Compile Data Set for Download or QSAR

Found 296 hits Enz. Inhib. hit(s) with Target = 'Monoacylglycerol lipase ABHD6' AND taxid = 10090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM26736 (CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phen...) Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H17N5O/c1-21(2)17(23)22-16(18-19-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	7.4	22
The Scripps Research Institute					Assay Description Serine hydrolase targets were recombinantly expressed in COS-7 cells by transient transfection. IC50 values were obtained by competitive ABPP with F...				J Am Chem Soc 128: 9699-704 (2006) Article DOI: 10.1021/ja062999h BindingDB Entry DOI: 10.7270/Q20K26VX
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010337 (CHEMBL3263582) Show SMILES OC(=O)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1Cc1ccccc1 Show InChI InChI=1S/C28H26N4O3/c33-27(34)24-10-6-9-23(18-24)21-12-14-22(15-13-21)26-19-32(30-29-26)28(35)31-16-5-4-11-25(31)17-20-7-2-1-3-8-20/h1-3,6-10,12-15,18-19,25H,4-5,11,16-17H2,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010336 (CHEMBL3263579) Show SMILES O=C(N1CCCCC1)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C32H33N5O2/c38-31(35-19-6-2-7-20-35)28-13-9-12-27(22-28)24-15-17-25(18-16-24)29-23-37(34-33-29)32(39)36-21-8-5-14-30(36)26-10-3-1-4-11-26/h1,3-4,9-13,15-18,22-23,30H,2,5-8,14,19-21H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010335 (CHEMBL3263577) Show SMILES OCc1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C27H26N4O2/c32-19-20-7-6-10-24(17-20)21-12-14-22(15-13-21)25-18-31(29-28-25)27(33)30-16-5-4-11-26(30)23-8-2-1-3-9-23/h1-3,6-10,12-15,17-18,26,32H,4-5,11,16,19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010336 (CHEMBL3263579) Show SMILES O=C(N1CCCCC1)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C32H33N5O2/c38-31(35-19-6-2-7-20-35)28-13-9-12-27(22-28)24-15-17-25(18-16-24)29-23-37(34-33-29)32(39)36-21-8-5-14-30(36)26-10-3-1-4-11-26/h1,3-4,9-13,15-18,22-23,30H,2,5-8,14,19-21H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assay				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010335 (CHEMBL3263577) Show SMILES OCc1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C27H26N4O2/c32-19-20-7-6-10-24(17-20)21-12-14-22(15-13-21)25-18-31(29-28-25)27(33)30-16-5-4-11-26(30)23-8-2-1-3-9-23/h1-3,6-10,12-15,17-18,26,32H,4-5,11,16,19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assay				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010337 (CHEMBL3263582) Show SMILES OC(=O)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1Cc1ccccc1 Show InChI InChI=1S/C28H26N4O3/c33-27(34)24-10-6-9-23(18-24)21-12-14-22(15-13-21)26-19-32(30-29-26)28(35)31-16-5-4-11-25(31)17-20-7-2-1-3-8-20/h1-3,6-10,12-15,18-19,25H,4-5,11,16-17H2,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assay				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010337 (CHEMBL3263582) Show SMILES OC(=O)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1Cc1ccccc1 Show InChI InChI=1S/C28H26N4O3/c33-27(34)24-10-6-9-23(18-24)21-12-14-22(15-13-21)26-19-32(30-29-26)28(35)31-16-5-4-11-25(31)17-20-7-2-1-3-8-20/h1-3,6-10,12-15,18-19,25H,4-5,11,16-17H2,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010336 (CHEMBL3263579) Show SMILES O=C(N1CCCCC1)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C32H33N5O2/c38-31(35-19-6-2-7-20-35)28-13-9-12-27(22-28)24-15-17-25(18-16-24)29-23-37(34-33-29)32(39)36-21-8-5-14-30(36)26-10-3-1-4-11-26/h1,3-4,9-13,15-18,22-23,30H,2,5-8,14,19-21H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010335 (CHEMBL3263577) Show SMILES OCc1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C27H26N4O2/c32-19-20-7-6-10-24(17-20)21-12-14-22(15-13-21)25-18-31(29-28-25)27(33)30-16-5-4-11-26(30)23-8-2-1-3-9-23/h1-3,6-10,12-15,17-18,26,32H,4-5,11,16,19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010337 (CHEMBL3263582) Show SMILES OC(=O)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1Cc1ccccc1 Show InChI InChI=1S/C28H26N4O3/c33-27(34)24-10-6-9-23(18-24)21-12-14-22(15-13-21)26-19-32(30-29-26)28(35)31-16-5-4-11-25(31)17-20-7-2-1-3-8-20/h1-3,6-10,12-15,18-19,25H,4-5,11,16-17H2,(H,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50052782 (CHEMBL3318604) Show SMILES Cc1cnn(c1)C(=O)N1CCN(Cc2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C20H22N4O/c1-16-13-21-24(14-16)20(25)23-10-8-22(9-11-23)15-17-6-7-18-4-2-3-5-19(18)12-17/h2-7,12-14H,8-11,15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50052783 (CHEMBL3318605) Show SMILES O=C(N1CCN(Cc2ccc3ccccc3c2)CC1)n1cc(cn1)C#N Show InChI InChI=1S/C20H19N5O/c21-12-17-13-22-25(15-17)20(26)24-9-7-23(8-10-24)14-16-5-6-18-3-1-2-4-19(18)11-16/h1-6,11,13,15H,7-10,14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50052768 (CHEMBL3318613) Show SMILES O=C(N1CCN(Cc2ccc(OCc3ccccc3)cc2)CC1)n1cc(cn1)C#N Show InChI InChI=1S/C23H23N5O2/c24-14-21-15-25-28(17-21)23(29)27-12-10-26(11-13-27)16-19-6-8-22(9-7-19)30-18-20-4-2-1-3-5-20/h1-9,15,17H,10-13,16,18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50052781 (CHEMBL3318603) Show SMILES O=C(N1CCN(Cc2ccc3ccccc3c2)CC1)n1cccn1 Show InChI InChI=1S/C19H20N4O/c24-19(23-9-3-8-20-23)22-12-10-21(11-13-22)15-16-6-7-17-4-1-2-5-18(17)14-16/h1-9,14H,10-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50052767 (CHEMBL3318612) Show SMILES Cc1cnn(c1)C(=O)N1CCN(Cc2ccc(OCc3ccccc3)cc2)CC1 Show InChI InChI=1S/C23H26N4O2/c1-19-15-24-27(16-19)23(28)26-13-11-25(12-14-26)17-20-7-9-22(10-8-20)29-18-21-5-3-2-4-6-21/h2-10,15-16H,11-14,17-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010336 (CHEMBL3263579) Show SMILES O=C(N1CCCCC1)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C32H33N5O2/c38-31(35-19-6-2-7-20-35)28-13-9-12-27(22-28)24-15-17-25(18-16-24)29-23-37(34-33-29)32(39)36-21-8-5-14-30(36)26-10-3-1-4-11-26/h1,3-4,9-13,15-18,22-23,30H,2,5-8,14,19-21H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50010335 (CHEMBL3263577) Show SMILES OCc1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1 Show InChI InChI=1S/C27H26N4O2/c32-19-20-7-6-10-24(17-20)21-12-14-22(15-13-21)25-18-31(29-28-25)27(33)30-16-5-4-11-26(30)23-8-2-1-3-9-23/h1-3,6-10,12-15,17-18,26,32H,4-5,11,16,19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...				Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50608631 (CHEMBL5274434) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307083 (4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carb...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cccc(Oc4ccccc4)c3)CC2)cc1 Show InChI InChI=1S/C24H23N3O5/c28-24(32-22-11-9-20(10-12-22)27(29)30)26-15-13-25(14-16-26)18-19-5-4-8-23(17-19)31-21-6-2-1-3-7-21/h1-12,17H,13-16,18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50211271 (CHEMBL3913807) Show SMILES CO[C@@H]1CC[C@H](Cc2ccccc2)N(C1)C(=O)n1ncc(n1)C(O)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H28F2N4O3/c1-38-26-16-15-25(17-20-5-3-2-4-6-20)34(19-26)28(36)35-32-18-27(33-35)29(37,21-7-11-23(30)12-8-21)22-9-13-24(31)14-10-22/h2-14,18,25-26,37H,15-17,19H2,1H3/t25-,26-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of MB064 probe binding to ABHD6 in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after ...				J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50052760 (CHEMBL3318590) Show SMILES O=C(N1CCCCC1)n1cc(cn1)C#N Show InChI InChI=1S/C10H12N4O/c11-6-9-7-12-14(8-9)10(15)13-4-2-1-3-5-13/h7-8H,1-5H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307086 (4-Nitrophenyl 4-(3-(Pyridin-2-yloxy)benzyl)piperaz...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cccc(Oc4ccccn4)c3)CC2)cc1 Show InChI InChI=1S/C23H22N4O5/c28-23(32-20-9-7-19(8-10-20)27(29)30)26-14-12-25(13-15-26)17-18-4-3-5-21(16-18)31-22-6-1-2-11-24-22/h1-11,16H,12-15,17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50211257 (CHEMBL3895863 | US10583137, Compound 14) Show SMILES OC(c1cnn(n1)C(=O)N1C[C@@H](CC[C@@H]1Cc1ccccc1)OCC#C)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C31H28F2N4O3/c1-2-18-40-28-17-16-27(19-22-6-4-3-5-7-22)36(21-28)30(38)37-34-20-29(35-37)31(39,23-8-12-25(32)13-9-23)24-10-14-26(33)15-11-24/h1,3-15,20,27-28,39H,16-19,21H2/t27-,28-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of MB064 probe binding to ABHD6 in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after ...				J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM434879 (US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...) Show SMILES CC(C)(C)OC(=O)N1CCN(C(Cc2ccccc2)C1)C(=O)n1cc(nn1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C26H28F3N5O4/c1-25(2,3)38-24(36)32-13-14-33(20(16-32)15-18-7-5-4-6-8-18)23(35)34-17-22(30-31-34)19-9-11-21(12-10-19)37-26(27,28)29/h4-12,17,20H,13-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50505180 (CHEMBL4462665) Show SMILES O=C(N1CCCN(Cc2ccc(OCc3ccccc3)cc2)CC1)n1cc(cn1)C#N Show InChI InChI=1S/C24H25N5O2/c25-15-22-16-26-29(18-22)24(30)28-12-4-11-27(13-14-28)17-20-7-9-23(10-8-20)31-19-21-5-2-1-3-6-21/h1-3,5-10,16,18H,4,11-14,17,19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280615 (US10030020, Example 160 | US10781211, Example 160) Show SMILES CC(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1 Show InChI InChI=1S/C24H29F6N3O3/c1-16(34)33-9-5-17-3-2-4-18(19(17)14-33)13-31-10-6-22(15-31)7-11-32(12-8-22)21(35)36-20(23(25,26)27)24(28,29)30/h2-4,20H,5-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280616 (US10030020, Example 161 | US10781211, Example 161) Show SMILES CS(=O)(=O)N1CCc2cccc(CN3CCC4(C3)CCN(CC4)C(=O)OC(C(F)(F)F)C(F)(F)F)c2C1 Show InChI InChI=1S/C23H29F6N3O4S/c1-37(34,35)32-9-5-16-3-2-4-17(18(16)14-32)13-30-10-6-21(15-30)7-11-31(12-8-21)20(33)36-19(22(24,25)26)23(27,28)29/h2-4,19H,5-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280608 (US10030020, Example 153 | US10781211, Example 153) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCN(Cc3ccc4COCc4c3)C2)CC1)C(F)(F)F Show InChI InChI=1S/C21H24F6N2O3/c22-20(23,24)17(21(25,26)27)32-18(30)29-7-4-19(5-8-29)3-6-28(13-19)10-14-1-2-15-11-31-12-16(15)9-14/h1-2,9,17H,3-8,10-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280592 (US10030020, Example 137 | US10781211, Example 137) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCN(Cc3ccc4OCCOc4c3)C2)CC1)C(F)(F)F Show InChI InChI=1S/C21H24F6N2O4/c22-20(23,24)17(21(25,26)27)33-18(30)29-7-4-19(5-8-29)3-6-28(13-19)12-14-1-2-15-16(11-14)32-10-9-31-15/h1-2,11,17H,3-10,12-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM280593 (US10030020, Example 138 | US10781211, Example 138) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCN(Cc3ccc(N4CCOCC4)c(Cl)c3)C2)CC1)C(F)(F)F Show InChI InChI=1S/C23H28ClF6N3O3/c24-17-13-16(1-2-18(17)32-9-11-35-12-10-32)14-31-6-3-21(15-31)4-7-33(8-5-21)20(34)36-19(22(25,26)27)23(28,29)30/h1-2,13,19H,3-12,14-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50211257 (CHEMBL3895863 | US10583137, Compound 14) Show SMILES OC(c1cnn(n1)C(=O)N1C[C@@H](CC[C@@H]1Cc1ccccc1)OCC#C)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C31H28F2N4O3/c1-2-18-40-28-17-16-27(19-22-6-4-3-5-7-22)36(21-28)30(38)37-34-20-29(35-37)31(39,23-8-12-25(32)13-9-23)24-10-14-26(33)15-11-24/h1,3-15,20,27-28,39H,16-19,21H2/t27-,28-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars		n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307088 (4-Nitrophenyl 4-(5-Bromo-2-hydroxybenzyl)piperazin...) Show SMILES Oc1ccc(Br)cc1CN1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C18H18BrN3O5/c19-14-1-6-17(23)13(11-14)12-20-7-9-21(10-8-20)18(24)27-16-4-2-15(3-5-16)22(25)26/h1-6,11,23H,7-10,12H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307087 (4-Nitrophenyl 4-(Naphthalen-2-ylmethyl)piperazine-...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc4ccccc4c3)CC2)cc1 Show InChI InChI=1S/C22H21N3O4/c26-22(29-21-9-7-20(8-10-21)25(27)28)24-13-11-23(12-14-24)16-17-5-6-18-3-1-2-4-19(18)15-17/h1-10,15H,11-14,16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307090 (4-Nitrophenyl 4-(Bis(4-chlorophenyl)(hydroxy)methy...) Show SMILES OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H22Cl2N2O5/c26-20-5-1-17(2-6-20)25(31,18-3-7-21(27)8-4-18)19-13-15-28(16-14-19)24(30)34-23-11-9-22(10-12-23)29(32)33/h1-12,19,31H,13-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307081 (4-Nitrophenyl 4-((5-(2-(Trifluoromethoxy)phenyl)fu...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc(o3)-c3ccccc3OC(F)(F)F)CC2)cc1 Show InChI InChI=1S/C23H20F3N3O6/c24-23(25,26)35-21-4-2-1-3-19(21)20-10-9-18(33-20)15-27-11-13-28(14-12-27)22(30)34-17-7-5-16(6-8-17)29(31)32/h1-10H,11-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307085 (4-Nitrophenyl 4-((5-Phenylthiophen-2-yl)methyl)pip...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc(s3)-c3ccccc3)CC2)cc1 Show InChI InChI=1S/C22H21N3O4S/c26-22(29-19-8-6-18(7-9-19)25(27)28)24-14-12-23(13-15-24)16-20-10-11-21(30-20)17-4-2-1-3-5-17/h1-11H,12-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307084 (4-Nitrophenyl 4-((5-Phenylfuran-2-yl)methyl)pipera...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc(o3)-c3ccccc3)CC2)cc1 Show InChI InChI=1S/C22H21N3O5/c26-22(30-19-8-6-18(7-9-19)25(27)28)24-14-12-23(13-15-24)16-20-10-11-21(29-20)17-4-2-1-3-5-17/h1-11H,12-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50052766 (CHEMBL3318611) Show SMILES O=C(N1CCN(Cc2ccc(OCc3ccccc3)cc2)CC1)n1cccn1 Show InChI InChI=1S/C22H24N4O2/c27-22(26-12-4-11-23-26)25-15-13-24(14-16-25)17-19-7-9-21(10-8-19)28-18-20-5-2-1-3-6-20/h1-12H,13-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307089 (4-Nitrophenyl 4-(4-(Benzyloxy)-2-methoxybenzyl)pip...) Show SMILES COc1cc(OCc2ccccc2)ccc1CN1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C26H27N3O6/c1-33-25-17-24(34-19-20-5-3-2-4-6-20)10-7-21(25)18-27-13-15-28(16-14-27)26(30)35-23-11-8-22(9-12-23)29(31)32/h2-12,17H,13-16,18-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50211240 (CHEMBL3897587) Show SMILES OC(c1cnn(n1)C(=O)N1C[C@@H](CC[C@@H]1Cc1ccccc1)OCC1CC1)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C32H32F2N4O3/c33-26-12-8-24(9-13-26)32(40,25-10-14-27(34)15-11-25)30-19-35-38(36-30)31(39)37-20-29(41-21-23-6-7-23)17-16-28(37)18-22-4-2-1-3-5-22/h1-5,8-15,19,23,28-29,40H,6-7,16-18,20-21H2/t28-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of MB064 probe binding to ABHD6 in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after ...				J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307082 (4-Nitrophenyl 4-(3-(3-(Trifluoromethyl)phenoxy)ben...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cccc(Oc4cccc(c4)C(F)(F)F)c3)CC2)cc1 Show InChI InChI=1S/C25H22F3N3O5/c26-25(27,28)19-4-2-6-23(16-19)35-22-5-1-3-18(15-22)17-29-11-13-30(14-12-29)24(32)36-21-9-7-20(8-10-21)31(33)34/h1-10,15-16H,11-14,17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50505189 (CHEMBL4527008) Show SMILES CN(CCN(C)C(=O)n1cc(cn1)C#N)Cc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C23H25N5O2/c1-26(12-13-27(2)23(29)28-17-21(14-24)15-25-28)16-19-8-10-22(11-9-19)30-18-20-6-4-3-5-7-20/h3-11,15,17H,12-13,16,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307091 (4-Nitrophenyl 2,2-Diphenyl-1-oxa-6-azaspiro[2.5]oc...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCC3(CC2)OC3(c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C25H22N2O5/c28-23(31-22-13-11-21(12-14-22)27(29)30)26-17-15-24(16-18-26)25(32-24,19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-14H,15-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50211262 (CHEMBL3922787) Show SMILES CO[C@H]1CC[C@H](Cc2ccccc2)N(C1)C(=O)n1ncc(n1)C(O)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H28F2N4O3/c1-38-26-16-15-25(17-20-5-3-2-4-6-20)34(19-26)28(36)35-32-18-27(33-35)29(37,21-7-11-23(30)12-8-21)22-9-13-24(31)14-10-22/h2-14,18,25-26,37H,15-17,19H2,1H3/t25-,26+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of MB064 probe binding to ABHD6 in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after ...				J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50608629 (CHEMBL4303532) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307059 (4-Nitrophenyl 4-(3-(4-Methoxyphenoxy)benzyl)pipera...) Show SMILES COc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Oc3ccc(cc3)[N+]([O-])=O)c2)cc1 Show InChI InChI=1S/C25H25N3O6/c1-32-21-9-11-22(12-10-21)33-24-4-2-3-19(17-24)18-26-13-15-27(16-14-26)25(29)34-23-7-5-20(6-8-23)28(30)31/h2-12,17H,13-16,18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307058 (4-Nitrophenyl 4-(Hydroxybis(3-methoxyphenyl)methyl...) Show SMILES COc1cccc(c1)C(O)(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)c1cccc(OC)c1 Show InChI InChI=1S/C27H28N2O7/c1-34-24-7-3-5-20(17-24)27(31,21-6-4-8-25(18-21)35-2)19-13-15-28(16-14-19)26(30)36-23-11-9-22(10-12-23)29(32)33/h3-12,17-19,31H,13-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50307060 (4-Nitrophenyl 4-(Quinolin-2-ylmethyl)piperazine-1-...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc4ccccc4n3)CC2)cc1 Show InChI InChI=1S/C21H20N4O4/c26-21(29-19-9-7-18(8-10-19)25(27)28)24-13-11-23(12-14-24)15-17-6-5-16-3-1-2-4-20(16)22-17/h1-10H,11-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ABHD6 in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse))	BDBM50505184 (CHEMBL4553954) Show SMILES CN(CCN(C)C(=O)n1cccn1)Cc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C22H26N4O2/c1-24(15-16-25(2)22(27)26-14-6-13-23-26)17-19-9-11-21(12-10-19)28-18-20-7-4-3-5-8-20/h3-14H,15-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...				Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 BindingDB Entry DOI: 10.7270/Q2RX9GCW
					More data for this Ligand-Target Pair

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