Found 95 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 4' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ubiquitin carboxyl-terminal hydrolase 4
(Homo sapiens (Human)) | BDBM50514113
(CHEMBL4593739)Show InChI InChI=1S/C17H15ClN2O2/c1-3-12-4-6-13(7-5-12)10-19-17(22)15-8-14(11-20(15)2)16(21)9-18/h1,4-8,11H,9-10H2,2H3,(H,19,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Dana-Farber Cancer Institute
Curated by ChEMBL
| Assay Description
Inhibition of USP4 in human U2OS using Ub-TAMRA substrate by Ub-Rhodamine fluorescent intensity assay |
J Med Chem 63: 2731-2750 (2020)
Article DOI: 10.1021/acs.jmedchem.9b01138
BindingDB Entry DOI: 10.7270/Q2GF0XTC |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393448
(CHEMBL2159507)Show SMILES CN(C)CCCOc1ccc(NC(=O)c2cc(C#N)c(Sc3c(Cl)cncc3Cl)s2)cc1 Show InChI InChI=1S/C22H20Cl2N4O2S2/c1-28(2)8-3-9-30-16-6-4-15(5-7-16)27-21(29)19-10-14(11-25)22(31-19)32-20-17(23)12-26-13-18(20)24/h4-7,10,12-13H,3,8-9H2,1-2H3,(H,27,29) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50436151
(CHEMBL2398212)Show InChI InChI=1S/C13H3ClN4O/c14-6-1-2-7-8(3-6)13(19)12-11(7)17-9(4-15)10(5-16)18-12/h1-3H | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393446
(CHEMBL2159505)Show SMILES CS(=O)(=O)c1ccc(NC(=O)c2cc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H11Cl2N3O5S3/c1-30(26,27)10-4-2-9(3-5-10)21-16(23)14-6-13(22(24)25)17(28-14)29-15-11(18)7-20-8-12(15)19/h2-8H,1H3,(H,21,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393444
(CHEMBL2159503)Show SMILES CN(C)CCCOc1ccc(NC(=O)c2cc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C21H20Cl2N4O4S2/c1-26(2)8-3-9-31-14-6-4-13(5-7-14)25-20(28)18-10-17(27(29)30)21(32-18)33-19-15(22)11-24-12-16(19)23/h4-7,10-12H,3,8-9H2,1-2H3,(H,25,28) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393445
(CHEMBL2159504)Show SMILES COc1ccc(NC(=O)c2cc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H11Cl2N3O4S2/c1-26-10-4-2-9(3-5-10)21-16(23)14-6-13(22(24)25)17(27-14)28-15-11(18)7-20-8-12(15)19/h2-8H,1H3,(H,21,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393449
(CHEMBL2159508)Show SMILES CS(=O)(=O)c1ccc(NC(=O)c2cc(C#N)c(Sc3c(Cl)cncc3Cl)s2)cc1 Show InChI InChI=1S/C18H11Cl2N3O3S3/c1-29(25,26)12-4-2-11(3-5-12)23-17(24)15-6-10(7-21)18(27-15)28-16-13(19)8-22-9-14(16)20/h2-6,8-9H,1H3,(H,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
| | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393450
(CHEMBL2159500)Show SMILES CC(=O)c1cc(c(Sc2c(Cl)cncc2Cl)s1)[N+]([O-])=O Show InChI InChI=1S/C11H6Cl2N2O3S2/c1-5(16)9-2-8(15(17)18)11(19-9)20-10-6(12)3-14-4-7(10)13/h2-4H,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393442
(CHEMBL2159501)Show SMILES CN1CCC(CC1)NC(=O)c1cc(c(Sc2c(Cl)cncc2Cl)s1)[N+]([O-])=O Show InChI InChI=1S/C16H16Cl2N4O3S2/c1-21-4-2-9(3-5-21)20-15(23)13-6-12(22(24)25)16(26-13)27-14-10(17)7-19-8-11(14)18/h6-9H,2-5H2,1H3,(H,20,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 4
(Homo sapiens (Human)) | BDBM50437693
(VIALININ A)Show SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1 Show InChI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Agriculture
Curated by ChEMBL
| Assay Description
Inhibition of human USP4 using Ub-AMC as substrate after 60 mins by fluorometric analysis |
Bioorg Med Chem Lett 23: 4328-31 (2013)
Article DOI: 10.1016/j.bmcl.2013.05.093
BindingDB Entry DOI: 10.7270/Q2T15528 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538560
(CHEMBL4640002)Show SMILES Clc1cc2C[C@@H](Oc2c(c1)-c1ccnc2cc(CN3C(=O)CCC3=O)sc12)C(=O)N1CCNCC1 |r| Show InChI InChI=1S/C25H23ClN4O4S/c26-15-9-14-10-20(25(33)29-7-5-27-6-8-29)34-23(14)18(11-15)17-3-4-28-19-12-16(35-24(17)19)13-30-21(31)1-2-22(30)32/h3-4,9,11-12,20,27H,1-2,5-8,10,13H2/t20-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393441
(CHEMBL2159499)Show SMILES CC(=O)c1cc(c(Sc2c(Cl)cccc2Cl)s1)[N+]([O-])=O Show InChI InChI=1S/C12H7Cl2NO3S2/c1-6(16)10-5-9(15(17)18)12(19-10)20-11-7(13)3-2-4-8(11)14/h2-5H,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL4569978
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393437
(CHEMBL2159495)Show SMILES CC(=O)c1cc(c(Sc2cccc(Cl)c2Cl)s1)[N+]([O-])=O Show InChI InChI=1S/C12H7Cl2NO3S2/c1-6(16)10-5-8(15(17)18)12(20-10)19-9-4-2-3-7(13)11(9)14/h2-5H,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL5281075
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538557
(CHEMBL4633562)Show SMILES Clc1cc2C[C@@H](Oc2c(c1)-c1ccnc2cc(Cn3cnccc3=O)sc12)C(=O)N1CCNCC1 |r| Show InChI InChI=1S/C25H22ClN5O3S/c26-16-9-15-10-21(25(33)30-7-5-27-6-8-30)34-23(15)19(11-16)18-1-4-29-20-12-17(35-24(18)20)13-31-14-28-3-2-22(31)32/h1-4,9,11-12,14,21,27H,5-8,10,13H2/t21-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393443
(CHEMBL2159502)Show SMILES CN1CCC(CC1)NC(=O)c1cc(c(Sc2c(Cl)cccc2Cl)s1)[N+]([O-])=O Show InChI InChI=1S/C17H17Cl2N3O3S2/c1-21-7-5-10(6-8-21)20-16(23)14-9-13(22(24)25)17(26-14)27-15-11(18)3-2-4-12(15)19/h2-4,9-10H,5-8H2,1H3,(H,20,23) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393440
(CHEMBL2159498)Show InChI InChI=1S/C12H7F2NO3S2/c1-6(16)11-5-9(15(17)18)12(20-11)19-10-3-2-7(13)4-8(10)14/h2-5H,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538571
(CHEMBL4635160)Show SMILES C[C@H]1CNCC[C@H]1Oc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4C(C3=O)C4(C)C)sc12 |r| Show InChI InChI=1S/C28H30ClN3O3S/c1-14-9-16(29)10-19(24(14)35-21-6-7-30-12-15(21)2)18-5-8-31-20-11-17(36-25(18)20)13-32-26(33)22-23(27(32)34)28(22,3)4/h5,8-11,15,21-23,30H,6-7,12-13H2,1-4H3/t15-,21+,22?,23?/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 4
(Homo sapiens (Human)) | BDBM50538571
(CHEMBL4635160)Show SMILES C[C@H]1CNCC[C@H]1Oc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4C(C3=O)C4(C)C)sc12 |r| Show InChI InChI=1S/C28H30ClN3O3S/c1-14-9-16(29)10-19(24(14)35-21-6-7-30-12-15(21)2)18-5-8-31-20-11-17(36-25(18)20)13-32-26(33)22-23(27(32)34)28(22,3)4/h5,8-11,15,21-23,30H,6-7,12-13H2,1-4H3/t15-,21+,22?,23?/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human 6His-tagged USP4 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1... |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 45
(Homo sapiens) | BDBM50538571
(CHEMBL4635160)Show SMILES C[C@H]1CNCC[C@H]1Oc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4C(C3=O)C4(C)C)sc12 |r| Show InChI InChI=1S/C28H30ClN3O3S/c1-14-9-16(29)10-19(24(14)35-21-6-7-30-12-15(21)2)18-5-8-31-20-11-17(36-25(18)20)13-32-26(33)22-23(27(32)34)28(22,3)4/h5,8-11,15,21-23,30H,6-7,12-13H2,1-4H3/t15-,21+,22?,23?/m0/s1 | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP45 (unknown origin) |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393438
(CHEMBL2159496)Show InChI InChI=1S/C12H9NO3S2/c1-8(14)11-7-10(13(15)16)12(18-11)17-9-5-3-2-4-6-9/h2-7H,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538559
(CHEMBL4642553)Show SMILES Clc1cc2C[C@@H](Oc2c(c1)-c1ccnc2cc(CN3CCCC3=O)sc12)C(=O)N1CCNCC1 |r| Show InChI InChI=1S/C25H25ClN4O3S/c26-16-10-15-11-21(25(32)29-8-5-27-6-9-29)33-23(15)19(12-16)18-3-4-28-20-13-17(34-24(18)20)14-30-7-1-2-22(30)31/h3-4,10,12-13,21,27H,1-2,5-9,11,14H2/t21-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50148911
((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |r,c:9| Show InChI InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1 | KEGG
UniProtKB/SwissProt
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CHEMBL
MCE
KEGG
PC cid
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PDB
UniChem
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Similars
| Article
PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Progenra, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) using Ub-AMC as substrate preincubated for 20 mins followed by substrate addition measured after 50 mins |
J Med Chem 61: 422-443 (2018)
Article DOI: 10.1021/acs.jmedchem.7b00498
BindingDB Entry DOI: 10.7270/Q2CR5WVG |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50393447
(CHEMBL2159506)Show InChI InChI=1S/C13H7Cl2NOS2/c1-7(17)12-4-8(6-16)13(19-12)18-11-3-2-9(14)5-10(11)15/h2-5H,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
| | n/a | n/a | >3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538552
(CHEMBL4636266)Show SMILES Clc1cc2C[C@@H](Oc2c(c1)-c1ccnc2ccsc12)C(=O)N1CCNCC1 |r| Show InChI InChI=1S/C20H18ClN3O2S/c21-13-9-12-10-17(20(25)24-6-4-22-5-7-24)26-18(12)15(11-13)14-1-3-23-16-2-8-27-19(14)16/h1-3,8-9,11,17,22H,4-7,10H2/t17-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
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AffyNet
| PC cid
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UniChem
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538554
(CHEMBL4643800)Show SMILES OCc1cc2nccc(-c3cc(Cl)cc4C[C@@H](Oc34)C(=O)N3CCNCC3)c2s1 |r| Show InChI InChI=1S/C21H20ClN3O3S/c22-13-7-12-8-18(21(27)25-5-3-23-4-6-25)28-19(12)16(9-13)15-1-2-24-17-10-14(11-26)29-20(15)17/h1-2,7,9-10,18,23,26H,3-6,8,11H2/t18-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538555
(CHEMBL4645724)Show SMILES OC1(COC1)c1cc2nccc(-c3cc(Cl)cc4C[C@@H](Oc34)C(=O)N3CCNCC3)c2s1 |r| Show InChI InChI=1S/C23H22ClN3O4S/c24-14-7-13-8-18(22(28)27-5-3-25-4-6-27)31-20(13)16(9-14)15-1-2-26-17-10-19(32-21(15)17)23(29)11-30-12-23/h1-2,7,9-10,18,25,29H,3-6,8,11-12H2/t18-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538556
(CHEMBL4646914)Show SMILES OCC(O)(CCl)c1cc2nccc(-c3cc(Cl)cc4C[C@@H](Oc34)C(=O)N3CCNCC3)c2s1 |r| Show InChI InChI=1S/C23H23Cl2N3O4S/c24-11-23(31,12-29)19-10-17-21(33-19)15(1-2-27-17)16-9-14(25)7-13-8-18(32-20(13)16)22(30)28-5-3-26-4-6-28/h1-2,7,9-10,18,26,29,31H,3-6,8,11-12H2/t18-,23?/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL5283229
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50270667
(CHEMBL4130194)Show SMILES CC(Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C24H27N3O3/c1-18(15-19-7-3-2-4-8-19)22(28)26-13-11-24(30,12-14-26)16-27-17-25-21-10-6-5-9-20(21)23(27)29/h2-10,17-18,30H,11-16H2,1H3 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
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UniChem
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Similars
| Article
PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538549
(CHEMBL4641424)Show SMILES Nc1cc(ccn1)-c1cc(Cl)cc2CC(Oc12)C(=O)N1CCNCC1 Show InChI InChI=1S/C18H19ClN4O2/c19-13-7-12-8-15(18(24)23-5-3-21-4-6-23)25-17(12)14(10-13)11-1-2-22-16(20)9-11/h1-2,7,9-10,15,21H,3-6,8H2,(H2,20,22) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538550
(CHEMBL4641014)Show SMILES Clc1cc2CC(Oc2c(c1)-c1ccnc2[nH]ccc12)C(=O)N1CCNCC1 Show InChI InChI=1S/C20H19ClN4O2/c21-13-9-12-10-17(20(26)25-7-5-22-6-8-25)27-18(12)16(11-13)14-1-3-23-19-15(14)2-4-24-19/h1-4,9,11,17,22H,5-8,10H2,(H,23,24) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538551
(CHEMBL4641037)Show SMILES Clc1cc2C[C@@H](Oc2c(c1)-c1ccnc2[nH]ccc12)C(=O)N1CCNCC1 |r| Show InChI InChI=1S/C20H19ClN4O2/c21-13-9-12-10-17(20(26)25-7-5-22-6-8-25)27-18(12)16(11-13)14-1-3-23-19-15(14)2-4-24-19/h1-4,9,11,17,22H,5-8,10H2,(H,23,24)/t17-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538553
(CHEMBL4643218)Show SMILES Cc1cc2nccc(-c3cc(Cl)cc4C[C@@H](Oc34)C(=O)N3CCNCC3)c2s1 |r| Show InChI InChI=1S/C21H20ClN3O2S/c1-12-8-17-20(28-12)15(2-3-24-17)16-11-14(22)9-13-10-18(27-19(13)16)21(26)25-6-4-23-5-7-25/h2-3,8-9,11,18,23H,4-7,10H2,1H3/t18-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50538558
(CHEMBL4641488)Show SMILES CC(=O)NCc1cc2nccc(-c3cc(Cl)cc4C[C@@H](Oc34)C(=O)N3CCNCC3)c2s1 |r| Show InChI InChI=1S/C23H23ClN4O3S/c1-13(29)27-12-16-11-19-22(32-16)17(2-3-26-19)18-10-15(24)8-14-9-20(31-21(14)18)23(30)28-6-4-25-5-7-28/h2-3,8,10-11,20,25H,4-7,9,12H2,1H3,(H,27,29)/t20-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of USP47 (unknown origin) by biochemical assay |
J Med Chem 63: 5398-5420 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00245
BindingDB Entry DOI: 10.7270/Q2XK8K2T |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL4516637
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50560592
(CHEMBL4742897) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of USP47 (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127471
BindingDB Entry DOI: 10.7270/Q20P13R0 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50560590
(CHEMBL4743789) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of USP47 (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127471
BindingDB Entry DOI: 10.7270/Q20P13R0 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50560585
(CHEMBL4787231) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of USP47 (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127471
BindingDB Entry DOI: 10.7270/Q20P13R0 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50560589
(CHEMBL4745448) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of USP47 (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127471
BindingDB Entry DOI: 10.7270/Q20P13R0 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50560588
(CHEMBL4761706) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of USP47 (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127471
BindingDB Entry DOI: 10.7270/Q20P13R0 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL5277194
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50560587
(CHEMBL4745914) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of USP47 (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127471
BindingDB Entry DOI: 10.7270/Q20P13R0 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL5274053
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL5286198
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | BDBM50560586
(CHEMBL4777703) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of USP47 (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127471
BindingDB Entry DOI: 10.7270/Q20P13R0 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL5276519
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL4438288
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 47
(Homo sapiens (Human)) | CHEMBL5270413
| KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
UniChem
| | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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