Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 3 [818-948,1003-1077]'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 [818-948,1003-1077] (Homo sapiens (Human))	BDBM176598 (US9120761, 12) Show SMILES CN1CCC(CC1)c1ccc(Nc2ncc(c(CCc3ccccc3CC(N)=O)n2)C(F)(F)F)c(C)c1 Show InChI InChI=1S/C28H32F3N5O/c1-18-15-22(20-11-13-36(2)14-12-20)8-9-24(18)34-27-33-17-23(28(29,30)31)25(35-27)10-7-19-5-3-4-6-21(19)16-26(32)37/h3-6,8-9,15,17,20H,7,10-14,16H2,1-2H3,(H2,32,37)(H,33,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 [818-948,1003-1077] (Homo sapiens (Human))	BDBM176587 (US9120761, 1) Show SMILES COc1cc(ccc1Nc1ncc(c(CCc2ccccc2CC(N)=O)n1)C(F)(F)F)N1CCNCC1 Show InChI InChI=1S/C26H29F3N6O2/c1-37-23-15-19(35-12-10-31-11-13-35)7-9-22(23)34-25-32-16-20(26(27,28)29)21(33-25)8-6-17-4-2-3-5-18(17)14-24(30)36/h2-5,7,9,15-16,31H,6,8,10-14H2,1H3,(H2,30,36)(H,32,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	275	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 [818-948,1003-1077] (Homo sapiens (Human))	BDBM176588 (US9120761, 2) Show SMILES COc1cc(ccc1Nc1ncc(c(CCc2ccccc2CC(N)=O)n1)C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C27H30F3N5O2/c1-37-24-14-20(18-10-12-32-13-11-18)7-9-23(24)35-26-33-16-21(27(28,29)30)22(34-26)8-6-17-4-2-3-5-19(17)15-25(31)36/h2-5,7,9,14,16,18,32H,6,8,10-13,15H2,1H3,(H2,31,36)(H,33,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.69E+3	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 [818-948,1003-1077] (Homo sapiens (Human))	BDBM176591 (US9120761, 5) Show SMILES COc1cc(ccc1Nc1ncc(c(CCc2cccc(c2)C(N)=O)n1)C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C26H28F3N5O2/c1-36-23-14-18(17-9-11-31-12-10-17)6-8-22(23)34-25-32-15-20(26(27,28)29)21(33-25)7-5-16-3-2-4-19(13-16)24(30)35/h2-4,6,8,13-15,17,31H,5,7,9-12H2,1H3,(H2,30,35)(H,32,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 [818-948,1003-1077] (Homo sapiens (Human))	BDBM176593 (US9120761, 7) Show SMILES CCN1CCC(CC1)c1ccc(Nc2ncc(c(Cc3ccccc3C(N)=O)n2)C(F)(F)F)c(OC)c1 Show InChI InChI=1S/C27H30F3N5O2/c1-3-35-12-10-17(11-13-35)18-8-9-22(24(15-18)37-2)33-26-32-16-21(27(28,29)30)23(34-26)14-19-6-4-5-7-20(19)25(31)36/h4-9,15-17H,3,10-14H2,1-2H3,(H2,31,36)(H,32,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	7.4	n/a
Cancer Therapeutics CRC PTY LTD US Patent					Assay Description Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...				US Patent US9120761 (2015) BindingDB Entry DOI: 10.7270/Q22N511J
					More data for this Ligand-Target Pair