29-21-6-4-3-5-20(21)22(30-24)27-15-16-7-9-17(10-8-16)23(31)28-19-13-11-18(25)12-14-19/h3-14H,2,15H2,1H3,(H,28,31)(H2,26,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484960 (CHEMBL2018618) Show SMILES CC1CN(CCN1)c1nc(NCc2ccc(cc2)C(=O)Nc2ccc(F)cc2)c2ccccc2n1 Show InChI InChI=1S/C27H27FN6O/c1-18-17-34(15-14-29-18)27-32-24-5-3-2-4-23(24)25(33-27)30-16-19-6-8-20(9-7-19)26(35)31-22-12-10-21(28)11-13-22/h2-13,18,29H,14-17H2,1H3,(H,31,35)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair
Transcription factor 7-like 2 (Homo sapiens (Human))	BDBM50484964 (CHEMBL2018735) Show SMILES CC1CN(CCN1)c1nc(NCc2ccc(cc2)C(=O)NC2CCN(Cc3ccc(F)cc3)CC2)c2cc(C)ccc2n1 Show InChI InChI=1S/C34H40FN7O/c1-23-3-12-31-30(19-23)32(40-34(39-31)42-18-15-36-24(2)21-42)37-20-25-4-8-27(9-5-25)33(43)38-29-13-16-41(17-14-29)22-26-6-10-28(35)11-7-26/h3-12,19,24,29,36H,13-18,20-22H2,1-2H3,(H,38,43)(H,37,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibition of beta-casein/TCF4 pathway expressed in HCT116 cells containing delta45S mutant after 24 hrs by luciferase reporter gene assay				J Med Chem 55: 1346-59 (2012) Article DOI: 10.1021/jm201494a BindingDB Entry DOI: 10.7270/Q21R6TB6
					More data for this Ligand-Target Pair